| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ronald S Duman, Satoshi Deyama, Manoela Viar Fogaç. Role of BDNF in the pathophysiology and treatment of depression: Activity-dependent effects distinguish rapid-acting antidepressants. The European journal of neuroscience. vol 53. issue 1. 2021-06-28. PMID:31811669. |
here, we review the literature demonstrating that exposure to stress and depression decreases bdnf expression in the hippocampus and pfc and conversely that antidepressant treatment can up-regulate bdnf in the adult brain and reverse the effects of stress. |
2021-06-28 |
2023-08-13 |
Not clear |
| Yue Li, Yanmin Luo, Jing Tang, Xin Liang, Jin Wang, Qian Xiao, Peilin Zhu, Kai Xiao, Lin Jiang, Xiaoyun Dou, Chunxia Huang, Yuhan Xie, Yong Tan. The positive effects of running exercise on hippocampal astrocytes in a rat model of depression. Translational psychiatry. vol 11. issue 1. 2021-06-28. PMID:33526783. |
the positive effects of running exercise on hippocampal astrocytes in a rat model of depression. |
2021-06-28 |
2023-08-13 |
rat |
| Yue Li, Yanmin Luo, Jing Tang, Xin Liang, Jin Wang, Qian Xiao, Peilin Zhu, Kai Xiao, Lin Jiang, Xiaoyun Dou, Chunxia Huang, Yuhan Xie, Yong Tan. The positive effects of running exercise on hippocampal astrocytes in a rat model of depression. Translational psychiatry. vol 11. issue 1. 2021-06-28. PMID:33526783. |
mounting evidence suggests that changes in astrocyte number in the hippocampus are closely associated with depression. |
2021-06-28 |
2023-08-13 |
rat |
| Yue Li, Yanmin Luo, Jing Tang, Xin Liang, Jin Wang, Qian Xiao, Peilin Zhu, Kai Xiao, Lin Jiang, Xiaoyun Dou, Chunxia Huang, Yuhan Xie, Yong Tan. The positive effects of running exercise on hippocampal astrocytes in a rat model of depression. Translational psychiatry. vol 11. issue 1. 2021-06-28. PMID:33526783. |
however, the effects of running exercise on astrocytes in the hippocampus of depression have not been investigated. |
2021-06-28 |
2023-08-13 |
rat |
| Lucien Gyger, Francesca Regen, Cristina Ramponi, Renaud Marquis, Jean-Frederic Mall, Kevin Swierkosz-Lenart, Armin von Gunten, Nicolas Toni, Ferath Kherif, Isabella Heuser, Bogdan Dragansk. Gradient of electro-convulsive therapy's antidepressant effects along the longitudinal hippocampal axis. Translational psychiatry. vol 11. issue 1. 2021-06-28. PMID:33782387. |
we interpret our findings confined to the anterior hippocampus and amygdala as additional evidence of the regional specific impact of ect that unfolds its beneficial effect on depression via the "limbic" system. |
2021-06-28 |
2023-08-13 |
Not clear |
| Anna Höflich, Christoph Kraus, Ruth M Pfeiffer, Rene Seiger, Dan Rujescu, Carlos A Zarate, Siegfried Kasper, Dietmar Winkler, Rupert Lanzenberge. Translating the immediate effects of S-Ketamine using hippocampal subfield analysis in healthy subjects-results of a randomized controlled trial. Translational psychiatry. vol 11. issue 1. 2021-06-28. PMID:33795646. |
the results translate previous findings from animal models of depression showing that ketamine has pro-neuroplastic effects on hippocampal structures and underscore the importance of the hippocampus as a key region in ketamine's mechanism of action. |
2021-06-28 |
2023-08-13 |
human |
| Wei-Yang Chen, Hu Chen, Kana Hamada, Eleonora Gatta, Ying Chen, Huaibo Zhang, Jenny Drnevich, Harish R Krishnan, Mark Maienschein-Cline, Dennis R Grayson, Subhash C Pandey, Amy W Lase. Transcriptomics identifies STAT3 as a key regulator of hippocampal gene expression and anhedonia during withdrawal from chronic alcohol exposure. Translational psychiatry. vol 11. issue 1. 2021-06-28. PMID:34016951. |
