| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ida K Karlsson, Anna M Bennet, Alexander Ploner, Therese M-L Andersson, Chandra A Reynolds, Margaret Gatz, Nancy L Pederse. Apolipoprotein E ε4 genotype and the temporal relationship between depression and dementia. Neurobiology of aging. vol 36. issue 4. 2016-03-17. PMID:25670333. |
thus, depression with onset close in time to dementia onset is associated with disease irrespective of apoe genotype, whereas depression more distal to dementia onset is a risk factor only in ε4-carriers. |
2016-03-17 |
2023-08-13 |
Not clear |
| Chengzhi Mou, Tao Han, Min Wang, Meng Jiang, Bin Liu, Jia H. Correlation of polymorphism of APOE and LRP genes to cognitive impairment and behavioral and psychological symptoms of dementia in Alzheimer's disease and vascular dementia. International journal of clinical and experimental medicine. vol 8. issue 11. 2016-02-17. PMID:26885125. |
correlation of polymorphism of apoe and lrp genes to cognitive impairment and behavioral and psychological symptoms of dementia in alzheimer's disease and vascular dementia. |
2016-02-17 |
2023-08-13 |
Not clear |
| Chengzhi Mou, Tao Han, Min Wang, Meng Jiang, Bin Liu, Jia H. Correlation of polymorphism of APOE and LRP genes to cognitive impairment and behavioral and psychological symptoms of dementia in Alzheimer's disease and vascular dementia. International journal of clinical and experimental medicine. vol 8. issue 11. 2016-02-17. PMID:26885125. |
to discuss the correlation of polymorphism of apoe and lrp genes to cognitive impairment and behavioral and psychological symptoms of dementia (bpsd) in alzheimer's disease (ad) and vascular dementia (vd). |
2016-02-17 |
2023-08-13 |
Not clear |
| Swetha Vijayaraghavan, Walter Maetzler, Matthias Reimold, Christina Unger Lithner, Inga Liepelt-Scarfone, Daniela Berg, Taher Darreh-Shor. High apolipoprotein E in cerebrospinal fluid of patients with Lewy body disorders is associated with dementia. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 10. issue 5. 2016-02-04. PMID:23978325. |
indeed, similar to ad, patients with lbd displayed high csf apoe levels (greatest in patients with dementia with lbd), and this was linked to apoe ε4. |
2016-02-04 |
2023-08-12 |
Not clear |
| Swetha Vijayaraghavan, Walter Maetzler, Matthias Reimold, Christina Unger Lithner, Inga Liepelt-Scarfone, Daniela Berg, Taher Darreh-Shor. High apolipoprotein E in cerebrospinal fluid of patients with Lewy body disorders is associated with dementia. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 10. issue 5. 2016-02-04. PMID:23978325. |
accordingly, therapeutic strategies aimed at reducing apoe levels in the brain should be explored not only in ad but also in lbd, particularly when accompanied with dementia. |
2016-02-04 |
2023-08-12 |
Not clear |
| Bjørn Heine Strand, Tor Atle Rosness, Knut Engedal, Per Magnus, Astrid Liv Mina Bergem, Henrik Schirmer, Espen Bjertness, Gun Peggy Knudse. Interaction of Apolipoprotein E Genotypes, Lifestyle Factors and Future Risk of Dementia-Related Mortality: The Cohort of Norway (CONOR). Dementia and geriatric cognitive disorders. vol 40. issue 3-4. 2016-01-14. PMID:26088392. |
our aims were two-fold: firstly, to investigate the association and interaction between apolipoprotein e (apoe), lifestyle risk factors and dementia-related mortality and, secondly, to examine if using dementia-related mortality yielded comparable risk estimates for the apoe genotypes as reported in studies using a clinical dementia diagnosis as the end point. |
2016-01-14 |
2023-08-13 |
Not clear |
| Jennifer S Yokoyama, Allen K L Lee, Leonel T Takada, Edgar Busovaca, Luke W Bonham, Steven Z Chao, Marian Tse, Jing He, Christopher G Schwarz, Owen T Carmichael, Brandy R Matthews, Anna Karydas, Michael W Weiner, Giovanni Coppola, Charles S DeCarli, Bruce L Miller, Howard J Rose. Apolipoprotein ε4 is associated with lower brain volume in cognitively normal Chinese but not white older adults. PloS one. vol 10. issue 3. 2015-11-20. PMID:25738563. |
