| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Becca R Levy, Martin D Slade, Robert H Pietrzak, Luigi Ferrucc. Positive age beliefs protect against dementia even among elders with high-risk gene. PloS one. vol 13. issue 2. 2018-03-19. PMID:29414991. |
the current study examined for the first time whether positive age beliefs that are acquired from the culture may reduce the risk of developing dementia among older individuals, including those who are apoe ε4 carriers. |
2018-03-19 |
2023-08-13 |
human |
| Becca R Levy, Martin D Slade, Robert H Pietrzak, Luigi Ferrucc. Positive age beliefs protect against dementia even among elders with high-risk gene. PloS one. vol 13. issue 2. 2018-03-19. PMID:29414991. |
among those with apoe ε4, those with positive age beliefs were 49.8% less likely to develop dementia than those with negative age beliefs. |
2018-03-19 |
2023-08-13 |
human |
| Diego Iacono, Inga Volkmann, Inger Nennesmo, Nancy L Pedersen, Laura Fratiglioni, Boo Johansson, David Karlsson, Bengt Winblad, Margaret Gat. Same Ages, Same Genes: Same Brains, Same Pathologies?: Dementia Timings, Co-Occurring Brain Pathologies, ApoE Genotypes in Identical and Fraternal Age-matched Twins at Autopsy. Alzheimer disease and associated disorders. vol 30. issue 2. 2018-03-05. PMID:26492328. |
: dementia timings, co-occurring brain pathologies, apoe genotypes in identical and fraternal age-matched twins at autopsy. |
2018-03-05 |
2023-08-13 |
Not clear |
| Simone Hollands, Yen Ying Lim, Simon M Laws, Victor L Villemagne, Robert H Pietrzak, Karra Harrington, Tenielle Porter, Peter Snyder, David Ames, Christopher Fowler, Stephanie R Rainey-Smith, Ralph N Martins, Olivier Salvado, Joanne Robertson, Christopher C Rowe, Colin L Masters, Paul Maruf. APOEɛ4 Genotype, Amyloid, and Clinical Disease Progression in Cognitively Normal Older Adults. Journal of Alzheimer's disease : JAD. vol 57. issue 2. 2018-02-26. PMID:28234254. |
in cognitively normal (cn) older adults, carriage of the apolipoprotein e (apoe) ɛ4 allele is associated with increased risk for dementia of the alzheimer type (ad-dementia). |
2018-02-26 |
2023-08-13 |
Not clear |
| Luís F J R Miranda, Karina B Gomes, Pedro A L Tito, Josianne N Silveira, Gerson A Pianetti, Ricardo M D Byrro, Patrícia R H Peles, Fernando H Pereira, Thiago R Santos, Arthur G Assini, Valéria V Ribeiro, Edgar N Moraes, Paulo Caramell. Clinical Response to Donepezil in Mild and Moderate Dementia: Relationship to Drug Plasma Concentration and CYP2D6 and APOE Genetic Polymorphisms. Journal of Alzheimer's disease : JAD. vol 55. issue 2. 2018-02-22. PMID:27716659. |
clinical response to donepezil in mild and moderate dementia: relationship to drug plasma concentration and cyp2d6 and apoe genetic polymorphisms. |
2018-02-22 |
2023-08-13 |
Not clear |
| Luís F J R Miranda, Karina B Gomes, Pedro A L Tito, Josianne N Silveira, Gerson A Pianetti, Ricardo M D Byrro, Patrícia R H Peles, Fernando H Pereira, Thiago R Santos, Arthur G Assini, Valéria V Ribeiro, Edgar N Moraes, Paulo Caramell. Clinical Response to Donepezil in Mild and Moderate Dementia: Relationship to Drug Plasma Concentration and CYP2D6 and APOE Genetic Polymorphisms. Journal of Alzheimer's disease : JAD. vol 55. issue 2. 2018-02-22. PMID:27716659. |
the clinical response to donepezil in patients with mild and moderate dementia was investigated in relation to the drug plasma concentration and apoe and cyp2d6 polymorphisms. |
2018-02-22 |
2023-08-13 |
Not clear |
| Barbara Fenesi, Hanna Fang, Ana Kovacevic, Mark Oremus, Parminder Raina, Jennifer J Heis. Physical Exercise Moderates the Relationship of Apolipoprotein E (APOE) Genotype and Dementia Risk: A Population-Based Study. Journal of Alzheimer's disease : JAD. vol 56. issue 1. 2018-02-21. PMID:27911292. |
