| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yali Hou, Heng Qian, Ranqi Yao, Ziran Yu, Jing Wang, Jiaohua Dai, Wenqi Cui, Jian Li, Xiujuan Zha. Untargeted Metabolomics Revealed that Quercetin Inhibited Ferroptosis by Improving Metabolic Disorder in the Hippocampus of Perimenopausal Depression Model Rats. Molecular neurobiology. 2024-08-23. PMID:39179684. |
quercetin can improve perimenopausal depression by regulating hippocampal metabolic disorders and reducing hippocampal ferroptosis in rats. |
2024-08-23 |
2024-08-27 |
rat |
| Yali Hou, Heng Qian, Ranqi Yao, Ziran Yu, Jing Wang, Jiaohua Dai, Wenqi Cui, Jian Li, Xiujuan Zha. Untargeted Metabolomics Revealed that Quercetin Inhibited Ferroptosis by Improving Metabolic Disorder in the Hippocampus of Perimenopausal Depression Model Rats. Molecular neurobiology. 2024-08-23. PMID:39179684. |
untargeted metabolomics revealed that quercetin inhibited ferroptosis by improving metabolic disorder in the hippocampus of perimenopausal depression model rats. |
2024-08-23 |
2024-08-27 |
rat |
| Yali Hou, Heng Qian, Ranqi Yao, Ziran Yu, Jing Wang, Jiaohua Dai, Wenqi Cui, Jian Li, Xiujuan Zha. Untargeted Metabolomics Revealed that Quercetin Inhibited Ferroptosis by Improving Metabolic Disorder in the Hippocampus of Perimenopausal Depression Model Rats. Molecular neurobiology. 2024-08-23. PMID:39179684. |
this study aims to investigate the effect of quercetin on hippocampal metabolic disorder in perimenopausal depression rat models based on untargeted metabolomics technology. |
2024-08-23 |
2024-08-27 |
rat |
| Yaqi Song, Tianye Xu, Xiujuan Chen, Ning Wang, Zhongru Sun, Jinhua Chen, Jianguo Xia, Weizhong Tia. Brain structural changes in diabetic retinopathy patients: a combined voxel-based morphometry and surface-based morphometry study. Brain imaging and behavior. 2024-08-22. PMID:39172355. |
the left hippocampal gray matter volume (gmv) in patients with diabetic retinopathy was negatively correlated with disease duration (r = -0.478, p = 0.008) and self-rating depression scale (sas) score (r = -0.381, p = 0.038). |
2024-08-22 |
2024-08-24 |
Not clear |
| Ming Li, Fang Yang, Xiaoling Zhang, Hong Yang, Xingjin He, Zhongnan Mao, Liya Ma. Electroacupuncture attenuates depressive-like behaviors in poststroke depression mice through promoting hippocampal neurogenesis and inhibiting TLR4/NF-κB/NLRP3 signaling pathway. Neuroreport. 2024-08-21. PMID:39166408. |
electroacupuncture attenuates depressive-like behaviors in poststroke depression mice through promoting hippocampal neurogenesis and inhibiting tlr4/nf-κb/nlrp3 signaling pathway. |
2024-08-21 |
2024-08-23 |
mouse |
| Ming Li, Fang Yang, Xiaoling Zhang, Hong Yang, Xingjin He, Zhongnan Mao, Liya Ma. Electroacupuncture attenuates depressive-like behaviors in poststroke depression mice through promoting hippocampal neurogenesis and inhibiting TLR4/NF-κB/NLRP3 signaling pathway. Neuroreport. 2024-08-21. PMID:39166408. |
electroacupuncture was observed to mitigate depression symptoms and increase hippocampal neurogenesis in mice with psd, possibly by inhibiting tlr4/p38/nf-κb/nlrp3 pathways and improving the microglia-mediated inflammatory microenvironment in the hippocampus. |
2024-08-21 |
2024-08-23 |
mouse |
| V Kafetzopoulos, N Kokras, Filippos Katsaitis, N Sousa, H Leite-Almeida, I Sotiropoulos, C Dall. Prefrontal cortex-nucleus reuniens-hippocampus network exhibits sex-differentiated responses to stress and antidepressant treatment in rats. Psychopharmacology. 2024-08-20. PMID:39162717. |
