| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pei-Hsuan Weng, Jen-Hau Chen, Ta-Fu Chen, Yu Sun, Li-Li Wen, Ping-Keung Yip, Yi-Min Chu, Yen-Ching Che. CHRNA7 Polymorphisms and Dementia Risk: Interactions with Apolipoprotein ε4 and Cigarette Smoking. Scientific reports. vol 6. 2018-05-22. PMID:27249957. |
no studies explored the gene-gene, gene-environment interactions between chrna7 polymorphism, apolipoprotein e (apoe) ε4 status and smoking on dementia risk. |
2018-05-22 |
2023-08-13 |
human |
| Yen Ying Lim, Robert Williamson, Simon M Laws, Victor L Villemagne, Pierrick Bourgeat, Christopher Fowler, Stephanie Rainey-Smith, Olivier Salvado, Ralph N Martins, Christopher C Rowe, Colin L Masters, Paul Maruf. Effect of APOE Genotype on Amyloid Deposition, Brain Volume, and Memory in Cognitively Normal Older Individuals. Journal of Alzheimer's disease : JAD. vol 58. issue 4. 2018-05-22. PMID:28550258. |
the association between the apolipoprotein e (apoe) ɛ4 allele and high risk of developing alzheimer's disease (ad) dementia before the age of 80 has been recognized for over 30 years. |
2018-05-22 |
2023-08-13 |
Not clear |
| Enrica Cavedo, Simone Lista, Katrine Rojkova, Patrizia A Chiesa, Marion Houot, Katharina Brueggen, Janusch Blautzik, Arun L W Bokde, Bruno Dubois, Frederik Barkhof, Petra J W Pouwels, Stefan Teipel, Harald Hampe. Disrupted white matter structural networks in healthy older adult APOE ε4 carriers - An international multicenter DTI study. Neuroscience. vol 357. 2018-05-22. PMID:28596117. |
we examined the impact of apoe ε4 on wm microstructure in elderly individuals from the multicenter european dti study on dementia. |
2018-05-22 |
2023-08-13 |
human |
| Diana J Moreno, Sebastián Pino, Ángela Ríos, Francisco Lopera, Henry Ostos, Marc Via, Gabriel Bedoy. Genetic Ancestry and Susceptibility to Late-Onset Alzheimer Disease (LOAD) in the Admixed Colombian Population. Alzheimer disease and associated disorders. vol 31. issue 3. 2018-05-01. PMID:28369008. |
differences in the prevalence of dementia among populations and in the effect of apolipoprotein e (apoe) on the emergence of alzheimer disease (ad), which is the main type of dementia, have been reported. |
2018-05-01 |
2023-08-13 |
Not clear |
| Alessandro Biffi, Abbas Rattani, Christopher D Anderson, Alison M Ayres, Edip M Gurol, Steven M Greenberg, Jonathan Rosand, Anand Viswanatha. Delayed seizures after intracerebral haemorrhage. Brain : a journal of neurology. vol 139. issue Pt 10. 2018-04-10. PMID:27497491. |
factors associated with delayed seizures included cortical involvement on index haemorrhage (hazard ratio 1.63, p = 0.036), pre-haemorrhage dementia (hazard ratio 1.36, p = 0.044), history of multiple prior lobar haemorrhages (hazard ratio 2.50, p = 0.038), exclusively lobar microbleeds (hazard ratio 2.22, p = 0.008) and presence of ≥ 1 apoe ε4 copies (hazard ratio 1.95, p = 0.020). |
2018-04-10 |
2023-08-13 |
Not clear |
| Becca R Levy, Martin D Slade, Robert H Pietrzak, Luigi Ferrucc. Positive age beliefs protect against dementia even among elders with high-risk gene. PloS one. vol 13. issue 2. 2018-03-19. PMID:29414991. |
one of the strongest risk factors for dementia is the ε4 variant of the apoe gene. |
2018-03-19 |
2023-08-13 |
human |
| Becca R Levy, Martin D Slade, Robert H Pietrzak, Luigi Ferrucc. Positive age beliefs protect against dementia even among elders with high-risk gene. PloS one. vol 13. issue 2. 2018-03-19. PMID:29414991. |
the current study examined for the first time whether positive age beliefs that are acquired from the culture may reduce the risk of developing dementia among older individuals, including those who are apoe ε4 carriers. |
2018-03-19 |
2023-08-13 |
human |
| Becca R Levy, Martin D Slade, Robert H Pietrzak, Luigi Ferrucc. Positive age beliefs protect against dementia even among elders with high-risk gene. PloS one. vol 13. issue 2. 2018-03-19. PMID:29414991. |
