| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tao Jiang, Shuwei Hu, Shiyun Dai, Yiwen Yi, Tingting Wang, Xufeng Li, Mingcui Luo, Ke Li, Liaobin Chen, Hui Wang, Dan X. Programming changes of hippocampal miR-134-5p/SOX2 signal mediate the susceptibility to depression in prenatal dexamethasone-exposed female offspring. Cell biology and toxicology. 2021-02-23. PMID:33619658. |
programming changes of hippocampal mir-134-5p/sox2 signal mediate the susceptibility to depression in prenatal dexamethasone-exposed female offspring. |
2021-02-23 |
2023-08-13 |
rat |
| Tao Jiang, Shuwei Hu, Shiyun Dai, Yiwen Yi, Tingting Wang, Xufeng Li, Mingcui Luo, Ke Li, Liaobin Chen, Hui Wang, Dan X. Programming changes of hippocampal miR-134-5p/SOX2 signal mediate the susceptibility to depression in prenatal dexamethasone-exposed female offspring. Cell biology and toxicology. 2021-02-23. PMID:33619658. |
the programming effect mediated by the abnormal epigenetic modification could last from intrauterine to adulthood, which constitutes the intrauterine programming mechanism leading to hippocampal neurogenesis disorders and depression susceptibility in female offspring. |
2021-02-23 |
2023-08-13 |
rat |
| Minlan Yuan, Harry Rubin-Falcone, Xuejing Lin, Mina M Rizk, Jeffrey M Miller, M Elizabeth Sublette, Maria A Oquendo, Ainsley Burke, R Todd Ogden, J John Man. Smaller left hippocampal subfield CA1 volume is associated with reported childhood physical and/or sexual abuse in major depression: A pilot study. Journal of affective disorders. vol 272. 2021-02-15. PMID:32553377. |
smaller left hippocampal subfield ca1 volume is associated with reported childhood physical and/or sexual abuse in major depression: a pilot study. |
2021-02-15 |
2023-08-13 |
Not clear |
| Chuan Huang, Ju-Tao Che. Chronic retinoic acid treatment induces affective disorders by impairing the synaptic plasticity of the hippocampus. Journal of affective disorders. vol 274. 2021-02-15. PMID:32664002. |
it is believed that the development of depression results from alterations in synaptic transmission, especially in the hippocampus. |
2021-02-15 |
2023-08-13 |
Not clear |
| Chuan Huang, Ju-Tao Che. Chronic retinoic acid treatment induces affective disorders by impairing the synaptic plasticity of the hippocampus. Journal of affective disorders. vol 274. 2021-02-15. PMID:32664002. |
animal experiments and clinical studies have demonstrated that retinoids are essential components in hippocampal synaptic plasticity, and they have a close relationship with depression. |
2021-02-15 |
2023-08-13 |
Not clear |
| Shouhong Zhou, Shanshan Chen, Wenxia Xie, Xiaoxiao Guo, Jianfeng Zha. Microglia polarization of hippocampus is involved in the mechanism of Apelin-13 ameliorating chronic water immersion restraint stress-induced depression-like behavior in rats. Neuropeptides. vol 81. 2021-02-12. PMID:31932110. |
chronic stress induces the activation of hippocampal microglia, which produces many inflammatory mediators and mediates the occurrence of depression. |
2021-02-12 |
2023-08-13 |
rat |
| Katsuhiko Sakamoto, Sayaka Higo-Yamamoto, Yuichi Egi, Koyomi Miyazaki, Katsutaka Oish. Memory dysfunction and anxiety-like behavior in a mouse model of chronic sleep disorders. Biochemical and biophysical research communications. vol 529. issue 2. 2021-02-10. PMID:32703407. |
we then examined the hippocampal mrna expression of genes associated with learning and memory, and anxiety and depression. |
2021-02-10 |
2023-08-13 |
mouse |
| Jing Yang, Chaoqin Chen, Xiaoyuan Jin, Lu Liu, Jiajia Lin, Xianhui Kang, Shengmei Zh. Wfs1 and Related Molecules as Key Candidate Genes in the Hippocampus of Depression. Frontiers in genetics. vol 11. 2021-02-10. PMID:33552119. |
wfs1 and related molecules as key candidate genes in the hippocampus of depression. |
2021-02-10 |
2023-08-13 |
mouse |
| Jing Yang, Chaoqin Chen, Xiaoyuan Jin, Lu Liu, Jiajia Lin, Xianhui Kang, Shengmei Zh. Wfs1 and Related Molecules as Key Candidate Genes in the Hippocampus of Depression. Frontiers in genetics. vol 11. 2021-02-10. PMID:33552119. |
the hippocampus is a crucial region involved in depression and has been a therapeutic target for many antidepressants. |
2021-02-10 |
2023-08-13 |
mouse |
| Jing Yang, Chaoqin Chen, Xiaoyuan Jin, Lu Liu, Jiajia Lin, Xianhui Kang, Shengmei Zh. Wfs1 and Related Molecules as Key Candidate Genes in the Hippocampus of Depression. Frontiers in genetics. vol 11. 2021-02-10. PMID:33552119. |
thus, it is beneficial for comprehensive research to be carried out on the molecular mechanisms of the hippocampus involved in the pathogenesis of depression. |
2021-02-10 |
2023-08-13 |
mouse |
