| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Katarzyna Głombik, Jan Detka, Anna Kurek, Bogusława Budziszewsk. Impaired Brain Energy Metabolism: Involvement in Depression and Hypothyroidism. Frontiers in neuroscience. vol 14. 2020-12-22. PMID:33343282. |
furthermore, hypothyroidism disrupted the connection between glycolysis and the krebs cycle in the frontal cortex and hippocampus in the depression model used in this study. |
2020-12-22 |
2023-08-13 |
rat |
| Shengyan Xi, Guangxin Yue, Yueyun Liu, Yanan Wang, Yingkun Qiu, Zhigeng Li, Pei Ma, Tiegang Liu, Youming Jiang, Yuan Liang, Qun Liu, Jing Shi, Jiaxu Chen, Lifeng Yu. Free Wanderer Powder regulates AMPA receptor homeostasis in chronic restraint stress-induced rat model of depression with liver-depression and spleen-deficiency syndrome. Aging. vol 12. issue 19. 2020-12-19. PMID:33052137. |
together, these results suggest that fwp contains effective constituents and alleviates depression with ldsds by regulating ampa-type glutamate receptor homeostasis in amygdala and hippocampus. |
2020-12-19 |
2023-08-13 |
rat |
| b' Pavla \\xc4\\x8cermakov\\xc3\\xa1, Lenka Andr\\xc3\\xbdskov\\xc3\\xa1, Milan Br\\xc3\\xa1zdil, Kl\\xc3\\xa1ra Mare\\xc4\\x8dkov\\xc3\\xa. Socioeconomic deprivation in early life and symptoms of depression and anxiety in young adulthood: mediating role of hippocampal connectivity. Psychological medicine. 2020-12-17. PMID:33327969.' |
socioeconomic deprivation in early life and symptoms of depression and anxiety in young adulthood: mediating role of hippocampal connectivity. |
2020-12-17 |
2023-08-13 |
Not clear |
| Josh A Firth, Lee Smith, Jerome Sarris, Davy Vancampfort, Felipe Schuch, Andre F Carvalho, Marco Solmi, Alison R Yung, Brendon Stubbs, Joseph Firt. Handgrip Strength Is Associated With Hippocampal Volume and White Matter Hyperintensities in Major Depression and Healthy Controls: A UK Biobank Study. Psychosomatic medicine. vol 82. issue 1. 2020-12-14. PMID:31702599. |
handgrip strength is associated with hippocampal volume and white matter hyperintensities in major depression and healthy controls: a uk biobank study. |
2020-12-14 |
2023-08-13 |
Not clear |
| Kyung Hwa Lee, Jae Hyun Yoo, Jung Lee, Seong Hae Kim, Ji Youn Han, Soon-Beom Hong, Jiyoon Shin, Soo-Churl Cho, Jae-Won Kim, David A Bren. The indirect effect of peer problems on adolescent depression through nucleus accumbens volume alteration. Scientific reports. vol 10. issue 1. 2020-12-09. PMID:32733056. |
there was a significant indirect effect of peer problems on adolescent depression through nucleus accumbens (nacc) volume alteration, but not through the amygdala and hippocampal volumes. |
2020-12-09 |
2023-08-13 |
Not clear |
| Bhaswati Roy, Luke Ehlert, Rashmi Mullur, Matthew J Freeby, Mary A Woo, Rajesh Kumar, Sarah Cho. Regional Brain Gray Matter Changes in Patients with Type 2 Diabetes Mellitus. Scientific reports. vol 10. issue 1. 2020-12-07. PMID:32555374. |
gm volumes were significantly associated with anxiety (r = -0.456,p = 0.009), depression (r = -0.465,p = 0.01), and cognition (r = 0.455,p = 0.009) scores in regions associated with those regulations (prefrontal cortices, hippocampus, para hippocampus, amygdala, insula, cingulate, caudate, thalamus, and cerebellum) in t2dm patients. |
2020-12-07 |
2023-08-13 |
human |
| Swati Maitra, Nitin Khandelwal, Scherazad Kootar, Pooja Sant, Salil S Pathak, Sujatha Reddy, Annapoorna P K, Upadhyayula Suryanarayana Murty, Sumana Chakravarty, Arvind Kuma. Histone Lysine Demethylase JMJD2D/KDM4D and Family Members Mediate Effects of Chronic Social Defeat Stress on Mouse Hippocampal Neurogenesis and Mood Disorders. Brain sciences. vol 10. issue 11. 2020-12-01. PMID:33182385. |
