| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sven Pålhagen, Hongshi Qi, Björn Mårtensson, Jan Wålinder, Ann-Kathrine Granérus, Per Svenningsso. Monoamines, BDNF, IL-6 and corticosterone in CSF in patients with Parkinson's disease and major depression. Journal of neurology. vol 257. issue 4. 2010-06-23. PMID:19844754. |
monoamines, bdnf, il-6 and corticosterone in csf in patients with parkinson's disease and major depression. |
2010-06-23 |
2023-08-12 |
Not clear |
| Eero Castrén, Tomi Rantamäk. The role of BDNF and its receptors in depression and antidepressant drug action: Reactivation of developmental plasticity. Developmental neurobiology. vol 70. issue 5. 2010-06-23. PMID:20186711. |
the role of bdnf and its receptors in depression and antidepressant drug action: reactivation of developmental plasticity. |
2010-06-23 |
2023-08-12 |
Not clear |
| Eero Castrén, Tomi Rantamäk. The role of BDNF and its receptors in depression and antidepressant drug action: Reactivation of developmental plasticity. Developmental neurobiology. vol 70. issue 5. 2010-06-23. PMID:20186711. |
such observations suggest a central role for neuronal plasticity in depression and the antidepressant effect, and also implicate bdnf signaling as a mediator of this plasticity. |
2010-06-23 |
2023-08-12 |
Not clear |
| Eero Castrén, Tomi Rantamäk. The role of BDNF and its receptors in depression and antidepressant drug action: Reactivation of developmental plasticity. Developmental neurobiology. vol 70. issue 5. 2010-06-23. PMID:20186711. |
this review discusses recent data on the role of bdnf and its receptors in depression and the antidepressant response and suggests a model whereby the effects of antidepressant treatments could be explained by a reactivation of activity-dependent and bdnf-mediated cortical plasticity, which in turn leads to the adjustment of neuronal networks to better adapt to environmental challenges. |
2010-06-23 |
2023-08-12 |
Not clear |
| Neha J Patel, Michael J Chen, Amelia A Russo-Neustad. Norepinephrine and nitric oxide promote cell survival signaling in hippocampal neurons. European journal of pharmacology. vol 633. issue 1-3. 2010-06-22. PMID:20149790. |
nitric oxide (no), physical exercise and/or antidepressant drugs, through the increased release of norepinephrine and brain-derived neurotrophic factor (bdnf), have been shown to exert profound protective, pro-survival effects on neurons otherwise compromised by injury, disease, prolonged stress, and subsequent depression in vivo. |
2010-06-22 |
2023-08-12 |
Not clear |
| Barbara Borroni, Chiara Costanzi, Alessandro Padovan. Genetic susceptibility to behavioural and psychological symptoms in Alzheimer disease. Current Alzheimer research. vol 7. issue 2. 2010-06-21. PMID:19715553. |
moreover, genetic variations of neurotrophins, such as brain-derived neurotrophic factor (bdnf), have been related to depression susceptibility in ad. |
2010-06-21 |
2023-08-12 |
Not clear |
| R Molteni, F Calabrese, S Chourbaji, C Brandwein, G Racagni, P Gass, M A Riv. Depression-prone mice with reduced glucocorticoid receptor expression display an altered stress-dependent regulation of brain-derived neurotrophic factor and activity-regulated cytoskeleton-associated protein. Journal of psychopharmacology (Oxford, England). vol 24. issue 4. 2010-06-18. PMID:19074532. |
specifically, we have analysed the neurotrophin brain-derived neurotrophic factor (bdnf) and the immediate-early gene activity-regulated cytoskeletal-associated protein (arc), two closely related molecules that can contribute to neuroplastic and morphological changes observed in depression. |
2010-06-18 |
2023-08-12 |
mouse |
