| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| F Leblhuber, K Steiner, Dietmar Fuch. Treatment of patients with geriatric depression with repetitive transcranial magnetic stimulation. Journal of neural transmission (Vienna, Austria : 1996). vol 126. issue 8. 2020-07-28. PMID:31250285. |
in this sham-controlled exploratory study safety, symptom improvement as well as changes in inflammation markers and neurotransmitter precursor amino acids availability were studied after a prefrontal cortex (pfc) stimulation using rtms as add-on treatment in 29 patients with geriatric depression. |
2020-07-28 |
2023-08-13 |
Not clear |
| F Leblhuber, K Steiner, Dietmar Fuch. Treatment of patients with geriatric depression with repetitive transcranial magnetic stimulation. Journal of neural transmission (Vienna, Austria : 1996). vol 126. issue 8. 2020-07-28. PMID:31250285. |
in addition to the significant effect of rtms on depression scores, these results point to a possible influence of rtms on the enzyme phenylalanine hydroxylase (pah), which plays a crucial role in the biosynthesis of neurotransmitter precursors related to geriatric depression. |
2020-07-28 |
2023-08-13 |
Not clear |
| Olivia G Swann, Michelle Kilpatrick, Monique Breslin, Wendy H Odd. Dietary fiber and its associations with depression and inflammation. Nutrition reviews. vol 78. issue 5. 2020-07-17. PMID:31750916. |
the resultant reduction in inflammatory compounds may alter neurotransmitter concentrations to reduce symptoms of depression. |
2020-07-17 |
2023-08-13 |
Not clear |
| Daniel Worms, Barbara Maertens, Jan Kubicek, Udaya Kumar Tiruttani Subhramanyam, Jörg Labah. Expression, purification and stabilization of human serotonin transporter from E. coli. Protein expression and purification. vol 164. 2020-07-06. PMID:31442583. |
the serotonin transporter belongs to the family of sodium-chloride coupled neurotransmitter transporter and is related to depression in humans. |
2020-07-06 |
2023-08-13 |
human |
| Xin Wang, Ping Li, Qi Ding, Chuanchen Wu, Wen Zhang, Bo Tan. Observation of Acetylcholinesterase in Stress-Induced Depression Phenotypes by Two-Photon Fluorescence Imaging in the Mouse Brain. Journal of the American Chemical Society. vol 141. issue 5. 2020-05-27. PMID:30638380. |
oxidative stress in depression is a prime cause of neurotransmitter metabolism dysfunction in the brain. |
2020-05-27 |
2023-08-13 |
mouse |
| Bogna Grygiel-Górniak, Nattakarn Limphaibool, Mariusz Puszczewic. Cytokine secretion and the risk of depression development in patients with connective tissue diseases. Psychiatry and clinical neurosciences. vol 73. issue 6. 2020-04-21. PMID:30719813. |
inflammation is thought to contribute to the development of clinical depression through its ability to induce sickness behaviors corresponding to the neurovegetative features of depression, through the dysregulation of the hypothalamic-pituitary-adrenal axis, alterations in neurotransmitter synthesis and reuptake, and through its involvement in the neuroprogression pathways. |
2020-04-21 |
2023-08-13 |
Not clear |
| Stephanie C Dulawa, David S Janowsk. Cholinergic regulation of mood: from basic and clinical studies to emerging therapeutics. Molecular psychiatry. vol 24. issue 5. 2020-03-03. PMID:30120418. |
the neurobiological mechanisms underlying depression remain poorly understood, although theories regarding dysfunction within various neurotransmitter systems have been postulated. |
2020-03-03 |
2023-08-13 |
human |
| Lian Beijers, Klaas J Wardenaar, Hanna M van Loo, Robert A Schoever. Data-driven biological subtypes of depression: systematic review of biological approaches to depression subtyping. Molecular psychiatry. vol 24. issue 6. 2020-03-02. PMID:30824865. |
five out of six biochemical studies indicated that there might be depression subtypes with and without disturbed neurotransmitter levels, and one indicated there might be an inflammatory subtype. |
2020-03-02 |
2023-08-13 |
human |
| Rachel A Daut, Laura K Fonke. Circadian regulation of depression: A role for serotonin. Frontiers in neuroendocrinology. vol 54. 2020-03-02. PMID:31002895. |
stress is a common etiological factor in the development of depression and the circadian system is highly interconnected to stress-sensitive neurotransmitter systems such as the serotonin (5-hydroxytryptamine, 5-ht) system. |
2020-03-02 |
2023-08-13 |
Not clear |
| Alaeddine Djillani, Mariel Pietri, Jean Mazella, Catherine Heurteaux, Marc Borsott. Fighting against depression with TREK-1 blockers: Past and future. A focus on spadin. Pharmacology & therapeutics. vol 194. 2020-02-28. PMID:30291907. |
the neurobiological mechanisms of depression are not fully understood, but evidence highlights the role of monoamine neurotransmitter balance. |
2020-02-28 |
2023-08-13 |
Not clear |
| Daehyuk Jang, Hyun-Ju Lee, Kyungjun Lee, Kyu-Ri Kim, Ran Won, Seung Eun Lee, Insop Shi. White Ginseng Ameliorates Depressive Behavior and Increases Hippocampal 5-HT Level in the Stressed Ovariectomized Rats. BioMed research international. vol 2019. 2020-02-26. PMID:31612144. |