this includes the cognitive circuitry, where the dynamic hippocampal dentate gyrus (dg) neurogenesis gets affected in depression and related affective disorders. |
2020-12-01 |
2023-08-13 |
mouse |
| Diane Joss, Sara W Lazar, Martin H Teiche. Effects of a mindfulness based behavioral intervention for young adults with childhood maltreatment history on hippocampal morphometry: a pilot MRI study with voxel-based morphometry. Psychiatry research. Neuroimaging. vol 301. 2020-11-30. PMID:32413812. |
within the mindfulness group, changes in hippocampal gmv were negatively associated with changes in perceived stress and depression severity and positively associated with enhancement in performance accuracy on the episodic memory task. |
2020-11-30 |
2023-08-13 |
human |
| Warren D Taylor, Yi Deng, Brian D Boyd, Manus J Donahue, Kimberly Albert, Maureen McHugo, Jason A Gandelman, Bennett A Landma. Medial temporal lobe volumes in late-life depression: effects of age and vascular risk factors. Brain imaging and behavior. vol 14. issue 1. 2020-11-17. PMID:30251182. |
substantial work associates late-life depression with hippocampal pathology. |
2020-11-17 |
2023-08-13 |
Not clear |
| Warren D Taylor, Yi Deng, Brian D Boyd, Manus J Donahue, Kimberly Albert, Maureen McHugo, Jason A Gandelman, Bennett A Landma. Medial temporal lobe volumes in late-life depression: effects of age and vascular risk factors. Brain imaging and behavior. vol 14. issue 1. 2020-11-17. PMID:30251182. |
moreover, the observed greater effect of age in the depressed groups is concordant with past longitudinal studies reporting greater hippocampal atrophy in late-life depression. |
2020-11-17 |
2023-08-13 |
Not clear |
| Aisouda Savadlou, Aurina Arnatkeviciute, Jeggan Tiego, Ziarih Hawi, Mark A Bellgrove, Alex Fornito, Chad Bousma. Impact of CYP2C19 genotype-predicted enzyme activity on hippocampal volume, anxiety, and depression. Psychiatry research. vol 288. 2020-11-17. PMID:32315880. |
impact of cyp2c19 genotype-predicted enzyme activity on hippocampal volume, anxiety, and depression. |
2020-11-17 |
2023-08-13 |
human |
| O Gokdemir, C Cetinkaya, H Gumus, I Aksu, M Kiray, M Ates, A Kiray, B Baykara, B Baykara, A R Sisman, N Uysa. The effect of exercise on anxiety- and depression-like behavior of aged rats. Biotechnic & histochemistry : official publication of the Biological Stain Commission. vol 95. issue 1. 2020-11-13. PMID:31264480. |
exercise in multiple sessions may increase the number of cells in the hippocampus, prefrontal cortex and amygdala, which may reduce senile anxiety and depression. |
2020-11-13 |
2023-08-13 |
rat |
| Katarzyna Głombik, Jan Detka, Joanna Góralska, Anna Kurek, Bogdan Solnica, Bogusława Budziszewsk. Brain Metabolic Alterations in Rats Showing Depression-Like and Obesity Phenotypes. Neurotoxicity research. vol 37. issue 2. 2020-11-12. PMID:31782099. |
in the case of the coexistence of depression and obesity, the most important changes were (1) the decrease in the membrane form of glut4, which may suggest weaker insulin action in the frontal cortex, and (2) the diminished glp-1r, which could cause neurodegenerative changes in the hippocampus. |
2020-11-12 |
2023-08-13 |
rat |
| Irene Sánchez-Rodríguez, Souhail Djebari, Sara Temprano-Carazo, David Vega-Avelaira, Raquel Jiménez-Herrera, Guillermo Iborra-Lázaro, Javier Yajeya, Lydia Jiménez-Díaz, Juan D Navarro-Lópe. Hippocampal long-term synaptic depression and memory deficits induced in early amyloidopathy are prevented by enhancing G-protein-gated inwardly rectifying potassium channel activity. Journal of neurochemistry. vol 153. issue 3. 2020-11-04. PMID:31875959. |
