| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ida Juul Rasmussen, Anne Tybjærg-Hansen, Katrine Laura Rasmussen, Børge G Nordestgaard, Ruth Frikke-Schmid. Blood-brain barrier transcytosis genes, risk of dementia and stroke: a prospective cohort study of 74,754 individuals. European journal of epidemiology. vol 34. issue 6. 2019-09-27. PMID:30830563. |
genetic variants in picalm, bin1, cd2ap, and rin3 are associated with increased risk of alzheimer's disease, all dementia, and suggested vascular dementia independent of the strong apoe ε4 allele. |
2019-09-27 |
2023-08-13 |
Not clear |
| Lucas Kraft, Louise C Serpell, John R Atac. A Biophysical Approach to the Identification of Novel ApoE Chemical Probes. Biomolecules. vol 9. issue 2. 2019-08-30. PMID:30700058. |
alzheimer's disease (ad) is the most common type of dementia and, after age, the greatest risk factor for developing ad is the allelic variation of apolipoprotein e (apoe), with homozygote carriers of the apoe4 allele having an up to 12-fold greater risk of developing ad than noncarriers. |
2019-08-30 |
2023-08-13 |
Not clear |
| Keith A Hawkins, Nazli Emadi, Godfrey D Pearlson, Beth Taylor, Sabin Khadka, Diana King, Karen Blan. The effect of age and smoking on the hippocampus and memory in late middle age. Hippocampus. vol 28. issue 11. 2019-08-26. PMID:30070068. |
we studied associations between smoking history, age, apoe e4 genotype, vascular risk factors, hippocampal volume, and cognition in 67 middle-aged subjects (mean age = 56 years) who were offspring of parents with dementia. |
2019-08-26 |
2023-08-13 |
human |
| Fabricio Ferreira de Oliveira, Sandro Soares de Almeida, Elizabeth Suchi Chen, Marilia Cardoso Smith, Maria da Graça Naffah-Mazzacoratti, Paulo Henrique Ferreira Bertolucc. Lifetime Risk Factors for Functional and Cognitive Outcomes in Patients with Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 65. issue 4. 2019-08-26. PMID:30149448. |
consecutive outpatients with late-onset ad were assessed for apoe haplotypes and the following potential baseline predictors: gender, schooling, age at dementia onset, lifetime urban living and sanitary conditions, occupational complexity, cognitive and physical activities, cerebrovascular risk factors (obesity, lifetime alcohol use and smoking, length of arterial hypertension, diabetes mellitus, and a dyslipidemic profile), use of a pacemaker, creatinine clearance, body mass index, waist circumference, head traumas with unconsciousness, treated systemic bacterial infections, amount of surgical procedures under general anesthesia, and family history of ad. |
2019-08-26 |
2023-08-13 |
human |
| Kumar B Rajan, Lisa L Barnes, Robert S Wilson, Jennifer Weuve, Elizabeth A McAninch, Denis A Evan. Blood pressure and risk of incident Alzheimer's disease dementia by antihypertensive medications and APOE ε4 allele. Annals of neurology. vol 83. issue 5. 2019-08-13. PMID:29637601. |
blood pressure and risk of incident alzheimer's disease dementia by antihypertensive medications and apoe ε4 allele. |
2019-08-13 |
2023-08-13 |
Not clear |
| Christopher C Stewart, Patricia A Boyle, Bryan D James, Lei Yu, S Duke Han, David A Bennet. Associations of APOE ε4 With Health and Financial Literacy Among Community-Based Older Adults Without Dementia. The journals of gerontology. Series B, Psychological sciences and social sciences. vol 73. issue 5. 2019-08-09. PMID:27174891. |
associations of apoe ε4 with health and financial literacy among community-based older adults without dementia. |
2019-08-09 |
2023-08-13 |
Not clear |
| Christopher C Stewart, Patricia A Boyle, Bryan D James, Lei Yu, S Duke Han, David A Bennet. Associations of APOE ε4 With Health and Financial Literacy Among Community-Based Older Adults Without Dementia. The journals of gerontology. Series B, Psychological sciences and social sciences. vol 73. issue 5. 2019-08-09. PMID:27174891. |