these results demonstrate activation of stat3 signaling in the hippocampus during alcohol withdrawal in rats and in human aud subjects, and suggest that stat3 could be a therapeutic target for reducing comorbid aud and depression. |
2021-06-28 |
2023-08-13 |
human |
| Matthew R J Vandermeer, Pan Liu, Ola Mohamed Ali, Andrew R Daoust, Marc F Joanisse, Deanna M Barch, Elizabeth P Hayde. Orbitofrontal cortex grey matter volume is related to children's depressive symptoms. NeuroImage. Clinical. vol 28. 2021-06-25. PMID:32889399. |
adults with a history of depression show distinct patterns of grey matter volume (gmv) in frontal cortical (e.g., prefrontal cortex, orbitofrontal cortex) and limbic (e.g., anterior cingulate, amygdala, hippocampus, dorsal striatum) structures, regions relevant to the processing and regulation of reward, which is impaired in the context of depression. |
2021-06-25 |
2023-08-13 |
Not clear |
| Bo Zhang, Shouliang Qi, Shuang Liu, Xiaoya Liu, Xinhua Wei, Dong Min. Altered spontaneous neural activity in the precuneus, middle and superior frontal gyri, and hippocampus in college students with subclinical depression. BMC psychiatry. vol 21. issue 1. 2021-06-25. PMID:34074266. |
altered spontaneous neural activity in the precuneus, middle and superior frontal gyri, and hippocampus in college students with subclinical depression. |
2021-06-25 |
2023-08-13 |
Not clear |
| Ichrak Drissi, Chloé Deschamps, Grégory Fouquet, Rachel Alary, Stéphane Peineau, Philippe Gosset, Harold Sueur, Ingrid Marcq, Véronique Debuysscher, Mickael Naassila, Catherine Vilpoux, Olivier Pierrefich. Memory and plasticity impairment after binge drinking in adolescent rat hippocampus: GluN2A/GluN2B NMDA receptor subunits imbalance through HDAC2. Addiction biology. vol 25. issue 3. 2021-06-24. PMID:31056842. |
previously, we reported that two binge-like exposures to etoh (3 g/kg, ip, 9 h apart) in adolescent rats abolished long-term synaptic depression (ltd) in hippocampus slices, induced learning deficits, and increased n-methyl-d-aspartate (nmda) receptor signaling through its glun2b subunit after 48 hours. |
2021-06-24 |
2023-08-13 |
rat |
| Yingjie Qin, Xin Tong, Wei Li, Le Zhang, Yingying Zhang, Xiuli Li, Jing Yang, Kun Qin, Du Lei, Qiyong Gong, Dong Zhou, Dongmei A. Divergent Anatomical Correlates and Functional Network Connectivity Patterns in Temporal Lobe Epilepsy with and Without Depression. Brain topography. vol 34. issue 4. 2021-06-24. PMID:33973138. |
meanwhile, compared to hcs, tle-n showed smaller hcvs, tle-d and tle-n showed smaller gmv in the medial orbital frontal gyrus and right hippocampus and hippocampal gyrus, possibly implying predisposition of epileptic activities to co-morbid depression. |
2021-06-24 |
2023-08-13 |
Not clear |
| Songji Li, Wenyu Cao, Shifen Zhou, Minhui Ma, Wenjuan Zhang, Fang Li, Changqi L. Expression of Cntn1 is regulated by stress and associated with anxiety and depression phenotypes. Brain, behavior, and immunity. vol 95. 2021-06-23. PMID:33737174. |
collectively, our results identified cntn1 as a novel risk gene involved in regulating anxiety and depression via functional actions in the hippocampus that is correlated with microglial activation or phagocytosis and reduced hippocampal immature neurons. |
2021-06-23 |
2023-08-13 |
mouse |
| Hui Yang, Jia Ling, Pan Meng, Jian Liu, Xiaoyuan Lin, Wei Li, Yuhong Wan. Activation of Hippocampal IR/IRS-1 Signaling Contributes to the Treatment with Zuogui Jiangtang Jieyu Decoction on the Diabetes-Related Depression. Evidence-based complementary and alternative medicine : eCAM. vol 2021. 2021-06-22. PMID:34149862. |