| Raffaella Molteni, Annamaria Cattaneo, Francesca Calabrese, Flavia Macchi, Jocelien D A Olivier, Giorgio Racagni, Bart A Ellenbroek, Massimo Gennarelli, Marco A Riv. Reduced function of the serotonin transporter is associated with decreased expression of BDNF in rodents as well as in humans. Neurobiology of disease. vol 37. issue 3. 2010-06-08. PMID:20034565. |
in order to identify the molecular mechanisms that may contribute to the enhanced susceptibility to depression under serotonin transporter (sert) dysfunction, we analyzed the expression of brain-derived neurotrophic factor (bdnf), a key player in neuronal plasticity, which is implicated in the etiology and treatment of depression. |
2010-06-08 |
2023-08-12 |
human |
| Guido van Wingen, Mark Rijpkema, Barbara Franke, Philip van Eijndhoven, Indira Tendolkar, Robbert Jan Verkes, Jan Buitelaar, Guillén Fernánde. The brain-derived neurotrophic factor Val66Met polymorphism affects memory formation and retrieval of biologically salient stimuli. NeuroImage. vol 50. issue 3. 2010-06-08. PMID:20097294. |
a single nucleotide polymorphism in the human bdnf gene (val66met) affects memory, and influences alzheimer's disease and depression vulnerability in a sex-specific manner. |
2010-06-08 |
2023-08-12 |
human |
| Guido van Wingen, Mark Rijpkema, Barbara Franke, Philip van Eijndhoven, Indira Tendolkar, Robbert Jan Verkes, Jan Buitelaar, Guillén Fernánde. The brain-derived neurotrophic factor Val66Met polymorphism affects memory formation and retrieval of biologically salient stimuli. NeuroImage. vol 50. issue 3. 2010-06-08. PMID:20097294. |
furthermore, the sex-specific genotype effects may contribute to sex-specific effects of bdnf val66met on depression vulnerability. |
2010-06-08 |
2023-08-12 |
human |
| Sophiya Benjamin, Douglas R McQuoid, Guy G Potter, Martha E Payne, James R MacFall, David C Steffens, Warren D Taylo. The brain-derived neurotrophic factor Val66Met polymorphism, hippocampal volume, and cognitive function in geriatric depression. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 18. issue 4. 2010-06-03. PMID:20220593. |
the val66met polymorphism of the brain-derived neurotrophic factor (bdnf) gene is associated with geriatric depression. |
2010-06-03 |
2023-08-12 |
Not clear |
| Francesca Calabrese, Raffaella Molteni, Annamaria Cattaneo, Flavia Macchi, Giorgio Racagni, Massimo Gennarelli, Bart A Ellenbroek, Marco A Riv. Long-Term duloxetine treatment normalizes altered brain-derived neurotrophic factor expression in serotonin transporter knockout rats through the modulation of specific neurotrophin isoforms. Molecular pharmacology. vol 77. issue 5. 2010-05-28. PMID:20159945. |
we have demonstrated recently that sert knockout (ko) rats, generated by n-ethyl-n-nitrosourea-induced mutagenesis, show reduced expression of the neurotrophin brain-derived neurotrophic factor (bdnf) in the hippocampus and prefrontal cortex, suggesting that depression vulnerability can be associated with impaired neuronal plasticity. |
2010-05-28 |
2023-08-12 |
rat |
| M Verhagen, A van der Meij, P A M van Deurzen, J G E Janzing, A Arias-Vásquez, J K Buitelaar, B Frank. Meta-analysis of the BDNF Val66Met polymorphism in major depressive disorder: effects of gender and ethnicity. Molecular psychiatry. vol 15. issue 3. 2010-05-11. PMID:18852698. |
in the total sample, the bdnf val66met polymorphism was not significantly associated with depression. |
2010-05-11 |
2023-08-12 |
Not clear |
| Andreas Ströhle, Meline Stoy, Barbara Graetz, Michael Scheel, André Wittmann, Jürgen Gallinat, Undine E Lang, Fernando Dimeo, Rainer Hellwe. Acute exercise ameliorates reduced brain-derived neurotrophic factor in patients with panic disorder. Psychoneuroendocrinology. vol 35. issue 3. 2010-05-07. PMID:19682803. |
the neurotrophin brain-derived neurotrophic factor (bdnf) has been implicated in depression and anxiety. |
2010-05-07 |
