| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chulpan R Gafurova, Andrei N Tsentsevitsky, Alexey M Petro. Frequency-Dependent Engagement of Synaptic Vesicle Pools in the Mice Motor Nerve Terminals. Cellular and molecular neurobiology. 2022-02-03. PMID:35113291. |
in addition, depression of neurotransmitter release induced by 20 hz stimulation occurred independent on previous episode of 10 hz activity. |
2022-02-03 |
2023-08-13 |
mouse |
| Aparna Ann Mathew, Rajitha Panonnumma. Cortical spreading depression: culprits and mechanisms. Experimental brain research. 2022-01-22. PMID:35064796. |
cortical spreading depression or csd is an electrophysiological phenomenon affecting various perspectives of brain physiology such as ionic balance, neurotransmitter level, and blood flow in the brain. |
2022-01-22 |
2023-08-13 |
Not clear |
| Yuvaraj Balan, Archana Gaur, Varatharajan Sakthivadivel, Bhushan Kamble, Raja Sundaramurth. Is the Gut Microbiota a Neglected Aspect of Gut and Brain Disorders? Cureus. vol 13. issue 11. 2021-12-23. PMID:34938619. |
in brain disorders, gut dysbiosis is involved in neuropsychiatric manifestations, including autism spectrum disorder, anxiety, and depression by interfering with neurotransmitter homeostasis, and neurodegenerative diseases, such as alzheimer's disease and parkinson's disease by releasing abnormal metabolites from the gut. |
2021-12-23 |
2023-08-13 |
human |
| Baiping Liu, Yongping Zhang, Zhiyou Yang, Meijun Liu, Cai Zhang, Yuntao Zhao, Cai Son. ω-3 DPA Protected Neurons from Neuroinflammation by Balancing Microglia M1/M2 Polarizations through Inhibiting NF-κB/MAPK p38 Signaling and Activating Neuron-BDNF-PI3K/AKT Pathways. Marine drugs. vol 19. issue 11. 2021-11-28. PMID:34822458. |
microglia m1 phenotype causes hpa axis hyperactivity, neurotransmitter dysfunction, and production of proinflammatory mediators and oxidants, which may contribute to the etiology of depression and neurodegenerative diseases. |
2021-11-28 |
2023-08-13 |
Not clear |
| Hai-Long Yang, Meng-Meng Li, Man-Fei Zhou, Huai-Sha Xu, Fei Huan, Na Liu, Rong Gao, Jun Wang, Ning Zhang, Lei Jian. Links Between Gut Dysbiosis and Neurotransmitter Disturbance in Chronic Restraint Stress-Induced Depressive Behaviours: the Role of Inflammation. Inflammation. vol 44. issue 6. 2021-11-26. PMID:34657991. |
the present study aimed to investigate the neuroinflammatory reactions in chronic restraint stress (crs)-induced depression and to delineate the potential links between the gut microbiota and neurotransmitter metabolism. |
2021-11-26 |
2023-08-13 |
mouse |
| Hai-Long Yang, Meng-Meng Li, Man-Fei Zhou, Huai-Sha Xu, Fei Huan, Na Liu, Rong Gao, Jun Wang, Ning Zhang, Lei Jian. Links Between Gut Dysbiosis and Neurotransmitter Disturbance in Chronic Restraint Stress-Induced Depressive Behaviours: the Role of Inflammation. Inflammation. vol 44. issue 6. 2021-11-26. PMID:34657991. |
taken together, the results suggest that inflammation is involved in microbiota dysbiosis and the disturbance of neurotransmitter metabolism in crs-induced depressive changes, and the delineation of the potential links between the microbiota and neurotransmitter metabolism will provide novel strategies for depression treatment. |
2021-11-26 |
2023-08-13 |
mouse |
| Syeda Madiha, Zehra Batool, Saiqa Tabassum, Laraib Liaquat, Sadia Sadir, Sidrah Shahzad, Fizza Naqvi, Sadia Saleem, Sarwat Yousuf, Amber Nawaz, Saara Ahmad, Irfan Sajid, Asia Afzal, Saida Haide. Quercetin exhibits potent antioxidant activity, restores motor and non-motor deficits induced by rotenone toxicity. PloS one. vol 16. issue 11. 2021-11-18. PMID:34767546. |
