| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Galina T Shishkina, Tatyana S Kalinina, Inna V Berezova, Nikolay N Dygal. Stress-induced activation of the brainstem Bcl-xL gene expression in rats treated with fluoxetine: correlations with serotonin metabolism and depressive-like behavior. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21740920. |
mechanisms underlying stress-induced depression and antidepressant drug action were shown to involve alterations in serotonergic (5-ht) neurotransmission and expression of genes coding for proteins associated with neurotrophic signaling pathways and cell-survival in the hippocampus and cortex. |
2012-08-13 |
2023-08-12 |
rat |
| A Raftogianni, A Diamantopoulou, F Alikaridis, A Stamatakis, F Stylianopoulo. Effects of interaction of an early experience of reward through maternal contact or its denial with social stress during adolescence on the serotonergic system and the stress responsiveness of adult female rats. Neuroscience. vol 209. 2012-07-30. PMID:22381469. |
the serotonergic system is known as an important modulator of coping ability and, in general, emotional balance in both normal and pathological states, such as depression and anxiety, for which females are more vulnerable. |
2012-07-30 |
2023-08-12 |
rat |
| Ulla Knorr, Maj Vinberg, Erik Lykke Mortensen, Per Winkel, Christian Gluud, Jørn Wetterslev, Ulrik Gether, Lars Vedel Kessin. Effect of chronic escitalopram versus placebo on personality traits in healthy first-degree relatives of patients with depression: a randomized trial. PloS one. vol 7. issue 2. 2012-07-23. PMID:22393376. |
the serotonergic neurotransmitter system is closely linked to depression and personality traits. |
2012-07-23 |
2023-08-12 |
Not clear |
| Masahide Fukada, Atsuko Hanai, Atsuo Nakayama, Takayoshi Suzuki, Naoki Miyata, Ramona M Rodriguiz, William C Wetsel, Tso-Pang Yao, Yoshiharu Kawaguch. Loss of deacetylation activity of Hdac6 affects emotional behavior in mice. PloS one. vol 7. issue 2. 2012-06-11. PMID:22328923. |
these findings suggest that hdac6-mediated reversible acetylation might contribute to maintain proper neuronal activity in serotonergic neurons, and also provide a new therapeutic target for depression. |
2012-06-11 |
2023-08-12 |
mouse |
| Benedicte Ballanger, Helene Klinger, Julien Eche, Jérôme Lerond, Anne-Evelyne Vallet, Didier Le Bars, Leon Tremblay, Véronique Sgambato-Faure, Emmanuel Broussolle, Stéphane Thoboi. Role of serotonergic 1A receptor dysfunction in depression associated with Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 27. issue 1. 2012-05-21. PMID:21994070. |
role of serotonergic 1a receptor dysfunction in depression associated with parkinson's disease. |
2012-05-21 |
2023-08-12 |
human |
| Benedicte Ballanger, Helene Klinger, Julien Eche, Jérôme Lerond, Anne-Evelyne Vallet, Didier Le Bars, Leon Tremblay, Véronique Sgambato-Faure, Emmanuel Broussolle, Stéphane Thoboi. Role of serotonergic 1A receptor dysfunction in depression associated with Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society. vol 27. issue 1. 2012-05-21. PMID:21994070. |
the objective of the present study was to use positron emission tomography and [(18)f]mppf to investigate the role of postsynaptic serotonergic system dysfunction in the pathophysiology of depression in parkinson's disease. |
2012-05-21 |
2023-08-12 |
human |
| Catherine A Hartley, Morgan C McKenna, Rabia Salman, Andrew Holmes, B J Casey, Elizabeth A Phelps, Charles E Glat. Serotonin transporter polyadenylation polymorphism modulates the retention of fear extinction memory. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 14. 2012-05-21. PMID:22431634. |
the propensity to form persistent fear associations due to poor extinction recall may be an intermediate phenotype mediating the effects of genetic variation in serotonergic function on anxiety and depression. |
2012-05-21 |
2023-08-12 |
mouse |
| Carla S Lima, André L Nunes-Freitas, Anderson Ribeiro-Carvalho, Cláudio C Filgueiras, Alex C Manhães, Armando Meyer, Yael Abreu-Villaç. Exposure to methamidophos at adulthood adversely affects serotonergic biomarkers in the mouse brain. Neurotoxicology. vol 32. issue 6. 2012-05-02. PMID:21871486. |
considering the association between depression and the serotonergic (5ht) system, in the present study we investigated whether a subchronic exposure to methamidophos affects the serotonergic system of adult mice. |
2012-05-02 |
2023-08-12 |
mouse |
| Jae-Min Kim, Sung-Wan Kim, Robert Stewart, Seon-Young Kim, Il-Seon Shin, Min-Ho Park, Jung-Han Yoon, Ji-Shin Lee, Sung-Woo Park, Young-Hoon Kim, Jin-Sang Yoo. Serotonergic and BDNF genes associated with depression 1 week and 1 year after mastectomy for breast cancer. Psychosomatic medicine. vol 74. issue 1. 2012-04-24. PMID:22210241. |
serotonergic and bdnf genes associated with depression 1 week and 1 year after mastectomy for breast cancer. |
2012-04-24 |
2023-08-12 |
Not clear |
| Thibault Renoir, Terence Y Pang, Laurence Lanfume. Drug withdrawal-induced depression: serotonergic and plasticity changes in animal models. Neuroscience and biobehavioral reviews. vol 36. issue 1. 2012-04-19. PMID:22037449. |
