| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shi-jing Huang, Xian-hui Zhang, Yan-yun Wang, Ju-hua Pan, Han-ming Cui, Su-ping Fang, Wei Wu, Jun Zheng, Duo-jiao Li, Ge Ba. Effects of Kaixin Jieyu Decoction () on behavior, monoamine neurotransmitter levels, and serotonin receptor subtype expression in the brain of a rat depression model. Chinese journal of integrative medicine. vol 20. issue 4. 2016-10-24. PMID:24567255. |
to determine the mechanisms underlying the anti-depressant effects of kaixin jieyu decoction (, kjd) by investigating the effects of kjd on behavior, monoamine neurotransmitter levels, and serotonin (5-ht) receptor subtype expression in the brain in a rat model of depression. |
2016-10-24 |
2023-08-12 |
rat |
| Jana Ruda-Kucerova, Petra Amchova, Tereza Havlickova, Pavel Jerabek, Zuzana Babinska, Petr Kacer, Kamila Syslova, Alexandra Sulcova, Magdalena Sustkova-Fiserov. Reward related neurotransmitter changes in a model of depression: An in vivo microdialysis study. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 16. issue 7. 2016-08-17. PMID:26444572. |
reward related neurotransmitter changes in a model of depression: an in vivo microdialysis study. |
2016-08-17 |
2023-08-13 |
rat |
| Jana Ruda-Kucerova, Petra Amchova, Tereza Havlickova, Pavel Jerabek, Zuzana Babinska, Petr Kacer, Kamila Syslova, Alexandra Sulcova, Magdalena Sustkova-Fiserov. Reward related neurotransmitter changes in a model of depression: An in vivo microdialysis study. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 16. issue 7. 2016-08-17. PMID:26444572. |
the aim of this study was to elucidate the neurotransmitter changes in a rat model of depression by measuring their levels in the nucleus accumbens shell, which is typically involved in the drug of abuse acquisition mechanism. |
2016-08-17 |
2023-08-13 |
rat |
| Carlos Alberto Yasin Wayhs, Helena Maria Tannhauser Barros, Carmen Regla Varga. GABAergic Modulation in Diabetic Encephalopathy-Related Depression. Current pharmaceutical design. vol 21. issue 34. 2016-08-15. PMID:26365139. |
data presented from literature support the association between gaba and depressive- like behaviors in diabetic encephalopathy, being this neurotransmitter a potential target for the treatment of diabetes, depression and related comorbidities. |
2016-08-15 |
2023-08-13 |
human |
| M R Kasimov, G F Zakyrjanova, A R Giniatullin, A L Zefirov, A M Petro. Similar oxysterols may lead to opposite effects on synaptic transmission: Olesoxime versus 5α-cholestan-3-one at the frog neuromuscular junction. Biochimica et biophysica acta. vol 1861. issue 7. 2016-08-02. PMID:27102612. |
we found that olesoxime slightly increased evoked neurotransmitter release in response to a single stimulus and significantly reduced synaptic depression during high frequency activity. |
2016-08-02 |
2023-08-13 |
Not clear |
| K Fukud. Integrated theory to unify status among schizophrenia and manic depressive illness. Medical hypotheses. vol 85. issue 4. 2016-07-12. PMID:26141636. |
although decreased serotonin activity has been reported in both depression and mania, it is important to investigate the interaction between serotonin and other neurotransmitter systems. |
2016-07-12 |
2023-08-13 |
Not clear |
| Serkan Zincir, Pelin Öztürk, Ali Emrah Bilgen, Filiz İzci, Cihad Yükseli. Levels of serum immunomodulators and alterations with electroconvulsive therapy in treatment-resistant major depression. Neuropsychiatric disease and treatment. vol 12. 2016-07-01. PMID:27366071. |
the consideration of the relationship between the immune endocrine neurotransmitter systems could contribute to new theories regarding the mechanism of antidepressant treatment and biology of depression. |
2016-07-01 |
2023-08-13 |
Not clear |
| J E Robinson, J Paluch, D K Dickman, W J Joine. ADAR-mediated RNA editing suppresses sleep by acting as a brake on glutamatergic synaptic plasticity. Nature communications. vol 7. 2016-06-09. PMID:26813350. |
collectively these changes lead to sustained neurotransmitter release under conditions that would otherwise result in synaptic depression. |
2016-06-09 |
2023-08-13 |
drosophila_melanogaster |
| M Aquib, A K Najmi, M Akhta. Antidepressant Effect of Thymoquinone in Animal Models of Depression. Drug research. vol 65. issue 9. 2016-06-07. PMID:25207705. |
the present study was carried out to determine the role of thymoquinone (tq) in modulating the levels of neurotransmitter and reducing the oxidative stress in animal models of depression. |
2016-06-07 |
2023-08-13 |
Not clear |
| Leonardo Munari, Gustavo Provensi, Maria Beatrice Passani, Nicoletta Galeotti, Tommaso Cassano, Fernando Benetti, Renato Corradetti, Patrizio Blandin. Brain Histamine Is Crucial for Selective Serotonin Reuptake Inhibitors' Behavioral and Neurochemical Effects. The international journal of neuropsychopharmacology. vol 18. issue 10. 2016-06-01. PMID:25899065. |
the neurobiological changes underlying depression resistant to treatments remain poorly understood, and failure to respond to selective serotonin reuptake inhibitors may result from abnormalities of neurotransmitter systems that excite serotonergic neurons, such as histamine. |