results showed that supplementation of quercetin significantly (p<0.01) restored rotenone-induced motor and non-motor deficits (depression and cognitive impairments), enhanced antioxidant enzyme activities (p<0.01), and attenuated neurotransmitter alterations (p<0.01). |
2021-11-18 |
2023-08-13 |
rat |
| F Leblhuber, S Geisler, D Ehrlich, K Steiner, G Reibnegger, Dietmar Fuchs, K Kur. Repetitive transcranial magnetic stimulation in the treatment of resistant depression: changes of specific neurotransmitter precursor amino acids. Journal of neural transmission (Vienna, Austria : 1996). vol 128. issue 8. 2021-11-16. PMID:34244826. |
repetitive transcranial magnetic stimulation in the treatment of resistant depression: changes of specific neurotransmitter precursor amino acids. |
2021-11-16 |
2023-08-13 |
Not clear |
| F Leblhuber, S Geisler, D Ehrlich, K Steiner, G Reibnegger, Dietmar Fuchs, K Kur. Repetitive transcranial magnetic stimulation in the treatment of resistant depression: changes of specific neurotransmitter precursor amino acids. Journal of neural transmission (Vienna, Austria : 1996). vol 128. issue 8. 2021-11-16. PMID:34244826. |
in this interventional study safety, symptom development and changes of serum concentrations of neurotransmitter precursor amino acids, of immune activation and inflammation markers, of brain-derived neurotrophic factor (bdnf), nitrite as well as of salivary amylase were measured before and after a frontal polar cortex stimulation using rtms as add-on treatment in 38 patients with treatment-resistant depression. |
2021-11-16 |
2023-08-13 |
Not clear |
| Anastasios P Makris, Minois Karianaki, Konstantinos I Tsamis, Stavroula A Pascho. The role of the gut-brain axis in depression: endocrine, neural, and immune pathways. Hormones (Athens, Greece). vol 20. issue 1. 2021-10-28. PMID:32827123. |
previously seen as a disease pertaining solely to the central nervous system, depression is now perceived as a multifactorial condition that extends beyond neurotransmitter depletion. |
2021-10-28 |
2023-08-13 |
Not clear |
| Harry W M Steinbusch, Mohammad Amin Dolatkhah, David A Hopkin. Anatomical and neurochemical organization of the serotonergic system in the mammalian brain and in particular the involvement of the dorsal raphe nucleus in relation to neurological diseases. Progress in brain research. vol 261. 2021-10-22. PMID:33785137. |
this review describes the morphology, ascending projections and the complex neurotransmitter nature of the drn, stressing its role as a key research target into the neural bases of depression. |
2021-10-22 |
2023-08-13 |
Not clear |
| Jenny Slatman, Inge van de Ve. Gut feelings: depression as an embodied and affective phenomenon in Houellebecq's Medical humanities. vol 47. issue 3. 2021-10-15. PMID:32788195. |
gut feelings: depression as an embodied and affective phenomenon in houellebecq's current debates about the possible causes of depression reinforce the age-old body-mind dualism: while some claim that depression is caused by psychological or societal stress, others underline that it results from a shortage of the neurotransmitter serotonin in the central nervous system. |
2021-10-15 |
2023-08-13 |
Not clear |
| Martin Nørgaard, Vincent Beliveau, Melanie Ganz, Claus Svarer, Lars H Pinborg, Sune H Keller, Peter S Jensen, Douglas N Greve, Gitte M Knudse. A high-resolution in vivo atlas of the human brain's benzodiazepine binding site of GABA NeuroImage. vol 232. 2021-10-14. PMID:33610745. |
a high-resolution in vivo atlas of the human brain's benzodiazepine binding site of gaba gamma-aminobutyric acid (gaba) is the main inhibitory neurotransmitter in the human brain and plays a key role in several brain functions and neuropsychiatric disorders such as anxiety, epilepsy, and depression. |
2021-10-14 |
2023-08-13 |
