| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fei Huang, Xiaojun W. Brain Neurotransmitter Modulation by Gut Microbiota in Anxiety and Depression. Frontiers in cell and developmental biology. vol 9. 2021-03-30. PMID:33777957. |
brain neurotransmitter modulation by gut microbiota in anxiety and depression. |
2021-03-30 |
2023-08-13 |
human |
| Fei Huang, Xiaojun W. Brain Neurotransmitter Modulation by Gut Microbiota in Anxiety and Depression. Frontiers in cell and developmental biology. vol 9. 2021-03-30. PMID:33777957. |
anxiety and depression are highly prevalent mental illnesses worldwide and have long been thought to be closely associated to neurotransmitter modulation. |
2021-03-30 |
2023-08-13 |
human |
| Fei Huang, Xiaojun W. Brain Neurotransmitter Modulation by Gut Microbiota in Anxiety and Depression. Frontiers in cell and developmental biology. vol 9. 2021-03-30. PMID:33777957. |
all the results strongly support that the brain neurotransmitter modulation by gut microbiota is indispensable to the physiopathology of anxiety and depression. |
2021-03-30 |
2023-08-13 |
human |
| Fei Huang, Xiaojun W. Brain Neurotransmitter Modulation by Gut Microbiota in Anxiety and Depression. Frontiers in cell and developmental biology. vol 9. 2021-03-30. PMID:33777957. |
overall, the gut microbiota provides a novel way to alter neurotransmitter modulation in the brain and treat gut-brain axis diseases, such as anxiety and depression. |
2021-03-30 |
2023-08-13 |
human |
| Brendan D Hare, Ronald S Duma. Prefrontal cortex circuits in depression and anxiety: contribution of discrete neuronal populations and target regions. Molecular psychiatry. vol 25. issue 11. 2021-03-15. PMID:32086434. |
this work has resulted in a paradigm shift away from dysregulation of single neurotransmitter systems in depression towards circuit level abnormalities impacting function across multiple brain regions and neurotransmitter systems. |
2021-03-15 |
2023-08-13 |
Not clear |
| Tao Yang, Xubo Wang, Lei Liu, Hanwen Chen, Na Wan. Ginkgolide-Platinum(II) Complex GPt(II) Exhibits Therapeutic Effect on Depression in Mice via Upregulation of DA and 5-HT Neurotransmitters. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-02-02. PMID:32484164. |
conclusions gpt(ii) treatment significantly relieved characteristics of depression in the mice through upregulation of neurotransmitter, neuropeptide, and hsp70 expression. |
2021-02-02 |
2023-08-13 |
mouse |
| Sabrina Duranti, Lorena Ruiz, Gabriele Andrea Lugli, Héctor Tames, Christian Milani, Leonardo Mancabelli, Walter Mancino, Giulia Longhi, Luca Carnevali, Andrea Sgoifo, Abelardo Margolles, Marco Ventura, Patricia Ruas-Madiedo, Francesca Turron. Bifidobacterium adolescentis as a key member of the human gut microbiota in the production of GABA. Scientific reports. vol 10. issue 1. 2021-01-07. PMID:32839473. |
gamma aminobutyric acid (gaba) is the principal inhibitory neurotransmitter playing a key role in anxiety and depression disorders in mammals. |
2021-01-07 |
2023-08-13 |
human |
| Ioana R Ili. Neurotransmitter, neuropeptide and gut peptide profile in PCOS-pathways contributing to the pathophysiology, food intake and psychiatric manifestations of PCOS. Advances in clinical chemistry. vol 96. 2021-01-01. PMID:32362321. |
further, the dysregulated neurotransmitter and neuropeptide profile in pcos could also be the reason for low self-esteem, anxiety, mood swings and depression or obesity, features closely associated with pcos women. |
2021-01-01 |
2023-08-13 |
Not clear |
| Zhifei Li, Zhaoxia Li, Xiaoman Lv, Zhaofu Li, Lei Xiong, Xintian Hu, Dongdong Qi. Intracerebroventricular Administration of Interferon-Alpha Induced Depressive-Like Behaviors and Neurotransmitter Changes in Rhesus Monkeys. Frontiers in neuroscience. vol 14. 2020-12-18. PMID:33328856. |
monoamine neurotransmitter systems have been found playing important roles in peripheral ifn-α-induced depression, but how peripheral ifn-α accesses the central nervous system and contributes to the development of depression is poorly known. |
2020-12-18 |
2023-08-13 |
monkey |
| Zhifei Li, Zhaoxia Li, Xiaoman Lv, Zhaofu Li, Lei Xiong, Xintian Hu, Dongdong Qi. Intracerebroventricular Administration of Interferon-Alpha Induced Depressive-Like Behaviors and Neurotransmitter Changes in Rhesus Monkeys. Frontiers in neuroscience. vol 14. 2020-12-18. PMID:33328856. |
administration of ifn-α (5 days/week for 6 weeks), to observe the induced depressive-like behaviors and to explore the contributions of monoamine neurotransmitter systems in the development of depression. |
2020-12-18 |
2023-08-13 |
monkey |