| Aaron S Heller, Rosemary C Bago. Is Hippocampal Replay a Mechanism for Anxiety and Depression? JAMA psychiatry. vol 77. issue 4. 2021-02-03. PMID:32022841. |
is hippocampal replay a mechanism for anxiety and depression? |
2021-02-03 |
2023-08-13 |
Not clear |
| Jie Kang, Di Wang, Yongchang Duan, Lin Zhai, Lin Shi, Fei Gu. Aerobic Exercise Prevents Depression via Alleviating Hippocampus Injury in Chronic Stressed Depression Rats. Brain sciences. vol 11. issue 1. 2021-01-26. PMID:33374661. |
aerobic exercise prevents depression via alleviating hippocampus injury in chronic stressed depression rats. |
2021-01-26 |
2023-08-13 |
rat |
| Jie Kang, Di Wang, Yongchang Duan, Lin Zhai, Lin Shi, Fei Gu. Aerobic Exercise Prevents Depression via Alleviating Hippocampus Injury in Chronic Stressed Depression Rats. Brain sciences. vol 11. issue 1. 2021-01-26. PMID:33374661. |
alleviating hippocampus injury may prevent depression development. |
2021-01-26 |
2023-08-13 |
rat |
| Jie Kang, Di Wang, Yongchang Duan, Lin Zhai, Lin Shi, Fei Gu. Aerobic Exercise Prevents Depression via Alleviating Hippocampus Injury in Chronic Stressed Depression Rats. Brain sciences. vol 11. issue 1. 2021-01-26. PMID:33374661. |
in contrast, ae upregulated phosphorylation of ampar receptor and brain-derived neurotrophic factor (bdnf) hippocampus in cums depression rats. |
2021-01-26 |
2023-08-13 |
rat |
| Jie Kang, Di Wang, Yongchang Duan, Lin Zhai, Lin Shi, Fei Gu. Aerobic Exercise Prevents Depression via Alleviating Hippocampus Injury in Chronic Stressed Depression Rats. Brain sciences. vol 11. issue 1. 2021-01-26. PMID:33374661. |
(4) conclusion: ae might be an efficient strategy for prevention of cums-induced depression via ameliorating hippocampus functions. |
2021-01-26 |
2023-08-13 |
rat |
| Luciana D'Alessio, Lucia Mesarosova, Jasper J Anink, Silvia Kochen, Patricia Solís, Silvia Oddo, Hector Konopka, Anand M Iyer, Angelika Mühlebner, Paul J Lucassen, Eleonora Aronica, Erwin A van Vlie. Reduced expression of the glucocorticoid receptor in the hippocampus of patients with drug-resistant temporal lobe epilepsy and comorbid depression. Epilepsia. vol 61. issue 8. 2021-01-22. PMID:32652588. |
reduced expression of the glucocorticoid receptor in the hippocampus of patients with drug-resistant temporal lobe epilepsy and comorbid depression. |
2021-01-22 |
2023-08-13 |
Not clear |
| Luciana D'Alessio, Lucia Mesarosova, Jasper J Anink, Silvia Kochen, Patricia Solís, Silvia Oddo, Hector Konopka, Anand M Iyer, Angelika Mühlebner, Paul J Lucassen, Eleonora Aronica, Erwin A van Vlie. Reduced expression of the glucocorticoid receptor in the hippocampus of patients with drug-resistant temporal lobe epilepsy and comorbid depression. Epilepsia. vol 61. issue 8. 2021-01-22. PMID:32652588. |
therefore, we set out to investigate expression of the gr in the hippocampus, an important brain region for hpa axis feedback, of patients with drug-resistant tle, with and without comorbid depression. |
2021-01-22 |
2023-08-13 |
Not clear |
| Yongxing Yan, Jun Wang, Changyang Zhong, Yan Zhang, Yingnan Wei, Huili Li. Effects of Endovascular Stent-Assisted Angioplasty on Cellular Metabolism in the Hippocampus of Elderly Patients with Symptomatic Vertebrobasilar Artery Stenosis. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-01-19. PMID:32390653. |
the montreal cognitive assessment scale (moca), hamilton depression self-assessment scale (hamd), and hamilton anxiety self-assessment scale (hama) were also used to evaluate the cognition, depression, and anxiety of patients at different time points of the study, and analyzed the correlation between the changes of cellular metabolism in the hippocampus and the scores of moca, hamd, and hama. |
2021-01-19 |
2023-08-13 |
Not clear |
| Rui Guo, Wei-Shuai Qin, Shuang-Yong Zhang, Shu-Ling Zhan. [Effects of modified Xiaoyao San on TLR4/NF-κB pathway in hippocampal microglia of LPS-induced depression model rats]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 36. issue 4. 2021-01-18. PMID:33167098. |
[effects of modified xiaoyao san on tlr4/nf-κb pathway in hippocampal microglia of lps-induced depression model rats]. |
2021-01-18 |
2023-08-13 |
rat |
| Rui Guo, Wei-Shuai Qin, Shuang-Yong Zhang, Shu-Ling Zhan. [Effects of modified Xiaoyao San on TLR4/NF-κB pathway in hippocampal microglia of LPS-induced depression model rats]. Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology. vol 36. issue 4. 2021-01-18. PMID:33167098. |
to investigate the effects of modified xiaoyao san on tlr4/nf-κb pathway in hippocampal microglia of lps-induced depression model rats, and to explore its antidepressant mechanism. |
2021-01-18 |
2023-08-13 |
rat |