| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zaiquan Dong, Qinglian Xie, Feiyu Xu, Xiaoling Shen, Yanni Hao, Jin Li, Haizhen Xu, Qiang Peng, Weihong Kuan. Neferine alleviates chronic stress-induced depression by regulating monoamine neurotransmitter secretion and gut microbiota structure. Frontiers in pharmacology. vol 13. 2022-09-19. PMID:36120376. |
neferine alleviates chronic stress-induced depression by regulating monoamine neurotransmitter secretion and gut microbiota structure. |
2022-09-19 |
2023-08-14 |
mouse |
| Mohammad Hendra Setia Lesmana, Nguyen Quoc Khanh Le, Wei-Che Chiu, Kuo-Hsuan Chung, Chih-Yang Wang, Lalu Muhammad Irham, Min-Huey Chun. Genomic-Analysis-Oriented Drug Repurposing in the Search for Novel Antidepressants. Biomedicines. vol 10. issue 8. 2022-08-26. PMID:36009493. |
from inadequate prior antidepressants that targeted monoamine neurotransmitter systems emerged the discovery of alternative drugs for depression. |
2022-08-26 |
2023-08-14 |
Not clear |
| Hanchuang Zhu, Pan Jia, Xin Wang, Ying Tian, Caiyun Liu, Xiwei Li, Kun Wang, Ping Li, Baocun Zhu, Bo Tan. In Situ Observation of Lysosomal Hypobromous Acid Fluctuations in the Brain of Mice with Depression Phenotypes by Two-Photon Fluorescence Imaging. Analytical chemistry. 2022-08-18. PMID:35979623. |
excessive oxidative stress is the main cause of neurotransmitter metabolism disorder in the brain with depression. |
2022-08-18 |
2023-08-14 |
mouse |
| Ziqian Cheng, Jingyun Su, Kai Zhang, Huiyi Jiang, Bingjin L. Epigenetic Mechanism of Early Life Stress-Induced Depression: Focus on the Neurotransmitter Systems. Frontiers in cell and developmental biology. vol 10. 2022-07-22. PMID:35865627. |
epigenetic mechanism of early life stress-induced depression: focus on the neurotransmitter systems. |
2022-07-22 |
2023-08-14 |
Not clear |
| Ziqian Cheng, Jingyun Su, Kai Zhang, Huiyi Jiang, Bingjin L. Epigenetic Mechanism of Early Life Stress-Induced Depression: Focus on the Neurotransmitter Systems. Frontiers in cell and developmental biology. vol 10. 2022-07-22. PMID:35865627. |
in this article, we review the effects of epigenetic modifications on the neurotransmitter systems in depression-like outcomes produced by different types of els in recent years, aiming to provide new therapeutic targets for patients who suffer from depression. |
2022-07-22 |
2023-08-14 |
Not clear |
| Hammad Ullah, Ayesha Khan, Kannan R R Rengasamy, Alessandro Di Minno, Roberto Sacchi, Maria Dagli. The Efficacy of S-Adenosyl Methionine and Probiotic Supplementation on Depression: A Synergistic Approach. Nutrients. vol 14. issue 13. 2022-07-09. PMID:35807931. |
gut dysbiosis is one of the risk factors in depression by inducing systemic inflammation accompanied by an imbalance in neurotransmitter production. |
2022-07-09 |
2023-08-14 |
Not clear |
| Li-Min Mao, Nirav Mathur, John Q Wan. Downregulation of surface AMPA receptor expression in the striatum following prolonged social isolation, a role of mGlu5 receptors. IBRO neuroscience reports. vol 13. 2022-06-17. PMID:35711245. |
multiple neurotransmitter systems are believed to be implicated in depression. |
2022-06-17 |
2023-08-14 |
rat |
| Jing Ren, Chenyang Li, Songren Wei, Yanjun He, Peng Huang, Jiangping X. Identifying Antidepressant Effects of Brain-Derived Neurotrophic Factor and IDO1 in the Mouse Model Based on RNA-Seq Data. Frontiers in genetics. vol 13. 2022-06-17. PMID:35711916. |
