| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Terracciano, B Martin, D Ansari, T Tanaka, L Ferrucci, S Maudsley, M P Mattson, P T Cost. Plasma BDNF concentration, Val66Met genetic variant and depression-related personality traits. Genes, brain, and behavior. vol 9. issue 5. 2010-11-15. PMID:20345896. |
however, in men, but not in women, bdnf plasma level was associated with personality traits linked to depression. |
2010-11-15 |
2023-08-12 |
Not clear |
| A Terracciano, B Martin, D Ansari, T Tanaka, L Ferrucci, S Maudsley, M P Mattson, P T Cost. Plasma BDNF concentration, Val66Met genetic variant and depression-related personality traits. Genes, brain, and behavior. vol 9. issue 5. 2010-11-15. PMID:20345896. |
contrary to the notion that low bdnf is associated with negative outcomes, we found lower plasma levels in men who score lower on depression and vulnerability to stress (two facets of neuroticism) and higher on conscientiousness and extraversion. |
2010-11-15 |
2023-08-12 |
Not clear |
| A Terracciano, B Martin, D Ansari, T Tanaka, L Ferrucci, S Maudsley, M P Mattson, P T Cost. Plasma BDNF concentration, Val66Met genetic variant and depression-related personality traits. Genes, brain, and behavior. vol 9. issue 5. 2010-11-15. PMID:20345896. |
these findings challenge the prevailing hypothesis that lower peripheral levels of bdnf are a marker of depression. |
2010-11-15 |
2023-08-12 |
Not clear |
| Kenji Hashimot. Brain-derived neurotrophic factor as a biomarker for mood disorders: an historical overview and future directions. Psychiatry and clinical neurosciences. vol 64. issue 4. 2010-11-09. PMID:20653908. |
in 2003, we reported that serum levels of bdnf in antidepressant-naive patients with mdd were significantly lower than those of patients medicated with antidepressants and normal controls, and that serum bdnf levels were negatively correlated with the severity of depression. |
2010-11-09 |
2023-08-12 |
Not clear |
| Kenji Hashimot. Brain-derived neurotrophic factor as a biomarker for mood disorders: an historical overview and future directions. Psychiatry and clinical neurosciences. vol 64. issue 4. 2010-11-09. PMID:20653908. |
additionally, we found that decreased serum levels of bdnf in antidepressant-naive patients recovered to normal levels associated with the recovery of depression after treatment with antidepressant medication. |
2010-11-09 |
2023-08-12 |
Not clear |
| Andre Russowsky Brunoni, Roberta Monterazzo Cysneiro. Lower mRNA BDNF expression in lymphocytes: endophenotype or epiphenomenon for major depression? Progress in neuro-psychopharmacology & biological psychiatry. vol 34. issue 6. 2010-11-02. PMID:20438792. |
lower mrna bdnf expression in lymphocytes: endophenotype or epiphenomenon for major depression? |
2010-11-02 |
2023-08-12 |
Not clear |
| Wen-Jing Li, Hui Yu, Jian-Min Yang, Jing Gao, Hong Jiang, Min Feng, Yu-Xia Zhao, Zhe-Yu Che. Anxiolytic effect of music exposure on BDNFMet/Met transgenic mice. Brain research. vol 1347. 2010-11-02. PMID:20515664. |
recently, a single nucleotide polymorphism (snp) in the bdnf gene (val66met) has been found to be associated with depression and anxiety disorders. |
2010-11-02 |
2023-08-12 |
mouse |
| Yanyan Shi, Jiayong You, Yonggui Yuan, Xiangrong Zhang, Hailin Li, Gang Ho. Plasma BDNF and tPA are associated with late-onset geriatric depression. Psychiatry and clinical neurosciences. vol 64. issue 3. 2010-10-19. PMID:20602725. |
plasma bdnf and tpa are associated with late-onset geriatric depression. |
2010-10-19 |
2023-08-12 |
Not clear |
| Christian Montag, Ulrike Basten, Christine Stelzel, Christian J Fiebach, Martin Reute. The BDNF Val66Met polymorphism and anxiety: support for animal knock-in studies from a genetic association study in humans. Psychiatry research. vol 179. issue 1. 2010-10-12. PMID:20478625. |
mounting evidence shows that the brain derived neurotrophic factor (bdnf) plays a crucial role in depression and anxiety. |
2010-10-12 |
2023-08-12 |
mouse |
| Enrico Domenici, David R Willé, Federica Tozzi, Inga Prokopenko, Sam Miller, Astrid McKeown, Claire Brittain, Dan Rujescu, Ina Giegling, Christoph W Turck, Florian Holsboer, Edward T Bullmore, Lefkos Middleton, Emilio Merlo-Pich, Robert C Alexander, Pierandrea Mugli. Plasma protein biomarkers for depression and schizophrenia by multi analyte profiling of case-control collections. PloS one. vol 5. issue 2. 2010-09-30. PMID:20161799. |
univariate data analysis showed more significant p-values than would be expected by chance and highlighted several proteins belonging to pathways or mechanisms previously suspected to be involved in the pathophysiology of major depression or schizophrenia, such as insulin and mmp-9 for depression, and bdnf, egf and a number of chemokines for schizophrenia. |
2010-09-30 |
2023-08-12 |
Not clear |
| Barbara Borroni, Mario Grassi, Silvana Archetti, Chiara Costanzi, Marta Bianchi, Luigi Caimi, Carlo Caltagirone, Monica Di Luca, Alessandro Padovan. BDNF genetic variations increase the risk of Alzheimer's disease-related depression. Journal of Alzheimer's disease : JAD. vol 18. issue 4. 2010-09-16. PMID:19661618. |
