| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Gabriel Manjarrez-Gutiérrez, Rodolfo Ramírez-Campillo, Gabriela Borrayo-Sánchez, Jorge Hernández-Rodrígue. Disturbance of serotonergic neurotransmission in patients with postmyocardial infarction and depression. Metabolic brain disease. vol 28. issue 1. 2013-08-02. PMID:23129293. |
these findings suggest an important deterioration of brain serotonergic activity as a pathophysiological mechanism in post-mi patients for the development of clinical depression. |
2013-08-02 |
2023-08-12 |
Not clear |
| Pilar A Saiz, Sara Martínez-Barrondo, María P García-Portilla, Paul Corcoran, Blanca Morales, María-Teresa Bascaran, Begoña Paredes, Victoria Alvarez, Eliecer Coto, Juan M Fernández, Manuel Bousoño, Julio Bobe. Role of serotonergic polymorphisms in the clinical severity of the panic disorder. Revista de psiquiatria y salud mental. vol 2. issue 1. 2013-07-25. PMID:23034196. |
to investigate the association between three serotonergic polymorphisms (a-1438g [rs6311] of the htr2a gene, stin2 vntr and 5-httlpr of the slc6a4 gene) and the severity of panic and depression symptomatology among mental health outpatients with diagnosis of panic disorder (pd). |
2013-07-25 |
2023-08-12 |
Not clear |
| Tanja Hochstrasser, Lindsay A Hohsfield, Barbara Sperner-Unterweger, Christian Humpe. β-Amyloid induced effects on cholinergic, serotonergic, and dopaminergic neurons is differentially counteracted by anti-inflammatory drugs. Journal of neuroscience research. vol 91. issue 1. 2013-07-18. PMID:22996751. |
the aim of the present study was to investigate the effects of aβ(1-42) on cholinergic neurons of the nucleus basalis of meynert (which degenerate in ad), on serotonergic neurons of the dorsal raphe nucleus (which play a role in depression), and on dopaminergic neurons of the ventral mesencephalon (which degenerate in pd) in rat organotypic brain slices. |
2013-07-18 |
2023-08-12 |
rat |
| P Baldinger, G Kranz, A Höflich, M Savli, P Stein, R Lanzenberger, S Kaspe. [The effects of hormone replacement therapy on mind and brain]. Der Nervenarzt. vol 84. issue 1. 2013-06-26. PMID:22318360. |
the important role of the neurotransmitter serotonin in the pathogenesis of anxiety disorders and major depression is unquestioned, but only little is known about the influence of sex hormones on the serotonergic system. |
2013-06-26 |
2023-08-12 |
Not clear |
| Matthew W Hale, Charles L Raison, Christopher A Lowr. Integrative physiology of depression and antidepressant drug action: implications for serotonergic mechanisms of action and novel therapeutic strategies for treatment of depression. Pharmacology & therapeutics. vol 137. issue 1. 2013-06-20. PMID:23017938. |
integrative physiology of depression and antidepressant drug action: implications for serotonergic mechanisms of action and novel therapeutic strategies for treatment of depression. |
2013-06-20 |
2023-08-12 |
Not clear |
| Jennifer Gladys Mulle, Viola Vaccarin. Cardiovascular disease, psychosocial factors, and genetics: the case of depression. Progress in cardiovascular diseases. vol 55. issue 6. 2013-06-20. PMID:23621965. |
while the underlying biology behind this relationship is unclear, recent data support contributions from inflammatory or serotonergic pathways toward the comorbidity between cvd and depression. |
2013-06-20 |
2023-08-12 |
Not clear |
| Kun Zhang, Haiyun Xu, Longlong Cao, Kangsheng Li, Qingjun Huan. Interleukin-1β inhibits the differentiation of hippocampal neural precursor cells into serotonergic neurons. Brain research. vol 1490. 2013-05-29. PMID:23085314. |
