| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ronald S Duman, Gerard Sanacora, John H Krysta. Altered Connectivity in Depression: GABA and Glutamate Neurotransmitter Deficits and Reversal by Novel Treatments. Neuron. vol 102. issue 1. 2019-11-04. PMID:30946828. |
altered connectivity in depression: gaba and glutamate neurotransmitter deficits and reversal by novel treatments. |
2019-11-04 |
2023-08-13 |
Not clear |
| Xiong-Jun Mou, Hao Liu, Ning Lin, Xin Chen, Song-Lin Li. [Effects of Shugan Hewei Decoction and active substance fractions on behavior and neurotransmitter levels in hypothalamus of depression model rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 44. issue 15. 2019-10-21. PMID:31602893. |
[effects of shugan hewei decoction and active substance fractions on behavior and neurotransmitter levels in hypothalamus of depression model rats]. |
2019-10-21 |
2023-08-13 |
rat |
| Xiong-Jun Mou, Hao Liu, Ning Lin, Xin Chen, Song-Lin Li. [Effects of Shugan Hewei Decoction and active substance fractions on behavior and neurotransmitter levels in hypothalamus of depression model rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 44. issue 15. 2019-10-21. PMID:31602893. |
to investigate the effects of shugan hewei decoction and its active substance fractions on behavior and neurotransmitter levels in hypothalamus of depression model rats,and preliminarily explore its possible mechanism. |
2019-10-21 |
2023-08-13 |
rat |
| Yun-Sik Kim, David Michael O'Sullivan, Sang-Keun Shi. Can 24 weeks strength training reduce feelings of depression and increase neurotransmitter in elderly females? Experimental gerontology. vol 115. 2019-09-17. PMID:30453010. |
can 24 weeks strength training reduce feelings of depression and increase neurotransmitter in elderly females? |
2019-09-17 |
2023-08-13 |
Not clear |
| Yun-Sik Kim, David Michael O'Sullivan, Sang-Keun Shi. Can 24 weeks strength training reduce feelings of depression and increase neurotransmitter in elderly females? Experimental gerontology. vol 115. 2019-09-17. PMID:30453010. |
therefore, this study aimed to investigate the effects of 24 weeks of the growing stronger program on neurotransmitter and depression of older women. |
2019-09-17 |
2023-08-13 |
Not clear |
| Manami Yamashita, Shin-Ya Kawaguchi, Tetsuya Hori, Tomoyuki Takahash. Vesicular GABA Uptake Can Be Rate Limiting for Recovery of IPSCs from Synaptic Depression. Cell reports. vol 22. issue 12. 2019-09-16. PMID:29562170. |
bursts of presynaptic firings depress synaptic efficacy, mainly due to depletion of releasable vesicles, whereas recovery from strong depression is initiated by endocytic vesicle retrieval followed by refilling of vesicles with neurotransmitter. |
2019-09-16 |
2023-08-13 |
rat |
| Anna Haduch, Władysława Anna Danie. The engagement of brain cytochrome P450 in the metabolism of endogenous neuroactive substrates: a possible role in mental disorders. Drug metabolism reviews. vol 50. issue 4. 2019-06-14. PMID:30501426. |
cyp-mediated alternative pathways of dopamine and serotonin synthesis may have a significant role in the local production of these neurotransmitters in the brain regions where the disturbances of these neurotransmitter systems are observed in depression and schizophrenia. |
2019-06-14 |
2023-08-13 |
human |
| Jennifer L Payne, Jamie Maguir. Pathophysiological mechanisms implicated in postpartum depression. Frontiers in neuroendocrinology. vol 52. 2019-05-17. PMID:30552910. |
the evidence supporting a role for neuroendocrine changes, neuroinflammation, neurotransmitter alterations, circuit dysfunction, and the involvement of genetics and epigenetics in the pathophysiology of postpartum depression are discussed. |
2019-05-17 |
2023-08-13 |
Not clear |
| Hans-Gert Bernstein, Henrik Dobrowolny, Bernhard Bogerts, Gerburg Keilhoff, Johann Steine. The hypothalamus and neuropsychiatric disorders: psychiatry meets microscopy. Cell and tissue research. vol 375. issue 1. 2019-05-16. PMID:29767278. |
gross anatomical abnormalities (volume changes of the third ventricle, the hypothalamus, and its nuclei) and alterations at the cellular level (loss of neurons, increased or decreased expression of hypothalamic peptides such as oxytocin, vasopressin, corticotropin-releasing hormone, and other regulatory factors as well as of enzymes involved in neurotransmitter and neuropeptide metabolism) have been reported in schizophrenia and/or depression. |
2019-05-16 |
2023-08-13 |
Not clear |
| Zuotian Wu, Gaohua Wang, Yanyan Wei, Ling Xiao, Huiling Wan. PI3K/AKT/GSK3β/CRMP-2-mediated neuroplasticity in depression induced by stress. Neuroreport. vol 29. issue 15. 2019-04-18. PMID:30113922. |
the changes in neural plasticity, such as microtubule system of nerve scaffold, extension of axonal dendrites, regeneration of nerve junctions, disturbance of neurotransmitter synthesis, transmission and release, and abnormal synapses, cause abnormal transmission of information between nerve cells and cause symptoms of depression. |
2019-04-18 |
2023-08-13 |
Not clear |
