| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Stocker, L Perna, K Weigl, T Möllers, B Schöttker, H Thomsen, B Holleczek, D Rujescu, H Brenne. Correction: Prediction of clinical diagnosis of Alzheimer's disease, vascular, mixed, and all-cause dementia by a polygenic risk score and APOE status in a community-based cohort prospectively followed over 17 years. Molecular psychiatry. 2021-10-02. PMID:34599279. |
correction: prediction of clinical diagnosis of alzheimer's disease, vascular, mixed, and all-cause dementia by a polygenic risk score and apoe status in a community-based cohort prospectively followed over 17 years. |
2021-10-02 |
2023-08-13 |
Not clear |
| Jung-Min Pyun, Young Ho Park, Keon-Joo Lee, SangYun Kim, Andrew J Saykin, Kwangsik Nh. Predictability of polygenic risk score for progression to dementia and its interaction with APOE ε4 in mild cognitive impairment. Translational neurodegeneration. vol 10. issue 1. 2021-09-23. PMID:34465370. |
predictability of polygenic risk score for progression to dementia and its interaction with apoe ε4 in mild cognitive impairment. |
2021-09-23 |
2023-08-13 |
Not clear |
| Yen Ying Lim, Matthew P Pase, Rachel F Buckley, Nawaf Yassi, Lisa Bransby, Christopher Fowler, Simon M Laws, Colin L Masters, Paul Maruf. Visual Memory Deficits in Middle-Aged APOEɛ4 Homozygotes Detected Using Unsupervised Cognitive Assessments. Journal of Alzheimer's disease : JAD. vol 79. issue 4. 2021-09-15. PMID:33492293. |
the apolipoprotein e (apoe) ɛ4 allele is associated with dose-response effects on cognitive dysfunction and dementia risk in older adults. |
2021-09-15 |
2023-08-13 |
Not clear |
| Kylie R Kadey, John L Woodard, Allison C Moll, Kristy A Nielson, J Carson Smith, Sally Durgerian, Stephen M Ra. Five-Year Change in Body Mass Index Predicts Conversion to Mild Cognitive Impairment or Dementia Only in APOE ɛ4 Allele Carriers. Journal of Alzheimer's disease : JAD. vol 81. issue 1. 2021-09-15. PMID:33749649. |
five-year change in body mass index predicts conversion to mild cognitive impairment or dementia only in apoe ɛ4 allele carriers. |
2021-09-15 |
2023-08-13 |
Not clear |
| Kylie R Kadey, John L Woodard, Allison C Moll, Kristy A Nielson, J Carson Smith, Sally Durgerian, Stephen M Ra. Five-Year Change in Body Mass Index Predicts Conversion to Mild Cognitive Impairment or Dementia Only in APOE ɛ4 Allele Carriers. Journal of Alzheimer's disease : JAD. vol 81. issue 1. 2021-09-15. PMID:33749649. |
body mass index (bmi) has been identified as an important modifiable lifestyle risk factor for dementia, but less is known about how bmi might interact with apolipoprotein e ɛ4 (apoe ɛ4) carrier status to predict conversion to mild cognitive impairment (mci) and dementia. |
2021-09-15 |
2023-08-13 |
Not clear |
| Tamara Shiner, Anat Mirelman, Yevgenia Rosenblum, Gitit Kavé, Mali Gana Weisz, Anat Bar-Shira, Orly Goldstein, Avner Thaler, Tanya Gurevich, Avi Orr-Urtreger, Nir Giladi, Noa Bregma. The Effect of GBA Mutations and APOE Polymorphisms on Dementia with Lewy Bodies in Ashkenazi Jews. Journal of Alzheimer's disease : JAD. vol 80. issue 3. 2021-09-14. PMID:33646158. |
the effect of gba mutations and apoe polymorphisms on dementia with lewy bodies in ashkenazi jews. |
2021-09-14 |
2023-08-13 |
Not clear |
| Tamara Shiner, Anat Mirelman, Yevgenia Rosenblum, Gitit Kavé, Mali Gana Weisz, Anat Bar-Shira, Orly Goldstein, Avner Thaler, Tanya Gurevich, Avi Orr-Urtreger, Nir Giladi, Noa Bregma. The Effect of GBA Mutations and APOE Polymorphisms on Dementia with Lewy Bodies in Ashkenazi Jews. Journal of Alzheimer's disease : JAD. vol 80. issue 3. 2021-09-14. PMID:33646158. |
glucocerebrosidase (gba) gene mutations and apoe polymorphisms are common in dementia with lewy bodies (dlb), however their clinical impact is only partially elucidated. |
2021-09-14 |
2023-08-13 |
Not clear |