we therefore examined associations of health and financial literacy with the apoe ε4 allele, the chief genetic risk factor for alzheimer's disease, among older adults without dementia. |
2019-08-09 |
2023-08-13 |
Not clear |
| Jessica Tulloch, Lesley Leong, Sunny Chen, C Dirk Keene, Steven P Millard, Andrew Shutes-David, Oscar L Lopez, Julia Kofler, Jeffrey A Kaye, Randy Woltjer, Peter T Nelson, Janna H Neltner, Gregory A Jicha, Douglas Galasko, Eliezer Masliah, James B Leverenz, Chang-En Yu, Debby Tsuan. APOE DNA methylation is altered in Lewy body dementia. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 14. issue 7. 2019-08-09. PMID:29544979. |
apoe dna methylation is altered in lewy body dementia. |
2019-08-09 |
2023-08-13 |
Not clear |
| Jessica Tulloch, Lesley Leong, Sunny Chen, C Dirk Keene, Steven P Millard, Andrew Shutes-David, Oscar L Lopez, Julia Kofler, Jeffrey A Kaye, Randy Woltjer, Peter T Nelson, Janna H Neltner, Gregory A Jicha, Douglas Galasko, Eliezer Masliah, James B Leverenz, Chang-En Yu, Debby Tsuan. APOE DNA methylation is altered in Lewy body dementia. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 14. issue 7. 2019-08-09. PMID:29544979. |
inheritance of the ε4 allele of apolipoprotein e (apoe) increases a person's risk of developing both alzheimer's disease (ad) and lewy body dementia (lbd), yet the underlying mechanisms behind this risk are incompletely understood. |
2019-08-09 |
2023-08-13 |
Not clear |
| Tobias Skillbäck, Ronald Lautner, Niklas Mattsson, Jonathan M Schott, Ingmar Skoog, Katarina Nägga, Lena Kilander, Anders Wimo, Bengt Winblad, Maria Eriksdotter, Kaj Blennow, Henrik Zetterber. Apolipoprotein E genotypes and longevity across dementia disorders. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 14. issue 7. 2019-08-09. PMID:29548722. |
the ε4 allele of the apolipoprotein e (apoe) gene is a prominent risk factor for alzheimer's disease (ad), but its implication in other dementias is less well studied. |
2019-08-09 |
2023-08-13 |
Not clear |
| Yuemiao Yin, Zhao Wan. ApoE and Neurodegenerative Diseases in Aging. Advances in experimental medicine and biology. vol 1086. 2019-07-23. PMID:30232753. |
age and apolipoprotein e (apoe) are the mightiest risk factors for dementia and cardiovascular diseases, but the underlying mechanisms remain unclear. |
2019-07-23 |
2023-08-13 |
human |
| Stephen P Salloway, Reisa Sperling, Nick C Fox, Marwan N Sabbagh, Lawrence S Honig, Anton P Porsteinsson, Hany Rofael, Nzeera Ketter, Daniel Wang, Enchi Liu, Stephen Carr, Ronald S Black, H Robert Brashea. Long-Term Follow Up of Patients with Mild-to-Moderate Alzheimer's Disease Treated with Bapineuzumab in a Phase III, Open-Label, Extension Study. Journal of Alzheimer's disease : JAD. vol 64. issue 3. 2019-07-15. PMID:29914022. |
a 3-year extension of two phase iii parent studies of intravenous (iv) bapineuzumab in patients with mild-to-moderate alzheimer's disease dementia (apolipoprotein (apoe) ɛ4 carriers and noncarriers) is summarized. |
2019-07-15 |
2023-08-13 |
Not clear |
| Michelle K Lupton, Sarah E Medland, Scott D Gordon, Tabatha Goncalves, Stuart MacGregor, David A Mackey, Terri L Young, David L Duffy, Peter M Visscher, Naomi R Wray, Dale R Nyholt, Lisa Bain, Manuel A Ferreira, Anjali K Henders, Leanne Wallace, Grant W Montgomery, Margaret J Wright, Nicholas G Marti. Accuracy of Inferred APOE Genotypes for a Range of Genotyping Arrays and Imputation Reference Panels. Journal of Alzheimer's disease : JAD. vol 64. issue 1. 2019-06-26. PMID:29865051. |
cohort studies investigating aging and dementia require apoe genotyping. |
2019-06-26 |
2023-08-13 |
Not clear |
