| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Thiraphat Saengmearnuparp, Bannakij Lojanapiwat, Nipon Chattipakorn, Siriporn Chattipakor. The connection of 5-alpha reductase inhibitors to the development of depression. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 143. 2021-10-13. PMID:34479019. |
the potential mechanisms that link 5-aris and depression include alteration in neuroactive steroids, dopaminergic dysfunction, reduced hippocampal neurogenesis, increased neuroinflammation, alteration of the hpa axis, and epigenetic modifications. |
2021-10-13 |
2023-08-13 |
Not clear |
| Bo Cao, Qinghua Luo, Yixiao Fu, Lian Du, Tian Qiu, Xiangying Yang, Xiaolu Chen, Qibin Chen, Jair C Soares, Raymond Y Cho, Xiang Yang Zhang, Haitang Qi. Author Correction: Predicting individual responses to the electroconvulsive therapy with hippocampal subfield volumes in major depression disorder. Scientific reports. vol 10. issue 1. 2021-10-12. PMID:33097754. |
author correction: predicting individual responses to the electroconvulsive therapy with hippocampal subfield volumes in major depression disorder. |
2021-10-12 |
2023-08-13 |
Not clear |
| Shiyang Huang, Can Zheng, Guoguang Xie, Zhanming Song, Pingzhang Wang, Yun Bai, Dixin Chen, Yan Zhang, Ping Lv, Weiwei Liang, Shaoping She, Qingqing Li, Zhongtian Liu, Yun Wang, Guo-Gang Xing, Ying Wan. FAM19A5/TAFA5, a novel neurokine, plays a crucial role in depressive-like and spatial memory-related behaviors in mice. Molecular psychiatry. vol 26. issue 6. 2021-10-11. PMID:32317715. |
taken together, our results revealed for the first time that fam19a5 plays a key role in the regulation of depression and spatial cognition in the hippocampus. |
2021-10-11 |
2023-08-13 |
mouse |
| Zhen Kang, Haimin Ye, Tao Chen, Peng Zhan. Effect of Electroacupuncture at Siguan Acupoints on Expression of BDNF and TrkB Proteins in the Hippocampus of Post-Stroke Depression Rats. Journal of molecular neuroscience : MN. vol 71. issue 10. 2021-10-11. PMID:34041688. |
effect of electroacupuncture at siguan acupoints on expression of bdnf and trkb proteins in the hippocampus of post-stroke depression rats. |
2021-10-11 |
2023-08-13 |
rat |
| Zhen Kang, Haimin Ye, Tao Chen, Peng Zhan. Effect of Electroacupuncture at Siguan Acupoints on Expression of BDNF and TrkB Proteins in the Hippocampus of Post-Stroke Depression Rats. Journal of molecular neuroscience : MN. vol 71. issue 10. 2021-10-11. PMID:34041688. |
to study the effect of electroacupuncture at the siguan acupoints on the expression of hippocampal brain-derived neurotrophic factor (bdnf) and tyrosine receptor kinase b (trkb) in post-stroke depression (psd) rats, in order to explore its possible mechanism fifty specific pathogen-free (spf)-grade adult male sprague-dawley (sd) rats were randomly divided into a blank group, stroke group, psd group, siguan acupoint group and fluoxetine group according to the random number method. |
2021-10-11 |
2023-08-13 |
rat |
| Zhen Kang, Haimin Ye, Tao Chen, Peng Zhan. Correction to: Effect of Electroacupuncture at Siguan Acupoints on Expression of BDNF and TrkB Proteins in the Hippocampus of Post-Stroke Depression Rats. Journal of molecular neuroscience : MN. vol 71. issue 10. 2021-10-11. PMID:34184198. |
correction to: effect of electroacupuncture at siguan acupoints on expression of bdnf and trkb proteins in the hippocampus of post-stroke depression rats. |
2021-10-11 |
2023-08-13 |
rat |
| Kai Xiao, Yanmin Luo, Xin Liang, Jing Tang, Jin Wang, Qian Xiao, Yingqiang Qi, Yue Li, Peilin Zhu, Hao Yang, Yuhan Xie, Hong Wu, Yong Tan. Beneficial effects of running exercise on hippocampal microglia and neuroinflammation in chronic unpredictable stress-induced depression model rats. Translational psychiatry. vol 11. issue 1. 2021-10-11. PMID:34489395. |
beneficial effects of running exercise on hippocampal microglia and neuroinflammation in chronic unpredictable stress-induced depression model rats. |
2021-10-11 |
2023-08-13 |
rat |
| Kai Xiao, Yanmin Luo, Xin Liang, Jing Tang, Jin Wang, Qian Xiao, Yingqiang Qi, Yue Li, Peilin Zhu, Hao Yang, Yuhan Xie, Hong Wu, Yong Tan. Beneficial effects of running exercise on hippocampal microglia and neuroinflammation in chronic unpredictable stress-induced depression model rats. Translational psychiatry. vol 11. issue 1. 2021-10-11. PMID:34489395. |
however, the effects of running exercise on hippocampal neuroinflammation and the number and activation of microglia in depression have not been studied. |
2021-10-11 |
2023-08-13 |
rat |
| Priyanka Pahwa, Tanveer Singh, Rajesh Kumar Goe. Anticonvulsant Effect of Asparagus racemosus Willd. in a Mouse Model of Catamenial Epilepsy. Neurochemical research. 2021-10-08. PMID:34623565. |
four hours after ptz, animals were assessed for depression like phenotypes followed by euthanasia and separation of brain parts (cortex and hippocampus). |
2021-10-08 |
2023-08-13 |
mouse |
| Júnia L de Deus, Mateus R Amorim, Aline B Ribeiro, Procópio C G Barcellos-Filho, César C Ceballos, Luiz Guilherme S Branco, Alexandra O S Cunha, Ricardo M Leã. Loss of Brain-Derived Neurotrophic Factor Mediates Inhibition of Hippocampal Long-Term Potentiation by High-Intensity Sound. Cellular and molecular neurobiology. vol 41. issue 4. 2021-10-06. PMID:32445041. |
our results indicate that depression of hippocampal bdnf mediates the inhibition of ltp produced by high-intensity sound stimulation. |
2021-10-06 |
2023-08-13 |
rat |
| Jie Shen, Ping Zhang, Ye Li, Cuiqin Fan, Tian Lan, Wenjing Wang, Shu Yan Y. Neuroprotective effects of microRNA-211-5p on chronic stress-induced neuronal apoptosis and depression-like behaviours. Journal of cellular and molecular medicine. vol 25. issue 14. 2021-10-05. PMID:34121317. |
in the present study, we screened mirna expression profiles in the ca1 hippocampus of a rat model of depression and found that a specific mirna, microrna-211-5p, was significantly down-regulated in depressed rats. |
2021-10-05 |
2023-08-13 |
rat |
| Shangyan Gao, Xueling Zhang, Hui Xu, Dongjin Miao, Jiaoni Qian, Zhonghua Wu, Weihua Sh. Promoting the hippocampal PPARα expression participates in the antidepressant mechanism of reboxetine, a selective norepinephrine reuptake inhibitor. Behavioural brain research. vol 416. 2021-10-05. PMID:34416301. |
previous reports have demonstrated the role of hippocampal pparα in the pathophysiology of depression. |
2021-10-05 |
2023-08-13 |
Not clear |
| Toshinori Yoshioka, Daisuke Yamada, Riho Kobayashi, Eri Segi-Nishida, Akiyoshi Saito. Chronic vicarious social defeat stress attenuates new-born neuronal cell survival in mouse hippocampus. Behavioural brain research. vol 416. 2021-10-05. PMID:34416303. |
these results demonstrate that emotional stress in the vicarious social defeat stress paradigm influences neuronal cell survival in the hippocampus, which reinforces its validity as an animal model of depression. |
2021-10-05 |
2023-08-13 |
mouse |
| Ali Mohammadkhanizadeh, Farnaz Nikbakh. Investigating the potential mechanisms of depression induced-by COVID-19 infection in patients. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 91. 2021-10-04. PMID:34373041. |