| Young-Gun Lee, Mincheol Park, Seong Ho Jeong, Sung Woo Kang, Kyoungwon Baik, Jin Ho Jung, Phil Hyu Lee, Young Ho Sohn, Byoung Seok Y. Effects of baseline serum uric acid and apolipoprotein E4 on longitudinal cognition and cerebral metabolism. Neurobiology of aging. vol 106. 2021-09-14. PMID:34311431. |
to investigate the effect of serum uric acid on longitudinal cognitive and brain metabolic changes, we utilized data on baseline serum uric acid levels, apoe genotyping, and longitudinal cognitive scores from the alzheimer's disease neuroimaging initiative for 1,343 participants with normal cognition (nc), mild cognitive impairment (mci), or dementia. |
2021-09-14 |
2023-08-13 |
human |
| Jesus D Melgarejo, Daniel C Aguirre-Acevedo, Ciro Gaona, Carlos A Chavez, Gustavo E Calmón, Eglé R Silva, Gabriel A de Erausquin, Mario Gil, Luis J Mena, Joseph D Terwilliger, Humberto Arboleda, Nikolaos Scarmeas, Joseph H Lee, Gladys E Maestr. Nighttime Blood Pressure Interacts with APOE Genotype to Increase the Risk of Incident Dementia of the Alzheimer's Type in Hispanics. Journal of Alzheimer's disease : JAD. vol 77. issue 2. 2021-09-09. PMID:32675415. |
nighttime blood pressure interacts with apoe genotype to increase the risk of incident dementia of the alzheimer's type in hispanics. |
2021-09-09 |
2023-08-13 |
Not clear |
| Seong Hee Ho, Dong-Won Yan. Risk Factors Predicting Amyloid PET Positivity in Patients with Mild Cognitive Impairment and Apolipoprotein E ɛ3/ɛ3 Genotypes. Journal of Alzheimer's disease : JAD. vol 77. issue 3. 2021-09-09. PMID:32804143. |
the apolipoprotein e (apoe) ɛ4 allele is a well-known risk factor for ad and is associated with higher amyloid deposition and earlier dementia onset. |
2021-09-09 |
2023-08-13 |
Not clear |
| Eleni Palpatzis, Nick Bass, Rebecca Jones, Naaheed Mukada. Longitudinal association of apolipoprotein E and sleep with incident dementia. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2021-09-03. PMID:34477303. |
few longitudinal studies have explored the association between apolipoprotein e gene (apoe) status, sleep disturbances, and incident dementia among middle-aged participants. |
2021-09-03 |
2023-08-13 |
human |
| Xiaoqi Wang, Weijie Huang, Li Su, Yue Xing, Frank Jessen, Yu Sun, Ni Shu, Ying Ha. Neuroimaging advances regarding subjective cognitive decline in preclinical Alzheimer's disease. Molecular neurodegeneration. vol 15. issue 1. 2021-08-26. PMID:32962744. |
additionally, the interaction of scd with other risk factors for dementia due to ad, such as age and the apolipoprotein e (apoe) ɛ4 status, has also been described. |
2021-08-26 |
2023-08-13 |
Not clear |
| Michael Tran Duong, Ilya M Nasrallah, David A Wolk, Catherine C Y Chang, Ta-Yuan Chan. Cholesterol, Atherosclerosis, and APOE in Vascular Contributions to Cognitive Impairment and Dementia (VCID): Potential Mechanisms and Therapy. Frontiers in aging neuroscience. vol 13. 2021-08-14. PMID:33841127. |
cholesterol, atherosclerosis, and apoe in vascular contributions to cognitive impairment and dementia (vcid): potential mechanisms and therapy. |
2021-08-14 |
2023-08-13 |
Not clear |
| John L Robinson, Hayley Richardson, Sharon X Xie, EunRan Suh, Vivianna M Van Deerlin, Brian Alfaro, Nicholas Loh, Matias Porras-Paniagua, Jeffrey J Nirschl, David Wolk, Virginia M-Y Lee, Edward B Lee, John Q Trojanowsk. The development and convergence of co-pathologies in Alzheimer's disease. Brain : a journal of neurology. vol 144. issue 3. 2021-08-13. PMID:33449993. |
to investigate how plaques, tangles, age and apolipoprotein e ε4 (apoe ε4) interact with co-pathologies in alzheimer's disease, we analysed 522 participants ≥50 years of age with and without dementia from the center for neurodegenerative disease research (cndr) autopsy program and 1340 participants in the national alzheimer's coordinating center (nacc) database. |
