| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Małgorzata T Piskunowicz, Katarzyna Linkowska, Szymon Gołota, Tomasz Grzybowski, Kornelia Kędziora-Kornatowska, Alina Borkowsk. The Association of Apolipoprotein E Gene Polymorphism With Cognitive Performance in Nondemented Polish Adults Aged 55 to 75. International journal of aging & human development. vol 87. issue 2. 2019-04-18. PMID:28844148. |
the ε4 allele of the apolipoprotein e (apoe) gene is known as a risk factor for dementia. |
2019-04-18 |
2023-08-13 |
human |
| Małgorzata T Piskunowicz, Katarzyna Linkowska, Szymon Gołota, Tomasz Grzybowski, Kornelia Kędziora-Kornatowska, Alina Borkowsk. The Association of Apolipoprotein E Gene Polymorphism With Cognitive Performance in Nondemented Polish Adults Aged 55 to 75. International journal of aging & human development. vol 87. issue 2. 2019-04-18. PMID:28844148. |
in this study, the relationship between apoe status and cognitive performance across various cognitive domains in adults aged 55 to 75 years ( n = 74) without dementia was investigated. |
2019-04-18 |
2023-08-13 |
human |
| Małgorzata T Piskunowicz, Katarzyna Linkowska, Szymon Gołota, Tomasz Grzybowski, Kornelia Kędziora-Kornatowska, Alina Borkowsk. The Association of Apolipoprotein E Gene Polymorphism With Cognitive Performance in Nondemented Polish Adults Aged 55 to 75. International journal of aging & human development. vol 87. issue 2. 2019-04-18. PMID:28844148. |
the findings support the relation between the apoe ε polymorphism and visual memory, short-term auditory memory, visuospatial attention, and executive functions in an aging sample without dementia. |
2019-04-18 |
2023-08-13 |
human |
| Seonjoo Lee, Xingtao Zhou, Yizhe Gao, Badri Vardarajan, Dolly Reyes-Dumeyer, Kumar B Rajan, Robert S Wilson, Denis A Evans, Lilah M Besser, Walter A Kukull, David A Bennett, Adam M Brickman, Nicole Schupf, Richard Mayeux, Sandra Barra. Episodic memory performance in a multi-ethnic longitudinal study of 13,037 elderly. PloS one. vol 13. issue 11. 2019-04-15. PMID:30462667. |
episodic memory was investigated in 13,037 ethnically diverse elderly (ages 72 to 85 years) with two to 15 years of follow-up, and with known dementia status, age, sex, education, and apoe genotypes. |
2019-04-15 |
2023-08-13 |
human |
| Seonjoo Lee, Xingtao Zhou, Yizhe Gao, Badri Vardarajan, Dolly Reyes-Dumeyer, Kumar B Rajan, Robert S Wilson, Denis A Evans, Lilah M Besser, Walter A Kukull, David A Bennett, Adam M Brickman, Nicole Schupf, Richard Mayeux, Sandra Barra. Episodic memory performance in a multi-ethnic longitudinal study of 13,037 elderly. PloS one. vol 13. issue 11. 2019-04-15. PMID:30462667. |
compared to those with stable trajectory, individuals characterized as decliners were more likely to have non-white ethnic background, fewer years of education, a higher frequency of ε4 allele at apoe gene and five times more likely to develop dementia. |
2019-04-15 |
2023-08-13 |
human |
| Sven J van der Lee, Frank J Wolters, M Kamran Ikram, Albert Hofman, M Arfan Ikram, Najaf Amin, Cornelia M van Duij. The effect of APOE and other common genetic variants on the onset of Alzheimer's disease and dementia: a community-based cohort study. The Lancet. Neurology. vol 17. issue 5. 2019-03-15. PMID:29555425. |
the effect of apoe and other common genetic variants on the onset of alzheimer's disease and dementia: a community-based cohort study. |
2019-03-15 |
2023-08-13 |
Not clear |
| Sven J van der Lee, Frank J Wolters, M Kamran Ikram, Albert Hofman, M Arfan Ikram, Najaf Amin, Cornelia M van Duij. The effect of APOE and other common genetic variants on the onset of Alzheimer's disease and dementia: a community-based cohort study. The Lancet. Neurology. vol 17. issue 5. 2019-03-15. PMID:29555425. |
we assessed the effects of these variants and apoe on cumulative risk and age at onset of alzheimer's disease and all-cause dementia. |
2019-03-15 |
2023-08-13 |
Not clear |