the allele frequency of apoe ε4 varies both across and within populations, and the size of the effect it confers for dementia risk may be affected by other factors. |
2015-11-20 |
2023-08-13 |
human |
| Jose Bras, Rita Guerreiro, Lee Darwent, Laura Parkkinen, Olaf Ansorge, Valentina Escott-Price, Dena G Hernandez, Michael A Nalls, Lorraine N Clark, Lawrence S Honig, Karen Marder, Wiesje M Van Der Flier, Afina Lemstra, Philip Scheltens, Ekaterina Rogaeva, Peter St George-Hyslop, Elisabet Londos, Henrik Zetterberg, Sara Ortega-Cubero, Pau Pastor, Tanis J Ferman, Neill R Graff-Radford, Owen A Ross, Imelda Barber, Anne Braae, Kristelle Brown, Kevin Morgan, Walter Maetzler, Daniela Berg, Claire Troakes, Safa Al-Sarraj, Tammaryn Lashley, Yaroslau Compta, Tamas Revesz, Andrew Lees, Nigel Cairns, Glenda M Halliday, David Mann, Stuart Pickering-Brown, Dennis W Dickson, Andrew Singleton, John Hard. Genetic analysis implicates APOE, SNCA and suggests lysosomal dysfunction in the etiology of dementia with Lewy bodies. Human molecular genetics. vol 23. issue 23. 2015-10-29. PMID:24973356. |
genetic analysis implicates apoe, snca and suggests lysosomal dysfunction in the etiology of dementia with lewy bodies. |
2015-10-29 |
2023-08-13 |
Not clear |
| Jeffrey Rollo, Stacey Knight, Heidi T May, Jeffrey L Anderson, Joseph B Muhlestein, T Jared Bunch, John Carlquis. Incidence of dementia in relation to genetic variants at PITX2, ZFHX3, and ApoE ε4 in atrial fibrillation patients. Pacing and clinical electrophysiology : PACE. vol 38. issue 2. 2015-10-22. PMID:25494715. |
incidence of dementia in relation to genetic variants at pitx2, zfhx3, and apoe ε4 in atrial fibrillation patients. |
2015-10-22 |
2023-08-13 |
Not clear |
| Jeffrey Rollo, Stacey Knight, Heidi T May, Jeffrey L Anderson, Joseph B Muhlestein, T Jared Bunch, John Carlquis. Incidence of dementia in relation to genetic variants at PITX2, ZFHX3, and ApoE ε4 in atrial fibrillation patients. Pacing and clinical electrophysiology : PACE. vol 38. issue 2. 2015-10-22. PMID:25494715. |
these markers may identify af patients at risk for dementia either directly or through a gene-gene interaction with the apoe ε4 variant, a known marker of dementia risk. |
2015-10-22 |
2023-08-13 |
Not clear |
| Zvinka Z Zlatar, Christina E Wierenga, Katherine J Bangen, Thomas T Liu, Amy J Ja. Increased hippocampal blood flow in sedentary older adults at genetic risk for Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 41. issue 3. 2015-09-18. PMID:24685629. |
results indicate that the relationship between sedentary time and cbf in the left hippocampus differs by apoe status, whereby apoe ε4 carriers show higher cbf as a function of longer sedentary time (b = 10.8, se = 3.17, β = 0.74, t = 3.41, p < 0.01) compared to noncarriers (b = 1.4, se = 2.7, β = 0.096, t = 0.51, p = 0.61), possibly suggesting a cbf regulatory response to compensate for metabolic alterations in dementia risk. |
2015-09-18 |
2023-08-12 |
Not clear |
| Ann M Kolanowski, Nikki L Hill, Esra Kurum, Donna M Fick, Andrea M Yevchak, Paula Mulhall, Linda Clare, Michael Valenzuel. Gender differences in factors associated with delirium severity in older adults with dementia. Archives of psychiatric nursing. vol 28. issue 3. 2015-09-18. PMID:24856271. |
the purpose of this descriptive correlational study was to explore potential gender differences in the relationship of dementia severity, age, apoe status, cognitive reserve and co-morbidity (two potentially modifiable factors), to delirium severity in older adults. |
2015-09-18 |
2023-08-13 |
human |