the aim of this study was to examine the effect of il-1β on the differentiation of hippocampal npcs into functional serotonergic neurons, which play important roles in the pathophysiology and treatment of depression. |
2013-05-29 |
2023-08-12 |
rat |
| Alkistis Skalkidou, Charlotte Hellgren, Erika Comasco, Sara Sylvén, Inger Sundström Poroma. Biological aspects of postpartum depression. Women's health (London, England). vol 8. issue 6. 2013-05-23. PMID:23181531. |
in light of the normal physiology, the authors also attempt to describe the current evidence of the biological changes associated with the development of depression in the postpartum period, including ovarian steroids, the hypothalamic-pituitary-adrenal axis, the serotonergic neurotransmitter system, the thyroid system and inflammatory markers. |
2013-05-23 |
2023-08-12 |
Not clear |
| Jung-Ah Min, Seung-Hwan Lee, Seung-Yup Lee, Jeong-Ho Chae, Chang-Uk Lee, Young-Min Park, Sung-Man Ba. Clinical characteristics associated with different strengths of loudness dependence of auditory evoked potentials (LDAEP) in major depressive disorder. Psychiatry research. vol 200. issue 2-3. 2013-05-17. PMID:23021319. |
loudness dependence of auditory evoked potentials (ldaep), also called as intensity dependence of auditory evoked potentials (idap), has been proposed as a potential marker for central serotonergic tone and has been noticed for its possible clinical implications in depression. |
2013-05-17 |
2023-08-12 |
Not clear |
| Ivan Skelin, Tomislav Kovačević, Hiroki Sato, Mirko Diksi. The opposite effect of a 5-HT1B receptor agonist on 5-HT synthesis, as well as its resistant counterpart, in an animal model of depression. Brain research bulletin. vol 88. issue 5. 2013-04-25. PMID:22542420. |
flinders sensitive line (fsl) rat is as an animal model of depression with altered parameters of the serotonergic (5-ht) system function (5-ht synthesis rates, tissue concentrations, release, receptor density and affinity), as well as an altered sensitivity of these parameters to different 5-ht based antidepressants. |
2013-04-25 |
2023-08-12 |
rat |
| N M Maksimova, O P Vertogradov. [The dynamics of anxious depression under the treatment with antidepressants with different mechanisms of action]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 112. issue 11 Pt 2. 2013-04-17. PMID:23257755. |
peculiarities of the dynamics of anxious depression under the treatment with selective serotonergic antidepressants with different mechanisms of action on the serotonin reuptake were investigated. |
2013-04-17 |
2023-08-12 |
Not clear |
| Iu O Fedotova, N E Ordian, H O Frolova, V I Sobolie. [Involvement of some subtypes of 5-HT2-receptors in affective behavior in female rats]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). vol 58. issue 6. 2013-04-08. PMID:23530416. |
the data obtained indicate a close interaction between the ovary hormonal and serotonergic systems of the brain in the mechanisms of anxiety and depression. |
2013-04-08 |
2023-08-12 |
rat |
| Karim Malki, Anbarasu Lourdusamy, Elke Binder, Jose Payá-Cano, Frans Sluyter, Ian Craig, Robert Keers, Peter McGuffin, Rudolf Uher, Leonard C Schalkwy. Antidepressant-dependent mRNA changes in mouse associated with hippocampal neurogenesis in a mouse model of depression. Pharmacogenetics and genomics. vol 22. issue 11. 2013-04-04. PMID:23026812. |
here, we report a mouse mrna expression study to evaluate the effect of escitalopram (a serotonergic antidepressant) and nortriptyline (a noradrenergic antidepressant) on genes that are involved in the pathogenesis of depression and to assess the similarities and differences between two drugs on gene expression levels. |
2013-04-04 |
2023-08-12 |
mouse |
