| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shun Hao, Wantong Shi, Weiqi Liu, Qi-Yu Chen, Min Zhu. Multiple modulatory roles of serotonin in chronic pain and injury-related anxiety. Frontiers in synaptic neuroscience. vol 15. 2023-05-05. PMID:37143481. |
serotonin (5-ht) in the central nervous system (cns) has been recognized as an important neurotransmitter and neuromodulator which regulates various physiological functions, such as pain sensation, cognition, and emotions-especially anxiety and depression. |
2023-05-05 |
2023-08-14 |
Not clear |
| Zhongqi Shen, Meng Yu, Zhenfei Don. Research Progress on the Pharmacodynamic Mechanisms of Sini Powder against Depression from the Perspective of the Central Nervous System. Medicina (Kaunas, Lithuania). vol 59. issue 4. 2023-04-28. PMID:37109699. |
the pathological causes of depression are associated with neuronal atrophy, synaptic loss, and neurotransmitter activity decline in the central nervous system (cns) resulting from injuries, such as inflammatory responses. |
2023-04-28 |
2023-08-14 |
Not clear |
| Irina Kudryashov. Presynaptic Plasticity Is Associated with Actin Polymerization. Biochemistry. Biokhimiia. vol 88. issue 3. 2023-04-19. PMID:37076285. |
we conclude that in addition to the increase in the neurotransmitter release probability, jasplakinolide induced other actin polymerization-dependent mechanisms, including those involved in the paired-pulse depression. |
2023-04-19 |
2023-08-14 |
rat |
| Yuping Han, Simeng Gu, Yumeng Li, Xin Qian, Fushun Wang, Jason H Huan. Neuroendocrine pathogenesis of perimenopausal depression. Frontiers in psychiatry. vol 14. 2023-04-17. PMID:37065890. |
by consulting the relevant literature in recent years, this paper elaborates the neuroendocrine mechanism of perimenopausal depression from the aspects of epigenetic changes, monoamine neurotransmitter and receptor hypothesis, glial cell-induced neuroinflammation, estrogen receptor, interaction between hpa axis and hpg axis, and micro-organism-brain gut axis. |
2023-04-17 |
2023-08-14 |
Not clear |
| Yusuf Oloruntoyin Ayipo, Iqrar Ahmad, Chien Fung Chong, Nurul Amira Zainurin, Sani Yahaya Najib, Harun Patel, Mohd Nizam Mord. Carbazole derivatives as promising competitive and allosteric inhibitors of human serotonin transporter: computational pharmacology. Journal of biomolecular structure & dynamics. 2023-04-06. PMID:37021485. |
the human serotonin transporters (hserts) are neurotransmitter sodium symporters of the aminergic g protein-coupled receptors, regulating the synaptic serotonin and neuropharmacological processes related to neuropsychiatric disorders, notably, depression. |
2023-04-06 |
2023-08-14 |
human |
| Giuseppe Barbat. Is REM Density a Measure of Arousal during Sleep? Brain sciences. vol 13. issue 3. 2023-03-29. PMID:36979188. |
disfunction of the neurotransmitter systems involved in arousal mechanisms and wake/sleep control might underlie the altered rem density described in depression. |
2023-03-29 |
2023-08-14 |
Not clear |
| Punya Sachdeva, Seongmin Ji, Shampa Ghosh, Soumya Ghosh, Manchala Raghunath, Hyunjin Kim, Rakesh Bhaskar, Jitendra Kumar Sinha, Sung Soo Ha. Plausible Role of Stem Cell Types for Treating and Understanding the Pathophysiology of Depression. Pharmaceutics. vol 15. issue 3. 2023-03-29. PMID:36986674. |
antidepressants manage clinical depression and function by modulating the serotonin, norepinephrine, and dopamine neurotransmitter levels in the brain. |
2023-03-29 |
2023-08-14 |
Not clear |
| Weiming Sun, Xizhen Kang, Xiangli Dong, Zijian Zeng, Qing Zou, Meixiang Su, Ke Zhang, Guanxiu Liu, Guohua Y. Effect of transcranial direct current stimulation on postpartum depression: A study protocol for a randomized controlled trial. Frontiers in psychology. vol 14. 2023-03-06. PMID:36874857. |
it may also ease depression indirectly by promoting the production and release of the neurotransmitter gaba. |
2023-03-06 |
2023-08-14 |
Not clear |
| Zhishuo Wang, Chenghua Yan, Qizhen Du, Yuying Huang, Xuezhen Li, Dan Zeng, Ruizhi Mao, Rama Krishna Gurram, Shipeng Cheng, Wangpeng Gu, Lin Zhu, Weiguo Fan, Liyan Ma, Zhiyang Ling, Ju Qiu, Dangsheng Li, Enmei Liu, Yaguang Zhang, Yiru Fang, Jinfang Zhu, Bing Su. HTR2A agonists play a therapeutic role by restricting ILC2 activation in papain-induced lung inflammation. Cellular & molecular immunology. 2023-02-23. PMID:36823235. |
here, we demonstrated the negative correlation between the depression-associated monoamine neurotransmitter serotonin and secretion of the cytokines il-5 and il-13 by ilc2s in individuals with depression. |
2023-02-23 |
2023-08-14 |
mouse |
| Pradeep Paudel, Se Eun Park, Su Hui Seong, Fazlin Mohd Fauzi, Hyun Ah Jung, Jae Sue Cho. Bromophenols from Journal of integrative neuroscience. vol 22. issue 1. 2023-02-01. PMID:36722239. |
bromophenols from cholecystokinin (cck) is one of the most abundant peptides in the central nervous system and is believed to function as a neurotransmitter as well as a gut hormone with an inverse correlation of its level to anxiety and depression. |
2023-02-01 |
2023-08-14 |
Not clear |
| Shrujna Patel, Brooke A Keating, Russell C Dal. Anti-inflammatory properties of commonly used psychiatric drugs. Frontiers in neuroscience. vol 16. 2023-01-27. PMID:36704001. |
