| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mathieu Nollet, Philippe Gaillard, Frédéric Minier, Arnaud Tanti, Catherine Belzung, Samuel Lema. Activation of orexin neurons in dorsomedial/perifornical hypothalamus and antidepressant reversal in a rodent model of depression. Neuropharmacology. vol 61. issue 1-2. 2012-04-17. PMID:21530551. |
using double immunohistochemical labeling for ox- or mch-containing neurons and fos protein, we studied the effects of a chronic selective serotonin reuptake inhibitor antidepressant treatment (fluoxetine) on the ox and mch neuronal activation in mice exposed to unpredictable chronic mild stress (ucms), a rodent model of depression. |
2012-04-17 |
2023-08-12 |
mouse |
| M S Harbuz, D S Jesso. Stress and inflammatory disease: widening roles for serotonin and substance P. Stress (Amsterdam, Netherlands). vol 4. issue 1. 2012-04-16. PMID:22432127. |
stress and inflammatory disease: widening roles for serotonin and substance p. serotonin has been implicated in mediating the hypothalamo-pituitary-adrenal (hpa) axis response to stress and is an important therapeutic target for a number of psychiatric disorders including depression. |
2012-04-16 |
2023-08-12 |
rat |
| Erika Comasco, Sara M Sylvén, Fotios C Papadopoulos, Lars Oreland, Inger Sundström-Poromaa, Alkistis Skalkido. Postpartum depressive symptoms and the BDNF Val66Met functional polymorphism: effect of season of delivery. Archives of women's mental health. vol 14. issue 6. 2012-04-12. PMID:21997575. |
candidate genes, such as those encoding for the brain-derived neurotrophic factor (bdnf), serotonin transporter (5-htt), and period2 (per2), have been associated with depression and seasonal disorders. |
2012-04-12 |
2023-08-12 |
Not clear |
| Natalia Jaworska, Andrea Thompson, Dhrasti Shah, Derek Fisher, Vadim Ilivitsky, Verner Knot. Acute tryptophan depletion effects on the vertex and late positive potentials to emotional faces in individuals with a family history of depression. Neuropsychobiology. vol 65. issue 1. 2012-04-10. PMID:22094352. |
this study assessed the effects of acute tryptophan depletion (trp-), which transiently lowers cns 5-ht, on the emotion-sensitive vertex positive potential (vpp) and late positive potential (lpp) event-related potentials (erps) and mood in individuals with a family history of depression. |
2012-04-10 |
2023-08-12 |
Not clear |
| Stania A DeJesus, Vanessa A Diaz, Wanda C Gonsalves, Peter J Care. Identification and treatment of depression in minority populations. International journal of psychiatry in medicine. vol 42. issue 1. 2012-04-05. PMID:22372025. |
selective serotonin reuptake inhibitors (ssris) have become the cornerstone of therapy for depression since the food and drug administration (fda) approval of fluoxetine in 1987. |
2012-04-05 |
2023-08-12 |
Not clear |
| E Alison Holman, Rachel G Lucas-Thompson, Tammy L. Social constraints, genetic vulnerability, and mental health following collective stress. Journal of traumatic stress. vol 24. issue 5. 2012-04-04. PMID:22095773. |
a repeat-length polymorphism of the serotonin promoter gene (5-httlpr) has been associated with depression and posttraumatic stress disorder (ptsd) in trauma-exposed individuals reporting unsupportive social environments. |
2012-04-04 |
2023-08-12 |
Not clear |
| Gwenn S Smith, Alan Kahn, Julia Sacher, Pablo Rusjan, Thilo van Eimeren, Alastair Flint, Alan A Wilso. Serotonin transporter occupancy and the functional neuroanatomic effects of citalopram in geriatric depression. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 19. issue 12. 2012-04-03. PMID:21841458. |
serotonin transporter occupancy and the functional neuroanatomic effects of citalopram in geriatric depression. |
2012-04-03 |
2023-08-12 |
Not clear |
| Gwenn S Smith, Alan Kahn, Julia Sacher, Pablo Rusjan, Thilo van Eimeren, Alastair Flint, Alan A Wilso. Serotonin transporter occupancy and the functional neuroanatomic effects of citalopram in geriatric depression. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 19. issue 12. 2012-04-03. PMID:21841458. |
the functional neuroanatomic changes associated with selective serotonin reuptake inhibitor (ssri) treatment have been the focus of positron emission tomography (pet) studies of cerebral glucose metabolism in geriatric depression. |
2012-04-03 |
2023-08-12 |
Not clear |
| Clement Hamani, Danilo C Machado, Débora C Hipólide, Francisco P Dubiela, Deborah Suchecki, Carlos E Macedo, Fabio Tescarollo, Uilton Martins, Luciene Covolan, José N Nobreg. Deep brain stimulation reverses anhedonic-like behavior in a chronic model of depression: role of serotonin and brain derived neurotrophic factor. Biological psychiatry. vol 71. issue 1. 2012-03-30. PMID:22000731. |
deep brain stimulation reverses anhedonic-like behavior in a chronic model of depression: role of serotonin and brain derived neurotrophic factor. |
2012-03-30 |
2023-08-12 |
Not clear |