we have recently shown that lesioning or inactivation of the nucleus reuniens (re), which interconnects the prefrontal cortex (pfc) and hippocampus, promoted resilience to stress in males, exerts an antidepressant effect in the forced swim test (fst) and prevents the development of behavioral and neurobiological alterations induced by the chronic mild stress model of depression. |
2024-08-20 |
2024-08-22 |
rat |
| Radwa N Muhammad, Mohammed A Albahairy, Mai A Abd El Fattah, Weam W Ibrahi. Empagliflozin-activated AMPK elicits neuroprotective properties in reserpine-induced depression via regulating dynamics of hippocampal autophagy/inflammation and PKCζ-mediated neurogenesis. Psychopharmacology. 2024-08-19. PMID:39158617. |
empagliflozin-activated ampk elicits neuroprotective properties in reserpine-induced depression via regulating dynamics of hippocampal autophagy/inflammation and pkcζ-mediated neurogenesis. |
2024-08-19 |
2024-08-21 |
Not clear |
| Yan-Bin Wei, Yong-Bo Wang, Jia-Yue Sun, Shan Wang, Jun Nan, Hai-Ling Yu, Yan La. N-palmitoylethanolamide attenuates negative emotions induced by morphine withdrawal in mice. Neuroscience letters. 2024-08-18. PMID:39154843. |
the findings indicate that pea mitigated anxiety and depression symptoms and reduced 5-hydroxytryptamine, noradrenaline, and dopamine levels in the hippocampus and prefrontal cortex. |
2024-08-18 |
2024-08-21 |
mouse |
| Guang-Nan Jin, Yu Wang, Yi-Ming Liu, Yu-Nan Lu, Jing-Mei Lu, Jing-He Wang, Jing-Wen Ma, Yan-Zhu Quan, Hong-Yan Gao, Yue-Xian Cui, Xiang Xu, Lian-Xun Pia. Arctiin Mitigates Neuronal Injury by Modulating the P2X7R/NLPR3 Inflammasome Signaling Pathway. Inflammation. 2024-08-17. PMID:39154088. |
building on previous findings that highlighted arc's capability to mitigate depression by dampening microglial hyperactivation and thereby reducing neuroinflammatory responses and cortical neuronal damage in mice, the current study delves deeper into arc's therapeutic potential by examining its impact on hippocampal neuronal damage in depression. |
2024-08-17 |
2024-08-20 |
mouse |
| Marco Toccaceli Blasi, Alba Rosa Alfano, Martina Salzillo, Simona Buscarnera, Valeria Raparelli, Matteo Cesari, Giuseppe Bruno, Marco Canevell. Sex-specific clinical and neurobiological correlates of fatigue in older adults. GeroScience. 2024-08-11. PMID:39129050. |
in the adjusted logistic regression model, more severe depression (or 1.64, 95% ci 1.18-2.28; p < 0.01) and lower mri hippocampus volumes (or 0.41, 95% ci 0.19-0.90; p = 0.03) resulted independently associated with fatigue in women, while higher frailty degrees (or 3.10, 95% ci 1.27-7.54 per 0.1 increase in a 39-item frailty index; p = 0.01) in men. |
2024-08-11 |
2024-08-14 |
human |
| Na Li, Ting Liu, Yu-Ye Wang, Tong Xu, Hu-Jiang Shi, Lei Chang, LiJuan Zh. Hippocampal HDAC5-mediated histone acetylation underlies stress susceptibility in mice exposed to chronic social defeat stress. Neuroscience. 2024-08-10. PMID:39127342. |
furthermore, hdac5 overexpression was sufficient to induce depression susceptibility following microdefeat stress, accompanied by a significant reduction in h4k12 level within the hippocampus of mice. |
2024-08-10 |
2024-08-13 |
mouse |
| Kathryn Y Manning, Aliza Jaffer, Catherine Lebe. Windows of opportunity: how age and sex shape the influence of prenatal depression on the child brain. Biological psychiatry. 2024-08-08. PMID:39117167. |