hippocampal long-term synaptic depression and memory deficits induced in early amyloidopathy are prevented by enhancing g-protein-gated inwardly rectifying potassium channel activity. |
2020-11-04 |
2023-08-13 |
mouse |
| Deanna M Barch, Elizabeth A Shirtcliff, Nourhan M Elsayed, Diana Whalen, Kirsten Gilbert, Alecia C Vogel, Rebecca Tillman, Joan L Lub. Testosterone and hippocampal trajectories mediate relationship of poverty to emotion dysregulation and depression. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 36. 2020-10-30. PMID:32839328. |
testosterone and hippocampal trajectories mediate relationship of poverty to emotion dysregulation and depression. |
2020-10-30 |
2023-08-13 |
Not clear |
| Deanna M Barch, Elizabeth A Shirtcliff, Nourhan M Elsayed, Diana Whalen, Kirsten Gilbert, Alecia C Vogel, Rebecca Tillman, Joan L Lub. Testosterone and hippocampal trajectories mediate relationship of poverty to emotion dysregulation and depression. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 36. 2020-10-30. PMID:32839328. |
here we test the hypothesis that one pathway involves hormone mechanisms (testosterone and dhea) that contribute to disruption of hippocampal brain development, which in turn contributes to perturbed emotion regulation and subsequent risk for depression. |
2020-10-30 |
2023-08-13 |
Not clear |
| Deanna M Barch, Elizabeth A Shirtcliff, Nourhan M Elsayed, Diana Whalen, Kirsten Gilbert, Alecia C Vogel, Rebecca Tillman, Joan L Lub. Testosterone and hippocampal trajectories mediate relationship of poverty to emotion dysregulation and depression. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 36. 2020-10-30. PMID:32839328. |
to do so, we used data from 167 children participating in the preschool depression study, a longitudinal study that followed children from preschool (ages 3 to 5 y) to late adolescence, and which includes prospective assessments of poverty in preschool, measures of testosterone, dhea, and hippocampal volume across school age and adolescence, and measures of emotion regulation and depression in adolescence. |
2020-10-30 |
2023-08-13 |
Not clear |
| Deanna M Barch, Elizabeth A Shirtcliff, Nourhan M Elsayed, Diana Whalen, Kirsten Gilbert, Alecia C Vogel, Rebecca Tillman, Joan L Lub. Testosterone and hippocampal trajectories mediate relationship of poverty to emotion dysregulation and depression. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 36. 2020-10-30. PMID:32839328. |
the relationship between early poverty and self-reported depression in adolescence was explained by serial mediation through testosterone to hippocampus to emotion dysregulation. |
2020-10-30 |
2023-08-13 |
Not clear |
| Run-Hui Tian, Yang Bai, Jing-Yang Li, Kai-Min Gu. Reducing PRLR expression and JAK2 activity results in an increase in BDNF expression and inhibits the apoptosis of CA3 hippocampal neurons in a chronic mild stress model of depression. Brain research. vol 1725. 2020-10-23. PMID:31545956. |
reducing prlr expression and jak2 activity results in an increase in bdnf expression and inhibits the apoptosis of ca3 hippocampal neurons in a chronic mild stress model of depression. |
2020-10-23 |
2023-08-13 |
mouse |
| Run-Hui Tian, Yang Bai, Jing-Yang Li, Kai-Min Gu. Reducing PRLR expression and JAK2 activity results in an increase in BDNF expression and inhibits the apoptosis of CA3 hippocampal neurons in a chronic mild stress model of depression. Brain research. vol 1725. 2020-10-23. PMID:31545956. |
therefore, the present study was conducted on the effect of prlr gene on brain derived neurotrophic factor (bdnf) expression and hippocampal neuron apoptosis through the establishment of cms-induced depression mouse models, with aims of providing a new and effective therapeutic option for depression. |
2020-10-23 |
2023-08-13 |
mouse |