| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marta Díaz González, Assaf Buberman, Miguel Morales, Isidro Ferrer, Shira Knaf. Aberrant Synaptic PTEN in Symptomatic Alzheimer's Patients May Link Synaptic Depression to Network Failure. Frontiers in synaptic neuroscience. vol 13. 2021-05-30. PMID:34045952. |
there is now evidence from ad models that aβ provokes this shift toward synaptic depression by triggering the access to and accumulation of pten in the postsynaptic terminal of hippocampal neurons. |
2021-05-30 |
2023-08-13 |
human |
| Paul J Lucassen, Carlos P Fitzsimons, Evgenia Salta, Mirjana Maletic-Savati. Adult neurogenesis, human after all (again): Classic, optimized, and future approaches. Behavioural brain research. vol 381. 2021-05-26. PMID:31899214. |
we further discuss novel approaches, like single-cell/nucleus sequencing and magnetic resonance spectroscopy, that will help advance the study of human neurogenesis to its fullest potential - understanding its contribution to human hippocampal functions and related disorders like depression and dementia. |
2021-05-26 |
2023-08-13 |
human |
| SangJin Im, Jeonghwan Lee, Siekyeong Ki. Preliminary Comparison of Subcortical Structures in Elderly Subclinical Depression: Structural Analysis with 3T MRI. Experimental neurobiology. vol 30. issue 2. 2021-05-25. PMID:33972469. |
structural analysis using probabilistic tractography indicated that the connection strength between left nucleus accumbens-right hippocampus, and right thalamus-right caudate was higher in the control group than the subclinical depression group. |
2021-05-25 |
2023-08-13 |
human |
| Ru Liu, Xin-Miao Wu, Xue He, Run-Zhu Wang, Xiao-Yu Yin, Feng Zhou, Mu-Huo Ji, Jin-Chun She. Contribution of DNA methyltransferases to spared nerve injury induced depression partially through epigenetically repressing Bdnf in hippocampus: Reversal by ketamine. Pharmacology, biochemistry, and behavior. vol 200. 2021-05-24. PMID:33245982. |
contribution of dna methyltransferases to spared nerve injury induced depression partially through epigenetically repressing bdnf in hippocampus: reversal by ketamine. |
2021-05-24 |
2023-08-13 |
rat |
| Ru Liu, Xin-Miao Wu, Xue He, Run-Zhu Wang, Xiao-Yu Yin, Feng Zhou, Mu-Huo Ji, Jin-Chun She. Contribution of DNA methyltransferases to spared nerve injury induced depression partially through epigenetically repressing Bdnf in hippocampus: Reversal by ketamine. Pharmacology, biochemistry, and behavior. vol 200. 2021-05-24. PMID:33245982. |
methylation changes of brain-derived neurotrophic factor (bdnf) in the hippocampus are critical for neuropathic pain and depression. |
2021-05-24 |
2023-08-13 |
rat |
| Ru Liu, Xin-Miao Wu, Xue He, Run-Zhu Wang, Xiao-Yu Yin, Feng Zhou, Mu-Huo Ji, Jin-Chun She. Contribution of DNA methyltransferases to spared nerve injury induced depression partially through epigenetically repressing Bdnf in hippocampus: Reversal by ketamine. Pharmacology, biochemistry, and behavior. vol 200. 2021-05-24. PMID:33245982. |
thus, we hypothesized that dnmts are required for depression genesis, probably by repressing hippocampus bdnf gene expression in rats with neuropathic pain, which can be rescued by ketamine. |
2021-05-24 |
2023-08-13 |
rat |
| Ru Liu, Xin-Miao Wu, Xue He, Run-Zhu Wang, Xiao-Yu Yin, Feng Zhou, Mu-Huo Ji, Jin-Chun She. Contribution of DNA methyltransferases to spared nerve injury induced depression partially through epigenetically repressing Bdnf in hippocampus: Reversal by ketamine. Pharmacology, biochemistry, and behavior. vol 200. 2021-05-24. PMID:33245982. |
sni upregulated dnmts and downregulated bdnf and exon i in the hippocampus and induced depression behaviors, whereas blocking the upregulation of dnmts with rg108 alleviated sni-induced depression by up-regulation of the expression of bdnf and exon i. |