among those with apoe ε4, those with positive age beliefs were 49.8% less likely to develop dementia than those with negative age beliefs. |
2018-03-19 |
2023-08-13 |
human |
| Diego Iacono, Inga Volkmann, Inger Nennesmo, Nancy L Pedersen, Laura Fratiglioni, Boo Johansson, David Karlsson, Bengt Winblad, Margaret Gat. Same Ages, Same Genes: Same Brains, Same Pathologies?: Dementia Timings, Co-Occurring Brain Pathologies, ApoE Genotypes in Identical and Fraternal Age-matched Twins at Autopsy. Alzheimer disease and associated disorders. vol 30. issue 2. 2018-03-05. PMID:26492328. |
: dementia timings, co-occurring brain pathologies, apoe genotypes in identical and fraternal age-matched twins at autopsy. |
2018-03-05 |
2023-08-13 |
Not clear |
| Simone Hollands, Yen Ying Lim, Simon M Laws, Victor L Villemagne, Robert H Pietrzak, Karra Harrington, Tenielle Porter, Peter Snyder, David Ames, Christopher Fowler, Stephanie R Rainey-Smith, Ralph N Martins, Olivier Salvado, Joanne Robertson, Christopher C Rowe, Colin L Masters, Paul Maruf. APOEɛ4 Genotype, Amyloid, and Clinical Disease Progression in Cognitively Normal Older Adults. Journal of Alzheimer's disease : JAD. vol 57. issue 2. 2018-02-26. PMID:28234254. |
in cognitively normal (cn) older adults, carriage of the apolipoprotein e (apoe) ɛ4 allele is associated with increased risk for dementia of the alzheimer type (ad-dementia). |
2018-02-26 |
2023-08-13 |
Not clear |
| Luís F J R Miranda, Karina B Gomes, Pedro A L Tito, Josianne N Silveira, Gerson A Pianetti, Ricardo M D Byrro, Patrícia R H Peles, Fernando H Pereira, Thiago R Santos, Arthur G Assini, Valéria V Ribeiro, Edgar N Moraes, Paulo Caramell. Clinical Response to Donepezil in Mild and Moderate Dementia: Relationship to Drug Plasma Concentration and CYP2D6 and APOE Genetic Polymorphisms. Journal of Alzheimer's disease : JAD. vol 55. issue 2. 2018-02-22. PMID:27716659. |
clinical response to donepezil in mild and moderate dementia: relationship to drug plasma concentration and cyp2d6 and apoe genetic polymorphisms. |
2018-02-22 |
2023-08-13 |
Not clear |
| Luís F J R Miranda, Karina B Gomes, Pedro A L Tito, Josianne N Silveira, Gerson A Pianetti, Ricardo M D Byrro, Patrícia R H Peles, Fernando H Pereira, Thiago R Santos, Arthur G Assini, Valéria V Ribeiro, Edgar N Moraes, Paulo Caramell. Clinical Response to Donepezil in Mild and Moderate Dementia: Relationship to Drug Plasma Concentration and CYP2D6 and APOE Genetic Polymorphisms. Journal of Alzheimer's disease : JAD. vol 55. issue 2. 2018-02-22. PMID:27716659. |
the clinical response to donepezil in patients with mild and moderate dementia was investigated in relation to the drug plasma concentration and apoe and cyp2d6 polymorphisms. |
2018-02-22 |
2023-08-13 |
Not clear |
| Barbara Fenesi, Hanna Fang, Ana Kovacevic, Mark Oremus, Parminder Raina, Jennifer J Heis. Physical Exercise Moderates the Relationship of Apolipoprotein E (APOE) Genotype and Dementia Risk: A Population-Based Study. Journal of Alzheimer's disease : JAD. vol 56. issue 1. 2018-02-21. PMID:27911292. |
physical exercise moderates the relationship of apolipoprotein e (apoe) genotype and dementia risk: a population-based study. |
2018-02-21 |
2023-08-13 |
Not clear |
| Barbara Fenesi, Hanna Fang, Ana Kovacevic, Mark Oremus, Parminder Raina, Jennifer J Heis. Physical Exercise Moderates the Relationship of Apolipoprotein E (APOE) Genotype and Dementia Risk: A Population-Based Study. Journal of Alzheimer's disease : JAD. vol 56. issue 1. 2018-02-21. PMID:27911292. |
we assessed the interactive relationship of apolipoprotein e (apoe) genotype and physical exercise on dementia risk over a 5-year period in 1,646 older adults from the canadian study of health and aging who were dementia-free at baseline. |
2018-02-21 |
2023-08-13 |
Not clear |
