| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ying Wu, Fumiko Kawasaki, Richard W Ordwa. Properties of short-term synaptic depression at larval neuromuscular synapses in wild-type and temperature-sensitive paralytic mutants of Drosophila. Journal of neurophysiology. vol 93. issue 5. 2005-06-13. PMID:15845998. |
these findings reveal novel properties of short-term synaptic depression and suggest that complementary genetic analysis of larval and adult neuromuscular synapses will further define the in vivo mechanisms of neurotransmitter release and short-term synaptic plasticity. |
2005-06-13 |
2023-08-12 |
drosophila_melanogaster |
| A A Russo-Neustadt, M J Che. Brain-derived neurotrophic factor and antidepressant activity. Current pharmaceutical design. vol 11. issue 12. 2005-06-02. PMID:15892658. |
our discussion starts with the original observations of monoaminergic neurotransmitter dysfunction that served as the basis for early antidepressant drug development, and outlines evidence for neurodegeneration and functional deficits existing with chronic stress and depression. |
2005-06-02 |
2023-08-12 |
Not clear |
| Chirisse Taylor, Ashwana D Fricker, Lakshmi A Devi, Ivone Gome. Mechanisms of action of antidepressants: from neurotransmitter systems to signaling pathways. Cellular signalling. vol 17. issue 5. 2005-05-26. PMID:15683730. |
in this review, we describe the different neurotransmitter systems that are affected by anxiety and depression and how they are modulated by antidepressant treatment with a focus on signaling molecules and pathways that are activated during neurotransmitter receptor induced neurogenesis. |
2005-05-26 |
2023-08-12 |
Not clear |
| K Hashimoto, M Kan. [Calcium dependent forms of synaptic plasticity in cerebellar Purkinje cells]. Clinical calcium. vol 11. issue 11. 2005-05-10. PMID:15775659. |
at the three types of synapses described above, elevation of [ca(2+)](i) also causes short-term depression of neurotransmitter release from presynaptic terminals. |
2005-05-10 |
2023-08-12 |
Not clear |
| Patricia L Haynes, John R McQuaid, John Kelsoe, Mark Rapaport, J Christian Gilli. Affective state and EEG sleep profile in response to rapid tryptophan depletion in recently recovered nonmedicated depressed individuals. Journal of affective disorders. vol 83. issue 2-3. 2005-04-22. PMID:15555723. |
tfd is thought to reduce cerebral serotonin, a neurotransmitter implicated in depression. |
2005-04-22 |
2023-08-12 |
Not clear |
| Jolanta Rabe-Jabłońska, Adam Mille. [Links between pain and depression]. Psychiatria polska. vol 39. issue 1. 2005-04-21. PMID:15771150. |
presently we know at least five kinds of links between depression and pain: 1) depression appeared prior to the start of pain, 2) depression is a consequence of chronic pain and stress, 3) depressive episodes cause an increase of risk of next affective episodes in patients with chronic pain, 4) psychologic factors play an important role in the development of depressive symptoms, 5) altered balance between noradrenergic and serotonergic pathways and disregulation of other neurotransmitter systems (cholinergic, gaba-ergic, dopaminergic) and neuropeptides may cause chronic pain and depressive disorder. |
2005-04-21 |
2023-08-12 |
Not clear |
| Hymie Anisman, Zul Merali, Michael O Poulter, Shawn Hayle. Cytokines as a precipitant of depressive illness: animal and human studies. Current pharmaceutical design. vol 11. issue 8. 2005-04-06. PMID:15777247. |
interleukin-2 (il-2) induces less profound sickness, but elicits anhedonia, a key symptom of depression; (2) neuroendocrine and central neurotransmitter changes, reminiscent of those implicated in depression, may be elicited by some of these cytokines, and these effects are exacerbated by stressors; (3) severe depressive illness is accompanied by elevations of cytokine production or levels, although these effects are not necessarily attenuated with antidepressant medication; and (4) immunotherapy, using il-2 or ifn-alpha, promote depressive symptoms that are attenuated by antidepressant treatment. |
2005-04-06 |
2023-08-12 |
human |
| Hymie Anisman, Zul Merali, Michael O Poulter, Shawn Hayle. Cytokines as a precipitant of depressive illness: animal and human studies. Current pharmaceutical design. vol 11. issue 8. 2005-04-06. PMID:15777247. |
it is proposed that chronic cytokine elevations engender neuroendocrine and brain neurotransmitter changes that are interpreted by the brain as being stressors, and contribute to the development of depression. |
2005-04-06 |
2023-08-12 |
human |
| I Petrakis, J Krysta. Neuroscience: implications for treatment. Alcohol health and research world. vol 21. issue 2. 2005-03-17. PMID:15704353. |
medications that affect the neurotransmitter serotonin, however, may alleviate symptoms of anxiety and depression in alcoholics without affecting the alcoholism itself. |
2005-03-17 |
2023-08-12 |
Not clear |
| H S Sun, H-W Tsai, H-C Ko, F-M Chang, T-L Ye. Association of tryptophan hydroxylase gene polymorphism with depression, anxiety and comorbid depression and anxiety in a population-based sample of postpartum Taiwanese women. Genes, brain, and behavior. vol 3. issue 6. 2005-03-15. PMID:15544576. |