physical exercise moderates the relationship of apolipoprotein e (apoe) genotype and dementia risk: a population-based study. |
2018-02-21 |
2023-08-13 |
Not clear |
| Barbara Fenesi, Hanna Fang, Ana Kovacevic, Mark Oremus, Parminder Raina, Jennifer J Heis. Physical Exercise Moderates the Relationship of Apolipoprotein E (APOE) Genotype and Dementia Risk: A Population-Based Study. Journal of Alzheimer's disease : JAD. vol 56. issue 1. 2018-02-21. PMID:27911292. |
we assessed the interactive relationship of apolipoprotein e (apoe) genotype and physical exercise on dementia risk over a 5-year period in 1,646 older adults from the canadian study of health and aging who were dementia-free at baseline. |
2018-02-21 |
2023-08-13 |
Not clear |
| Barbara Fenesi, Hanna Fang, Ana Kovacevic, Mark Oremus, Parminder Raina, Jennifer J Heis. Physical Exercise Moderates the Relationship of Apolipoprotein E (APOE) Genotype and Dementia Risk: A Population-Based Study. Journal of Alzheimer's disease : JAD. vol 56. issue 1. 2018-02-21. PMID:27911292. |
specifically, for apoe ɛ4 non-carriers, the odds of developing dementia were higher in non-exercisers than exercisers (or = 1.98, 95% ci = 1.44, 2.71, p < 0.001), whereas, for apoe ɛ4 carriers, the odds of developing dementia were not significantly different between non-exercisers and exercisers (or = 0.71, 95% ci = 0.46, 1.31, p = 0.34). |
2018-02-21 |
2023-08-13 |
Not clear |
| Melike Kahya, Eric Vidoni, Jeffrey M Burns, Ashley N Thompson, Kayla Meyer, Catherine F Siengsuko. The Relationship Between Apolipoprotein ε4 Carrier Status and Sleep Characteristics in Cognitively Normal Older Adults. Journal of geriatric psychiatry and neurology. vol 30. issue 5. 2018-02-14. PMID:28747136. |
data from n = 36 (apoe ε4 carriers [n = 9], noncarriers [n = 27]) cognitively normal older adults (clinical dementia rating [cdr] scale = 0) without self-reported sleep apnea were used for these analyses. |
2018-02-14 |
2023-08-13 |
human |
| David Mengel, Judith Dams, Jannis Ziemek, Julian Becker, Monika Balzer-Geldsetzer, Rüdiger Hilker, Simon Baudrexel, Elke Kalbe, Nele Schmidt, Karsten Witt, Inga Liepelt-Scarfone, Susanne Gräber, Annette Petrelli, Petra Neuser, Claudia Schulte, Katharina Linse, Alexander Storch, Hans-Ulrich Wittchen, Oliver Riedel, Brit Mollenhauer, Jens Ebentheuer, Claudia Trenkwalder, Thomas Klockgether, Annika Spottke, Ullrich Wüllner, Jörg B Schulz, Kathrin Reetz, Ines Ann Heber, Alfredo Ramirez, Richard Dode. Apolipoprotein E ε4 does not affect cognitive performance in patients with Parkinson's disease. Parkinsonism & related disorders. vol 29. 2018-02-05. PMID:27321987. |
the apolipoprotein e (apoe) allele ε4 is a known risk factor for alzheimer's disease and has also been suggested to be a risk factor for dementia in pd and even a predictor of impairment in certain cognitive domains. |
2018-02-05 |
2023-08-13 |
Not clear |
| Katherine J Bangen, Jayandra J Himali, Alexa S Beiser, Daniel A Nation, David J Libon, Caroline S Fox, Sudha Seshadri, Philip A Wolf, Ann C McKee, Rhoda Au, Lisa Delano-Woo. Interaction Between Midlife Blood Glucose and APOE Genotype Predicts Later Alzheimer's Disease Pathology. Journal of Alzheimer's disease : JAD. vol 53. issue 4. 2018-01-29. PMID:27392855. |
elevated blood glucose and the apolipoprotein (apoe) ɛ4 allele have both been associated with increased dementia risk; however, the neuropathological mechanisms underlying these associations remain unclear. |
2018-01-29 |
2023-08-13 |
human |
| Monika Mandecka, Magdalena Budziszewska, Anna Barczak, Beata Pepłońska, Małgorzata Chodakowska-Żebrowska, Anna Filipek-Gliszczyńska, Marta Nesteruk, Maria Styczyńska, Maria Barcikowska, Tomasz Gabryelewic. Association between Cerebrospinal Fluid Biomarkers for Alzheimer's Disease, APOE Genotypes and Auditory Verbal Learning Task in Subjective Cognitive Decline, Mild Cognitive Impairment, and Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 54. issue 1. 2018-01-29. PMID:27472875. |