2021-08-13 |
2023-08-13 |
human |
| Katherine J Bangen, Denis S Smirnov, Lisa Delano-Wood, Christina E Wierenga, Mark W Bondi, David P Salmon, Douglas Galask. Arterial stiffening acts synergistically with APOE genotype and AD biomarker status to influence memory in older adults without dementia. Alzheimer's research & therapy. vol 13. issue 1. 2021-08-13. PMID:34210365. |
arterial stiffening acts synergistically with apoe genotype and ad biomarker status to influence memory in older adults without dementia. |
2021-08-13 |
2023-08-13 |
Not clear |
| Alexandre Bejanin, Maria Florencia Iulita, Eduard Vilaplana, Maria Carmona-Iragui, Bessy Benejam, Laura Videla, Isabel Barroeta, Susana Fernandez, Miren Altuna, Jordi Pegueroles, Victor Montal, Silvia Valldeneu, Sandra Giménez, Sofía González-Ortiz, Laia Muñoz, Concepción Padilla, Mateus Rozalem Aranha, Teresa Estellés, Ignacio Illán-Gala, Olivia Belbin, Valle Camacho, Liam Reese Wilson, Tiina Annus, Ricardo S Osorio, Sebastián Videla, Sylvain Lehmann, Anthony J Holland, Henrik Zetterberg, Kaj Blennow, Daniel Alcolea, Jordi Clarimon, Shahid H Zaman, Rafael Blesa, Alberto Lleó, Juan Forte. Association of Apolipoprotein E ɛ4 Allele With Clinical and Multimodal Biomarker Changes of Alzheimer Disease in Adults With Down Syndrome. JAMA neurology. vol 78. issue 8. 2021-08-13. PMID:34228042. |
previous studies have suggested that the apoe ɛ4 allele plays a role in the risk and age at onset of dementia in ds; however, data on in vivo biomarkers remain scarce. |
2021-08-13 |
2023-08-13 |
Not clear |
| Jenna Najar, Sven J van der Lee, Erik Joas, Hanna Wetterberg, John Hardy, Rita Guerreiro, Jose Bras, Margda Waern, Silke Kern, Henrik Zetterberg, Kaj Blennow, Ingmar Skoog, Anna Zettergre. Polygenic risk scores for Alzheimer's disease are related to dementia risk in APOE ɛ4 negatives. Alzheimer's & dementia (Amsterdam, Netherlands). vol 13. issue 1. 2021-08-06. PMID:33532541. |
polygenic risk scores for alzheimer's disease are related to dementia risk in apoe ɛ4 negatives. |
2021-08-06 |
2023-08-13 |
Not clear |
| Xiaowei Ma, Jun Ma, Ruiyun Guo, Juan Du, Baofeng Feng, Xin Liu, Xiaofeng Du, Zhenhuan Ma, Huixian Cu. Blood-derived integration-free induced pluripotent stem cells (iPSCs) from one 53-years-old male donor with APOE-ε4/ε4 genotype. Stem cell research. vol 54. 2021-08-05. PMID:34218115. |
apolipoprotein e ε4 allele (apoe4) is a minor allele of the apoe gene associated with a higher risk for alzheimer's disease (ad) and vascular dementia (vd). |
2021-08-05 |
2023-08-13 |
Not clear |
| Megan C Bakeberg, Anastazja M Gorecki, Abigail L Pfaff, Madison E Hoes, Sulev Kõks, P Anthony Akkari, Frank L Mastaglia, Ryan S Anderto. TOMM40 '523' poly-T repeat length is a determinant of longitudinal cognitive decline in Parkinson's disease. NPJ Parkinson's disease. vol 7. issue 1. 2021-07-24. PMID:34234128. |
however, in apoe ε3/ε3 carriers, who accounted for ~60% of the whole cohort, carriage of shorter '523' alleles was associated with more severe cognitive decline in both sexes, while carriage of the longer alleles in females were associated with better preservation of global cognition and a number of cognitive sub-domains, and with a delay in progression to dementia. |
2021-07-24 |
2023-08-13 |
Not clear |
| Megan C Bakeberg, Anastazja M Gorecki, Abigail L Pfaff, Madison E Hoes, Sulev Kõks, P Anthony Akkari, Frank L Mastaglia, Ryan S Anderto. TOMM40 '523' poly-T repeat length is a determinant of longitudinal cognitive decline in Parkinson's disease. NPJ Parkinson's disease. vol 7. issue 1. 2021-07-24. PMID:34234128. |
the findings indicate that when taken in conjunction with the apoe genotype, tomm40 '523' allele length is a significant independent determinant and marker for the trajectory of cognitive decline and risk of dementia in pd. |
2021-07-24 |
2023-08-13 |
Not clear |