| Marie Krøll Knudsen, Jamie Near, Anne Bastholm Blicher, Poul Videbech, Jakob Udby Bliche. Magnetic resonance (MR) spectroscopic measurement of γ-aminobutyric acid (GABA) in major depression before and after electroconvulsive therapy. Acta neuropsychiatrica. vol 31. issue 1. 2019-04-17. PMID:30079857. |
prior studies suggest that a dysregulation of the inhibitory neurotransmitter γ-aminobutyric acid (gaba) is involved in the pathophysiology of major depression. |
2019-04-17 |
2023-08-13 |
Not clear |
| Mary H Patton, Katherine E Padgett, Paige N McKeon, Shao-Gang Lu, Thomas W Abrams, Brian N Mathu. An Aplysia-like synaptic switch for rapid protection against ethanol-induced synaptic inhibition in a mammalian habit circuit. Neuropharmacology. vol 144. 2019-03-04. PMID:30321611. |
however, an exquisitely sensitive, activity-dependent homosynaptic mechanism that protects against the depression of neurotransmitter release in aplysia sensory neuron terminals has, to date, not been uncovered in other animals, including mammals. |
2019-03-04 |
2023-08-13 |
human |
| Mehrdad Salmasi, Alex Loebel, Stefan Glasauer, Martin Stemmle. Short-term synaptic depression can increase the rate of information transfer at a release site. PLoS computational biology. vol 15. issue 1. 2019-02-28. PMID:30601804. |
depending on the recent history of synaptic activation, many synapses depress the probability of releasing more neurotransmitter, which is known as synaptic depression. |
2019-02-28 |
2023-08-13 |
Not clear |
| Xuan Liu, Ge Jin, Bilian Fan, Yang Xing, Lei Wang, Min Wang, Yueming Yuan, Qiwen Zh. The impact of ALDH2 activation by Alda-1 on the expression of VEGF in the hippocampus of a rat model of post-MI depression. Neuroscience letters. vol 674. 2019-02-25. PMID:29574217. |
these behaviors were associated with an increase 5-ht and da neurotransmitter content, as well as an increase of vegf levels in the hippocampus of the post-mi depression rats. |
2019-02-25 |
2023-08-13 |
rat |
| E L Gibso. Tryptophan supplementation and serotonin function: genetic variations in behavioural effects. The Proceedings of the Nutrition Society. vol 77. issue 2. 2019-01-16. PMID:29368666. |
the neurotransmitter serotonin has a role in affective disorders such as depression and anxiety, as well as sleep, cognitive function and appetite. |
2019-01-16 |
2023-08-13 |
Not clear |
| b' Connie Sanchez, Aram El Khoury, Moustapha Hassan, Gregers Wegener, Aleksander A Math\\xc3\\xa. Sex-dependent behavior, neuropeptide profile and antidepressant response in rat model of depression. Behavioural brain research. vol 351. 2018-12-18. PMID:29857028.' |
understanding the link between depression and stress has been and remains a major focus area for development of animal models, but lines of research with a more mechanistic focus targeting deficiencies in neurotransmitter systems or dysfunctional neuronal circuitries and neuroinflammation are also pursued vigorously. |
2018-12-18 |
2023-08-13 |
rat |
| Wen-Jun Su, Zhi-Yong Cao, Chun-Lei Jian. [Inflammatory mechanism of depression and its new strategy for diagnosis and treatment]. Sheng li xue bao : [Acta physiologica Sinica]. vol 69. issue 5. 2018-08-29. PMID:29063119. |
at present, the exact pathophysiological mechanism of depression still remains unclear, but researchers across the globe put forward various hypotheses to interpret the possible access to this disease, including monoamine neurotransmitter disturbance, hypothalamic-pituitary-adrenal (hpa) axis dysfunction, lack of neurotrophic factors and excessive pro-inflammatory cytokines. |
2018-08-29 |
2023-08-13 |
Not clear |
| Ryan Rieder, Paul J Wisniewski, Brandon L Alderman, Sara C Campbel. Microbes and mental health: A review. Brain, behavior, and immunity. vol 66. 2018-06-06. PMID:28131791. |
the role of stress and stress-mediated changes in autonomic, neuroendocrine, immune, and neurotransmitter systems are examined, followed by a discussion of the role of the microbiota in novel gastrointestinal-based treatment options for the prevention and treatment of brain-based disorders such as anxiety and depression. |
2018-06-06 |
2023-08-13 |
human |
| Frédéric Doussau, Hartmut Schmidt, Kevin Dorgans, Antoine M Valera, Bernard Poulain, Philippe Isop. Frequency-dependent mobilization of heterogeneous pools of synaptic vesicles shapes presynaptic plasticity. eLife. vol 6. 2018-06-04. PMID:28990927. |
conversely, a second pool of synaptic vesicles that cannot be released by a single stimulus is recruited within milliseconds by high-frequency stimulation and support an ultrafast recovery of neurotransmitter release after low-frequency depression. |
2018-06-04 |
2023-08-13 |
mouse |
| Zhiqiang Xu, Xiaobo Guo, Yong Yang, Donovan Tucker, Yujiao Lu, Ning Xin, Gaocai Zhang, Lingli Yang, Jizhen Li, Xiangdong Du, Quanguang Zhang, Xingshun X. Low-Level Laser Irradiation Improves Depression-Like Behaviors in Mice. Molecular neurobiology. vol 54. issue 6. 2018-04-09. PMID:27379735. |
as a whole, these findings shed light on a novel strategy of transcranial lllt on depression improvement by ameliorating neurotransmitter abnormalities and promoting mitochondrial function in pfc. |
2018-04-09 |
2023-08-13 |
mouse |