| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Peter Pregelj, Gordana Nedic, Alja Videtič Paska, Tomaž Zupanc, Matea Nikolac, Jože Balažic, Martina Tomori, Radovan Komel, Dorotea Muck Seler, Nela Piva. The association between brain-derived neurotrophic factor polymorphism (BDNF Val66Met) and suicide. Journal of affective disorders. vol 128. issue 3. 2011-04-25. PMID:20667416. |
a functional bdnf polymorphism (bdnf val66met) was reported to influence the effects of stressful life events or childhood adversity on depression and suicidal behaviour in various psychopathologies. |
2011-04-25 |
2023-08-12 |
Not clear |
| Cliona M O'Mahony, Gerard Clarke, Sinead Gibney, Timothy G Dinan, John F Crya. Strain differences in the neurochemical response to chronic restraint stress in the rat: relevance to depression. Pharmacology, biochemistry, and behavior. vol 97. issue 4. 2011-04-25. PMID:21110995. |
moreover, decreases in serum levels of the neurotrophin brain-derived neurotrophic factor (bdnf) have led to the more recent neurotrophic hypothesis of depression. |
2011-04-25 |
2023-08-12 |
rat |
| Hui Yu, Zhe-yu Che. The role of BDNF in depression on the basis of its location in the neural circuitry. Acta pharmacologica Sinica. vol 32. issue 1. 2011-04-25. PMID:21131999. |
the role of bdnf in depression on the basis of its location in the neural circuitry. |
2011-04-25 |
2023-08-12 |
Not clear |
| Hui Yu, Zhe-yu Che. The role of BDNF in depression on the basis of its location in the neural circuitry. Acta pharmacologica Sinica. vol 32. issue 1. 2011-04-25. PMID:21131999. |
recently bdnf has been shown to play an important role in the pathophysiology of depression, however there are controversial reports about the effects of bdnf on depression. |
2011-04-25 |
2023-08-12 |
Not clear |
| Hui Yu, Zhe-yu Che. The role of BDNF in depression on the basis of its location in the neural circuitry. Acta pharmacologica Sinica. vol 32. issue 1. 2011-04-25. PMID:21131999. |
here, we present an overview of the current knowledge concerning bdnf actions and associated intracellular signaling in hippocampus, prefrontal cortex, nucleus accumbens (nac) and amygdala as their relation to depression. |
2011-04-25 |
2023-08-12 |
Not clear |
| Ian M Goodyer, Tim Croudace, Frank Dudbridge, Maria Ban, Joe Herber. Polymorphisms in BDNF (Val66Met) and 5-HTTLPR, morning cortisol and subsequent depression in at-risk adolescents. The British journal of psychiatry : the journal of mental science. vol 197. issue 5. 2011-04-08. PMID:21037213. |
polymorphisms in bdnf (val66met) and 5-httlpr, morning cortisol and subsequent depression in at-risk adolescents. |
2011-04-08 |
2023-08-12 |
Not clear |
| Elizabeth P Hayden, Daniel N Klein, Lea R Dougherty, Thomas M Olino, Margaret W Dyson, C Emily Durbin, Haroon I Sheikh, Shiva M Sing. The role of brain-derived neurotrophic factor genotype, parental depression, and relationship discord in predicting early-emerging negative emotionality. Psychological science. vol 21. issue 11. 2011-04-04. PMID:20921572. |
we therefore examined whether the single-nucleotide polymorphism producing a valine-to-methionine substitution at codon 66 (val66met) of the bdnf gene was associated with childhood ne, in the context of parental depression and relationship discord. |
2011-04-04 |
2023-08-12 |
Not clear |