| Lisa L Barnes, David A Bennet. Dementia: Cognitive resilience in APOE*ε4 carriers—is race important? Nature reviews. Neurology. vol 11. issue 4. 2015-08-28. PMID:25799927. |
dementia: cognitive resilience in apoe*ε4 carriers—is race important? |
2015-08-28 |
2023-08-13 |
Not clear |
| Margaret Esiri, Steven Chance, Catharine Joachim, Donald Warden, Aidan Smallwood, Carolyn Sloan, Sharon Christie, Gordon Wilcock, A David Smit. Cerebral amyloid angiopathy, subcortical white matter disease and dementia: literature review and study in OPTIMA. Brain pathology (Zurich, Switzerland). vol 25. issue 1. 2015-08-12. PMID:25521177. |
these findings draw attention, as have many other studies, to the importance of apoe genotype as a major risk factor not only for dementia but also for damage to blood vessels in the aging brain. |
2015-08-12 |
2023-08-13 |
human |
| Keith A Josephs, Joseph R Duffy, Edythe A Strand, Mary M Machulda, Matthew L Senjem, Val J Lowe, Clifford R Jack, Jennifer L Whitwel. APOE ε4 influences β-amyloid deposition in primary progressive aphasia and speech apraxia. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 10. issue 6. 2015-07-30. PMID:24985533. |
apolipoprotein e ε4 (apoe ε4) is a risk factor for β-amyloid deposition in alzheimer's disease dementia. |
2015-07-30 |
2023-08-13 |
Not clear |
| N Iu Bachyns'ka, I F Rozheliuk, V O Kholyn, I M Pishel', Iu I Leono. [ApoE gene polymorphism as a predictor of therapeutic response to treatment acetylcholinesterase inhibitor for elderly patients with Alzheimer's and vascular dementia types]. Wiadomosci lekarskie (Warsaw, Poland : 1960). vol 67. issue 2 Pt 2. 2015-07-22. PMID:25796815. |
[apoe gene polymorphism as a predictor of therapeutic response to treatment acetylcholinesterase inhibitor for elderly patients with alzheimer's and vascular dementia types]. |
2015-07-22 |
2023-08-13 |
Not clear |
| N Iu Bachyns'ka, I F Rozheliuk, V O Kholyn, I M Pishel', Iu I Leono. [ApoE gene polymorphism as a predictor of therapeutic response to treatment acetylcholinesterase inhibitor for elderly patients with Alzheimer's and vascular dementia types]. Wiadomosci lekarskie (Warsaw, Poland : 1960). vol 67. issue 2 Pt 2. 2015-07-22. PMID:25796815. |
effectiveness of donepezil hydrochloride treatment for elderly patients with alzheimer's and vascular dementia types depending on the apoe genotype. |
2015-07-22 |
2023-08-13 |
Not clear |
| Wen-Zheng Chu, Li Gong, Ying-Qiu Xu, Guo-Hua Cai, Kuo-Chen Cho. Apolipoprotein E gene variants of Alzheimer's disease and vascular dementia patients in a community population of Nanking. Medicinal chemistry (Shariqah (United Arab Emirates)). vol 10. issue 8. 2015-06-19. PMID:24678786. |
to explore apolipoprotein e gene variants distribution among the patients of alzheimer's disease and vascular dementia for the elderly community population in nanking, the polymerase chain reaction and restriction fragment length polymorphism techniques were employed to analyze the gene frequency of apolipoprotein e (apoe) for 113 cases with alzheimer's disease (ad), 85 cases with vascular dementia (vad), 147 cases with questionable dementia (qd), and 396 dementia-free controls. |
2015-06-19 |
2023-08-12 |
Not clear |
| Anna Pink, Gorazd B Stokin, Mairead M Bartley, Rosebud O Roberts, Ondrej Sochor, Mary M Machulda, Janina Krell-Roesch, David S Knopman, Jazmin I Acosta, Teresa J Christianson, V Shane Pankratz, Michelle M Mielke, Ronald C Petersen, Yonas E Ged. Neuropsychiatric symptoms, APOE ε4, and the risk of incident dementia: a population-based study. Neurology. vol 84. issue 9. 2015-06-15. PMID:25653291. |
neuropsychiatric symptoms, apoe ε4, and the risk of incident dementia: a population-based study. |
2015-06-15 |
2023-08-13 |
human |
| Anna Pink, Gorazd B Stokin, Mairead M Bartley, Rosebud O Roberts, Ondrej Sochor, Mary M Machulda, Janina Krell-Roesch, David S Knopman, Jazmin I Acosta, