| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Leith C R Meyer, Robyn S Hetem, Linda G Fick, Duncan Mitchell, Andrea Fulle. Effects of serotonin agonists and doxapram on respiratory depression and hypoxemia in etorphine-immobilized impala (Aepyceros melampus). Journal of wildlife diseases. vol 46. issue 2. 2010-10-22. PMID:20688644. |
serotonergic ligands have the potential to reverse opioid-induced respiratory depression. |
2010-10-22 |
2023-08-12 |
Not clear |
| Leith C R Meyer, Robyn S Hetem, Linda G Fick, Duncan Mitchell, Andrea Fulle. Effects of serotonin agonists and doxapram on respiratory depression and hypoxemia in etorphine-immobilized impala (Aepyceros melampus). Journal of wildlife diseases. vol 46. issue 2. 2010-10-22. PMID:20688644. |
we examined whether any of three serotonergic ligands could reverse this depression in etorphine-immobilized (0.07 mg/kg) impala (aepyceros melampus). |
2010-10-22 |
2023-08-12 |
Not clear |
| Hiroki Sato, Ivan Skelin, Mirko Diksi. Chronic buspirone treatment decreases 5-HT1B receptor densities and the serotonin transporter but increases the density of 5-HT2A receptors in the bulbectomized rat model of depression: an autoradiographic study. Brain research. vol 1345. 2010-10-21. PMID:20501324. |
the deregulation of the serotonergic (5-ht) system is implicated in the pathophysiology of depression. |
2010-10-21 |
2023-08-12 |
rat |
| S Kloiber, M A Kohli, T Brueckl, S Ripke, M Ising, M Uhr, A Menke, P G Unschuld, S Horstmann, D Salyakina, B Muller-Myhsok, E B Binder, F Holsboer, S Luca. Variations in tryptophan hydroxylase 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression. Molecular psychiatry. vol 15. issue 7. 2010-10-18. PMID:19125159. |
variations in tryptophan hydroxylase 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression. |
2010-10-18 |
2023-08-12 |
Not clear |
| Pavel Mohr, István Bitter, Jaromír Svestka, Erich Seifritz, Oguz Karamustafalioglu, Hannu Koponen, Norman Sartoriu. Management of depression in the presence of pain symptoms. Psychiatria Danubina. vol 22. issue 1. 2010-10-08. PMID:20305585. |
alterations in noradrenergic and serotonergic neurotransmissions in the central nervous system have been implicated in the joint pathophysiology of depression and chronic pain. |
2010-10-08 |
2023-08-12 |
Not clear |
| Gonzalo Laje, Dara M Cannon, Andrew S Allen, Jackie M Klaver, Summer A Peck, Xinmin Liu, Husseini K Manji, Wayne C Drevets, Francis J McMaho. Genetic variation in HTR2A influences serotonin transporter binding potential as measured using PET and [11C]DASB. The international journal of neuropsychopharmacology. vol 13. issue 6. 2010-09-29. PMID:20047709. |
while further work is needed to identify the actual functional genetic variants involved, these results suggest that a relationship exists between genetic variation in htr2a and either 5-htt expression or central serotonergic transmission that influences the therapeutic response to 5-htt inhibition in major depression. |
2010-09-29 |
2023-08-12 |
human |
| Claudio N Soares, Benicio N Fre. Challenges and opportunities to manage depression during the menopausal transition and beyond. The Psychiatric clinics of North America. vol 33. issue 2. 2010-09-03. PMID:20385338. |
the use of transdermal estradiol, as well as serotonergic and noradrenergic antidepressants, is an efficacious strategy in the treatment of depression and vasomotor symptoms in symptomatic women in midlife. |
2010-09-03 |
2023-08-12 |
Not clear |
| V C d'Agostino, E Francia, V Licursi, R Cerb. Clinical and personality features of allodynic migraine. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 31 Suppl 1. 2010-08-17. PMID:20464611. |
interestingly, ca appears to be associated with depression and a particular personality profile characterized by higher values of ha, suggesting an involvement of the serotonergic system in the development of ca in migraine. |
2010-08-17 |
2023-08-12 |
Not clear |
| Yelizaveta Sher, Sermsak Lolak, José R Maldonad. The impact of depression in heart disease. Current psychiatry reports. vol 12. issue 3. 2010-08-09. PMID:20425289. |
many hypothesized and studied mechanisms have linked depression and heart disease, including serotonergic pathway and platelet dysfunction, inflammation, autonomic nervous system and hypothalamic-pituitary-adrenal axis imbalance, and psychosocial factors. |
2010-08-09 |
2023-08-12 |
Not clear |
| Eduardo Pineda, Don Shin, Raman Sankar, Andrey M Mazarat. Comorbidity between epilepsy and depression: experimental evidence for the involvement of serotonergic, glucocorticoid, and neuroinflammatory mechanisms. Epilepsia. vol 51 Suppl 3. 2010-08-03. PMID:20618414. |
comorbidity between epilepsy and depression: experimental evidence for the involvement of serotonergic, glucocorticoid, and neuroinflammatory mechanisms. |
2010-08-03 |
2023-08-12 |
rat |
| Eduardo Pineda, Don Shin, Raman Sankar, Andrey M Mazarat. Comorbidity between epilepsy and depression: experimental evidence for the involvement of serotonergic, glucocorticoid, and neuroinflammatory mechanisms. Epilepsia. vol 51 Suppl 3. 2010-08-03. PMID:20618414. |
pharmacologic studies have suggested that depressive impairments following se develop as a result of enhanced interleukin-1beta signaling in the hippocampus, which leads to depression via inducing perturbations in the hpa axis and subsequent deficit in the raphe-hippocampal serotonergic transmission. |
2010-08-03 |
2023-08-12 |
rat |
| Sabine Riemer, Michael Maes, Armand Christophe, Winfried Rie. Lowered omega-3 PUFAs are related to major depression, but not to somatization syndrome. Journal of affective disorders. vol 123. issue 1-3. 2010-07-26. PMID:19720401. |
depletion of omega-3 pufas may be related to the immune and serotonergic pathophysiologies of depression by alterations in membrane fluidity and modulation of membrane receptors, enzyme activities and carriers. |
2010-07-26 |
2023-08-12 |
human |
| A J Matthews, R Brun. An investigation of factors associated with depressive symptoms among a sample of regular ecstasy consumers. Neuropsychobiology. vol 61. issue 4. 2010-07-13. PMID:20389132. |
methylenedioxymethamphetamine affects the central serotonergic system, and there is some evidence for an association between ecstasy use (drugs sold as methylenedioxymethamphetamine) and depression. |
2010-07-13 |
2023-08-12 |
Not clear |
| Iu O Fedotov. [Participation of 5-HT2A/2C AND 5-HT2A/2C subtypes of serotonergic receptors in anxiety-depressive-like behaviur of females rats in key phases of ovary cycle]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. vol 96. issue 4. 2010-07-13. PMID:20564963. |
the data obtained indicate a close interaction between ovary hormonal and serotonergic systems of the brain in mechanisms of anxiety and depression. |
2010-07-13 |
2023-08-12 |
rat |
| Eva L van Donkelaar, Paul A T Kelly, Neil Dawson, Arjan Blokland, Jos Prickaerts, Harry W M Steinbusch, Linda Ferringto. Acute tryptophan depletion potentiates 3,4-methylenedioxymethamphetamine-induced cerebrovascular hyperperfusion in adult male Wistar rats. Journal of neuroscience research. vol 88. issue 7. 2010-06-30. PMID:19998482. |
the serotonergic (5-hydroxytryptamine; 5-ht) dysfunction found in depression may affect not only brain function (mood) but also cerebrovascular control. |
2010-06-30 |
2023-08-12 |
rat |
| John G Keilp, Maria A Oquendo, Barbara H Stanley, Ainsley K Burke, Thomas B Cooper, Kevin M Malone, J John Man. Future suicide attempt and responses to serotonergic challenge. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 5. 2010-06-21. PMID:18354392. |
blunted neurohormonal responses to serotonergic agents are found in major depression and suicidal behavior, but there have been no prospective studies of their relationship to later suicide attempt. |
2010-06-21 |
2023-08-12 |
human |
| R Rajkumar, R Mahes. Assessing the neuronal serotonergic target-based antidepressant stratagem: impact of in vivo interaction studies and knockout models. Current neuropharmacology. vol 6. issue 3. 2010-06-18. PMID:19506722. |
serotonergic control of depression embraces the recent molecular requirements such as influence on proliferation, neurogenesis, plasticity, synaptic (re)modeling and transmission in the central nervous system. |
2010-06-18 |
2023-08-12 |
Not clear |
| J L Mace, R J Porter, J C Dalrymple-Alford, T J Anderso. The effects of acute tryptophan depletion on mood in patients with Parkinson's disease and the healthy elderly. Journal of psychopharmacology (Oxford, England). vol 24. issue 4. 2010-06-18. PMID:19625388. |
reduced serotonergic tone may be a compensatory adaptation to reduced dopaminergic activity in parkinson's disease (pd) and may result in vulnerability to depression. |
2010-06-18 |
2023-08-12 |
Not clear |
| J L Mace, R J Porter, J C Dalrymple-Alford, T J Anderso. The effects of acute tryptophan depletion on mood in patients with Parkinson's disease and the healthy elderly. Journal of psychopharmacology (Oxford, England). vol 24. issue 4. 2010-06-18. PMID:19625388. |
the results do not support the hypothesis that low serotonergic tone results in vulnerability to depression in pd and are in accord with an earlier study using the same technique in pd. |
2010-06-18 |
2023-08-12 |
Not clear |
| David M Marks, Chi-Un Pae, Ashwin A Patka. Triple reuptake inhibitors: the next generation of antidepressants. Current neuropharmacology. vol 6. issue 4. 2010-06-11. PMID:19587855. |
depression has been associated with impaired neurotransmission of serotonergic, norepinephrinergic, and dopaminergic pathways, although most pharmacologic treatment strategies for depression enhance only serotonin and norepinephrine neurotransmission. |
2010-06-11 |
2023-08-12 |
Not clear |