| Madeleine L Werhane, Kelsey R Thomas, Emily C Edmonds, Katherine J Bangen, My Tran, Alexandra L Clark, Daniel A Nation, Paul E Gilbert, Mark W Bondi, Lisa Delano-Woo. Differential Effect of APOE ɛ4 Status and Elevated Pulse Pressure on Functional Decline in Cognitively Normal Older Adults. Journal of Alzheimer's disease : JAD. vol 62. issue 4. 2019-05-28. PMID:29562507. |
the apoe ɛ4 allele and increased vascular risk have both been independently linked to cognitive impairment and dementia. |
2019-05-28 |
2023-08-13 |
human |
| Salvatore Mazzeo, Sonia Padiglioni, Silvia Bagnoli, Laura Bracco, Benedetta Nacmias, Sandro Sorbi, Valentina Bess. The dual role of cognitive reserve in subjective cognitive decline and mild cognitive impairment: a 7-year follow-up study. Journal of neurology. vol 266. issue 2. 2019-05-28. PMID:30604054. |
on the contrary, high cr resulted as a risk factor for progression from mci to ad dementia only in apoe ε4 carriers. |
2019-05-28 |
2023-08-13 |
human |
| Salvatore Mazzeo, Sonia Padiglioni, Silvia Bagnoli, Laura Bracco, Benedetta Nacmias, Sandro Sorbi, Valentina Bess. The dual role of cognitive reserve in subjective cognitive decline and mild cognitive impairment: a 7-year follow-up study. Journal of neurology. vol 266. issue 2. 2019-05-28. PMID:30604054. |
in line with the previous researches, we found an interaction between cr and apoe in progression from mci to ad dementia. |
2019-05-28 |
2023-08-13 |
human |
| Anna Pierzchlińska, Monika Białecka, Mateusz Kurzawski, Jarosław Sławe. The impact of Apolipoprotein E alleles on cognitive performance in patients with Parkinson's disease. Neurologia i neurochirurgia polska. vol 52. issue 4. 2019-05-23. PMID:29776682. |
however, the impact of apoe genotypes on parkinson's disease dementia (pdd) is still inconclusive. |
2019-05-23 |
2023-08-13 |
human |
| Katrine L Rasmussen, Anne Tybjærg-Hansen, Børge G Nordestgaard, Ruth Frikke-Schmid. Plasma apolipoprotein E levels and risk of dementia: A Mendelian randomization study of 106,562 individuals. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 14. issue 1. 2019-05-17. PMID:28774656. |
in recent prospective studies, low plasma levels of apolipoprotein e (apoe) are associated with high risk of dementia. |
2019-05-17 |
2023-08-13 |
Not clear |
| Laure Rouch, Philippe Cestac, Brigitte Sallerin, Sandrine Andrieu, Henri Bailly, Maëlle Beunardeau, Adrien Cohen, Delphine Dubail, Intza Hernandorena, Marie-Laure Seux, Jean-Sébastien Vidal, Olivier Hano. Pulse Wave Velocity Is Associated With Greater Risk of Dementia in Mild Cognitive Impairment Patients. Hypertension (Dallas, Tex. : 1979). vol 72. issue 5. 2019-05-13. PMID:30354804. |
higher pulse wave velocity was associated with greater risk of conversion to dementia (1-sd increase of pulse wave velocity: hazard ratio, 1.33; 95% ci, 1.04-1.71; p=0.02) independently of age, sex, educational level, systolic blood pressure, cardiovascular diseases, body mass index, calcium channel blockers intake, mini-mental state examination at baseline, and apoe ε4 status. |
2019-05-13 |
2023-08-13 |
human |
| Qian Yang, Kang Chen, Hanlin Zhang, Wanying Zhang, Changlin Gong, Qing Zhang, Pan Liu, Tianyi Sun, Yuanyuan Xu, Xiaojing Qian, Wenying Qiu, Chao M. Correlations Between Single Nucleotide Polymorphisms, Cognitive Dysfunction, and Postmortem Brain Pathology in Alzheimer's Disease Among Han Chinese. Neuroscience bulletin. vol 35. issue 2. 2019-04-29. PMID:30783964. |
apoe ε4 (or = 4.482, p = 0.004), the rs2305421 gg genotype (adjusted or = 4.397, p = 0.015), and the rs10498633 gt genotype (adjusted or = 2.375, p = 0.028) were associated with a higher score on the abc (aβ plaque score, braak nft stage, and cerad neuritic plaque score) dementia scale. |
2019-04-29 |
2023-08-13 |
human |