the neurotransmitter hypothesis of depression at the transcriptomic level can be tested using bdnf- and ido1-knockout mouse models and rna-seq. |
2022-06-17 |
2023-08-14 |
mouse |
| Yizhou Xin, Ying Zhang, Xiaoli Zhan. Antidepressant Effect of Water Extract of Royal Sun Medicinal Mushroom, Agaricus brasiliensis (Agaricomycetes), in Mice Exposed to Chronic Unpredictable Mild Stress. International journal of medicinal mushrooms. vol 24. issue 4. 2022-06-13. PMID:35695597. |
collectively, these results suggest that awe possesses good antidepressant activity, and these effects may be mediated by enhancing monoamine neurotransmitter content in the brain or antioxidant capacity to improve depression. |
2022-06-13 |
2023-08-14 |
mouse |
| Olamide Wilson Fasakin, Ganiyu Oboh, Ayokunle Olubode Ademosun, Akeem O Lawa. The modulatory effects of alkaloid extracts of Cannabis sativa, Datura stramonium, Nicotiana tabacum and male Carica papaya on neurotransmitter, neurotrophic and neuroinflammatory systems linked to anxiety and depression. Inflammopharmacology. 2022-06-06. PMID:35665872. |
the modulatory effects of alkaloid extracts of cannabis sativa, datura stramonium, nicotiana tabacum and male carica papaya on neurotransmitter, neurotrophic and neuroinflammatory systems linked to anxiety and depression. |
2022-06-06 |
2023-08-14 |
rat |
| Olamide Wilson Fasakin, Ganiyu Oboh, Ayokunle Olubode Ademosun, Akeem O Lawa. The modulatory effects of alkaloid extracts of Cannabis sativa, Datura stramonium, Nicotiana tabacum and male Carica papaya on neurotransmitter, neurotrophic and neuroinflammatory systems linked to anxiety and depression. Inflammopharmacology. 2022-06-06. PMID:35665872. |
this study investigated the modulatory effects of alkaloid extracts of cannabis sativa (csae), datura stramonium (dsae), nicotiana tabacum (ntae) and male carica papaya (cmae) on neurotransmitter, neurotrophic and neuro-inflammatory systems linked to anxiety and depression. |
2022-06-06 |
2023-08-14 |
rat |
| Yan Li, Zhi Chen, Jianting Zhao, Heming Yu, Xiangyu Chen, Yong He, Yu Tian, Yue Wang, Chong Chen, Ke Cheng, Peng Xi. Neurotransmitter and Related Metabolic Profiling in the Nucleus Accumbens of Chronic Unpredictable Mild Stress-Induced Anhedonia-Like Rats. Frontiers in behavioral neuroscience. vol 16. 2022-05-16. PMID:35571281. |
the neurotransmitter deficiency hypothesis has been the crux of much research on the treatment of depression. |
2022-05-16 |
2023-08-13 |
rat |
| Haider Sarwar, Shafiya Imtiaz Rafiqi, Showkat Ahmad, Sruthi Jinna, Sawleha Arshi Khan, Tamanna Karim, Omar Qureshi, Zeeshan A Zahid, Jon D Elhai, Jason C Levine, Shazia J Naqvi, Juan C Jaume, Shahnawaz Ima. Hyperinsulinemia Associated Depression. Clinical medicine insights. Endocrinology and diabetes. vol 15. 2022-05-02. PMID:35494421. |
increased inflammatory cytokines have also been shown to disrupt neurotransmitter metabolism and synaptic plasticity which play a role in the development of depression via inhibiting serotonin, dopamine, melatonin, and glutamate signaling. |
2022-05-02 |
2023-08-13 |
Not clear |
| Shefali Chaudhary, Simon Zhornitsky, Herta H Chao, Christopher H van Dyck, Chiang-Shan R L. Emotion Processing Dysfunction in Alzheimer's Disease: An Overview of Behavioral Findings, Systems Neural Correlates, and Underlying Neural Biology. American journal of Alzheimer's disease and other dementias. vol 37. 2022-03-31. PMID:35357236. |
