| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Dima A Hammoud, Christopher J Endres, Edward Hammond, Ovsev Uzuner, Amanda Brown, Avindra Nath, Adam I Kaplin, Martin G Pompe. Imaging serotonergic transmission with [11C]DASB-PET in depressed and non-depressed patients infected with HIV. NeuroImage. vol 49. issue 3. 2010-04-13. PMID:19853044. |
the goal of this study was to evaluate the involvement of serotonergic transmission in hiv-associated depression using [(11)c]dasb, a serotonin transporter (5-htt)-specific radiopharmaceutical for positron emission tomography (pet). |
2010-04-13 |
2023-08-12 |
Not clear |
| Jesse R Fann, Tessa Hart, Katherine G Schome. Treatment for depression after traumatic brain injury: a systematic review. Journal of neurotrauma. vol 26. issue 12. 2010-03-23. PMID:19698070. |
serotonergic antidepressants and cognitive behavioral interventions appear to have the best preliminary evidence for treating depression following tbi. |
2010-03-23 |
2023-08-12 |
human |
| Gabriel Manjarrez-Gutierrez, Rocio Herrera Marquez, Susana A Mejenes-Alvarez, Teresa Godinez-Lopez, Jorge Hernandez-. Functional change of the auditory cortex related to brain serotonergic neurotransmission in type 1 diabetic adolescents with and without depression. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 10. issue 4 Pt 3. 2010-03-19. PMID:19277928. |
functional change of the auditory cortex related to brain serotonergic neurotransmission in type 1 diabetic adolescents with and without depression. |
2010-03-19 |
2023-08-12 |
human |
| Gabriel Manjarrez-Gutierrez, Rocio Herrera Marquez, Susana A Mejenes-Alvarez, Teresa Godinez-Lopez, Jorge Hernandez-. Functional change of the auditory cortex related to brain serotonergic neurotransmission in type 1 diabetic adolescents with and without depression. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 10. issue 4 Pt 3. 2010-03-19. PMID:19277928. |
the aim of this study was to determine whether diabetic patients who were depressed present a decrease of brain serotonergic activity compared to diabetic patients without depression or patients with depression but without diabetes. |
2010-03-19 |
2023-08-12 |
human |
| Gabriel Manjarrez-Gutierrez, Rocio Herrera Marquez, Susana A Mejenes-Alvarez, Teresa Godinez-Lopez, Jorge Hernandez-. Functional change of the auditory cortex related to brain serotonergic neurotransmission in type 1 diabetic adolescents with and without depression. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 10. issue 4 Pt 3. 2010-03-19. PMID:19277928. |
these findings suggest an enhanced deterioration of brain serotonergic neurotransmission in diabetic subjects with depression with abnormal responses of the auditory cortex. |
2010-03-19 |
2023-08-12 |
human |
| Hana Kovaru, Marek Pav, Frantisek Kovaru, Jiri Raboch, Anna Fiserov. Cell signalling in CNS and immune system in depression and during antidepressant treatment: focus on glial and natural killer cells. Neuro endocrinology letters. vol 30. issue 4. 2010-03-08. PMID:20010506. |
depression is associated with abnormalities in the noradrenergic, serotonergic and dopaminergic neurotransmitter systems and reductions in the level of their precursors and metabolic turnover. |
2010-03-08 |
2023-08-12 |
human |
| M Victoria Puig, Akiya Watakabe, Mika Ushimaru, Tetsuo Yamamori, Yasuo Kawaguch. Serotonin modulates fast-spiking interneuron and synchronous activity in the rat prefrontal cortex through 5-HT1A and 5-HT2A receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 6. 2010-03-05. PMID:20147548. |
alterations of the serotonergic system in the prefrontal cortex (pfc) are implicated in psychiatric disorders such as schizophrenia and depression. |
2010-03-05 |
2023-08-12 |
rat |
| M Victoria Puig, Akiya Watakabe, Mika Ushimaru, Tetsuo Yamamori, Yasuo Kawaguch. Serotonin modulates fast-spiking interneuron and synchronous activity in the rat prefrontal cortex through 5-HT1A and 5-HT2A receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 6. 2010-03-05. PMID:20147548. |
these results may provide insight into impaired serotonergic control of network activity in psychiatric illnesses such as schizophrenia and depression. |
2010-03-05 |
2023-08-12 |
rat |
| Arif Kha. Vilazodone, a novel dual-acting serotonergic antidepressant for managing major depression. Expert opinion on investigational drugs. vol 18. issue 11. 2010-02-25. PMID:19764890. |
vilazodone, a novel dual-acting serotonergic antidepressant for managing major depression. |
2010-02-25 |
2023-08-12 |
Not clear |
| Judit Lazary, Aron Lazary, Xenia Gonda, Anita Benko, Eszter Molnar, Laszlo Hunyady, Gabriella Juhasz, Gyorgy Bagd. Promoter variants of the cannabinoid receptor 1 gene (CNR1) in interaction with 5-HTTLPR affect the anxious phenotype. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 150B. issue 8. 2010-02-23. PMID:19725030. |
in conclusion, genetically determined serotonergic and endocannabinoid dysfunctions could lead to a vulnerability causing anxiety disorders and possibly depression. |
2010-02-23 |
2023-08-12 |
Not clear |
