Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Christopher C Stewart, Patricia A Boyle, Bryan D James, Lei Yu, S Duke Han, David A Bennet. Associations of APOE ε4 With Health and Financial Literacy Among Community-Based Older Adults Without Dementia. The journals of gerontology. Series B, Psychological sciences and social sciences. vol 73. issue 5. 2019-08-09. PMID:27174891. |
we therefore examined associations of health and financial literacy with the apoe ε4 allele, the chief genetic risk factor for alzheimer's disease, among older adults without dementia. |
2019-08-09 |
2023-08-13 |
Not clear |
Jessica Tulloch, Lesley Leong, Sunny Chen, C Dirk Keene, Steven P Millard, Andrew Shutes-David, Oscar L Lopez, Julia Kofler, Jeffrey A Kaye, Randy Woltjer, Peter T Nelson, Janna H Neltner, Gregory A Jicha, Douglas Galasko, Eliezer Masliah, James B Leverenz, Chang-En Yu, Debby Tsuan. APOE DNA methylation is altered in Lewy body dementia. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 14. issue 7. 2019-08-09. PMID:29544979. |
apoe dna methylation is altered in lewy body dementia. |
2019-08-09 |
2023-08-13 |
Not clear |
Jessica Tulloch, Lesley Leong, Sunny Chen, C Dirk Keene, Steven P Millard, Andrew Shutes-David, Oscar L Lopez, Julia Kofler, Jeffrey A Kaye, Randy Woltjer, Peter T Nelson, Janna H Neltner, Gregory A Jicha, Douglas Galasko, Eliezer Masliah, James B Leverenz, Chang-En Yu, Debby Tsuan. APOE DNA methylation is altered in Lewy body dementia. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 14. issue 7. 2019-08-09. PMID:29544979. |
inheritance of the ε4 allele of apolipoprotein e (apoe) increases a person's risk of developing both alzheimer's disease (ad) and lewy body dementia (lbd), yet the underlying mechanisms behind this risk are incompletely understood. |
2019-08-09 |
2023-08-13 |
Not clear |
Tobias Skillbäck, Ronald Lautner, Niklas Mattsson, Jonathan M Schott, Ingmar Skoog, Katarina Nägga, Lena Kilander, Anders Wimo, Bengt Winblad, Maria Eriksdotter, Kaj Blennow, Henrik Zetterber. Apolipoprotein E genotypes and longevity across dementia disorders. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 14. issue 7. 2019-08-09. PMID:29548722. |
the ε4 allele of the apolipoprotein e (apoe) gene is a prominent risk factor for alzheimer's disease (ad), but its implication in other dementias is less well studied. |
2019-08-09 |
2023-08-13 |
Not clear |
Yuemiao Yin, Zhao Wan. ApoE and Neurodegenerative Diseases in Aging. Advances in experimental medicine and biology. vol 1086. 2019-07-23. PMID:30232753. |
age and apolipoprotein e (apoe) are the mightiest risk factors for dementia and cardiovascular diseases, but the underlying mechanisms remain unclear. |
2019-07-23 |
2023-08-13 |
human |
Stephen P Salloway, Reisa Sperling, Nick C Fox, Marwan N Sabbagh, Lawrence S Honig, Anton P Porsteinsson, Hany Rofael, Nzeera Ketter, Daniel Wang, Enchi Liu, Stephen Carr, Ronald S Black, H Robert Brashea. Long-Term Follow Up of Patients with Mild-to-Moderate Alzheimer's Disease Treated with Bapineuzumab in a Phase III, Open-Label, Extension Study. Journal of Alzheimer's disease : JAD. vol 64. issue 3. 2019-07-15. PMID:29914022. |
a 3-year extension of two phase iii parent studies of intravenous (iv) bapineuzumab in patients with mild-to-moderate alzheimer's disease dementia (apolipoprotein (apoe) ɛ4 carriers and noncarriers) is summarized. |
2019-07-15 |
2023-08-13 |
Not clear |
Michelle K Lupton, Sarah E Medland, Scott D Gordon, Tabatha Goncalves, Stuart MacGregor, David A Mackey, Terri L Young, David L Duffy, Peter M Visscher, Naomi R Wray, Dale R Nyholt, Lisa Bain, Manuel A Ferreira, Anjali K Henders, Leanne Wallace, Grant W Montgomery, Margaret J Wright, Nicholas G Marti. Accuracy of Inferred APOE Genotypes for a Range of Genotyping Arrays and Imputation Reference Panels. Journal of Alzheimer's disease : JAD. vol 64. issue 1. 2019-06-26. PMID:29865051. |