| Neslihan Aygun Kocabas, Irina Antonijevic, Carole Faghel, Carlos Forray, Siegfried Kasper, Yves Lecrubier, Sylvie Linotte, Isabelle Massat, Julien Mendlewicz, Magali Noro, Stuart Montgomery, Pierre Oswald, Lenore Snyder, Joseph Zohar, Daniel Souer. Brain-derived neurotrophic factor gene polymorphisms: influence on treatment response phenotypes of major depressive disorder. International clinical psychopharmacology. vol 26. issue 1. 2011-03-18. PMID:21188787. |
two hundred and six patients with diagnostic and statistical manual of mental disorders-iv mdd were recruited for this study and genotyped for eight bdnf tagging snps (rs11030096, rs925946, rs10501087,rs6265, rs12273363, rs908867, rs1491850, and rs1491851)to investigate the functional impact of genotypes/haplotypes in the susceptibility of depression and on treatment response. |
2011-03-18 |
2023-08-12 |
Not clear |
| R H Kang, H S Chang, M L Wong, M J Choi, J Y Park, H Y Lee, I K Jung, S H Joe, L Kim, S H Kim, Y K Kim, C S Han, B J Ham, H J Lee, Y H Ko, M S Lee, M S Le. Brain-derived neurotrophic factor gene polymorphisms and mirtazapine responses in Koreans with major depression. Journal of psychopharmacology (Oxford, England). vol 24. issue 12. 2011-03-16. PMID:19493959. |
the reduction in the hamilton depression score over the 8-week treatment period was not influenced by bdnf v66m genotypes. |
2011-03-16 |
2023-08-12 |
human |
| Reiji Yoshimura, Atsuko Ikenouchi-Sugita, Hikaru Hori, Wakako Umene-Nakano, Asuka Katsuki, Kenji Hayashi, Kiyokazu Atake, Nobuhisa Ueda, Jun Nakamur. [Brain-derived neurotrophic factor (BDNF) and mood disorder]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 30. issue 5-6. 2011-03-08. PMID:21226313. |
these findings indicate that the blood bdnf level is one of the candidate biomarkers for depression. |
2011-03-08 |
2023-08-12 |
Not clear |
| Valeria Carola, Cornelius Gros. BDNF moderates early environmental risk factors for anxiety in mouse. Genes, brain, and behavior. vol 9. issue 4. 2011-02-18. PMID:20132316. |
a polymorphism in the brain-derived neurotrophic factor (bdnf) gene modulates the association between adverse early experiences and risk for anxiety and depression in adulthood. |
2011-02-18 |
2023-08-12 |
mouse |
| Liliana Dell'Osso, Alessandro Del Debbio, Antonello Veltri, Carolina Bianchi, Isabella Roncaglia, Marina Carlini, Gabriele Massimetti, Mario Catena Dell'Osso, Chiara Vizzaccaro, Donatella Marazziti, Armando Piccinn. Associations between brain-derived neurotrophic factor plasma levels and severity of the illness, recurrence and symptoms in depressed patients. Neuropsychobiology. vol 62. issue 4. 2011-02-14. PMID:20714169. |
the aim of the present study was to measure bdnf plasma levels in patients affected by major depression and to explore the possible relationship between the biological parameter and characteristics of the illness. |
2011-02-14 |
2023-08-12 |
Not clear |
| Betina Elfving, Pia Høgh Plougmann, Heidi Kaastrup Müller, Aleksander A Mathé, Raben Rosenberg, Gregers Wegene. Inverse correlation of brain and blood BDNF levels in a genetic rat model of depression. The international journal of neuropsychopharmacology. vol 13. issue 5. 2011-01-25. PMID:19796445. |
inverse correlation of brain and blood bdnf levels in a genetic rat model of depression. |
2011-01-25 |
2023-08-12 |
human |
| Betina Elfving, Pia Høgh Plougmann, Heidi Kaastrup Müller, Aleksander A Mathé, Raben Rosenberg, Gregers Wegene. Inverse correlation of brain and blood BDNF levels in a genetic rat model of depression. The international journal of neuropsychopharmacology. vol 13. issue 5. 2011-01-25. PMID:19796445. |
there is accumulating evidence that brain-derived neurotrophic factor (bdnf) plays a critical role in the pathophysiology of depression. |