2023-08-12 |
human |
| M V Alfimova, V E Golimbet, A N Barkhatova, S A Golubev, G I Korovaĭtsev. [The role of genotype-environment interactions in the development of symptoms of anxiety and depression related to the disease burden for family]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova. vol 109. issue 12. 2010-04-20. PMID:20037522. |
the association of 5-httlpr and val66met bdnf genotypes with symptoms of anxiety and depression related to stress caused by severe chronic psychiatric disease of a family member has been studied. |
2010-04-20 |
2023-08-12 |
Not clear |
| Atsuko Ikenouchi-Sugita, Yumiko Toyohira, Reiji Yoshimura, Susumu Ueno, Masato Tsutsui, Jun Nakamura, Nobuyuki Yanagihar. Opposite effects of milnacipran, a serotonin norepinephrine reuptake inhibitor, on the levels of nitric oxide and brain-derived neurotrophic factor in mouse brain cortex. Naunyn-Schmiedeberg's archives of pharmacology. vol 380. issue 6. 2010-03-30. PMID:19894036. |
there is a growing body of evidence demonstrating that changes in the brain levels of nitric oxide (no) and brain-derived neurotrophic factor (bdnf) are implicated in the pathogenesis of major depression. |
2010-03-30 |
2023-08-12 |
mouse |
| Filippo Caraci, Agata Copani, Ferdinando Nicoletti, Filippo Drag. Depression and Alzheimer's disease: neurobiological links and common pharmacological targets. European journal of pharmacology. vol 626. issue 1. 2010-03-26. PMID:19837057. |
in particular, a specific impairment in the signaling of some neurotrophins such as transforming-growth-factor beta1 (tgf-beta1) and brain-derived neurotrophic factor (bdnf) has been observed both in depression and alzheimer's disease. |
2010-03-26 |
2023-08-12 |
Not clear |
| Katharina Domschke, Bruce Lawford, Gonzalo Laje, Klaus Berger, Ross Young, Phillip Morris, Jürgen Deckert, Volker Arolt, Francis J McMahon, Bernhard T Baun. Brain-derived neurotrophic factor ( BDNF) gene: no major impact on antidepressant treatment response. The international journal of neuropsychopharmacology. vol 13. issue 1. 2010-03-23. PMID:19236730. |
in order to further clarify the impact of bdnf gene variation on major depression as well as antidepressant treatment response, association of three bdnf polymorphisms [rs7103411, val66met (rs6265) and rs7124442] with major depression and antidepressant treatment response was investigated in an overall sample of 268 german patients with major depression and 424 healthy controls. |
2010-03-23 |
2023-08-12 |
Not clear |
| Katharina Domschke, Bruce Lawford, Gonzalo Laje, Klaus Berger, Ross Young, Phillip Morris, Jürgen Deckert, Volker Arolt, Francis J McMahon, Bernhard T Baun. Brain-derived neurotrophic factor ( BDNF) gene: no major impact on antidepressant treatment response. The international journal of neuropsychopharmacology. vol 13. issue 1. 2010-03-23. PMID:19236730. |
while bdnf was not associated with major depression as a categorical diagnosis, the bdnf rs7124442 tt genotype was significantly related to worse treatment outcome over 6 wk in major depression (p = 0.01) particularly in anxious depression (p = 0.003) in the german sample. |
2010-03-23 |
2023-08-12 |
Not clear |
| Katharina Domschke, Bruce Lawford, Gonzalo Laje, Klaus Berger, Ross Young, Phillip Morris, Jürgen Deckert, Volker Arolt, Francis J McMahon, Bernhard T Baun. Brain-derived neurotrophic factor ( BDNF) gene: no major impact on antidepressant treatment response. The international journal of neuropsychopharmacology. vol 13. issue 1. 2010-03-23. PMID:19236730. |
however, bdnf rs7103411 and rs6265 similarly predicted worse treatment response over 6 wk in clinical subtypes of depression such as melancholic depression only (rs7103411: tt < cc, p = 0.003; rs6265: gg < aa, p = 0.001). |
2010-03-23 |
2023-08-12 |
Not clear |