| Jonathan P Roiser, Jamey Levy, Stephen J Fromm, David Goldman, Colin A Hodgkinson, Gregor Hasler, Barbara J Sahakian, Wayne C Drevet. Serotonin transporter genotype differentially modulates neural responses to emotional words following tryptophan depletion in patients recovered from depression and healthy volunteers. Journal of psychopharmacology (Oxford, England). vol 26. issue 11. 2013-03-18. PMID:22495688. |
previous studies have suggested that polymorphism in the serotonin transporter gene (5-httlpr) influences responses to serotonergic manipulation, with opposite effects in patients recovered from depression (rmdd) and controls. |
2013-03-18 |
2023-08-12 |
human |
| Donald F Smith, Steen Jakobse. Molecular Neurobiology of Depression: PET Findings on the Elusive Correlation with Symptom Severity. Frontiers in psychiatry. vol 4. 2013-03-06. PMID:23459670. |
recent pet studies of human depression have focused on serotonergic, dopaminergic, muscarinic, nicotinic, and gabaergic receptors, as well as central processes dependent on monoamine oxidase, phosphodiesterase type 4, amyloid plaques, neurofibrillar tangles, and p-glycoprotein. |
2013-03-06 |
2023-08-12 |
human |
| S Alisha Epps, David Weinshenke. Rhythm and blues: animal models of epilepsy and depression comorbidity. Biochemical pharmacology. vol 85. issue 2. 2013-02-25. PMID:22940575. |
studies on these animal models point to some potential mechanisms that could explain epilepsy and depression comorbidity, such as various components of the dopaminergic, noradrenergic, serotonergic, and gabaergic systems, as well as key brain regions, like the amygdala and hippocampus. |
2013-02-25 |
2023-08-12 |
rat |
| Jia Zhang, Yan Fan, Ying Li, Hobart Zhu, Liang Wang, Meng-Yang Zh. Chronic social defeat up-regulates expression of the serotonin transporter in rat dorsal raphe nucleus and projection regions in a glucocorticoid-dependent manner. Journal of neurochemistry. vol 123. issue 6. 2013-02-14. PMID:23061525. |
chronic stress and dysfunction of the serotonergic system in the brain have been considered two of the major risks for development of depression. |
2013-02-14 |
2023-08-12 |
rat |
| Jia Zhang, Yan Fan, Ying Li, Hobart Zhu, Liang Wang, Meng-Yang Zh. Chronic social defeat up-regulates expression of the serotonin transporter in rat dorsal raphe nucleus and projection regions in a glucocorticoid-dependent manner. Journal of neurochemistry. vol 123. issue 6. 2013-02-14. PMID:23061525. |
the present findings demonstrate that chronic stress is closely correlated with the serotonergic system by acting on the regulation of the sert expression in the drn and its projection regions, which may contribute to the development of depression. |
2013-02-14 |
2023-08-12 |
rat |
| b' Branka Vidrih, Dalibor Karlovi\\xc4\\x87, Marija Bosnjak Pasi\\xc4\\x87, Melita Uremovi\\xc4\\x87, Ana Kovak Mufi\\xc4\\x87, Ana Matosi\\xc4\\x8. A review of the psychoneuroimmunologic concepts on the etiology of depressive disorders. Acta clinica Croatica. vol 51. issue 3. 2013-02-14. PMID:23330406.' |
depression is characterized by disorders in noradrenergic and serotonergic neurotransmission. |
2013-02-14 |
2023-08-12 |
Not clear |
| b' Branka Vidrih, Dalibor Karlovi\\xc4\\x87, Marija Bosnjak Pasi\\xc4\\x87, Melita Uremovi\\xc4\\x87, Ana Kovak Mufi\\xc4\\x87, Ana Matosi\\xc4\\x8. A review of the psychoneuroimmunologic concepts on the etiology of depressive disorders. Acta clinica Croatica. vol 51. issue 3. 2013-02-14. PMID:23330406.' |
proinflammatory cytokines are included in the noradrenergic and serotonergic neurotransmission in the brain areas that are thought to be involved in the pathogenesis of depression. |
2013-02-14 |
2023-08-12 |
Not clear |