cohort studies investigating aging and dementia require apoe genotyping. |
2019-06-26 |
2023-08-13 |
Not clear |
Madeleine L Werhane, Kelsey R Thomas, Emily C Edmonds, Katherine J Bangen, My Tran, Alexandra L Clark, Daniel A Nation, Paul E Gilbert, Mark W Bondi, Lisa Delano-Woo. Differential Effect of APOE ɛ4 Status and Elevated Pulse Pressure on Functional Decline in Cognitively Normal Older Adults. Journal of Alzheimer's disease : JAD. vol 62. issue 4. 2019-05-28. PMID:29562507. |
the apoe ɛ4 allele and increased vascular risk have both been independently linked to cognitive impairment and dementia. |
2019-05-28 |
2023-08-13 |
human |
Salvatore Mazzeo, Sonia Padiglioni, Silvia Bagnoli, Laura Bracco, Benedetta Nacmias, Sandro Sorbi, Valentina Bess. The dual role of cognitive reserve in subjective cognitive decline and mild cognitive impairment: a 7-year follow-up study. Journal of neurology. vol 266. issue 2. 2019-05-28. PMID:30604054. |
on the contrary, high cr resulted as a risk factor for progression from mci to ad dementia only in apoe ε4 carriers. |
2019-05-28 |
2023-08-13 |
human |
Salvatore Mazzeo, Sonia Padiglioni, Silvia Bagnoli, Laura Bracco, Benedetta Nacmias, Sandro Sorbi, Valentina Bess. The dual role of cognitive reserve in subjective cognitive decline and mild cognitive impairment: a 7-year follow-up study. Journal of neurology. vol 266. issue 2. 2019-05-28. PMID:30604054. |
in line with the previous researches, we found an interaction between cr and apoe in progression from mci to ad dementia. |
2019-05-28 |
2023-08-13 |
human |
Anna Pierzchlińska, Monika Białecka, Mateusz Kurzawski, Jarosław Sławe. The impact of Apolipoprotein E alleles on cognitive performance in patients with Parkinson's disease. Neurologia i neurochirurgia polska. vol 52. issue 4. 2019-05-23. PMID:29776682. |
however, the impact of apoe genotypes on parkinson's disease dementia (pdd) is still inconclusive. |
2019-05-23 |
2023-08-13 |
human |
Katrine L Rasmussen, Anne Tybjærg-Hansen, Børge G Nordestgaard, Ruth Frikke-Schmid. Plasma apolipoprotein E levels and risk of dementia: A Mendelian randomization study of 106,562 individuals. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 14. issue 1. 2019-05-17. PMID:28774656. |
in recent prospective studies, low plasma levels of apolipoprotein e (apoe) are associated with high risk of dementia. |
2019-05-17 |
2023-08-13 |
Not clear |
Laure Rouch, Philippe Cestac, Brigitte Sallerin, Sandrine Andrieu, Henri Bailly, Maëlle Beunardeau, Adrien Cohen, Delphine Dubail, Intza Hernandorena, Marie-Laure Seux, Jean-Sébastien Vidal, Olivier Hano. Pulse Wave Velocity Is Associated With Greater Risk of Dementia in Mild Cognitive Impairment Patients. Hypertension (Dallas, Tex. : 1979). vol 72. issue 5. 2019-05-13. PMID:30354804. |
higher pulse wave velocity was associated with greater risk of conversion to dementia (1-sd increase of pulse wave velocity: hazard ratio, 1.33; 95% ci, 1.04-1.71; p=0.02) independently of age, sex, educational level, systolic blood pressure, cardiovascular diseases, body mass index, calcium channel blockers intake, mini-mental state examination at baseline, and apoe ε4 status. |
2019-05-13 |
2023-08-13 |
human |
Qian Yang, Kang Chen, Hanlin Zhang, Wanying Zhang, Changlin Gong, Qing Zhang, Pan Liu, Tianyi Sun, Yuanyuan Xu, Xiaojing Qian, Wenying Qiu, Chao M. Correlations Between Single Nucleotide Polymorphisms, Cognitive Dysfunction, and Postmortem Brain Pathology in Alzheimer's Disease Among Han Chinese. Neuroscience bulletin. vol 35. issue 2. 2019-04-29. PMID:30783964. |