activation of hippocampal ir/irs-1 signaling contributes to the treatment with zuogui jiangtang jieyu decoction on the diabetes-related depression. |
2021-06-22 |
2023-08-13 |
rat |
| P N Suresh Kumar, Abhay Sharma, Chittaranjan Andrad. A pilot, open-label investigation of the efficacy of glucosamine for the treatment of major depression. Asian journal of psychiatry. vol 52. 2021-06-21. PMID:32388446. |
glucosamine hydrochloride normalizes gaba antagonist- and social defeat-induced behavioral alterations and upregulation of immune response genes in drosophila and mice, respectively, increases hippocampal neurogenesis in mice, and demonstrates efficacy in murine behavioral models of depression. |
2021-06-21 |
2023-08-13 |
mouse |
| Katherina A Lebedeva, Josh Allen, Erin Y Kulhawy, Hector J Caruncho, Lisa E Kalynchu. Cyclical administration of corticosterone results in aggravation of depression-like behaviors and accompanying downregulations in reelin in an animal model of chronic stress relevant to human recurrent depression. Physiology & behavior. vol 224. 2021-06-21. PMID:32663551. |
after behavioral testing, the rats were sacrificed for immunohistochemical analyses of the extracellular matrix protein reelin, which is involved in regulating neural plasticity and is decreased in the hippocampus of depression patients. |
2021-06-21 |
2023-08-13 |
human |
| Fahime Zavvari, Arezo Nahavand. Fluoxetine increases hippocampal neural survival by improving axonal transport in stress-induced model of depression male rats. Physiology & behavior. vol 227. 2021-06-21. PMID:32828030. |
fluoxetine increases hippocampal neural survival by improving axonal transport in stress-induced model of depression male rats. |
2021-06-21 |
2023-08-13 |
rat |
| Fahime Zavvari, Arezo Nahavand. Fluoxetine increases hippocampal neural survival by improving axonal transport in stress-induced model of depression male rats. Physiology & behavior. vol 227. 2021-06-21. PMID:32828030. |
this study aimed to investigate the effects of chronic fluoxetine treatment on axonal transport in the hippocampus of rat stress-induced model of depression. |
2021-06-21 |
2023-08-13 |
rat |
| Jonika Tannous, Beata R Godlewska, Vaishali Tirumalaraju, Jair C Soares, Phil J Cowen, Sudhakar Selvara. Stress, inflammation and hippocampal subfields in depression: A 7 Tesla MRI Study. Translational psychiatry. vol 10. issue 1. 2021-06-18. PMID:32098947. |
stress, inflammation and hippocampal subfields in depression: a 7 tesla mri study. |
2021-06-18 |
2023-08-13 |
human |
| Bhedita J Seewoo, Lauren A Hennessy, Kirk W Feindel, Sarah J Etherington, Paul E Croarkin, Jennifer Rodge. Validation of Chronic Restraint Stress Model in Young Adult Rats for the Study of Depression Using Longitudinal Multimodal MR Imaging. eNeuro. vol 7. issue 4. 2021-06-18. PMID:32669346. |
prior research suggests that the neurobiological underpinnings of depression include aberrant brain functional connectivity, neurometabolite levels, and hippocampal volume. |
2021-06-18 |
2023-08-13 |
human |
| Bhedita J Seewoo, Lauren A Hennessy, Kirk W Feindel, Sarah J Etherington, Paul E Croarkin, Jennifer Rodge. Validation of Chronic Restraint Stress Model in Young Adult Rats for the Study of Depression Using Longitudinal Multimodal MR Imaging. eNeuro. vol 7. issue 4. 2021-06-18. PMID:32669346. |
chronic restraint stress (crs) depression model in rats has been shown to elicit behavioral, gene expression, protein, functional connectivity, and hippocampal volume changes similar to those in human depression. |
2021-06-18 |
2023-08-13 |
human |