drug withdrawal-induced depression: serotonergic and plasticity changes in animal models. |
2012-04-19 |
2023-08-12 |
human |
| Thibault Renoir, Terence Y Pang, Laurence Lanfume. Drug withdrawal-induced depression: serotonergic and plasticity changes in animal models. Neuroscience and biobehavioral reviews. vol 36. issue 1. 2012-04-19. PMID:22037449. |
following, we provide a more in-depth discussion of the role of serotonergic neurotransmission and hypothalamic-pituitary-adrenal (hpa) axis regulation as well as the neurogenic changes occurring after chronic drug intake focusing on the withdrawal associated depression. |
2012-04-19 |
2023-08-12 |
human |
| Dag Aarsland, Sven Påhlhagen, Clive G Ballard, Uwe Ehrt, Per Svenningsso. Depression in Parkinson disease--epidemiology, mechanisms and management. Nature reviews. Neurology. vol 8. issue 1. 2012-04-19. PMID:22198405. |
changes in dopaminergic, noradrenergic and serotonergic systems in patients with pd might help to explain the incidence of depression in these individuals. |
2012-04-19 |
2023-08-12 |
Not clear |
| Dag Aarsland, Sven Påhlhagen, Clive G Ballard, Uwe Ehrt, Per Svenningsso. Depression in Parkinson disease--epidemiology, mechanisms and management. Nature reviews. Neurology. vol 8. issue 1. 2012-04-19. PMID:22198405. |
antidepressants that have dual serotonergic and noradrenergic effects are the drugs of choice for treating depression in pd. |
2012-04-19 |
2023-08-12 |
Not clear |
| Clement Hamani, Danilo C Machado, Débora C Hipólide, Francisco P Dubiela, Deborah Suchecki, Carlos E Macedo, Fabio Tescarollo, Uilton Martins, Luciene Covolan, José N Nobreg. Deep brain stimulation reverses anhedonic-like behavior in a chronic model of depression: role of serotonin and brain derived neurotrophic factor. Biological psychiatry. vol 71. issue 1. 2012-03-30. PMID:22000731. |
we have studied the effects of ventromedial prefrontal cortex (vmpfc) stimulation in a chronic model of depression and assessed the involvement of the serotonergic system and brain derived neurotrophic factor (bdnf) in a dbs response. |
2012-03-30 |
2023-08-12 |
Not clear |
| Saima Khaliq, Saida Haider, Faizan Naqvi, Tahira Perveen, Sadia Saleem, Darakhshan Jabeen Halee. Altered brain serotonergic neurotransmission following caffeine withdrawal produces behavioral deficits in rats. Pakistan journal of pharmaceutical sciences. vol 25. issue 1. 2012-03-08. PMID:22186305. |
the results of this study are linked with caffeine induced alterations in serotonergic neurotransmission and its role in memory and depression. |
2012-03-08 |
2023-08-12 |
rat |
| Masaki Ogaya, Juhyon Kim, Kazuo Sasak. Ghrelin postsynaptically depolarizes dorsal raphe neurons in rats in vitro. Peptides. vol 32. issue 8. 2012-02-24. PMID:21763741. |
serotonergic system is considered to be implicated in feeding, depression and other mood disorders, and sleep. |
2012-02-24 |
2023-08-12 |
rat |
| Mitsuhiro Kamata, Akihito Suzuki, Keizo Yoshida, Hitoshi Takahashi, Hisashi Higuchi, Koichi Otan. Genetic polymorphisms in the serotonergic system and symptom clusters of major depressive disorder. Journal of affective disorders. vol 135. issue 1-3. 2012-01-25. PMID:21917318. |
the purpose of this study was to examine the associations of genetic polymorphisms in the serotonergic system with three factors of the montgomery-Åsberg depression rating scale (madrs), i.e., dysphoria, retardation, and vegetative symptoms. |
2012-01-25 |
2023-08-12 |
Not clear |
| Franziska Geiser, Rupert Conrad, Katrin Imbierowicz, Christian Meier, Reinhard Liedtke, Dietrich Klingmüller, Johannes Oldenburg, Ursula Harbrech. Coagulation activation and fibrinolysis impairment are reduced in patients with anxiety and depression when medicated with serotonergic antidepressants. Psychiatry and clinical neurosciences. vol 65. issue 5. 2012-01-05. PMID:21851461. |
coagulation activation and fibrinolysis impairment are reduced in patients with anxiety and depression when medicated with serotonergic antidepressants. |
2012-01-05 |
2023-08-12 |
Not clear |
| Walter André dos Santos Moraes, Patrick Rademaker Burke, Pablo Lorenzon Coutinho, Christian Guilleminault, Aline Gomes Bittencourt, Sergio Tufik, Dalva Poyare. Sedative antidepressants and insomnia. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999). vol 33. issue 1. 2011-12-12. PMID:21537726. |
the present review addresses the relationship between sleep and depression and how serotonergic transmission is implicated in both conditions. |
2011-12-12 |
2023-08-12 |
Not clear |
| Giovanni Tarantino, S Savastano, A Colao, G Polichetti, D Capon. Urinary excretion of 5-hydroxy-3-indoleacetic acid in dystimic/depressed, adult obese women: what correlations to hepatic steatosis? International journal of immunopathology and pharmacology. vol 24. issue 3. 2011-12-02. PMID:21978708. |
previous data support the view that depression involves serotonergic systems, reflecting low levels of urinary 5- hydroxy-3-indoleacetic acid (5-hiaa). |
2011-12-02 |
2023-08-12 |
Not clear |