| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bente M Hofstra, Emmy E Hoeksema, Martien Jh Kas, Dineke S Verbee. Cross-species analysis uncovers the mitochondrial stress response in the hippocampus as a shared mechanism in mouse early life stress and human depression. Neurobiology of stress. vol 31. 2024-05-27. PMID:38800537. |
to better understand the core mechanisms underlying the development of depression, we used a cross-species design to investigate shared hippocampal pathophysiological mechanisms in mouse els and human depression. |
2024-05-27 |
2024-05-31 |
mouse |
| Bente M Hofstra, Emmy E Hoeksema, Martien Jh Kas, Dineke S Verbee. Cross-species analysis uncovers the mitochondrial stress response in the hippocampus as a shared mechanism in mouse early life stress and human depression. Neurobiology of stress. vol 31. 2024-05-27. PMID:38800537. |
our findings highlight the potential significance of the hippocampal mitochondrial stress response as a core mechanism underlying the development of depression. |
2024-05-27 |
2024-05-31 |
mouse |
| Lili Zhang, Yunshu Zhang, Wentao Guo, Qi Ma, Feng Zhang, Keqing Li, Qizhong Y. An Effect of Chronic Negative Stress on Hippocampal Structures and Functional Connectivity in Patients with Depressive Disorder. Neuropsychiatric disease and treatment. vol 20. 2024-05-21. PMID:38764745. |
here, we investigated the hippocampal structures and functional connectivity (fc) according to resting-state functional magnetic resonance imaging in patients with depression who underwent chronic negative stress. |
2024-05-21 |
2024-05-27 |
Not clear |
| Min Xiao, Peng-Fei Li, Xue-Jiao Ma, Xing-Ke Yan, Chong-Bing M. Research progress of acupuncture regulating ERK signaling pathway in the treatment of depression. Zhen ci yan jiu = Acupuncture research. vol 49. issue 5. 2024-05-19. PMID:38764124. |
future research could explore the relationship between the erk pathway and other pathways, investigate other brain regions besides the prefrontal cortex and hippocampus, examine differences in regulatory mechanisms between male and female patients, assess the effects of different acupuncture techniques on the erk pathway, and increase efforts to explore mechanism of synaptic plasticity regulation, so as to provide reference for the clinical application and mechanism sludy of acupuncture in depression treatment. |
2024-05-19 |
2024-05-27 |
Not clear |
| Jonas G Miller, Peter D Gluckman, Marielle V Fortier, Yap Seng Chong, Michael J Meaney, Ai Peng Tan, Ian H Gotli. Faster pace of hippocampal growth mediates the association between perinatal adversity and childhood depression. Developmental cognitive neuroscience. vol 67. 2024-05-18. PMID:38761439. |
faster pace of hippocampal growth mediates the association between perinatal adversity and childhood depression. |
2024-05-18 |
2024-05-27 |
Not clear |
| Marie-Elisabeth Burkart, Josephine Kurzke, Robert Jacobi, Jorge Vera, Frances M Ashcroft, Jens Eilers, Kristina Lippman. KATP channel mutation disrupts hippocampal network activity and nocturnal gamma shifts. Brain : a journal of neurology. 2024-05-15. PMID:38748482. |
we found, by performing electrophysiological experiments, that expressing the dend mutation kir6.2-v59m selectively in mouse pv-ins reduced intrinsic gamma frequency preference and short-term depression as well as disturbed cognition-associated gamma oscillations and hippocampal sharp waves. |
2024-05-15 |
2024-05-27 |
mouse |
| Jiao Cheng, Lin Yuan, Shuwen Yu, Bing Gu, Qian Luo, Xixi Wang, Yijing Zhao, Chengcheng Gai, Tingting Li, Weiyang Liu, Zhen Wang, Dexiang Liu, Roger C M Ho, Cyrus S H H. Programmed cell death factor 4-mediated hippocampal synaptic plasticity is involved in early life stress and susceptibility to depression. Behavioural brain research. vol 468. 2024-05-11. PMID:38723677. |
