| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vincent Chin-Hung Chen, Yu-Syuan Chou, Yuan-Hsiung Tsai, Yin-Cheng Huang, Roger S McIntyre, Jun-Cheng Wen. Resting-State Functional Connectivity and Brain Network Abnormalities in Depressive Patients with Suicidal Ideation. Brain topography. vol 34. issue 2. 2021-04-26. PMID:33420533. |
we also found several functional connectivity of the brain areas, such as hippocampus, cuneus, and frontal regions, in the si group correlated with hamilton depression rating scale (ham-d) and hospital anxiety and depression scale (hads). |
2021-04-26 |
2023-08-13 |
human |
| Cilene Lino de Oliveira, Juliana Aparecida Bolzan, Alexandre Surget, Catherine Belzun. Do antidepressants promote neurogenesis in adult hippocampus? A systematic review and meta-analysis on naive rodents. Pharmacology & therapeutics. vol 210. 2021-04-21. PMID:32109488. |
the neurogenic hypothesis of depression states that adult hippocampal neurogenesis is disrupted by stress and depression and is recovered by chronic treatments with antidepressants. |
2021-04-21 |
2023-08-13 |
Not clear |
| Samantha Hubachek, Morgan Botdorf, Tracy Riggins, Hoi-Chung Leong, Daniel N Klein, Lea R Doughert. Hippocampal subregion volume in high-risk offspring is associated with increases in depressive symptoms across the transition to adolescence. Journal of affective disorders. vol 281. 2021-04-21. PMID:33348179. |
the hippocampus has been implicated in the pathophysiology of depression. |
2021-04-21 |
2023-08-13 |
Not clear |
| Samantha Hubachek, Morgan Botdorf, Tracy Riggins, Hoi-Chung Leong, Daniel N Klein, Lea R Doughert. Hippocampal subregion volume in high-risk offspring is associated with increases in depressive symptoms across the transition to adolescence. Journal of affective disorders. vol 281. 2021-04-21. PMID:33348179. |
this study examined whether youth hippocampal subregion volumes were differentially associated with maternal depression history and youth's depressive symptoms across the transition to adolescence. |
2021-04-21 |
2023-08-13 |
Not clear |
| Lin Li, Yuting Zou, Baoe Liu, Runan Yang, Jingjian Yang, Minghao Sun, Zijing Li, Xiumei Xu, Guilin Li, Shuangmei Liu, Wolfgang Greffrath, Rolf-Detlef Treede, Guodong Li, Shangdong Lian. Correction to Contribution of the P2X4 Receptor in Rat Hippocampus to the Comorbidity of Chronic Pain and Depression. ACS chemical neuroscience. vol 12. issue 8. 2021-04-21. PMID:33830723. |
correction to contribution of the p2x4 receptor in rat hippocampus to the comorbidity of chronic pain and depression. |
2021-04-21 |
2023-08-13 |
rat |
| Silvia Vincentiis, Juliana A Alcantara, Patricia Rzezak, Daniel S Kerr, Wagner F Gattaz, Helio van der Linden, Bernardo Dos Santos, Francisco Arruda, Tiffany Chaim-Avancini, Mauricio H Serpa, Fernando Fernandes, Ricardo A Moreno, Geraldo F Busatto, Ruda Alessi, Renata Demarque, Kette D Valent. Genetic polymorphisms of the serotonin transporter are not related with depression in temporal lobe epilepsy caused by hippocampal sclerosis. Epilepsy & behavior : E&B. vol 117. 2021-04-20. PMID:33639436. |
genetic polymorphisms of the serotonin transporter are not related with depression in temporal lobe epilepsy caused by hippocampal sclerosis. |
2021-04-20 |
2023-08-13 |
Not clear |
| Hui Ai, Esther M Opmeer, Jan-Bernard C Marsman, Dick J Veltman, Nic J A van der Wee, André Aleman, Marie-José van To. Longitudinal brain changes in MDD during emotional encoding: effects of presence and persistence of symptomatology. Psychological medicine. vol 50. issue 8. 2021-04-16. PMID:31169102. |