| Nurul Uyun Abdul Aziz, Samaila Musa Chiroma, Mohamad Aris Mohd Moklas, Mohd Ilham Adenan, Amin Ismail, Mohamad Taufik Hidayat Baharuldi. Antidepressant-Like Properties of Fish Oil on Postpartum Depression-Like Rats Model: Involvement of Serotonergic System. Brain sciences. vol 10. issue 10. 2020-11-03. PMID:33066310. |
pathophysiology of postpartum depression (ppd) has been associated with many factors, such as neuroendocrine, neuroinflammation and neurotransmitter changes. |
2020-11-03 |
2023-08-13 |
rat |
| Hiroshi Tsutsumi, Kosei Yonemitsu, Ako Sasao, Yuki Ohtsu, Shota Furukawa, Yoko Nishitan. Cerebrospinal fluid neurotransmitter levels and central nervous system depression in a rat drug overdose model. Toxicology mechanisms and methods. vol 30. issue 2. 2020-10-19. PMID:31550965. |
cerebrospinal fluid neurotransmitter levels and central nervous system depression in a rat drug overdose model. |
2020-10-19 |
2023-08-13 |
rat |
| Victor B Feni. Contribution of Neurochemical Inputs to the Decrease of Motoneuron Excitability During Non-REM and REM Sleep: A Systematic Review. Frontiers in neurology. vol 9. 2020-10-01. PMID:30108546. |
the outcomes of this analysis highlight the differences in the neurotransmitter mechanisms of sleep-related motoneuron depression between different motoneuronal pools and demonstrate the consistency of these mechanisms for hypoglossal motoneurons among various animal models. |
2020-10-01 |
2023-08-13 |
Not clear |
| Rachel A Saylor, Melinda Hersey, Alyssa West, Anna Marie Buchanan, Shane N Berger, H Frederik Nijhout, Michael C Reed, Janet Best, Parastoo Hashem. Frontiers in neuroscience. vol 13. 2020-10-01. PMID:31110471. |
the biology of depression is not well understood, but experts agree that a key neurotransmitter of interest is serotonin. |
2020-10-01 |
2023-08-13 |
Not clear |
| Deepthi Joseph, Shabareesh Pidathala, Aditya Kumar Mallela, Aravind Penmats. Structure and Gating Dynamics of Na Frontiers in molecular biosciences. vol 6. 2020-10-01. PMID:31555663. |
drug-induced changes in the synaptic neurotransmitter levels can be used to treat depression or neuropathic pain whereas in some instances prolonged usage can lead to habituation. |
2020-10-01 |
2023-08-13 |
Not clear |
| Lígia Castanheira, Carlos Silva, Elie Cheniaux, Diogo Telles-Correi. Neuroimaging Correlates of Depression-Implications to Clinical Practice. Frontiers in psychiatry. vol 10. 2020-09-30. PMID:31632306. |
the growth of the literature about neuroimaging of major depressive disorder (mdd) over the last several decades has contributed to the progress in recognizing precise brain areas, networks, and neurotransmitter processes related to depression. |
2020-09-30 |
2023-08-13 |
Not clear |
| Xiaojun Shao, Gang Zh. Associations Among Monoamine Neurotransmitter Pathways, Personality Traits, and Major Depressive Disorder. Frontiers in psychiatry. vol 11. 2020-09-28. PMID:32477180. |
monoamine neurotransmitter system dysfunction and specific personality traits are independent risk factors for depression and suicide. |
2020-09-28 |
2023-08-13 |
Not clear |
| Nefize Yalin, Allan H Youn. Pharmacological Treatment of Bipolar Depression: What are the Current and Emerging Options? Neuropsychiatric disease and treatment. vol 16. 2020-09-28. PMID:32606699. |
in addition, novel agents targeting alternative neurotransmitter pathways and inflammatory processes (such as ketamine and n-acetyl cysteine) are emerging as promising potential options for the treatment of bipolar depression in the future. |
2020-09-28 |
2023-08-13 |
Not clear |
| Patrícia Patrício, António Mateus-Pinheiro, Nuno Dinis Alves, Mónica Morais, Ana João Rodrigues, João Miguel Bessa, Nuno Sousa, Luísa Pint. miR-409 and miR-411 Modulation in the Adult Brain of a Rat Model of Depression and After Fluoxetine Treatment. Frontiers in behavioral neuroscience. vol 14. 2020-09-28. PMID:32848656. |
additional bioinformatic analyses revealed target genes and pathways of these mirnas related to neurotransmitter signaling and neuroplasticity functions; an implication of the two mirnas in the regulation of the cellular and molecular changes observed in these brain regions in depression is worth further examination. |
2020-09-28 |
2023-08-13 |
rat |
| Rong Yang, Meng-Qi Zhang, Ying Xue, Rui Yang, Mi-Mi Tan. Dietary of n-3 polyunsaturated fatty acids influence neurotransmitter systems of rats exposed to unpredictable chronic mild stress. Behavioural brain research. vol 376. 2020-09-03. PMID:31445977. |
altered neurotransmitter turnover rates and between-metabolite ratios in brain may be better predictors in depression and antidepressant treatment compared with monoamine neurotransmitters. |
2020-09-03 |
2023-08-13 |
rat |