programmed cell death factor 4-mediated hippocampal synaptic plasticity is involved in early life stress and susceptibility to depression. |
2024-05-11 |
2024-05-27 |
mouse |
| Li Jingya, Linhong Song, Lu Lu, Qing Zhang, Weijun Zhan. Effect of Shenqi Jieyu formula on inflammatory response pathway in hippocampus of postpartum depression rats. Heliyon. vol 10. issue 9. 2024-05-10. PMID:38726147. |
effect of shenqi jieyu formula on inflammatory response pathway in hippocampus of postpartum depression rats. |
2024-05-10 |
2024-05-27 |
rat |
| Hu-Jiang Shi, Yi-Ren Xue, Hua Shao, Cheng Wei, Ting Liu, Jie He, Yu-Hao Yang, Hong-Mei Wang, Na Li, Si-Qiang Ren, Lei Chang, Zhen Wang, Li-Juan Zh. Hippocampal excitation-inhibition balance underlies the 5-HT2C receptor in modulating depressive behaviours. Brain : a journal of neurology. 2024-05-03. PMID:38701344. |
we now elucidate hippocampal excitation-inhibition (e/i) balance underlies the regulatory effects of 5-ht2cr in depression. |
2024-05-03 |
2024-05-06 |
Not clear |
| Sarah Nicolas, Sebastian Dohm-Hansen, Aonghus Lavelle, Thomaz F S Bastiaanssen, Jane A English, John F Cryan, Yvonne M Nola. Exercise mitigates a gut microbiota-mediated reduction in adult hippocampal neurogenesis and associated behaviours in rats. Translational psychiatry. vol 14. issue 1. 2024-04-24. PMID:38658547. |
lifestyle factors, especially exercise, impact the manifestation and progression of psychiatric and neurodegenerative disorders such as depression and alzheimer's disease, mediated by changes in hippocampal neuroplasticity. |
2024-04-24 |
2024-04-28 |
rat |
| You Yang, Dongyu Zhou, Su Min, Di Liu, Mou Zou, Chang Yu, Lihao Chen, Jia Huang, Ruiyang Hon. Ciprofol ameliorates ECS-induced learning and memory impairment by modulating aerobic glycolysis in the hippocampus of depressive-like rats. Pharmacology, biochemistry, and behavior. 2024-04-24. PMID:38657873. |
electroconvulsive shock (ecs) is utilized to treat depression but may cause learning/memory impairments, which may be ameliorated by anesthetics through the modulation of hippocampal synaptic plasticity. |
2024-04-24 |
2024-04-28 |
rat |
| Bandar N Aljafen, Ruwa Alneseyan, Taim Muayqil, Mashael O Alkhateeb, Mubarak M Aldosari, Aya Alsermani, Lujain Alnakhli, Renad Althomali, Razan Alnami, Ruba Alqahtani, Lama Ibrahim, Fawzi Babtai. Evaluating the prevalence and risk factors for depression in patients with temporal lobe epilepsy with hippocampal sclerosis: A cross-sectional multicenter study. Epilepsy & behavior : E&B. vol 154. 2024-04-18. PMID:38636108. |
evaluating the prevalence and risk factors for depression in patients with temporal lobe epilepsy with hippocampal sclerosis: a cross-sectional multicenter study. |
2024-04-18 |
2024-04-21 |
Not clear |
| Lisa Blum Moyse, Hugues Berr. A coupled neural field model for the standard consolidation theory. Journal of theoretical biology. 2024-04-15. PMID:38621583. |
this suggests that neurogenesis in the hippocampus and distance-dependent synaptic plasticity coupled to synaptic depression and spike frequency adaptation, are indeed critical neurobiological processes in memory consolidation. |
2024-04-15 |
2024-04-18 |
Not clear |
| Amine Bah. Serotonin transporter knockdown relieves depression-like behavior and ethanol-induced CPP in mice after chronic social defeat stress. Behavioural brain research. 2024-04-13. PMID:38614210. |