postmenopausal depression is closely associated with depletion of estrogen which modulates transmission of 5-ht, a key neurotransmitter that regulates stress-managing circuits in the brain. |
2020-02-26 |
2023-08-13 |
rat |
| Kedong Xu, Pingping Li, Yi Miao, Nan Dong, Jianbo Zhang, Shuguang Wei, Shengbin Li, Fang Ca. Effects of ovarian hormones on emotional behaviors in dopamine D3 receptor knockout mice. Physiology & behavior. vol 198. 2020-02-17. PMID:30292827. |
however, the functions of ovarian hormones in neurotransmitter signaling must be identified to understand their role in anxiety and depression. |
2020-02-17 |
2023-08-13 |
mouse |
| Fangli Zhao, Jason J Siu, Wei Huang, Candice Askwith, Lei Ca. Insulin Modulates Excitatory Synaptic Transmission and Synaptic Plasticity in the Mouse Hippocampus. Neuroscience. vol 411. 2020-02-04. PMID:31146008. |
although insulin-induced inhibition of field excitatory post-synaptic potentials (fepsps) was previously termed insulin-long-term depression (insulin-ltd), insulin application potentiated recovery from classically induced ltd. further analysis suggests suppression of presynaptic neurotransmitter release contributed to the insulin-ltd. at low concentrations, insulin primarily inhibited fepsps; however, at high concentration, its effects were of mixed inhibition and enhancement in different recordings. |
2020-02-04 |
2023-08-13 |
mouse |
| Kamilla A Mukhutdinova, Marat R Kasimov, Guzel F Zakyrjanova, Milausha R Gumerova, Alexey M Petro. Oxysterol modulates neurotransmission via liver-X receptor/NO synthase-dependent pathway at the mouse neuromuscular junctions. Neuropharmacology. vol 150. 2020-01-21. PMID:30898570. |
24s-hch enhanced the depression of epp amplitude (indicator of neurotransmitter release) and suppressed the fm1-43 dye unloading from nerve terminals (indicator of exocytosis) during electrical nerve stimulation at 20 hz, without affecting miniature epp amplitude and frequency. |
2020-01-21 |
2023-08-13 |
mouse |
| Ning Jiang, Jing-Wei Lv, Hai-Xia Wang, Qiong Wang, Cong Lu, Yu-Jie Yang, Hong Huang, Tian-Ji Xia, Guang-Hua Lv, Xin-Min Li. Antidepressant-like effects of 20(S)-protopanaxadiol in a mouse model of chronic social defeat stress and the related mechanisms. Phytotherapy research : PTR. vol 33. issue 10. 2019-12-26. PMID:31353678. |
our results suggest that ppd exerts antidepressant-like effects in mice with csds-induced depression and that this effect may be mediated by the normalization of neurotransmitter and corticosterone levels and the alleviation of oxidative stress, as well as the enhancement of the pi3k/akt/mtor-mediated bdnf/trkb pathway. |
2019-12-26 |
2023-08-13 |
mouse |
| Helein Plein, Michael Ber. The platelet as a peripheral marker in psychiatric illness. Human psychopharmacology. vol 16. issue 3. 2019-11-20. PMID:12404575. |
the use of the platelet intracellular calcium response to neurotransmitter stimulation as a state or trait marker in major depression, the specificity and selectivity of this response, and the possible use of the platelet as a peripheral marker in psychotic disorders such as schizophrenia, mania and psychotic depression are shown. |
2019-11-20 |
2023-08-12 |
Not clear |
| James M Stevenson, Jeffrey R Bisho. Genetic determinants of selective serotonin reuptake inhibitor related sexual dysfunction. Pharmacogenomics. vol 15. issue 14. 2019-11-20. PMID:25493571. |
candidate gene studies have identified associations between sexual dysfunction and altered ssri pharmacokinetics or to the neurotransmitter systems affected by depression and ssri treatment. |
2019-11-20 |
2023-08-13 |
Not clear |
| Stephen Hogg, Sereena Ansari, Qasim Masood, Mark Agius, Zoltan Rihme. Are SSRIs responsible for precipitating suicidal ideation in teenagers with 'subsyndromal' bipolar affective disorder who have been misdiagnosed with unipolar depression? Psychiatria Danubina. vol 28. issue Suppl-1. 2019-11-20. PMID:27663811. |
one reason for this suboptimal response is the markedly different neurotransmission involved in bipolar depression as compared to the neurotransmitter systems operated on by ssris. |
2019-11-20 |
2023-08-13 |
Not clear |
| Bernard J Carroll, John F Greden, Roger Haskett, Michael Feinberg, A Ariav Albala, F I R Martin, Robert T Rubin, Barbara Heath, Peter T Sharp, W L McLeod, M F McLeo. NEUROTRANSMITTER STUDIES OF NEUROENDOCRINE PATHOLOGY IN DEPRESSION. Acta psychiatrica Scandinavica. vol 61. issue S280. 2019-11-20. PMID:28678372. |
neurotransmitter studies of neuroendocrine pathology in depression. |
2019-11-20 |
2023-08-13 |
Not clear |
| Katsuya Sakimura, Tatsuya Maekawa, Kazuo Sasagawa, Yukihito Ishii, Shin-Ichi Kume, Takeshi Oht. Depression-related behavioural and neuroendocrine changes in the Spontaneously Diabetic Torii (SDT) fatty rat, an animal model of type 2 diabetes mellitus. Clinical and experimental pharmacology & physiology. 2019-11-20. PMID:29757463. |
the results of the present study suggest that the sdt fatty rat may be an appropriate model for diabetes with comorbid depression associated with neurotransmitter impairments and aberrant basal hpa hyperactivity. |
2019-11-20 |
2023-08-13 |
rat |