apoe ε4 (or = 4.482, p = 0.004), the rs2305421 gg genotype (adjusted or = 4.397, p = 0.015), and the rs10498633 gt genotype (adjusted or = 2.375, p = 0.028) were associated with a higher score on the abc (aβ plaque score, braak nft stage, and cerad neuritic plaque score) dementia scale. |
2019-04-29 |
2023-08-13 |
human |
Małgorzata T Piskunowicz, Katarzyna Linkowska, Szymon Gołota, Tomasz Grzybowski, Kornelia Kędziora-Kornatowska, Alina Borkowsk. The Association of Apolipoprotein E Gene Polymorphism With Cognitive Performance in Nondemented Polish Adults Aged 55 to 75. International journal of aging & human development. vol 87. issue 2. 2019-04-18. PMID:28844148. |
the ε4 allele of the apolipoprotein e (apoe) gene is known as a risk factor for dementia. |
2019-04-18 |
2023-08-13 |
human |
Małgorzata T Piskunowicz, Katarzyna Linkowska, Szymon Gołota, Tomasz Grzybowski, Kornelia Kędziora-Kornatowska, Alina Borkowsk. The Association of Apolipoprotein E Gene Polymorphism With Cognitive Performance in Nondemented Polish Adults Aged 55 to 75. International journal of aging & human development. vol 87. issue 2. 2019-04-18. PMID:28844148. |
in this study, the relationship between apoe status and cognitive performance across various cognitive domains in adults aged 55 to 75 years ( n = 74) without dementia was investigated. |
2019-04-18 |
2023-08-13 |
human |
Małgorzata T Piskunowicz, Katarzyna Linkowska, Szymon Gołota, Tomasz Grzybowski, Kornelia Kędziora-Kornatowska, Alina Borkowsk. The Association of Apolipoprotein E Gene Polymorphism With Cognitive Performance in Nondemented Polish Adults Aged 55 to 75. International journal of aging & human development. vol 87. issue 2. 2019-04-18. PMID:28844148. |
the findings support the relation between the apoe ε polymorphism and visual memory, short-term auditory memory, visuospatial attention, and executive functions in an aging sample without dementia. |
2019-04-18 |
2023-08-13 |
human |
Seonjoo Lee, Xingtao Zhou, Yizhe Gao, Badri Vardarajan, Dolly Reyes-Dumeyer, Kumar B Rajan, Robert S Wilson, Denis A Evans, Lilah M Besser, Walter A Kukull, David A Bennett, Adam M Brickman, Nicole Schupf, Richard Mayeux, Sandra Barra. Episodic memory performance in a multi-ethnic longitudinal study of 13,037 elderly. PloS one. vol 13. issue 11. 2019-04-15. PMID:30462667. |
episodic memory was investigated in 13,037 ethnically diverse elderly (ages 72 to 85 years) with two to 15 years of follow-up, and with known dementia status, age, sex, education, and apoe genotypes. |
2019-04-15 |
2023-08-13 |
human |
Seonjoo Lee, Xingtao Zhou, Yizhe Gao, Badri Vardarajan, Dolly Reyes-Dumeyer, Kumar B Rajan, Robert S Wilson, Denis A Evans, Lilah M Besser, Walter A Kukull, David A Bennett, Adam M Brickman, Nicole Schupf, Richard Mayeux, Sandra Barra. Episodic memory performance in a multi-ethnic longitudinal study of 13,037 elderly. PloS one. vol 13. issue 11. 2019-04-15. PMID:30462667. |
compared to those with stable trajectory, individuals characterized as decliners were more likely to have non-white ethnic background, fewer years of education, a higher frequency of ε4 allele at apoe gene and five times more likely to develop dementia. |
2019-04-15 |
2023-08-13 |
human |
Sven J van der Lee, Frank J Wolters, M Kamran Ikram, Albert Hofman, M Arfan Ikram, Najaf Amin, Cornelia M van Duij. The effect of APOE and other common genetic variants on the onset of Alzheimer's disease and dementia: a community-based cohort study. The Lancet. Neurology. vol 17. issue 5. 2019-03-15. PMID:29555425. |
the effect of apoe and other common genetic variants on the onset of alzheimer's disease and dementia: a community-based cohort study. |
2019-03-15 |
2023-08-13 |
Not clear |