to further investigate this hypothesis, we used a lentiviral-mediated knockdown approach to examine the role of hippocampal sert knockdown in social defeat stress-elicited depression like behavior and ethanol-induced place preference (cpp). |
2024-04-13 |
2024-04-16 |
mouse |
| Qi Xu, Lihong Sun, Qing Chen, Cuicui Jiao, Yuan Wang, Hua Li, Jiaqian Xie, Fangfang Zhu, Jiangling Wang, Wen Zhang, Linghua Xie, Hui Wu, Zhiyi Zuo, Xinzhong Che. Gut microbiota dysbiosis contributes to depression-like behaviors via hippocampal NLRP3-mediated neuroinflammation in a postpartum depression mouse model. Brain, behavior, and immunity. 2024-04-10. PMID:38599497. |
gut microbiota dysbiosis contributes to depression-like behaviors via hippocampal nlrp3-mediated neuroinflammation in a postpartum depression mouse model. |
2024-04-10 |
2024-04-13 |
mouse |
| Jiuseng Zeng, Li Chen, Xi Peng, Fei Luan, Jingwen Hu, Zhiqiang Xie, Hongxiao Xie, Rong Liu, Haizhen Lv, Nan Zen. The anti-depression effect and potential mechanism of the petroleum ether fraction of CDB: Integrated network pharmacology and metabolomics. Heliyon. vol 10. issue 7. 2024-04-08. PMID:38586416. |
afterward, a cums mouse depression model was established and lc-ms-based untargeted hippocampal metabolomics was performed to identify differential metabolites, and related metabolic pathways. |
2024-04-08 |
2024-04-10 |
mouse |
| Zarah R Haniff, Mariia Bocharova, Tim Mantingh, James J Rucker, Latha Velayudhan, David M Taylor, Allan H Young, Dag Aarsland, Anthony C Vernon, Sandrine Thure. Psilocybin for dementia prevention? The potential role of psilocybin to alter mechanisms associated with major depression and neurodegenerative diseases. Pharmacology & therapeutics. 2024-04-07. PMID:38583670. |
in this narrative review, we focus on the evidence base for the effects of psilocybin on adult hippocampal neurogenesis and microglial form and function; which may suggest that psilocybin has the potential to modulate multiple mechanisms of action, and may have implications in altering the progression from major depression to dementia in those at risk. |
2024-04-07 |
2024-04-10 |
Not clear |
| Jun Chang, Huimin Yang, Xiaoqian Shan, Lan Zhao, Yujiao Li, Zhao Zhang, Joseph Kofi Abankwah, Mingxing Zhang, Yuhong Bian, Yi Gu. Bergamot essential oil improves CUMS-induced depression-like behaviour in rats by protecting the plasticity of hippocampal neurons. Journal of cellular and molecular medicine. vol 28. issue 8. 2024-03-30. PMID:38553964. |
collectively, inhaled beo mitigates depression by protecting the plasticity of hippocampal neurons, hence, providing novel insights into treatment of depression. |
2024-03-30 |
2024-04-01 |
rat |
| Yangdong Zhang, Haiyang Wang, Lanxiang Liu, Xiaolong Mo, Dian He, Xueyi Chen, Rui Xiao, Qisheng Cheng, Madiha Fatima, Yamei Du, Peng Xi. Maternal Separation Regulates Sensitivity of Stress-Induced Depression in Mice by Affecting Hippocampal Metabolism. Physiology & behavior. 2024-03-29. PMID:38552706. |
maternal separation regulates sensitivity of stress-induced depression in mice by affecting hippocampal metabolism. |
2024-03-29 |
2024-04-01 |
mouse |
| Xiang-Ming Cai, Xiao-Yu Sun, Rui Li, Pei-Juan Wang, Jian-Cheng Qi, Yu-Xin Ge, Lei Yan. The hippocampal Salt-Inducible Kinase 2-CREB-Regulated Transcription Co-activator 1 system mediates the antidepressant actions of paroxetine in mice. Behavioural brain research. 2024-03-29. PMID:38552744. |
the hippocampal salt-inducible kinase 2 (sik2)-creb-regulated transcription co-activator 1 (crtc1) system has been demonstrated to participate in not only the pathogenesis of depression but also the antidepressant mechanisms of several antidepressant medications including fluoxetine, paroxetine, and mirtazapine. |
2024-03-29 |
2024-04-01 |
mouse |