serotonin is the biogenic amine neurotransmitter most commonly associated with depression and anxiety. |
2005-03-15 |
2023-08-12 |
human |
| Gyöngyi Gesztely. [Primary headache and depression]. Orvosi hetilap. vol 145. issue 48. 2005-03-01. PMID:15638035. |
this theory is supported by the role of the same neurotransmitter systems (mostly serotonin and dopamine) in headaches as well as in depression. |
2005-03-01 |
2023-08-12 |
Not clear |
| Raymond W Lam, Cai Song, Lakshmi N Yatha. Does neuroimmune dysfunction mediate seasonal mood changes in winter depression? Medical hypotheses. vol 63. issue 4. 2005-02-15. PMID:15324998. |
the etiology of winter depression (seasonal affective disorder, or sad) is not known, but a number of studies have provided support for both photoperiod and neurotransmitter hypotheses. |
2005-02-15 |
2023-08-12 |
Not clear |
| Linda L Carpenter, Francisco A Moreno, Mitchel A Kling, George M Anderson, William T Regenold, David M Labiner, Lawrence H Pric. Effect of vagus nerve stimulation on cerebrospinal fluid monoamine metabolites, norepinephrine, and gamma-aminobutyric acid concentrations in depressed patients. Biological psychiatry. vol 56. issue 6. 2004-11-08. PMID:15364040. |
cerebrospinal fluid (csf) studies in epilepsy patients show that vns alters concentrations of monamines and gamma-aminobutyric acid (gaba), neurotransmitter systems possibly involved in the pathogenesis of depression. |
2004-11-08 |
2023-08-12 |
Not clear |
| S Rapp, M Baader, M Hu, C Jennen-Steinmetz, F A Henn, J Thom. Differential regulation of synaptic vesicle proteins by antidepressant drugs. The pharmacogenomics journal. vol 4. issue 2. 2004-11-04. PMID:14708000. |
synaptic vesicle proteins (svp) play a critical role in neurotransmitter release and neural plasticity, and have been implicated in the pathophysiology of psychiatric disorders such as depression. |
2004-11-04 |
2023-08-12 |
rat |
| Maria Teresa Tebano, Annita Pintor, Claudio Frank, Maria Rosaria Domenici, Alberto Martire, Rita Pepponi, Rosa Luisa Potenza, Rosa Grieco, Patrizia Popol. Adenosine A2A receptor blockade differentially influences excitotoxic mechanisms at pre- and postsynaptic sites in the rat striatum. Journal of neuroscience research. vol 77. issue 1. 2004-08-24. PMID:15197743. |
in rat corticostriatal slices, zm 241385 (30-100 nm) significantly reduced 4-aminopyridine (4-ap)-induced paired-pulse inhibition (ppi; an index of neurotransmitter release), whereas it worsened the depression of field potential amplitude elicited by n-methyl-d-aspartate (nmda; 12.5 and 50 microm). |
2004-08-24 |
2023-08-12 |
rat |
| Fan Jia, Xiaoqiao Xie, Yifeng Zho. Short-term depression of synaptic transmission from rat lateral geniculate nucleus to primary visual cortex in vivo. Brain research. vol 1002. issue 1-2. 2004-06-24. PMID:14988046. |
our results suggest that the presynaptic ca(2+)-dependent neurotransmitter depletion and postsynaptic gabaergic inhibition may be crucial for short-term synaptic depression in the geniculo-cortical pathway. |
2004-06-24 |
2023-08-12 |
rat |
| Francesco Crespi, Anna C Croce, Sabrina Fiorani, Barbara Masala, Christian Heidbreder, Giovanni Bottirol. Autofluorescence spectrofluorometry of central nervous system (CNS) neuromediators. Lasers in surgery and medicine. vol 34. issue 1. 2004-06-21. PMID:14755423. |
changes in the neurotransmitter 5-hydroxytriptamine (5-ht) are related to psychiatric diseases such as depression and anxiety. |
2004-06-21 |
2023-08-12 |
Not clear |
| Tsung-Ping Su, Teruo Hayash. Understanding the molecular mechanism of sigma-1 receptors: towards a hypothesis that sigma-1 receptors are intracellular amplifiers for signal transduction. Current medicinal chemistry. vol 10. issue 20. 2004-05-20. PMID:12871086. |
these include the regulation of ip3 receptors and calcium signaling at the endoplasmic reticulum, mobilization of cytoskeletal adaptor proteins, modulation of nerve growth factor-induced neurite sprouting, modulation of neurotransmitter release and neuronal firing, modulation of potassium channels as a regulatory subunit, alteration of psychostimulant-induced gene expression, and blockade of spreading depression. |
2004-05-20 |
2023-08-12 |
Not clear |
| Michael B Robinso. Signaling pathways take aim at neurotransmitter transporters. Science's STKE : signal transduction knowledge environment. vol 2003. issue 207. 2004-02-23. PMID:14600294. |
neurotransmitter transporters are the target of various pharmacological agents used to treat psychological or cognitive conditions, such as depression and attention-deficit disorder. |
2004-02-23 |
2023-08-12 |
Not clear |
| Ian A Paul, Phil Skolnic. Glutamate and depression: clinical and preclinical studies. Annals of the New York Academy of Sciences. vol 1003. 2004-02-13. PMID:14684451. |
the past decade has seen a steady accumulation of evidence supporting a role for the excitatory amino acid (eaa) neurotransmitter, glutamate, and its receptors in depression and antidepressant activity. |
2004-02-13 |
2023-08-12 |
Not clear |