instead, therapeutics are focused on symptoms and syndromes, largely driven by neurotransmitter hypotheses, such as serotonin or dopamine hypotheses of depression. |
2023-01-27 |
2023-08-14 |
human |
| Geoffrey A Dunn, Jacqueline R Thompson, A J Mitchell, Samantha Papadakis, Matthew Selby, Damien Fair, Hanna C Gustafsson, Elinor L Sulliva. Perinatal Western-style diet alters serotonergic neurons in the macaque raphe nuclei. Frontiers in neuroscience. vol 16. 2023-01-27. PMID:36704012. |
dysfunction in this important neurotransmitter system is connected to behavioral disorders such as depression and anxiety. |
2023-01-27 |
2023-08-14 |
monkey |
| Alessia Fiore, Paolo Preziosa, Nicolò Tedone, Monica Margoni, Carmen Vizzino, Damiano Mistri, Mor Gueye, Maria A Rocca, Massimo Filipp. Correspondence among gray matter atrophy and atlas-based neurotransmitter maps is clinically relevant in multiple sclerosis. Molecular psychiatry. 2023-01-19. PMID:36658334. |
no significant association between gm atrophy and neurotransmitter maps was found for depression. |
2023-01-19 |
2023-08-14 |
Not clear |
| Yuxi Guo, Xuefeng Chen, Pin Gong, Zixuan Li, Yanping Wu, Jie Zhang, Jiating Wang, Wenbo Yao, Wenjuan Yang, Fuxin Che. Advances in the mechanisms of polysaccharides in alleviating depression and its complications. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 109. 2023-01-07. PMID:36610126. |
the pathogenesis of depression is complex and is associated with abnormal neurotransmitter levels, activation of the hypothalamic-pituitary-adrenal (hpa) axis, inflammation, and gut flora-related disorders. |
2023-01-07 |
2023-08-14 |
Not clear |
| Ibrahim M Ibrahim, Mohammed Alsieni, Sami G Almalki, Yaser E Alqurashi, Vinay Kuma. Comparative evaluation of natural neuroprotectives and their combinations on chronic immobilization stress-induced depression in experimental mice. 3 Biotech. vol 13. issue 1. 2022-12-26. PMID:36568496. |
the result found the protective effect of these phytoconstituents and their combinations against cis-induced depression due to their ability to suppress oxidative stress, restore mitochondria, hpa-axis modulation, neurotransmitter level, stress hormones, and inflammatory markers. |
2022-12-26 |
2023-08-14 |
mouse |
| Neha Irfan, Arun Nair, Jessica Bhaskaran, Maksuda Akter, Tabitha Watt. Review of the Current Knowledge of Reactive Attachment Disorder. Cureus. vol 14. issue 11. 2022-12-14. PMID:36514636. |
neurobiological changes in patients with rad have been shown to be substantially significant with features such as loss of grey matter volume and neurotransmitter deficiencies that not only impact the ability to form healthy attachments but also increase the risk of comorbidities such as depression and anxiety. |
2022-12-14 |
2023-08-14 |
Not clear |
| Jiajia Duan, Wei Wang, Tao Jiang, Xiaoyang Bai, Chuanxin Li. Viral metagenomics combined with metabolomics reveals the role of gut viruses in mouse model of depression. Frontiers in microbiology. vol 13. 2022-12-02. PMID:36458183. |
however, the relationship between the effect of gut virome on neurotransmitter metabolism and depression is unknown. |
2022-12-02 |
2023-08-14 |
mouse |
| Amber N Edinoff, Keerthiga Raveendran, Marc A Colon, Bennett H Thomas, Katie A Trettin, Grace W Hunt, Adam M Kaye, Elyse M Cornett, Alan D Kay. Selective Serotonin Reuptake Inhibitors and Associated Bleeding Risks: A Narrative and Clinical Review. Health psychology research. vol 10. issue 4. 2022-11-25. PMID:36425234. |
serotonin is the most widely studied neurotransmitter in the pathophysiology of depression, with studies showing that reduced central serotonin synthesis leads to depressive symptoms in individuals at risk for depression. |
2022-11-25 |
2023-08-14 |
Not clear |
| Hendrik Bussmann, Hanns Häberlein, Georg Boonen, Jürgen Drewe, Veronika Butterweck, Sebastian Franke. Effect of St. John's wort extract Ze 117 on the lateral mobility of β Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 157. 2022-11-17. PMID:36395608. |
effect of st. john's wort extract ze 117 on the lateral mobility of β depression has been associated with altered signal transduction of serotonergic, dopaminergic and adrenergic neurotransmitter systems in the brain. |
2022-11-17 |
2023-08-14 |
Not clear |
| Kurt A Jellinge. The pathobiological basis of depression in Parkinson disease: challenges and outlooks. Journal of neural transmission (Vienna, Austria : 1996). 2022-11-02. PMID:36322206. |
although its diagnosis is based on standard criteria, due to overlap with other symptoms related to pd or to side effects of treatment, depression is frequently underdiagnosed and undertreated. dpd has been related to a variety of pathogenic mechanisms associated with the underlying neurodegenerative process, in particular dysfunction of neurotransmitter systems (dopaminergic, serotonergic and noradrenergic), as well as to disturbances of cortico-limbic, striato-thalamic-prefrontal, mediotemporal-limbic networks, with disruption in the topological organization of functional mood-related, motor and other essential brain network connections due to alterations in the blood-oxygen-level-dependent (bold) fluctuations in multiple brain areas. |
2022-11-02 |
2023-08-14 |
Not clear |