| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Reiji Yoshimura, Masae Mitoma, Atsuko Sugita, Hikaru Hori, Tatsuya Okamoto, Wakako Umene, Nobuhisa Ueda, Jun Nakamur. Effects of paroxetine or milnacipran on serum brain-derived neurotrophic factor in depressed patients. Progress in neuro-psychopharmacology & biological psychiatry. vol 31. issue 5. 2007-08-28. PMID:17459550. |
researchers have reported that serum bdnf levels in drug-free depressed patients are lower than those of healthy controls, and have proposed that these low levels might reflect a failure of neuronal plasticity in depression. |
2007-08-28 |
2023-08-12 |
Not clear |
| Justine M Gatt, C Richard Clark, Andrew H Kemp, Belinda J Liddell, Carol Dobson-Stone, Stacey A Kuan, Peter R Schofield, Leanne M William. A genotype-endophenotype-phenotype path model of depressed mood: integrating cognitive and emotional markers. Journal of integrative neuroscience. vol 6. issue 1. 2007-07-24. PMID:17472225. |
the brain-derived neurotrophic factor (bdnf) 66met allele may contribute to both cognitive and emotional aspects of the depression phenotype. |
2007-07-24 |
2023-08-12 |
Not clear |
| Chi-Un Pae, Chul Lee, In-Ho Pai. Therapeutic implication of cocaine- and amphetamine-regulated transcript (CART) in the treatment of depression. Medical hypotheses. vol 69. issue 1. 2007-07-18. PMID:17196760. |
the regulation of the signal transduction pathways by cart by modulating neurotrophic factors, such as brain-derived neurotrophic factor (bdnf), kinases (trkb), and neurotransmitters (5-ht), can also contribute to the treatment of depression. |
2007-07-18 |
2023-08-12 |
Not clear |
| Christoph Laske, Elke Stransky, Gerhard W Eschweiler, Reinhild Klein, Andreas Wittorf, Thomas Leyhe, Elke Richartz, Niklas Köhler, Matthias Bartels, Gerhard Buchkremer, Klaus Schot. Increased BDNF serum concentration in fibromyalgia with or without depression or antidepressants. Journal of psychiatric research. vol 41. issue 7. 2007-07-16. PMID:16600301. |
increased bdnf serum concentration in fibromyalgia with or without depression or antidepressants. |
2007-07-16 |
2023-08-12 |
Not clear |
| Christoph Laske, Elke Stransky, Gerhard W Eschweiler, Reinhild Klein, Andreas Wittorf, Thomas Leyhe, Elke Richartz, Niklas Köhler, Matthias Bartels, Gerhard Buchkremer, Klaus Schot. Increased BDNF serum concentration in fibromyalgia with or without depression or antidepressants. Journal of psychiatric research. vol 41. issue 7. 2007-07-16. PMID:16600301. |
in addition, bdnf serum concentrations in fm patients were independent from age, gender, illness duration, preexisting recurrent major depression and antidepressive medication in low doses. |
2007-07-16 |
2023-08-12 |
Not clear |
| V E Golimbet, L I Abramova, V G Kaleda, M V Alfimova, G I Korovaĭtseva, O M Lavrushina, A N Barkhatov. [The molecular-genetic aspects of differentiation of schizoaffective psychosis and attack-like progressive schizophrenia]. Vestnik Rossiiskoi akademii meditsinskikh nauk. issue 3. 2007-07-09. PMID:17500207. |
molecular-genetic studies revealed higher frequencies of s allele and ss genotype (5-httlpr polymorphism), which are thought to be associated with depression and depressive symptoms, and higher frequency of bdnf genotypes, containing met allele, in combination with 5-httlrp genotypes containing l allele, in patients with sap as compared to the schizophrenic group. |
2007-07-09 |
2023-08-12 |
human |
