| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hao Ma, Tao Zhou, Xiang Li, Demetrius Maraganore, Yoriko Heianza, Lu Q. Early-life educational attainment, APOE ε4 alleles, and incident dementia risk in late life. GeroScience. 2022-03-20. PMID:35306636. |
in addition, we observed that the dementia risk associated with a combination of low educational attainment and high apoe ε4-related genetic risk was more than the addition of the risk associated with each of these factors (p for additive interaction < 0.001). |
2022-03-20 |
2023-08-13 |
human |
| Hao Ma, Tao Zhou, Xiang Li, Demetrius Maraganore, Yoriko Heianza, Lu Q. Early-life educational attainment, APOE ε4 alleles, and incident dementia risk in late life. GeroScience. 2022-03-20. PMID:35306636. |
we found similar significant interactions between educational attainment and prs on both the multiplicative and additive scales on the dementia risk, mainly driven by the apoe genotype. |
2022-03-20 |
2023-08-13 |
human |
| Bethany M Coad, Parisa A Ghomroudi, Rebecca Sims, John P Aggleton, Seralynne D Vann, Claudia Metzler-Baddele. Apolipoprotein ε4 modifies obesity-related atrophy in the hippocampal formation of cognitively healthy adults. Neurobiology of aging. vol 113. 2022-03-18. PMID:35303671. |
obesity led to reductions in myelin/neurite packing and size/complexity regardless of apoe and family history of dementia status. |
2022-03-18 |
2023-08-13 |
Not clear |
| Yuka A Martens, Na Zhao, Chia-Chen Liu, Takahisa Kanekiyo, Austin J Yang, Alison M Goate, David M Holtzman, Guojun B. ApoE Cascade Hypothesis in the pathogenesis of Alzheimer's disease and related dementias. Neuron. 2022-03-17. PMID:35298921. |
apoe cascade hypothesis in the pathogenesis of alzheimer's disease and related dementias. |
2022-03-17 |
2023-08-13 |
Not clear |
| Willa D Brenowitz, Nathaniel M Robbins, Elsa S Strotmeyer, Kristine Yaff. Associations of Lower Extremity Peripheral Nerve Impairment and Risk of Dementia in Black and White Older Adults. Neurology. 2022-03-10. PMID:35264428. |
we evaluated whether lower extremity peripheral nerve impairments were associated with higher incidence of dementia and whether associations differed by comorbidity subgroups (diabetes, low vitamin b12, and apoe ε4 allele carriers). |
2022-03-10 |
2023-08-13 |
Not clear |
| So Young Yoo, Alexander Han, Soowon Park, Jun-Young Le. Incidence and Cognitive Decline of Alzheimer's Disease and Other Dementia by Apolipoprotein ε4 Allele Presence: A Community-Based Cohort Study in Korean Elderly. Psychiatry investigation. 2022-03-02. PMID:35232006. |
this study aimed to investigate the role of apolipoprotein e (apoe) ε4 allele to the incidence of dementia and cognitive decline in a cohort of a korean community. |
2022-03-02 |
2023-08-13 |
Not clear |
| Tau Ming Lie. Subjective cognitive decline, APOE e4 allele, and the risk of neurocognitive disorders: Age- and sex-stratified cohort study. The Australian and New Zealand journal of psychiatry. 2022-03-01. PMID:35229693. |
subjective cognitive decline and apoe e4 allele (apoe4) are known predictors of mild cognitive impairment and dementia (mild cognitive impairment/dementia), with recent evidence showing interaction between subjective cognitive decline and apoe4 in amplifying the risk of mild cognitive impairment/dementia. |
2022-03-01 |
2023-08-13 |
Not clear |
| Hao Ma, Tao Zhou, Xiang Li, Yoriko Heianza, Lu Q. Use of fish oil supplements is differently related to incidence of all-cause and vascular dementia among people with the distinct APOE ε4 dosage. Clinical nutrition (Edinburgh, Scotland). vol 41. issue 3. 2022-02-16. PMID:35172255. |
use of fish oil supplements is differently related to incidence of all-cause and vascular dementia among people with the distinct apoe ε4 dosage. |
2022-02-16 |
2023-08-13 |
Not clear |
| Hao Ma, Tao Zhou, Xiang Li, Yoriko Heianza, Lu Q. Use of fish oil supplements is differently related to incidence of all-cause and vascular dementia among people with the distinct APOE ε4 dosage. Clinical nutrition (Edinburgh, Scotland). vol 41. issue 3. 2022-02-16. PMID:35172255. |
we aimed to prospectively assess the relations between use of fish oil supplements and risks of all-cause and disease-specific dementia according to the apolipoprotein e (apoe) ε4 dosage. |
2022-02-16 |
2023-08-13 |
Not clear |
| Valéria Sutti Nunes, Guilherme da Silva Ferreira, Eder Carlos Rocha Quintã. Cholesterol metabolism in aging simultaneously altered in liver and nervous system. Aging. vol 14. issue undefined. 2022-02-07. PMID:35130181. |
apolipoprotein e (apoe) is important in transporting cholesterol from astrocytes to neurons in the etiology of sporadic alzheimer's disease, an aging-related dementia. |
2022-02-07 |
2023-08-13 |
mouse |
| Xiaohui Liu, Pan Zhuang, Yin Li, Fei Wu, Xuzhi Wan, Yu Zhang, Jingjing Jia. Association of fish oil supplementation with risk of incident dementia: A prospective study of 215,083 older adults. Clinical nutrition (Edinburgh, Scotland). vol 41. issue 3. 2022-02-06. PMID:35124466. |