the reasons for depression in infected patients may be due to social and pathological factors including social quarantine, economic problems, stress, changes in the hpa axis, inflammation due to the entry of proinflammatory cytokines into the cns, production of inflammatory cytokines by microglia, mitochondrial disorders, damage to the hippocampus, and malnutrition. |
2021-10-04 |
2023-08-13 |
Not clear |
| Cheng Zhu, Li Hui, Ke Zheng, Linjing Liu, Jiahong Liu, Wei L. Silencing of RGS2 enhances hippocampal neuron regeneration and rescues depression-like behavioral impairments through activation of cAMP pathway. Brain research. vol 1746. 2021-10-01. PMID:32679115. |
collectively, our study uncovered the role of rgs2-dependent camp pathway in regulation of cognitive impairment and hippocampal neuron regeneration in depression-like behaviors of mice, which may be a potential therapeutic target for impairments and symptoms associated with depression. |
2021-10-01 |
2023-08-13 |
mouse |
| Mu-N Liu, Jakobus Gerick Pantouw, Kai-Chun Yang, Li-Yu Hu, Ying-Jay Liou, Jiing-Feng Lirng, Yuan-Hwa Cho. Sub-regional hippocampal volumes in first-episode drug-naïve major depression disorder. Neuroscience letters. vol 763. 2021-10-01. PMID:34416346. |
sub-regional hippocampal volumes in first-episode drug-naïve major depression disorder. |
2021-10-01 |
2023-08-13 |
Not clear |
| Yanlin Tao, Zhejun Xie, Jiachen Shi, Rongliwen Ou, Hui Wu, Hailian Shi, Fei Huang, Xiaojun W. Hippocampal mRNA expression profiling in mice exposed to chronic unpredictable mild stress. Brain research bulletin. vol 162. 2021-09-29. PMID:32534010. |
depression is a state of low mood and aversion to activity, affecting a person's thoughts, behavior, motivation, feelings and sense of well-being, which is associated with dramatical gene expression changes in hippocampus. |
2021-09-29 |
2023-08-13 |
mouse |
| Dasiel O Borroto-Escuela, Mariana Pita-Rodriguez, Ramón Fores-Pons, Miguel A Barbancho, Kjell Fuxe, Manuel Narváe. Galanin and neuropeptide Y interactions elicit antidepressant activity linked to neuronal precursor cells of the dentate gyrus in the ventral hippocampus. Journal of cellular physiology. vol 236. issue 5. 2021-09-29. PMID:33044017. |
these results may provide the basis for the development of heterobivalent agonist pharmacophores, targeting galr2/npyy1r heteromers, especially in the neuronal precursor cells of the dentate gyrus in the ventral hippocampus for the novel treatment of depression. |
2021-09-29 |
2023-08-13 |
Not clear |
| Chen-Xin Li, Ying Zheng, Hong Zhu, Cheng-Wu Li, Zhang He, Cong Wang, Jian-Hua Ding, Gang Hu, Ming L. β-arrestin 2 is essential for fluoxetine-mediated promotion of hippocampal neurogenesis in a mouse model of depression. Acta pharmacologica Sinica. vol 42. issue 5. 2021-09-27. PMID:33526871. |
β-arrestin 2 is essential for fluoxetine-mediated promotion of hippocampal neurogenesis in a mouse model of depression. |
2021-09-27 |
2023-08-13 |
mouse |
| Jian Yu, Li Ren, Su Min, Feng Lv, Jie Luo, Ping Li, Yuxi Zhan. Inhibition of CB1 receptor alleviates electroconvulsive shock-induced memory impairment by regulating hippocampal synaptic plasticity in depressive rats. Psychiatry research. vol 300. 2021-09-27. PMID:33848965. |
in this work, we first found that cannabinoid receptor type 1 (cb1r) and 2-arachidonoylglycerol (2-ag) were strongly expressed in hippocampus by electroconvulsive shock (ecs) in a rat depression model established by chronic mild stress (cms). |
2021-09-27 |
2023-08-13 |
rat |