| Shih-Jen Tsa. Statins may enhance the proteolytic cleavage of proBDNF: implications for the treatment of depression. Medical hypotheses. vol 68. issue 6. 2007-07-03. PMID:17097821. |
evidence suggests that increasing central bdnf activity plays an important role in the treatment of major depression. |
2007-07-03 |
2023-08-12 |
Not clear |
| Bingjin Li, Katsuya Suemaru, Yoshihisa Kitamura, Ranji Cui, Yutaka Gomita, Hiroaki Arak. [Strategy to develop a new drug for treatment-resistant depression--role of electroconvulsive stimuli and BDNF]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 127. issue 4. 2007-06-12. PMID:17409705. |
[strategy to develop a new drug for treatment-resistant depression--role of electroconvulsive stimuli and bdnf]. |
2007-06-12 |
2023-08-12 |
rat |
| Bingjin Li, Katsuya Suemaru, Yoshihisa Kitamura, Ranji Cui, Yutaka Gomita, Hiroaki Arak. [Strategy to develop a new drug for treatment-resistant depression--role of electroconvulsive stimuli and BDNF]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 127. issue 4. 2007-06-12. PMID:17409705. |
brain-derived neurotrophic factor (bdnf) is a neurotrophic factor that plays an important role in the morphological changes associated with depression and the mechanisms of antidepressants. |
2007-06-12 |
2023-08-12 |
rat |
| Bingjin Li, Katsuya Suemaru, Yoshihisa Kitamura, Ranji Cui, Yutaka Gomita, Hiroaki Arak. [Strategy to develop a new drug for treatment-resistant depression--role of electroconvulsive stimuli and BDNF]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 127. issue 4. 2007-06-12. PMID:17409705. |
furthermore, the ecs treatment also markedly increased the hippocampal bdnf levels in the rat tricyclic antidepressant-resistant depression model. |
2007-06-12 |
2023-08-12 |
rat |
| Thomas Frodl, Cornelius Schüle, Gisela Schmitt, Christine Born, Thomas Baghai, Peter Zill, Ronald Bottlender, Rainer Rupprecht, Brigitta Bondy, Maximilian Reiser, Hans-Jürgen Möller, Eva M Meisenzah. Association of the brain-derived neurotrophic factor Val66Met polymorphism with reduced hippocampal volumes in major depression. Archives of general psychiatry. vol 64. issue 4. 2007-06-01. PMID:17404118. |
brain-derived neurotrophic factor (bdnf) modulates hippocampal plasticity, which is believed to be altered in patients with major depression. |
2007-06-01 |
2023-08-12 |
Not clear |
| Yan Liu, Li I Zhang, Huizhong W Ta. Heterosynaptic scaling of developing GABAergic synapses: dependence on glutamatergic input and developmental stage. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 20. 2007-05-31. PMID:17507553. |
the induction of ltp requires the activation of postsynaptic nmda receptors, as well as presynaptic trkb signaling likely through retrograde bdnf (brain-derived neurotrophic factor) and is achieved by overcoming a predominant depression process mediated by nmda receptors on the presynaptic gabaergic neurons. |
2007-05-31 |
2023-08-12 |
xenopus_laevis |
| Christopher M Marano, Pornima Phatak, Ugandhar Rao Vemulapalli, Amritpal Sasan, Maria R Nalbandyan, Sailakshmi Ramanujam, Surjo Soekadar, Maria Demosthenous, William T Regenol. Increased plasma concentration of brain-derived neurotrophic factor with electroconvulsive therapy: a pilot study in patients with major depression. The Journal of clinical psychiatry. vol 68. issue 4. 2007-05-10. PMID:17474805. |
to investigate a neurotrophic effect in humans, we examined whether plasma concentration of brain-derived neurotrophic factor (bdnf) increases in patients receiving ect for major depression. |
2007-05-10 |
2023-08-12 |
Not clear |