the importance of the hippocampus and amygdala for disrupted emotional memory formation in depression is well-recognized, but it remains unclear whether functional abnormalities are state-dependent and whether they are affected by the persistence of depressive symptoms. |
2021-04-16 |
2023-08-13 |
Not clear |
| Haiyan Jiao, Hongjun Yang, Zhiyi Yan, Jianbei Chen, Mengbai Xu, Youming Jiang, Yueyun Liu, Zhe Xue, Qingyu Ma, Xiaojuan Li, Jiaxu Che. Traditional Chinese Formula Xiaoyaosan Alleviates Depressive-Like Behavior in CUMS Mice by Regulating PEBP1-GPX4-Mediated Ferroptosis in the Hippocampus. Neuropsychiatric disease and treatment. vol 17. 2021-04-16. PMID:33854318. |
this study aimed to establish a depression mouse model to explore the possible role of ferroptosis in the pathogenesis of depression, and observe the effects of xiaoyaosan on pebp1-gpx4-mediated ferroptosis in the hippocampus. |
2021-04-16 |
2023-08-13 |
mouse |
| Sujin Bae, Chandni Sheth, Margaret Legarreta, Erin McGlade, In Kyoon Lyoo, Deborah A Yurgelun-Tod. Volume and shape analysis of the Hippocampus and amygdala in veterans with traumatic brain injury and posttraumatic stress disorder. Brain imaging and behavior. vol 14. issue 5. 2021-04-13. PMID:31250267. |
there was a significant negative correlation between the hamilton rating scale for depression score (ham-d) and left hippocampal volume and a positive correlation between the ham-d score and left amygdalar volume in the tbi group. |
2021-04-13 |
2023-08-13 |
Not clear |
| Sujin Bae, Chandni Sheth, Margaret Legarreta, Erin McGlade, In Kyoon Lyoo, Deborah A Yurgelun-Tod. Volume and shape analysis of the Hippocampus and amygdala in veterans with traumatic brain injury and posttraumatic stress disorder. Brain imaging and behavior. vol 14. issue 5. 2021-04-13. PMID:31250267. |
the results of shape analysis suggest that alterations in the ca1 and subiculum subregions of hippocampus may have a role in depression and ptsd. |
2021-04-13 |
2023-08-13 |
Not clear |
| Katarzyna Bliźniewska-Kowalska, Piotr Gałecki, Janusz Szemraj, Monika Talarowsk. Expression of Selected Genes Involved in Neurogenesis in the Etiopathogenesis of Depressive Disorders. Journal of personalized medicine. vol 11. issue 3. 2021-04-13. PMID:33804468. |
(1) background: the neurogenic theory suggests that impaired neurogenesis within the dentate gyrus of the hippocampus is one of the factors causing depression. |
2021-04-13 |
2023-08-13 |
Not clear |
| Chengping Luo, Huimin Fan, Shaojun Li, Yuling Zo. Therapeutic of Candesartan and Music Therapy in Diabetic Retinopathy with Depression in Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2021. 2021-04-10. PMID:33833815. |
our data showed that chromatin aggregation and cytoplasmic vacuolation were observable in the hippocampal cells of the rats in the model group, while candesartan and music therapy could reduce morphological changes in the hippocampus of diabetic rats with depression. |
2021-04-10 |
2023-08-13 |
rat |
| Dawid Szczepankiewicz, Piotr Celichowski, Paweł A Kołodziejski, Ewa Pruszyńska-Oszmałek, Maciej Sassek, Przemysław Zakowicz, Ewa Banach, Wojciech Langwiński, Kosma Sakrajda, Joanna Nowakowska, Magdalena Socha, Ewelina Bukowska-Olech, Joanna Pawlak, Joanna Twarowska-Hauser, Leszek Nogowski, Janusz K Rybakowski, Aleksandra Szczepankiewic. Transcriptome Changes in Three Brain Regions during Chronic Lithium Administration in the Rat Models of Mania and Depression. International journal of molecular sciences. vol 22. issue 3. 2021-04-07. PMID:33498969. |
therefore, we aimed to analyze the gene expression profile in three brain regions (amygdala, frontal cortex and hippocampus) in the rat model of mania and depression during chronic lithium administration (2 and 4 weeks). |