| Shanshan Wang, Jie Zhang, Tengwei Pa. APOE ε4 is associated with higher levels of CSF SNAP-25 in prodromal Alzheimer's disease. Neuroscience letters. vol 685. 2019-03-07. PMID:30144541. |
levels of csf snap-25 were compared between apoe ε4 carriers and noncarriers in 55 participants with normal cognition, 75 patients with mild cognitive impairment (mci), and 16 patients with mild ad dementia. |
2019-03-07 |
2023-08-13 |
human |
| Sookjaroen Tangwongchai, Thitiporn Supasitthumrong, Solaphat Hemrunroj, Chavit Tunvirachaisakul, Phenphichcha Chuchuen, Natnicha Houngngam, Thiti Snabboon, Ittipol Tawankanjanachot, Yuthachai Likitchareon, Kamman Phanthumchindad, Michael Mae. In Thai Nationals, the ApoE4 Allele Affects Multiple Domains of Neuropsychological, Biobehavioral, and Social Functioning Thereby Contributing to Alzheimer's Disorder, while the ApoE3 Allele Protects Against Neuropsychiatric Symptoms and Psychosocial Deficits. Molecular neurobiology. vol 55. issue 8. 2019-02-26. PMID:29307083. |
the aim of this study was to examine the associations between apoe alleles (e2, e3, e4) and genotypes and neuropsychological tests, behavioral functions, and dementia symptoms as assessed using consortium to establish a registry for alzheimer's disease (cerad). |
2019-02-26 |
2023-08-13 |
human |
| Petra Pasanen, Liisa Myllykangas, Minna Pöyhönen, Anna Kiviharju, Maija Siitonen, John Hardy, Jose Bras, Anders Paetau, Pentti J Tienari, Rita Guerreiro, Auli Verkkoniemi-Ahol. Genetics of dementia in a Finnish cohort. European journal of human genetics : EJHG. vol 26. issue 6. 2019-02-21. PMID:29476165. |
our aim was to clarify the genetic background of dementia in this cohort by analysing both known dementia-associated genes (apoe, app, c9orf72, grn, psen1 and psen2) and searching for rare or novel segregating variants with exome sequencing. |
2019-02-21 |
2023-08-13 |
human |
| María Belén Ruiz-Roso, Víctor Echeverry-Alzate, Baltasar Ruiz-Roso, José Carlos Quintela, Sandra Ballesteros, Vicente Lahera, Natalia de Las Heras, José Antonio López-Moreno, Beatriz Martín-Fernánde. Low Phytanic Acid-Concentrated DHA Prevents Cognitive Deficit and Regulates Alzheimer Disease Mediators in an ApoE Nutrients. vol 11. issue 1. 2019-02-12. PMID:30577526. |
low phytanic acid-concentrated dha prevents cognitive deficit and regulates alzheimer disease mediators in an apoe alzheimer's disease (ad) is the main cause of dementia and cognitive impairment. |
2019-02-12 |
2023-08-13 |
Not clear |
| Marco Túlio Gualberto Cintra, Rafaela Teixeira Ávila, Thayana Oliveira Soares, Luciana Cristina Matos Cunha, Katia Daniela Silveira, Edgar Nunes de Moraes, Kaique Roger Simas, Renato Bragança Fernandes, Denise Utsch Gonçalves, Nilton Alves de Rezende, Maria Aparecida Camargos Bicalh. Increased N200 and P300 latencies in cognitively impaired elderly carrying ApoE ε-4 allele. International journal of geriatric psychiatry. vol 33. issue 2. 2019-01-25. PMID:28833437. |
to compare the results of neuropsychological tests, evoked potentials n200 and p300 and polymorphisms of apoe and bdnf rs6265 between patients with normal cognition and those with mild cognitive impairment (mci) and alzheimer's dementia (ad). |
2019-01-25 |
2023-08-13 |
Not clear |
| Francisca S Rodriguez, Matthias L Schroeter, Katrin Arélin, A Veronica Witte, Ronny Baber, Ralph Burkhardt, Christoph Engel, Markus Löffler, Joachim Thiery, Arno Villringer, Tobias Luck, Steffi G Riedel-Helle. APOE e4-genotype and lifestyle interaction on cognitive performance: Results of the LIFE-Adult-study. Health psychology : official journal of the Division of Health Psychology, American Psychological Association. vol 37. issue 2. 2018-12-12. PMID:29215900. |
previous studies have shown that the e4-allele of the apoe gene is associated with a higher risk of developing dementia. |
2018-12-12 |
2023-08-13 |
Not clear |