bdnf genetic variations increase the risk of alzheimer's disease-related depression. |
2010-09-16 |
2023-08-12 |
Not clear |
| Barbara Borroni, Mario Grassi, Silvana Archetti, Chiara Costanzi, Marta Bianchi, Luigi Caimi, Carlo Caltagirone, Monica Di Luca, Alessandro Padovan. BDNF genetic variations increase the risk of Alzheimer's disease-related depression. Journal of Alzheimer's disease : JAD. vol 18. issue 4. 2010-09-16. PMID:19661618. |
the gene encoding the brain-derived neurotrophic factor (bdnf) has been demonstrated as a candidate for alzheimer's disease-related depression (ad-d) susceptibility. |
2010-09-16 |
2023-08-12 |
Not clear |
| Barbara Borroni, Mario Grassi, Silvana Archetti, Chiara Costanzi, Marta Bianchi, Luigi Caimi, Carlo Caltagirone, Monica Di Luca, Alessandro Padovan. BDNF genetic variations increase the risk of Alzheimer's disease-related depression. Journal of Alzheimer's disease : JAD. vol 18. issue 4. 2010-09-16. PMID:19661618. |
this study suggests that bdnf genetic variations play a role in the susceptibility to ad-related depression. |
2010-09-16 |
2023-08-12 |
Not clear |
| Susana Aznar, Anders B Klein, Martin A Santini, Gitte M Knudsen, Fritz Henn, Peter Gass, Barbara Vollmay. Aging and depression vulnerability interaction results in decreased serotonin innervation associated with reduced BDNF levels in hippocampus of rats bred for learned helplessness. Synapse (New York, N.Y.). vol 64. issue 7. 2010-09-08. PMID:20222154. |
aging and depression vulnerability interaction results in decreased serotonin innervation associated with reduced bdnf levels in hippocampus of rats bred for learned helplessness. |
2010-09-08 |
2023-08-12 |
rat |
| Susana Aznar, Anders B Klein, Martin A Santini, Gitte M Knudsen, Fritz Henn, Peter Gass, Barbara Vollmay. Aging and depression vulnerability interaction results in decreased serotonin innervation associated with reduced BDNF levels in hippocampus of rats bred for learned helplessness. Synapse (New York, N.Y.). vol 64. issue 7. 2010-09-08. PMID:20222154. |
both reduced hippocampal serotonin neurotransmission and brain-derived neurotrophic factor (bdnf) levels have been associated with increased depression vulnerability and are also regulated during aging. |
2010-09-08 |
2023-08-12 |
rat |
| Patrícia Figueira, Leandro Malloy-Diniz, Simone B Campos, Débora M Miranda, Marco Aurélio Romano-Silva, Luiz De Marco, Fernando S Neves, Humberto Corre. An association study between the Val66Met polymorphism of the BDNF gene and postpartum depression. Archives of women's mental health. vol 13. issue 3. 2010-08-26. PMID:20169377. |
an association study between the val66met polymorphism of the bdnf gene and postpartum depression. |
2010-08-26 |
2023-08-12 |
human |
| Yong Li, Gaston Calfa, Takafumi Inoue, Michelle D Amaral, Lucas Pozzo-Mille. Activity-dependent release of endogenous BDNF from mossy fibers evokes a TRPC3 current and Ca2+ elevations in CA3 pyramidal neurons. Journal of neurophysiology. vol 103. issue 5. 2010-08-25. PMID:20220070. |
this depression of nmdar-mediated epscs required activity-dependent release of endogenous bdnf from mfs and activation of trk receptors, as it was sensitive to the extracellular bdnf scavenger trkb-igg and the tyrosine kinase inhibitor k-252b. |
2010-08-25 |
2023-08-12 |
Not clear |
| Ghanshyam N Pandey, Yogesh Dwivedi, Hooriyah S Rizavi, Xinguo Ren, Hui Zhang, Mani N Pavulur. Brain-derived neurotrophic factor gene and protein expression in pediatric and adult depressed subjects. Progress in neuro-psychopharmacology & biological psychiatry. vol 34. issue 4. 2010-07-30. PMID:20227453. |
abnormalities of bdnf have been implicated in the pathophysiology of depression based on observations that antidepressant drugs cause increases in the levels of bdnf in rat brains and its abnormalities have appeared in the serum of depressed patients and in postmortem brains of suicide victims. |
2010-07-30 |
2023-08-12 |
human |
| Lisete Haas, Luis V C Portela, Ana Elisa Böhmer, Jean Pierre Oses, Diogo R Lar. Increased plasma levels of brain derived neurotrophic factor (BDNF) in patients with fibromyalgia. Neurochemical research. vol 35. issue 5. 2010-07-08. PMID:20119637. |
bdnf appears to modulate nociceptive sensory inputs and pain hypersensitivity and has been studied in pathological situations, including chronic pain conditions and major depression. |
2010-07-08 |
2023-08-12 |
human |
| Lisete Haas, Luis V C Portela, Ana Elisa Böhmer, Jean Pierre Oses, Diogo R Lar. Increased plasma levels of brain derived neurotrophic factor (BDNF) in patients with fibromyalgia. Neurochemical research. vol 35. issue 5. 2010-07-08. PMID:20119637. |
our results confirm previous findings of increased plasma bdnf levels in patients with fm, suggesting that bdnf may be involved in the pathophysiology of fibromyalgia, despite high levels of depression. |
2010-07-08 |
2023-08-12 |
human |