| K L Gardner, M W Hale, S Oldfield, S L Lightman, P M Plotsky, C A Lowr. Adverse experience during early life and adulthood interact to elevate tph2 mRNA expression in serotonergic neurons within the dorsal raphe nucleus. Neuroscience. vol 163. issue 4. 2010-02-12. PMID:19647049. |
anxiety disorders, depression and animal models of vulnerability to a depression-like syndrome have been associated with dysregulation of brain serotonergic systems. |
2010-02-12 |
2023-08-12 |
rat |
| J Vignau, O Costisella, V Canva, M Imbenotte, A Duhamel, M Lhermitt. [Impact of interferon alpha immunotherapy on tryptophan metabolism in patients with chronic hepatitis C. Results of a pilot studies on ten patients]. L'Encephale. vol 35. issue 5. 2010-02-01. PMID:19853722. |
various mechanisms have been incriminated to explain the production of depression and anxiety symptoms, among which serotonergic hypothesis is supported by a growing body of evidence. |
2010-02-01 |
2023-08-12 |
Not clear |
| S J Bull, P Huezo-Diaz, E B Binder, J F Cubells, G Ranjith, C Maddock, C Miyazaki, N Alexander, M Hotopf, A J Cleare, S Norris, E Cassidy, K J Aitchison, A H Miller, C M Pariant. Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon-alpha and ribavirin treatment. Molecular psychiatry. vol 14. issue 12. 2010-01-27. PMID:18458677. |
depression and fatigue are frequent side effects of interferon-alpha (ifn-alpha) treatment, and there is compelling evidence that the inflammatory response system (including interleukin-6, il-6) and the serotonergic system is important in the pathophysiology of such symptoms. |
2010-01-27 |
2023-08-12 |
Not clear |
| Adolfo Sequeira, Firoza Mamdani, Carl Ernst, Marquis P Vawter, William E Bunney, Veronique Lebel, Sonia Rehal, Tim Klempan, Alain Gratton, Chawki Benkelfat, Guy A Rouleau, Naguib Mechawar, Gustavo Tureck. Global brain gene expression analysis links glutamatergic and GABAergic alterations to suicide and major depression. PloS one. vol 4. issue 8. 2010-01-19. PMID:19668376. |
most studies investigating the neurobiology of depression and suicide have focused on the serotonergic system. |
2010-01-19 |
2023-08-12 |
Not clear |
| Katherine L Gardner, Matthew W Hale, Stafford L Lightman, Paul M Plotsky, Christopher A Lowr. Adverse early life experience and social stress during adulthood interact to increase serotonin transporter mRNA expression. Brain research. vol 1305. 2010-01-05. PMID:19781533. |
anxiety disorders, depression and animal models of vulnerability to a depression-like syndrome have been associated with dysregulation of serotonergic systems in the brain. |
2010-01-05 |
2023-08-12 |
rat |
| Li-Tao Yi, Li Zhang, An-Wei Ding, Qun Xu, Qin Zhu, Ling-Dong Kon. Orthogonal array design for antidepressant compatibility of polysaccharides from Banxia-Houpu decoction, a traditional Chinese herb prescription in the mouse models of depression. Archives of pharmacal research. vol 32. issue 10. 2010-01-04. PMID:19898805. |
therefore, pmb x pfp and ppo x pfp interactions on antidepressant-like effects were the cores in compatibility of polysaccharides from banxia-houpu decoction by attenuating abnormalities in the serotonergic and dopaminergic system functions in animal models of depression. |
2010-01-04 |
2023-08-12 |
mouse |
| Britta Haenisch, Karoline Linsel, Michael Brüss, Ralf Gilsbach, Peter Propping, Markus M Nöthen, Marcella Rietschel, Rolf Fimmers, Wolfgang Maier, Astrid Zobel, Susanne Höfels, Vera Guttenthaler, Manfred Göthert, Heinz Bönisc. Association of major depression with rare functional variants in norepinephrine transporter and serotonin1A receptor genes. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 150B. issue 7. 2009-12-28. PMID:19105200. |
dysregulations of central noradrenergic and serotonergic neurotransmission have been suggested to contribute to the pathogenesis of neuropsychiatric disorders such as depression. |
2009-12-28 |
2023-08-12 |
human |
| Esther Berrocoso, Juan-Antonio Mic. Cooperative opioid and serotonergic mechanisms generate superior antidepressant-like effects in a mice model of depression. The international journal of neuropsychopharmacology. vol 12. issue 8. 2009-12-04. PMID:19341511. |
cooperative opioid and serotonergic mechanisms generate superior antidepressant-like effects in a mice model of depression. |
2009-12-04 |
2023-08-12 |
mouse |
| Esther Berrocoso, Juan-Antonio Mic. Cooperative opioid and serotonergic mechanisms generate superior antidepressant-like effects in a mice model of depression. The international journal of neuropsychopharmacology. vol 12. issue 8. 2009-12-04. PMID:19341511. |
these data support the hypothesis that a combination of classical serotonergic antidepressants and weak opioid receptor agonists may be a helpful new strategy in the treatment of refractory depression. |
2009-12-04 |
2023-08-12 |
mouse |
| Susanne Nikolaus, Christina Antke, Hans-Wilhelm Mülle. In vivo imaging of synaptic function in the central nervous system: II. Mental and affective disorders. Behavioural brain research. vol 204. issue 1. 2009-12-01. PMID:19523495. |
results on both dopaminergic and serotonergic neurotransmission are inconsistent in both major depressive disorder and bipolar illness, and fail to clearly agree with the dopamine and/or serotonin hypothesis of depression. |
2009-12-01 |
2023-08-12 |
human |