finally, the reviewed studies implicating major neurotransmitter systems in anxiety and depression in ad supported altered cholinergic and noradrenergic signaling in ad emotional disorders. |
2022-03-31 |
2023-08-13 |
Not clear |
| Sharon Cabanu, Fuencisla Pilar-Cuéllar, Paula Zubakina, Eva Florensa-Zanuy, Júlia Senserrich, Adrian Newman-Tancredi, Albert Adel. Molecular Signaling Mechanisms for the Antidepressant Effects of NLX-101, a Selective Cortical 5-HT Pharmaceuticals (Basel, Switzerland). vol 15. issue 3. 2022-03-26. PMID:35337135. |
molecular signaling mechanisms for the antidepressant effects of nlx-101, a selective cortical 5-ht depression is the most prevalent of the mental illnesses and serotonin (5-hydroxytryptamine, 5-ht) is considered to be the major neurotransmitter involved in its etiology and treatment. |
2022-03-26 |
2023-08-13 |
Not clear |
| Yingying Wang, Xueman Chen, Qiaoyu Chen, Ning Zhou, Xin Wang, Alei Zhang, Kequan Chen, Pingkai Ouyan. Construction of cell factory capable of efficiently converting L-tryptophan into 5-hydroxytryptamine. Microbial cell factories. vol 21. issue 1. 2022-03-25. PMID:35331215. |
among, 5-ht is an inhibitory neurotransmitter with proven benefits for treating the symptoms of depression. |
2022-03-25 |
2023-08-13 |
Not clear |
| Bing Jiang, Ruo-Ming Wu, Hai-Dong Li, Kun Li, Hui Li, Wen-Zhen Dang, Gui-Ze Feng, Wei-Lian Bao, Guan Ye, Xiao-Yan She. Yixin Ningshen Tablet Alleviates Comorbidity of Myocardial Infarction and Depression by Enhancing Myocardial Energy Metabolism and Increasing Availability of Monoamine Neurotransmitter. Chinese journal of integrative medicine. 2022-03-23. PMID:35319073. |
yixin ningshen tablet alleviates comorbidity of myocardial infarction and depression by enhancing myocardial energy metabolism and increasing availability of monoamine neurotransmitter. |
2022-03-23 |
2023-08-13 |
rat |
| Gita Kholghi, Shirin Arjmandi-Rad, Mohammad-Reza Zarrindast, Salar Vasegh. St. John's wort (Hypericum perforatum) and depression: what happens to the neurotransmitter systems? Naunyn-Schmiedeberg's archives of pharmacology. 2022-03-16. PMID:35294606. |
st. john's wort (hypericum perforatum) and depression: what happens to the neurotransmitter systems? |
2022-03-16 |
2023-08-13 |
Not clear |
| Shaoqiang Han, Ruiping Zheng, Shuying Li, Bingqian Zhou, Yu Jiang, Caihong Wang, Yarui Wei, Jianyue Pang, Hengfen Li, Yong Zhang, Yuan Chen, Jingliang Chen. Integrative Functional, Molecular, and Transcriptomic Analyses of Altered Intrinsic Timescale Gradient in Depression. Frontiers in neuroscience. vol 16. 2022-03-07. PMID:35250462. |
these findings revealed atypical timescale gradient in depression and built a link between neuroimaging, transcriptome, and neurotransmitter information, facilitating an integrative understanding of depression. |
2022-03-07 |
2023-08-13 |
Not clear |
| Chulpan R Gafurova, Andrei N Tsentsevitsky, Alexey M Petro. Frequency-Dependent Engagement of Synaptic Vesicle Pools in the Mice Motor Nerve Terminals. Cellular and molecular neurobiology. 2022-02-03. PMID:35113291. |
in addition, depression of neurotransmitter release induced by 20 hz stimulation occurred independent on previous episode of 10 hz activity. |
2022-02-03 |
2023-08-13 |
mouse |