the aim of this study was to estimate the prevalence of ad csf biomarkers in those individuals with a subjective cognitive decline (scd), a mild cognitive impairment (mci), and alzheimer's dementia (ad-d), together with the relationships between the biomarkers, an apoe ɛ4 presence, and a verbal episodic memory performance. |
2018-01-29 |
2023-08-13 |
Not clear |
| P S Jairani, P M Aswathy, Srinivas Gopala, Joe Verghese, P S Mathuranat. Interaction with the MAPT H1H1 Genotype Increases Dementia Risk in APOE ε4 Carriers in a Population of Southern India. Dementia and geriatric cognitive disorders. vol 42. issue 5-6. 2018-01-23. PMID:27705964. |
interaction with the mapt h1h1 genotype increases dementia risk in apoe ε4 carriers in a population of southern india. |
2018-01-23 |
2023-08-13 |
Not clear |
| P S Jairani, P M Aswathy, Srinivas Gopala, Joe Verghese, P S Mathuranat. Interaction with the MAPT H1H1 Genotype Increases Dementia Risk in APOE ε4 Carriers in a Population of Southern India. Dementia and geriatric cognitive disorders. vol 42. issue 5-6. 2018-01-23. PMID:27705964. |
this study delineates the role of the interaction of apolipoprotein e (apoe) and mapt alleles in contributing to disease risks of dementia in a southern indian population. |
2018-01-23 |
2023-08-13 |
Not clear |
| Florence F Roussotte, Katherine L Narr, Gary W Small, Paul M Thompso. The C677T variant in MTHFR modulates associations between blood-based and cerebrospinal fluid biomarkers of neurodegeneration. Neuroreport. vol 27. issue 12. 2018-01-11. PMID:27380243. |
in t-homozygotes who do not carry the apoe-ε4 allele, the relationship between low plasma apoe levels and an increased risk of dementia is likely obscured by the presence of elevated plasma homocysteine. |
2018-01-11 |
2023-08-13 |
human |
| Giuseppe Nicoletti, David Neil Manners, Fabiana Novellino, Claudia Testa, Monica Gagliardi, Caterina Tonon, Raffaele Lodi, Aldo Quattron. Voxel-based morphometry to detect effect of APOE on brain gray matter changes in Parkinson's Disease. Psychiatry research. Neuroimaging. vol 254. 2017-12-07. PMID:27479921. |
the goal of the study was to determine association between apoe Ɛ4 and gray matter changes in pd patients, with or without dementia. |
2017-12-07 |
2023-08-13 |
Not clear |
| Giuseppe Nicoletti, David Neil Manners, Fabiana Novellino, Claudia Testa, Monica Gagliardi, Caterina Tonon, Raffaele Lodi, Aldo Quattron. Voxel-based morphometry to detect effect of APOE on brain gray matter changes in Parkinson's Disease. Psychiatry research. Neuroimaging. vol 254. 2017-12-07. PMID:27479921. |
twenty-five pd patients with the apoe Ɛ4 (13 with dementia), 24 without Ɛ4 (12 with dementia), and 26 controls were selected. |
2017-12-07 |
2023-08-13 |
Not clear |
| Giuseppe Nicoletti, David Neil Manners, Fabiana Novellino, Claudia Testa, Monica Gagliardi, Caterina Tonon, Raffaele Lodi, Aldo Quattron. Voxel-based morphometry to detect effect of APOE on brain gray matter changes in Parkinson's Disease. Psychiatry research. Neuroimaging. vol 254. 2017-12-07. PMID:27479921. |
our results provide no evidence of an association of the apoe Ɛ4 and gray matter degenerative changes in patients with pd, either with or without dementia. |
2017-12-07 |
2023-08-13 |
Not clear |
| Donald M Lyall, Joey Ward, Stuart J Ritchie, Gail Davies, Breda Cullen, Carlos Celis, Mark E S Bailey, Jana Anderson, Jon Evans, Daniel F Mckay, Andrew M Mcintosh, Naveed Sattar, Daniel J Smith, Ian J Deary, Jill P Pel. Alzheimer disease genetic risk factor APOE e4 and cognitive abilities in 111,739 UK Biobank participants. Age and ageing. vol 45. issue 4. 2017-11-20. PMID:27103599. |
the apolipoprotein (apoe) e4 locus is a genetic risk factor for dementia. |
2017-11-20 |
2023-08-13 |
human |