sex appears to play a key role in this relationship, with evidence of differential findings particularly in infants, with males showing smaller and females larger hippocampal and amygdala volumes following prenatal depression. |
2024-08-08 |
2024-08-12 |
Not clear |
| Guanghui Chen, Wenbin Zhang, Qiang Chen, Meixue Dong, Miao Liu, Gang Li. Geniposide exerts the antidepressant effect by affecting inflammation and glucose metabolism in a mouse model of depression. Chemico-biological interactions. 2024-08-04. PMID:39098740. |
herein, the aim of the present study was to employ non-target metabolomic platform of serum to investigate metabolic changes of depression mice and further verify in hippocampus for analyzing the antidepressant mechanism of geniposide. |
2024-08-04 |
2024-08-07 |
mouse |
| Guanghui Chen, Wenbin Zhang, Qiang Chen, Meixue Dong, Miao Liu, Gang Li. Geniposide exerts the antidepressant effect by affecting inflammation and glucose metabolism in a mouse model of depression. Chemico-biological interactions. 2024-08-04. PMID:39098740. |
the levels of arachidonic acid, lysopc, lactic acid and glucose 6-phosphate in hippocampus were consistent change with serum in depression mice. |
2024-08-04 |
2024-08-07 |
mouse |
| Li Wei, Xiaopeng Yu, Hui Chen, Yupeng D. The role of P2X4R in regulating CA1 hippocampal synaptic impairment in LPS-induced depression. Journal of affective disorders. 2024-07-17. PMID:39019229. |
the role of p2x4r in regulating ca1 hippocampal synaptic impairment in lps-induced depression. |
2024-07-17 |
2024-07-20 |
Not clear |
| Li Wei, Xiaopeng Yu, Hui Chen, Yupeng D. The role of P2X4R in regulating CA1 hippocampal synaptic impairment in LPS-induced depression. Journal of affective disorders. 2024-07-17. PMID:39019229. |
to study the role of the p2x4 receptor (p2x4r) in regulating hippocampal synaptic impairment in lipopolysaccharide (lps)-induced depression. |
2024-07-17 |
2024-07-20 |
Not clear |
| Ning-Xi Zeng, Xin Chen, Xiao-Yan Yang, De-Sheng Chen, Mei She. The therapeutic potential of curculigoside in poststroke depression: a focus on hippocampal neurogenesis and mitochondrial function. The Journal of pharmacy and pharmacology. 2024-07-16. PMID:39011997. |
the therapeutic potential of curculigoside in poststroke depression: a focus on hippocampal neurogenesis and mitochondrial function. |
2024-07-16 |
2024-07-18 |
Not clear |
| Masahito Ishiyama, Hitoshi Gotoh, Souichi Oe, Tadashi Nomura, Masaaki Kitada, Katsuhiko On. Glycogenolysis-Induced Astrocytic Serping1 Expression Regulates Neuroinflammatory Effects on Hippocampal neuron. Molecular neurobiology. 2024-07-10. PMID:38985256. |
recent findings have indicated that lps-induced activation of postnatal glial cells has led to alterations in synapse formation in hippocampal and cortical neurons, thereby resulting in a prolonged increased risk for seizure or depression. |
2024-07-10 |
2024-07-12 |
Not clear |
| Long Tao, Xiao-Xiao Li, Xin-Ru Tu, Rui Liu, Jia-Wen Xu, Yi-Li Lv, Yu-You Ya. Hippocampal Crhr1 conditional gene knockout ameliorated the depression-like behavior and pathological damage in male offspring mice caused by chronic stress during pregnancy. Behavioural brain research. 2024-07-05. PMID:38969017. |
numerous studies have demonstrated that chronic stress during pregnancy (csdp) can induce depression and hippocampal damage in offspring. |
2024-07-05 |
2024-07-08 |
mouse |