2021-05-24 |
2023-08-13 |
rat |
| Yuqi Cai, Nourhan M Elsayed, Deanna M Barc. Contributions from resting state functional connectivity and familial risk to early adolescent-onset MDD: Results from the Adolescent Brain Cognitive Development study. Journal of affective disorders. vol 287. 2021-05-21. PMID:33799042. |
we examined the relationships between familial risk for depression and alterations to resting state functional connectivity (rsfc) within the default mode network (wdmn) and between the dmn and the left/right hippocampus (dmn-lhipp/dmn-rhipp) to the risk for early adolescent mdd onset. |
2021-05-21 |
2023-08-13 |
Not clear |
| Nathália Stela Visoná de Figueiredo, Larissa Botelho Gaça, Idaiane Batista Assunção-Leme, Lenon Mazetto, Maria Teresa Fernandes Castilho Garcia, Gabriel Barbosa Sandim, Neide Barreira Alonso, Ricardo Silva Centeno, Gerardo Maria de Araújo Filho, Andrea Parolin Jackowski, Henrique Carrete Júnior, Elza Márcia Targas Yacubia. A pioneering FreeSurfer volumetric study of a series of patients with mesial temporal lobe epilepsy and hippocampal sclerosis with comorbid depression. Psychiatry research. Neuroimaging. vol 311. 2021-05-20. PMID:33836383. |
a pioneering freesurfer volumetric study of a series of patients with mesial temporal lobe epilepsy and hippocampal sclerosis with comorbid depression. |
2021-05-20 |
2023-08-13 |
Not clear |
| Nathália Stela Visoná de Figueiredo, Larissa Botelho Gaça, Idaiane Batista Assunção-Leme, Lenon Mazetto, Maria Teresa Fernandes Castilho Garcia, Gabriel Barbosa Sandim, Neide Barreira Alonso, Ricardo Silva Centeno, Gerardo Maria de Araújo Filho, Andrea Parolin Jackowski, Henrique Carrete Júnior, Elza Márcia Targas Yacubia. A pioneering FreeSurfer volumetric study of a series of patients with mesial temporal lobe epilepsy and hippocampal sclerosis with comorbid depression. Psychiatry research. Neuroimaging. vol 311. 2021-05-20. PMID:33836383. |
depression is the most frequent psychiatric comorbidity in patients with mesial temporal lobe epilepsy (mtle) and hippocampal sclerosis (hs). |
2021-05-20 |
2023-08-13 |
Not clear |
| Eduardo H Sanchez-Mendoza, Santiago Camblor-Perujo, Luiza Martins Nascentes-Melo, Egor Dzyubenko, Michael Fleischer, Tayana Silva de Carvalho, Linda-Isabell Schmitt, Markus Leo, Tim Hagenacker, Arne Herring, Kathy Keyvani, Sujoy Bera, Natalia Kononenko, Christoph Kleinschnitz, Dirk M Herman. Compromised Hippocampal Neuroplasticity in the Interferon-α and Toll-like Receptor-3 Activation-Induced Mouse Depression Model. Molecular neurobiology. vol 57. issue 7. 2021-05-19. PMID:32504419. |
compromised hippocampal neuroplasticity in the interferon-α and toll-like receptor-3 activation-induced mouse depression model. |
2021-05-19 |
2023-08-13 |
mouse |
| R Asaad Baksh, Craig W Ritchie, Graciela Muniz Terrera, Joanna Norton, Vanessa Raymont, Karen Ritchi. The association between anxiety disorders and hippocampal volume in older adults. Psychology and aging. vol 36. issue 2. 2021-05-19. PMID:33661669. |
cross-sectional analyses adjusted for age, educational level, gender, mini-mental state examination scores, national adult reading test scores, whole brain volume and depression found that a diagnosis of generalized anxiety disorder was positively associated with larger hippocampal volume. |
2021-05-19 |
2023-08-13 |
Not clear |
| Karina Maciak, Angela Dziedzic, Elzbieta Miller, Joanna Saluk-Bija. miR-155 as an Important Regulator of Multiple Sclerosis Pathogenesis. A Review. International journal of molecular sciences. vol 22. issue 9. 2021-05-19. PMID:33919306. |
recent studies revealed the role of mir-155 in regulating anxiety, stress, inflammation in the hippocampus, and treatment-resistant depression. |
2021-05-19 |