| Barbara Fenesi, Hanna Fang, Ana Kovacevic, Mark Oremus, Parminder Raina, Jennifer J Heis. Physical Exercise Moderates the Relationship of Apolipoprotein E (APOE) Genotype and Dementia Risk: A Population-Based Study. Journal of Alzheimer's disease : JAD. vol 56. issue 1. 2018-02-21. PMID:27911292. |
specifically, for apoe ɛ4 non-carriers, the odds of developing dementia were higher in non-exercisers than exercisers (or = 1.98, 95% ci = 1.44, 2.71, p < 0.001), whereas, for apoe ɛ4 carriers, the odds of developing dementia were not significantly different between non-exercisers and exercisers (or = 0.71, 95% ci = 0.46, 1.31, p = 0.34). |
2018-02-21 |
2023-08-13 |
Not clear |
| Melike Kahya, Eric Vidoni, Jeffrey M Burns, Ashley N Thompson, Kayla Meyer, Catherine F Siengsuko. The Relationship Between Apolipoprotein ε4 Carrier Status and Sleep Characteristics in Cognitively Normal Older Adults. Journal of geriatric psychiatry and neurology. vol 30. issue 5. 2018-02-14. PMID:28747136. |
data from n = 36 (apoe ε4 carriers [n = 9], noncarriers [n = 27]) cognitively normal older adults (clinical dementia rating [cdr] scale = 0) without self-reported sleep apnea were used for these analyses. |
2018-02-14 |
2023-08-13 |
human |
| David Mengel, Judith Dams, Jannis Ziemek, Julian Becker, Monika Balzer-Geldsetzer, Rüdiger Hilker, Simon Baudrexel, Elke Kalbe, Nele Schmidt, Karsten Witt, Inga Liepelt-Scarfone, Susanne Gräber, Annette Petrelli, Petra Neuser, Claudia Schulte, Katharina Linse, Alexander Storch, Hans-Ulrich Wittchen, Oliver Riedel, Brit Mollenhauer, Jens Ebentheuer, Claudia Trenkwalder, Thomas Klockgether, Annika Spottke, Ullrich Wüllner, Jörg B Schulz, Kathrin Reetz, Ines Ann Heber, Alfredo Ramirez, Richard Dode. Apolipoprotein E ε4 does not affect cognitive performance in patients with Parkinson's disease. Parkinsonism & related disorders. vol 29. 2018-02-05. PMID:27321987. |
the apolipoprotein e (apoe) allele ε4 is a known risk factor for alzheimer's disease and has also been suggested to be a risk factor for dementia in pd and even a predictor of impairment in certain cognitive domains. |
2018-02-05 |
2023-08-13 |
Not clear |
| Katherine J Bangen, Jayandra J Himali, Alexa S Beiser, Daniel A Nation, David J Libon, Caroline S Fox, Sudha Seshadri, Philip A Wolf, Ann C McKee, Rhoda Au, Lisa Delano-Woo. Interaction Between Midlife Blood Glucose and APOE Genotype Predicts Later Alzheimer's Disease Pathology. Journal of Alzheimer's disease : JAD. vol 53. issue 4. 2018-01-29. PMID:27392855. |
elevated blood glucose and the apolipoprotein (apoe) ɛ4 allele have both been associated with increased dementia risk; however, the neuropathological mechanisms underlying these associations remain unclear. |
2018-01-29 |
2023-08-13 |
human |
| Monika Mandecka, Magdalena Budziszewska, Anna Barczak, Beata Pepłońska, Małgorzata Chodakowska-Żebrowska, Anna Filipek-Gliszczyńska, Marta Nesteruk, Maria Styczyńska, Maria Barcikowska, Tomasz Gabryelewic. Association between Cerebrospinal Fluid Biomarkers for Alzheimer's Disease, APOE Genotypes and Auditory Verbal Learning Task in Subjective Cognitive Decline, Mild Cognitive Impairment, and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 54. issue 1. 2018-01-29. PMID:27472875. |
the aim of this study was to estimate the prevalence of ad csf biomarkers in those individuals with a subjective cognitive decline (scd), a mild cognitive impairment (mci), and alzheimer's dementia (ad-d), together with the relationships between the biomarkers, an apoe ɛ4 presence, and a verbal episodic memory performance. |
2018-01-29 |
2023-08-13 |
Not clear |
| P S Jairani, P M Aswathy, Srinivas Gopala, Joe Verghese, P S Mathuranat. Interaction with the MAPT H1H1 Genotype Increases Dementia Risk in APOE ε4 Carriers in a Population of Southern India. Dementia and geriatric cognitive disorders. vol 42. issue 5-6. 2018-01-23. PMID:27705964. |
interaction with the mapt h1h1 genotype increases dementia risk in apoe ε4 carriers in a population of southern india. |
2018-01-23 |
2023-08-13 |
Not clear |