| Dasiel O Borroto-Escuela, Wilber Romero-Fernandez, Giuseppa Mudó, Mileidys Pérez-Alea, Francisco Ciruela, Alexander O Tarakanov, Manuel Narvaez, Valentina Di Liberto, Luigi F Agnati, Natale Belluardo, Kjell Fux. Fibroblast growth factor receptor 1- 5-hydroxytryptamine 1A heteroreceptor complexes and their enhancement of hippocampal plasticity. Biological psychiatry. vol 71. issue 1. 2012-03-30. PMID:22035699. |
the hippocampus and its 5-hydroxytryptamine transmission plays an important role in depression related to its involvement in limbic circuit plasticity. |
2012-03-30 |
2023-08-12 |
Not clear |
| Bernardo Dell'Osso, M Carlotta Palazzo, Lucio Oldani, A Carlo Altamur. The noradrenergic action in antidepressant treatments: pharmacological and clinical aspects. CNS neuroscience & therapeutics. vol 17. issue 6. 2012-03-25. PMID:21155988. |
even though noradrenaline has been recognized as one of the key neurotransmitters in the pathophysiology of major depression (md), noradrenergic compounds have been less extensively utilized in clinical practice, compared to selective serotonin reuptake inhibitors (ssris). |
2012-03-25 |
2023-08-12 |
human |
| E K Sawyer, L L Howel. Pharmacokinetics of fluoxetine in rhesus macaques following multiple routes of administration. Pharmacology. vol 88. issue 1-2. 2012-03-25. PMID:21757974. |
fluoxetine (prozac) is a selective serotonin reuptake inhibitor currently used to treat depression and mood disorders. |
2012-03-25 |
2023-08-12 |
Not clear |
| Koen Demyttenaer. Agomelatine: a narrative review. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 21 Suppl 4. 2012-03-25. PMID:21835598. |
results from clinical trials with agomelatine, a melatonergic receptor agonist (mt(1)/mt(2)) and 5ht(2c) receptor antagonist, have shown that it is efficacious in both the acute phase and the continuation phase of treatment of depression. |
2012-03-25 |
2023-08-12 |
Not clear |
| David T Chau, Pedro V Rada, Kay Kim, Rebecca A Kosloff, Bartley G Hoebe. Fluoxetine alleviates behavioral depression while decreasing acetylcholine release in the nucleus accumbens shell. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 8. 2012-03-22. PMID:21525864. |
selective serotonin reuptake inhibitors, such as fluoxetine, have demonstrated the ability to alleviate behavioral depression in the forced swim test; however, the sites and mechanisms of their actions remain to be further elucidated. |
2012-03-22 |
2023-08-12 |
Not clear |
| Yunxiang Su, Ling Xu. [Effects of jingqianshu granule on expression of 5-HT(1A)R of PMS model rats with liver-qi stagnation]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 36. issue 24. 2012-03-20. PMID:22368865. |
to research the effect of the jingqianshu granule (jqs) on the expression of serotonin receptor-1a (5-ht(1a)r) in hippocampus and hypothalamus of premenstrual syndrome (pms) model rats with liver-qi depression. |
2012-03-20 |
2023-08-12 |
rat |
| Michael E Thas. Are SNRIs more effective than SSRIs? A review of the current state of the controversy. Psychopharmacology bulletin. vol 41. issue 2. 2012-03-13. PMID:18668017. |
there is evidence from inpatient studies dating to 1986, however, suggesting that the tricyclic antidepressant clomipramine, which inhibits reuptake of both serotonin and norepinephrine, may have greater efficacy than some ssris for severe depression. |
2012-03-13 |
2023-08-12 |
Not clear |
| b' Giorgio Giardina, Riccardo Montioli, Stefano Gianni, Barbara Cellini, Alessandro Paiardini, Carla Borri Voltattorni, Francesca Cutruzzol\\xc3\\xa. Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 51. 2012-03-09. PMID:22143761.' |
dopa decarboxylase, the dimeric enzyme responsible for the synthesis of neurotransmitters dopamine and serotonin, is involved in severe neurological diseases such as parkinson disease, schizophrenia, and depression. |
2012-03-09 |
2023-08-12 |
human |
| Saima Khaliq, Saida Haider, Faizan Naqvi, Tahira Perveen, Sadia Saleem, Darakhshan Jabeen Halee. Altered brain serotonergic neurotransmission following caffeine withdrawal produces behavioral deficits in rats. Pakistan journal of pharmaceutical sciences. vol 25. issue 1. 2012-03-08. PMID:22186305. |
a role of decreased brain 5-ht (5-hydroxytryptamine, serotonin) levels has been implicated in impaired cognitive performance and depression. |
2012-03-08 |
2023-08-12 |
rat |
| Xin-jun Wang, Ling-ling Wan. [A mechanism of endogenous opioid peptides for rapid onset of acupuncture effect in treatment of depression]. Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine. vol 8. issue 11. 2012-03-06. PMID:21078263. |
clinical and experimental studies show that the onset of effect of acupuncture on depression is more rapid than selective serotonin reuptake inhibitors, a class of antidepressants. |
2012-03-06 |
2023-08-12 |
Not clear |
| Agustina Falibene, Wolfgang Rössler, Roxana Josen. Serotonin depresses feeding behaviour in ants. Journal of insect physiology. vol 58. issue 1. 2012-03-01. PMID:21893064. |
our results show that 5-ht promotes a dose-dependent depression of sucrose feeding in camponotus mus ants. |
2012-03-01 |
2023-08-12 |
Not clear |