we aim to assess the relationship between fish oil supplementation and incident dementia risk among older adults with different apolipoprotein e (apoe) genotypes in a large population-based cohort. |
2022-02-06 |
2023-08-13 |
Not clear |
| Alexander Thomson, Jun Liu, Bruno Bonnechère, Najaf Amin, Cornelia M Van Duij. Disentangling the relationship between apolipoprotein E, cardiovascular disease, COVID-19, dementia and mortality. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 3. 2022-02-03. PMID:35109390. |
the apolipoprotein e gene (apoe) is the most important single determinant of dementia risk but has also been implicated in life span. |
2022-02-03 |
2023-08-13 |
Not clear |
| Rui Liu, Shi Tang, Yongxiang Wang, Yi Dong, Tingting Hou, Yifei Ren, Lin Cong, Keke Liu, Yu Qin, Shireen Sindi, Yifeng Du, Chengxuan Qi. Self-reported sleep characteristics associated with dementia among rural-dwelling Chinese older adults: a population-based study. BMC neurology. vol 22. issue 1. 2022-01-04. PMID:34979998. |
sleep characteristics associated with dementia are poorly defined and whether their associations vary by demographics and apoe genotype among older adults are unclear. |
2022-01-04 |
2023-08-13 |
Not clear |
| Liling Dong, Chenhui Mao, Caiyan Liu, Jie Li, Xinying Huang, Jie Wang, Dan Lei, Shanshan Chu, Longze Sha, Qi Xu, Bin Peng, Liying Cui, Jing Ga. Association Between Common Variants of APOE, ABCA7, A2M, BACE1, and Cerebrospinal Fluid Biomarkers in Alzheimer's Disease: Data from the PUMCH Dementia Cohort. Journal of Alzheimer's disease : JAD. 2021-12-27. PMID:34958020. |
association between common variants of apoe, abca7, a2m, bace1, and cerebrospinal fluid biomarkers in alzheimer's disease: data from the pumch dementia cohort. |
2021-12-27 |
2023-08-13 |
Not clear |
| Jozsef Gal, Yuriko Katsumata, Haining Zhu, Sukanya Srinivasan, Jing Chen, Lance Allen Johnson, Wang-Xia Wang, Lesley Renee Golden, Donna M Wilcock, Gregory A Jicha, Matthew D Cykowski, Peter Tobias Nelso. Apolipoprotein E proteinopathy is a major dementia-associated pathologic biomarker in individuals with or without the APOE epsilon 4 allele. The American journal of pathology. 2021-12-26. PMID:34954207. |
among all detected peptides, apolipoprotein e (apoe) stood out: even more than the expected tau, app/aβ, and α-synuclein peptides, apoe peptides were strongly enriched in dementia cases - including from individuals lacking the apoe ε4 genotype. |
2021-12-26 |
2023-08-13 |
human |
| Liling Dong, Jie Li, Caiyan Liu, Chenhui Mao, Jie Wang, Dan Lei, Xinying Huang, Shanshan Chu, Bo Hou, Feng Feng, Longze Sha, Qi Xu, Jing Ga. Effects of ApoE genotype on clinical phenotypes in early-onset and late-onset Alzheimer's disease in China: Data from the PUMCH dementia cohort. Brain and behavior. vol 11. issue 11. 2021-12-09. PMID:34555265. |
effects of apoe genotype on clinical phenotypes in early-onset and late-onset alzheimer's disease in china: data from the pumch dementia cohort. |
2021-12-09 |
2023-08-13 |
Not clear |
| Soo Hyun Cho, Sookyoung Woo, Changsoo Kim, Hee Jin Kim, Hyemin Jang, Byeong C Kim, Si Eun Kim, Seung Joo Kim, Jun Pyo Kim, Young Hee Jung, Samuel Lockhart, Rik Ossenkoppele, Susan Landau, Duk L Na, Michael Weiner, Seonwoo Kim, Sang Won Se. Disease progression modelling from preclinical Alzheimer's disease (AD) to AD dementia. Scientific reports. vol 11. issue 1. 2021-11-15. PMID:33603015. |
our results suggest that disease progression modelling from preclinical ad to ad dementia may help clinicians to estimate where patients are in the disease course and provide information on variation in the disease course by sex and apoe ε4 status. |
2021-11-15 |
2023-08-13 |
Not clear |
| Katrine L Rasmussen, Anne Tybjaerg-Hansen, Børge G Nordestgaard, Ruth Frikke-Schmid. APOE and dementia - resequencing and genotyping in 105,597 individuals. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 16. issue 12. 2021-11-11. PMID:32808727. |
apoe and dementia - resequencing and genotyping in 105,597 individuals. |
2021-11-11 |
2023-08-13 |
Not clear |
| Katrine L Rasmussen, Anne Tybjaerg-Hansen, Børge G Nordestgaard, Ruth Frikke-Schmid. APOE and dementia - resequencing and genotyping in 105,597 individuals. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 16. issue 12. 2021-11-11. PMID:32808727. |
because low plasma levels of apoe associate with risk of dementia, genetic variants altering apoe levels in general may also associate with dementia. |
2021-11-11 |
2023-08-13 |
Not clear |
| Giulia Grande, Alessandra Marengoni, Davide L Vetrano, Albert Roso-Llorach, Debora Rizzuto, Alberto Zucchelli, Chengxuan Qiu, Laura Fratiglioni, Amaia Calderón-Larrañag. Multimorbidity burden and dementia risk in older adults: The role of inflammation and genetics. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17. issue 5. 2021-11-10. PMID:33403740. |
we investigate dementia risk in older adults with different disease patterns and explore the role of inflammation and apolipoprotein e (apoe) genotype. |
2021-11-10 |
2023-08-13 |
Not clear |