2016-06-01 |
2023-08-13 |
Not clear |
| Lorenz Deutschenbaur, Johannes Beck, Anna Kiyhankhadiv, Markus Mühlhauser, Stefan Borgwardt, Marc Walter, Gregor Hasler, Daniel Sollberger, Undine E Lan. Role of calcium, glutamate and NMDA in major depression and therapeutic application. Progress in neuro-psychopharmacology & biological psychiatry. vol 64. 2016-05-31. PMID:25747801. |
hence, a steady accumulation of evidence supporting a role for the excitatory amino acid neurotransmitter (eaa) glutamate in the treatment of depression has been observed in the last years. |
2016-05-31 |
2023-08-13 |
Not clear |
| Matthew B Warren, Abbie Pringle, Catherine J Harme. A neurocognitive model for understanding treatment action in depression. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 370. issue 1677. 2016-05-31. PMID:26240428. |
characterizing the effects of pharmacological manipulations of key neurotransmitter systems can also help reveal the neurochemical underpinnings of emotional processing and how common antidepressant drugs may work in the treatment of depression and anxiety. |
2016-05-31 |
2023-08-13 |
human |
| Zhen Li, Shu-Cheng An, Jiang-Na L. [The interaction between gamma-aminobutyric acid and other related neurotransmitters in depression]. Sheng li ke xue jin zhan [Progress in physiology]. vol 45. issue 3. 2016-05-26. PMID:25219270. |
gamma-aminobutyric acid (gaba) is the major inhibitory neurotransmitter of the central nervous system (cns) in mammalian, which involved in several mood disorders such as anxiety, depression and schizophrenia. |
2016-05-26 |
2023-08-13 |
Not clear |
| Didier Meulendijks, Saheed Khan, Cornelis H W Koks, Alwin D R Huitema, Jan H M Schellens, Jos H Beijne. Baclofen overdose treated with continuous venovenous hemofiltration. European journal of clinical pharmacology. vol 71. issue 3. 2016-05-13. PMID:25567218. |
overdose with baclofen, a derivative of the inhibitory neurotransmitter γ-aminobutyric acid, may lead to severe respiratory and central nervous system depression and can be life-threatening. |
2016-05-13 |
2023-08-13 |
Not clear |
| K Hüfner, A Oberguggenberger, C Kohl, S Geisler, E Gamper, V Meraner, J Egeter, M Hubalek, B Beer, D Fuchs, B Sperner-Unterwege. Levels in neurotransmitter precursor amino acids correlate with mental health in patients with breast cancer. Psychoneuroendocrinology. vol 60. 2016-05-02. PMID:26112459. |
in the current study we investigated the association of neurotransmitter precursor amino acids with a diagnosis of depression or state anxiety in 154 subjects suffering from breast cancer (bca(+)), depression (dpr(+)), both or neither. |
2016-05-02 |
2023-08-13 |
human |
| Brian E Leonar. Stress, norepinephrine and depression. Acta neuropsychiatrica. vol 14. issue 4. 2016-03-18. PMID:26984329. |
in this review, evidence is presented to show how the impact of stress on the central sympathetic system leads to changes in the endocrine, immune and neurotransmitter axes which underlie the main clinical symptoms of depression. |
2016-03-18 |
2023-08-13 |
Not clear |
| P J Vermeulen, F G Zitma. Benzodiazepines in perspective (II): The GABAA-Benzodiazepine Receptor Ligands. Acta neuropsychiatrica. vol 12. issue 1. 2016-03-16. PMID:26976680. |
it is the first allosteric modulatory site on a neurotransmitter receptor that has been found to mediate two opposite functions: facilitation and depression of gabaa-r function. |
2016-03-16 |
2023-08-13 |
Not clear |
| Jordy van Enkhuizen, David S Janowsky, Berend Olivier, Arpi Minassian, William Perry, Jared W Young, Mark A Geye. The catecholaminergic-cholinergic balance hypothesis of bipolar disorder revisited. European journal of pharmacology. vol 753. 2016-03-14. PMID:25107282. |
despite increasing evidence supporting this hypothesis, a relationship between these two neurotransmitter systems that could explain cycling between states of depression and mania is missing. |
2016-03-14 |
2023-08-13 |
human |
| Giovanni Camardese, Luisa De Risio, Marco Di Nicola, Lorella Pucci, Fabrizio Cocciolillo, Pietro Bria, Alessandro Giordano, Luigi Janiri, Daniela Di Giud. Changes of dopamine transporter availability in depressed patients with and without anhedonia: a 123I-N-ω-fluoropropyl-carbomethoxy-3β- (4-Iodophenyl)tropane SPECT study. Neuropsychobiology. vol 70. issue 4. 2016-02-29. PMID:25613182. |
dopamine is an important neurotransmitter involved in the pathophysiology of depression and anhedonia. |
2016-02-29 |
2023-08-13 |
Not clear |
| Sarah G Helton, Falk W Lohof. Serotonin pathway polymorphisms and the treatment of major depressive disorder and anxiety disorders. Pharmacogenomics. vol 16. issue 5. 2016-01-19. PMID:25916524. |
most antidepressant drugs for the treatment of depression and anxiety disorders have effects on the serotonergic neurotransmitter system; thus, genetic polymorphisms in the genes involved in this pathway represent logical candidates for investigation. |
2016-01-19 |
2023-08-13 |
Not clear |