2011-01-25 |
2023-08-12 |
human |
| Betina Elfving, Pia Høgh Plougmann, Heidi Kaastrup Müller, Aleksander A Mathé, Raben Rosenberg, Gregers Wegene. Inverse correlation of brain and blood BDNF levels in a genetic rat model of depression. The international journal of neuropsychopharmacology. vol 13. issue 5. 2011-01-25. PMID:19796445. |
these findings indicate parallel changes in brain and serum bdnf levels during depression. |
2011-01-25 |
2023-08-12 |
human |
| Betina Elfving, Pia Høgh Plougmann, Heidi Kaastrup Müller, Aleksander A Mathé, Raben Rosenberg, Gregers Wegene. Inverse correlation of brain and blood BDNF levels in a genetic rat model of depression. The international journal of neuropsychopharmacology. vol 13. issue 5. 2011-01-25. PMID:19796445. |
in investigations between flinders sensitive line (fsl) and flinders resistant line (frl) rats, a genetic rat model of depression, no differences were found in bdnf levels in the frontal cortex and hippocampus, areas believed to be core brain regions in depression. |
2011-01-25 |
2023-08-12 |
human |
| Betina Elfving, Pia Høgh Plougmann, Heidi Kaastrup Müller, Aleksander A Mathé, Raben Rosenberg, Gregers Wegene. Inverse correlation of brain and blood BDNF levels in a genetic rat model of depression. The international journal of neuropsychopharmacology. vol 13. issue 5. 2011-01-25. PMID:19796445. |
the differential regulation of the bdnf levels in hippocampus, serum, and whole blood in fsl/frl rats adds to the hypothesis that neurotrophic factors are related to the pathophysiology of depression. |
2011-01-25 |
2023-08-12 |
human |
| Hua-Cheng Yan, Hong-Da Qu, Li-Rong Sun, Shu-Ji Li, Xiong Cao, Ying-Ying Fang, Wei Jie, Jonathan C Bean, Wei-Kang Wu, Xin-Hong Zhu, Tian-Ming Ga. Fuzi polysaccharide-1 produces antidepressant-like effects in mice. The international journal of neuropsychopharmacology. vol 13. issue 5. 2011-01-25. PMID:19796446. |
finally, acute treatment with fps had no effect on brain monoamine levels in frontal cortex but significantly increases bdnf in the hippocampus, while the antidepressant effect and enhancement of cell proliferation induced by fps administration were totally blocked by k252a, an inhibitor of trkb in a chronic social defeat depression model, suggesting that the neurogenic and antidepressant effects of fps may involve bdnf signalling. |
2011-01-25 |
2023-08-12 |
mouse |
| Plínio Cabrera Casarotto, Valquiria Camin de Bortoli, Fernando Morgan de Aguiar Corrêa, Leonardo Barbosa Moraes Resstel, Hélio Zangross. Panicolytic-like effect of BDNF in the rat dorsal periaqueductal grey matter: the role of 5-HT and GABA. The international journal of neuropsychopharmacology. vol 13. issue 5. 2011-01-25. PMID:20047714. |
a wealth of evidence suggests a role for brain-derived neurotrophic factor (bdnf) and its receptor tropomyosin-related kinase b (trkb) in the aetiology of depression and in the mode of action of antidepressant drugs. |
2011-01-25 |
2023-08-12 |
rat |
| Christoph Laske, Sabine Banschbach, Elke Stransky, Sabine Bosch, Guido Straten, Jürgen Machann, Andreas Fritsche, Arno Hipp, Andreas Niess, Gerhard W Eschweile. Exercise-induced normalization of decreased BDNF serum concentration in elderly women with remitted major depression. The international journal of neuropsychopharmacology. vol 13. issue 5. 2011-01-25. PMID:20067661. |
exercise-induced normalization of decreased bdnf serum concentration in elderly women with remitted major depression. |
2011-01-25 |
2023-08-12 |
Not clear |