| Francisca S Rodriguez, Matthias L Schroeter, Katrin Arélin, A Veronica Witte, Ronny Baber, Ralph Burkhardt, Christoph Engel, Markus Löffler, Joachim Thiery, Arno Villringer, Tobias Luck, Steffi G Riedel-Helle. APOE e4-genotype and lifestyle interaction on cognitive performance: Results of the LIFE-Adult-study. Health psychology : official journal of the Division of Health Psychology, American Psychological Association. vol 37. issue 2. 2018-12-12. PMID:29215900. |
our study investigated whether well-known associations between lifestyle factors and cognitive functioning may be stronger in individuals who carry the dementia risk variant of the apoe gene and whether this association is amplified with older age. |
2018-12-12 |
2023-08-13 |
Not clear |
| Kathleen Bokenberger, Arvid Sjölander, Anna K Dahl Aslan, Ida K Karlsson, Torbjörn Åkerstedt, Nancy L Pederse. Shift work and risk of incident dementia: a study of two population-based cohorts. European journal of epidemiology. vol 33. issue 10. 2018-11-26. PMID:30076495. |
among apoe ε4 carriers, individuals exposed to ≥ 20 years of shift work and night work had increased dementia risk compared to day workers. |
2018-11-26 |
2023-08-13 |
human |
| Lauren Massimo, Elizabeth Munoz, Nikki Hill, Jacqueline Mogle, Paula Mulhall, Corey T McMillan, Linda Clare, David Vandenbergh, Donna Fick, Ann Kolanowsk. Genetic and environmental factors associated with delirium severity in older adults with dementia. International journal of geriatric psychiatry. vol 32. issue 5. 2018-08-17. PMID:27122004. |
to determine (1) whether delirium severity was associated with apolipoprotein e (apoe) genotype status and occupational complexity, a measure of cognitive reserve, in individuals with delirium superimposed on dementia; and (2) whether decline in delirium severity was associated with these same factors over a post-acute care (pac) stay. |
2018-08-17 |
2023-08-13 |
Not clear |
| Weihong Zhang, Linlin Xin, Ying L. Integrative Analysis to Identify Common Genetic Markers of Metabolic Syndrome, Dementia, and Diabetes. Medical science monitor : international medical journal of experimental and clinical research. vol 23. 2018-08-06. PMID:29229897. |
the meta-regression analysis showed modest association of apoe with dementia and metabolic complications. |
2018-08-06 |
2023-08-13 |
Not clear |
| Reut Shnerb Ganor, Dror Harats, Ginette Schiby, Kinneret Rosenblatt, Irit Lubitz, Aviv Shaish, Ophira Salomo. Elderly apolipoprotein E‑/‑ mice with advanced atherosclerotic lesions in the aorta do not develop Alzheimer's disease-like pathologies. Molecular medicine reports. vol 17. issue 2. 2018-07-18. PMID:29207114. |
the mechanism by which apoe ko protects against brain pathology should be further studied as it may prove helpful for future treatment of senile dementia. |
2018-07-18 |
2023-08-13 |
mouse |
| Veronica Tisato, Giovanni Zuliani, Marco Vigliano, Giovanna Longo, Eugenia Franchini, Paola Secchiero, Giorgio Zauli, Elvezia Maria Paraboschi, Ajay Vikram Singh, Maria Luisa Serino, Beatrice Ortolani, Amedeo Zurlo, Cristina Bosi, Antonio Greco, Davide Seripa, Rosanna Asselta, Donato Gemmat. Gene-gene interactions among coding genes of iron-homeostasis proteins and APOE-alleles in cognitive impairment diseases. PloS one. vol 13. issue 3. 2018-07-13. PMID:29518107. |
in this light, we explored the role of common single nucleotide polymorphisms (snps) in the main iron homeostasis genes and in the main lipoprotein transporter gene (apoe) in a cohort of 765 patients with dementia of different origin: alzheimer's disease (ad) n = 276; vascular dementia (vad), n = 255; mild cognitive impairment (mci), n = 234; and in normal controls (n = 1086). |
2018-07-13 |
2023-08-13 |
Not clear |
| Marcus O W Grimm, Daniel M Michaelson, Tobias Hartman. Omega-3 fatty acids, lipids, and apoE lipidation in Alzheimer's disease: a rationale for multi-nutrient dementia prevention. Journal of lipid research. vol 58. issue 11. 2018-06-21. PMID:28528321. |
omega-3 fatty acids, lipids, and apoe lipidation in alzheimer's disease: a rationale for multi-nutrient dementia prevention. |
2018-06-21 |
2023-08-13 |
Not clear |