2023-08-13 |
Not clear |
| Chris Greene, Nicole Hanley, Matthew Campbel. Blood-brain barrier associated tight junction disruption is a hallmark feature of major psychiatric disorders. Translational psychiatry. vol 10. issue 1. 2021-05-18. PMID:33139732. |
using immunohistochemistry and qrt-pcr, we show that the expression of claudin-5 is reduced in the hippocampus of individuals diagnosed with major depression or schizophrenia. |
2021-05-18 |
2023-08-13 |
human |
| Brunno Rocha Levone, Gerard M Moloney, John F Cryan, Olivia F O'Lear. Specific sub-regions along the longitudinal axis of the hippocampus mediate antidepressant-like behavioral effects. Neurobiology of stress. vol 14. 2021-05-18. PMID:33997156. |
there is increasing attention on the functional segregation of the hippocampus into a dorsal region (dhi) predominantly involved in spatial learning and memory, and a ventral region (vhi) which regulates anxiety, a symptom often co-morbid with depression. |
2021-05-18 |
2023-08-13 |
mouse |
| Ana R Machado-Santos, Nuno D Alves, Bruna Araújo, Joana S Correia, Patrícia Patrício, António Mateus-Pinheiro, Eduardo Loureiro-Campos, João M Bessa, Nuno Sousa, Luísa Pint. Astrocytic plasticity at the dorsal dentate gyrus on an animal model of recurrent depression. Neuroscience. vol 454. 2021-05-14. PMID:31747562. |
both human postmortem studies in brain samples from patients diagnosed with major depressive disorder and from animal models of depression reported numerical and morphological astrocytic changes specifically in the hippocampus. |
2021-05-14 |
2023-08-13 |
human |
| H Acosta, K Kantojärvi, N Hashempour, J Pelto, N M Scheinin, S J Lehtola, J D Lewis, V S Fonov, D L Collins, A Evans, R Parkkola, T Lähdesmäki, J Saunavaara, L Karlsson, H Merisaari, T Paunio, H Karlsson, J J Tuular. Partial Support for an Interaction Between a Polygenic Risk Score for Major Depressive Disorder and Prenatal Maternal Depressive Symptoms on Infant Right Amygdalar Volumes. Cerebral cortex (New York, N.Y. : 1991). vol 30. issue 12. 2021-05-14. PMID:32676648. |
we investigated in 105 finnish mother-infant dyads (44 female, 11-54 days old) how offspring prs-mdd interacts with prenatal maternal depressive symptoms (edinburgh postnatal depression scale, gestational weeks 14, 24, 34) on infant amygdalar and hippocampal volumes. |
2021-05-14 |
2023-08-13 |
Not clear |
| Vasilios Kafetzopoulos, Nikolaos Kokras, Nuno Sousa, Katerina Antoniou, Ioannis Sotiropoulos, Christina Dall. Nucleus Reuniens Lesion and Antidepressant Treatment Prevent Hippocampal Neurostructural Alterations Induced by Chronic Mild Stress in Male Rats. Neuroscience. vol 454. 2021-05-14. PMID:32828941. |
the present findings highlight the importance of hippocampal-prefrontal cortex communication in chronic stress effects on hippocampal neuroplasticity and contribute to the elucidation of the role of re in neurostructural changes underlying stress-driven depression and its treatment. |
2021-05-14 |
2023-08-13 |
rat |
| Zeljka Brkic, Ana Zivanovic, Miroslav Adzi. Sex-specific Effects of Lipopolysaccharide on Hippocampal Mitochondrial Processes in Neuroinflammatory Model of Depression. Neuroscience. vol 451. 2021-05-14. PMID:33039525. |
sex-specific effects of lipopolysaccharide on hippocampal mitochondrial processes in neuroinflammatory model of depression. |
2021-05-14 |
2023-08-13 |
rat |
| b' Ivana Peri\\xc4\\x87, Victor Costina, Peter Findeisen, Peter Gass, Dragana Filipovi\\xc4\\x8. Tianeptine Enhances Energy-related Processes in the Hippocampal Non-synaptic Mitochondria in a Rat Model of Depression. Neuroscience. vol 451. 2021-05-14. PMID:33065230.' |
tianeptine enhances energy-related processes in the hippocampal non-synaptic mitochondria in a rat model of depression. |
2021-05-14 |
2023-08-13 |
rat |