human |
| Jonas Persson, Anders Wall, Jan Weis, Malin Gingnell, Gunnar Antoni, Mark Lubberink, Robert Bodé. Inhibitory and excitatory neurotransmitter systems in depressed and healthy: A positron emission tomography and magnetic resonance spectroscopy study. Psychiatry research. Neuroimaging. vol 315. 2021-09-27. PMID:34246046. |
the gamma-aminobutyric acid (gaba) and glutamate (glu) neurotransmitter systems are implicated in depression. |
2021-09-27 |
2023-08-13 |
Not clear |
| Katharina Hüfner, Johannes M Giesinger, Johanna M Gostner, Jonas Egeter, Pia Koudouovoh-Tripp, Theresa Vill, Dietmar Fuchs, Barbara Sperner-Unterwege. Neurotransmitter Precursor Amino Acid Ratios Show Differential, Inverse Correlations with Depression Severity in the Low and High Depression Score Range. International journal of tryptophan research : IJTR. vol 14. 2021-09-07. PMID:34483668. |
neurotransmitter precursor amino acid ratios show differential, inverse correlations with depression severity in the low and high depression score range. |
2021-09-07 |
2023-08-13 |
Not clear |
| Katharina Hüfner, Johannes M Giesinger, Johanna M Gostner, Jonas Egeter, Pia Koudouovoh-Tripp, Theresa Vill, Dietmar Fuchs, Barbara Sperner-Unterwege. Neurotransmitter Precursor Amino Acid Ratios Show Differential, Inverse Correlations with Depression Severity in the Low and High Depression Score Range. International journal of tryptophan research : IJTR. vol 14. 2021-09-07. PMID:34483668. |
the current prospective longitudinal study was designed to evaluate the effect of acute mental stress on neurotransmitter precursor amino acid levels in individuals with depression at 2 time points. |
2021-09-07 |
2023-08-13 |
Not clear |
| Juncai Pu, Yiyun Liu, Siwen Gui, Lu Tian, Yue Yu, Xuemian Song, Xiaogang Zhong, Xiaopeng Chen, Weiyi Chen, Peng Zheng, Hanping Zhang, Xue Gong, Lanxiang Liu, Jing Wu, Haiyang Wang, Peng Xi. Metabolomic changes in animal models of depression: a systematic analysis. Molecular psychiatry. 2021-09-02. PMID:34471249. |
these findings suggested that metabolomic changes in depression models are characterized by decreased neurotransmitter and increased kynurenine metabolite levels in the brain, decreased amino acid and increased corticosterone levels in blood, and imbalanced energy metabolism and microbial metabolites in urine. |
2021-09-02 |
2023-08-13 |
Not clear |
| Justin D Tubbs, Jiahong Ding, Larry Baum, Pak C Sha. Systemic neuro-dysregulation in depression: Evidence from genome-wide association. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 39. 2021-08-26. PMID:32896454. |
first, we offer a brief review of two major biological systems with strong evidence for involvement in depression pathology: neurotransmitter systems and the stress response. |
2021-08-26 |
2023-08-13 |
Not clear |
| Sharon A Smith, Paula D Trotter, Francis P McGlone, Susannah C Walke. Effects of Acute Tryptophan Depletion on Human Taste Perception. Chemical senses. vol 46. 2021-08-26. PMID:33277648. |
serotonin is a key neurotransmitter implicated in the etiology of anxiety and depression; systemic and peripheral manipulations of serotonin signaling have previously been shown to modulate taste detection. |
2021-08-26 |
2023-08-13 |
human |
| Ning Liu, Shiqiang Sun, Pengjie Wang, Yanan Sun, Qingjuan Hu, Xiaoyu Wan. The Mechanism of Secretion and Metabolism of Gut-Derived 5-Hydroxytryptamine. International journal of molecular sciences. vol 22. issue 15. 2021-08-25. PMID:34360695. |
apart from being an important neurotransmitter and a paracrine signaling molecule in the gut, gut-derived 5-ht was also shown to exert other biological functions (in autism and depression) far beyond the gut. |
2021-08-25 |
2023-08-13 |
Not clear |