| Renee F Ren-Patterson, Lauren W Cochran, Andrew Holmes, Klaus-Peter Lesch, Bai Lu, Dennis L Murph. Gender-dependent modulation of brain monoamines and anxiety-like behaviors in mice with genetic serotonin transporter and BDNF deficiencies. Cellular and molecular neurobiology. vol 26. issue 4-6. 2007-04-24. PMID:17029036. |
this double-mutant mouse model contributes to the knowledge base that will help in understanding genexgenexgender interactions in studies of sert and bdnf gene polymorphisms in human genetic diseases such as anxiety disorders and depression. |
2007-04-24 |
2023-08-12 |
mouse |
| Chi-Un Pa. Comments on "Low plasma BDNF is associated with suicidal behavior in major depression" by Y.K. Kim et al. Progress in Neuropsychopharmacology and Biological Psychiatry 2006 Aug 9; [Epub ahead of print]. Progress in neuro-psychopharmacology & biological psychiatry. vol 31. issue 2. 2007-04-24. PMID:17134810. |
comments on "low plasma bdnf is associated with suicidal behavior in major depression" by y.k. |
2007-04-24 |
2023-08-12 |
Not clear |
| Catharine H Duman, Lee Schlesinger, Masafumi Kodama, David S Russell, Ronald S Duma. A role for MAP kinase signaling in behavioral models of depression and antidepressant treatment. Biological psychiatry. vol 61. issue 5. 2007-04-17. PMID:16945347. |
brain-derived neurotrophic factor (bdnf) is upregulated in the hippocampus by antidepressant treatments, and centrally administered bdnf can produce antidepressant-like effects in rodent behavioral models of depression. |
2007-04-17 |
2023-08-12 |
Not clear |
| Yong-Ku Kim, Heung-Pyo Lee, Sung-Doo Won, Eun-Young Park, Hwa-Young Lee, Bun-Hee Lee, Sung-Woo Lee, Dokyung Yoon, Changsu Han, Dai-Jin Kim, So-Hyun Cho. Low plasma BDNF is associated with suicidal behavior in major depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 31. issue 1. 2007-03-15. PMID:16904252. |
low plasma bdnf is associated with suicidal behavior in major depression. |
2007-03-15 |
2023-08-12 |
Not clear |
| Yong-Ku Kim, Heung-Pyo Lee, Sung-Doo Won, Eun-Young Park, Hwa-Young Lee, Bun-Hee Lee, Sung-Woo Lee, Dokyung Yoon, Changsu Han, Dai-Jin Kim, So-Hyun Cho. Low plasma BDNF is associated with suicidal behavior in major depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 31. issue 1. 2007-03-15. PMID:16904252. |
brain-derived neurotrophic factor (bdnf), the most abundant neurotrophin in the brain, has a known association with the pathophysiology of anxiety and depression. |
2007-03-15 |
2023-08-12 |
Not clear |
| Yong-Ku Kim, Heung-Pyo Lee, Sung-Doo Won, Eun-Young Park, Hwa-Young Lee, Bun-Hee Lee, Sung-Woo Lee, Dokyung Yoon, Changsu Han, Dai-Jin Kim, So-Hyun Cho. Low plasma BDNF is associated with suicidal behavior in major depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 31. issue 1. 2007-03-15. PMID:16904252. |
the most suitable cut-off point of bdnf level between suicidal depression and non-suicidal depression groups was 444.58 pg/ml. |
2007-03-15 |
2023-08-12 |
Not clear |
| Yong-Ku Kim, Heung-Pyo Lee, Sung-Doo Won, Eun-Young Park, Hwa-Young Lee, Bun-Hee Lee, Sung-Woo Lee, Dokyung Yoon, Changsu Han, Dai-Jin Kim, So-Hyun Cho. Low plasma BDNF is associated with suicidal behavior in major depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 31. issue 1. 2007-03-15. PMID:16904252. |
these results suggest that reduction of plasma bdnf level is related to suicidal behavior in major depression and that bdnf level may be a biological marker of suicidal depression. |
2007-03-15 |
2023-08-12 |
Not clear |