2021-04-07 |
2023-08-13 |
rat |
| b' Bianca Besteher, Christian Gaser, Igor Nenadi\\xc4\\x8. Brain Structure and Subclinical Symptoms: A Dimensional Perspective of Psychopathology in the Depression and Anxiety Spectrum. Neuropsychobiology. vol 79. issue 4-5. 2021-04-06. PMID:31340207.' |
these studies show effects associated with subclinical symptoms in the hippocampus, anterior cingulate cortex, and anterior insula similar to major depression and changes in amygdala similar to anxiety disorders. |
2021-04-06 |
2023-08-13 |
human |
| Qingyu Zhang, Yiming Sun, Zhang He, Ying Xu, Xueting Li, Jianhua Ding, Ming Lu, Gang H. Kynurenine regulates NLRP2 inflammasome in astrocytes and its implications in depression. Brain, behavior, and immunity. vol 88. 2021-04-06. PMID:32283293. |
intraperitoneal injection of kyn activated nlrp2 inflammasome in astrocytes of hippocampus in mice, while nlrp2 knockdown in astrocytes abolished depressive-like behaviors in mice induced by kyn, suggesting the critical role of nlrp2 in kyn-induced depression. |
2021-04-06 |
2023-08-13 |
mouse |
| Fenghua Chen, Aksel B Bertelsen, Ida E Holm, Jens R Nyengaard, Raben Rosenberg, Karl-Anton Dorph-Peterse. Hippocampal volume and cell number in depression, schizophrenia, and suicide subjects. Brain research. vol 1727. 2021-04-05. PMID:31715144. |
we found the total volume and total numbers of neurons and glial cells similarly reduced by approximately 20% to 35% in depression and schizophrenia subjects relative to control subjects across all hippocampal regions. |
2021-04-05 |
2023-08-13 |
human |
| Fenghua Chen, Aksel B Bertelsen, Ida E Holm, Jens R Nyengaard, Raben Rosenberg, Karl-Anton Dorph-Peterse. Hippocampal volume and cell number in depression, schizophrenia, and suicide subjects. Brain research. vol 1727. 2021-04-05. PMID:31715144. |
the volume and number of cells are reduced in depression and schizophrenia subjects relative to control subjects across all hippocampal regions. |
2021-04-05 |
2023-08-13 |
human |
| Fenghua Chen, Aksel B Bertelsen, Ida E Holm, Jens R Nyengaard, Raben Rosenberg, Karl-Anton Dorph-Peterse. Hippocampal volume and cell number in depression, schizophrenia, and suicide subjects. Brain research. vol 1727. 2021-04-05. PMID:31715144. |
our findings imply that the hippocampus may be a common site of pathophysiology in depression and schizophrenia. |
2021-04-05 |
2023-08-13 |
human |
| Jodi L Pawluski, Rafaella Paravatou, Alan Even, Gael Cobraiville, Marianne Fillet, Nikolaos Kokras, Christina Dalla, Thierry D Charlie. Effect of sertraline on central serotonin and hippocampal plasticity in pregnant and non-pregnant rats. Neuropharmacology. vol 166. 2021-04-02. PMID:31935392. |
the aim of this study was to investigate how sertraline affects plasticity in the hippocampus, a brain area integral in depression and ssri efficacy (particularly in males), during late pregnancy and whether these effects differ from the effects of sertraline in non-pregnant females. |
2021-04-02 |
2023-08-13 |
rat |
| Yangzhi Peng, Yue Su, Yong Jian. Effect of the warming and tonifying kidney- yang recipe on monoamine neurotransmitters and pathological morphology of hippocampus tissue in depression model rats. Technology and health care : official journal of the European Society for Engineering and Medicine. vol 28. issue S1. 2021-04-02. PMID:32364156. |
effect of the warming and tonifying kidney- yang recipe on monoamine neurotransmitters and pathological morphology of hippocampus tissue in depression model rats. |
2021-04-02 |
2023-08-13 |
rat |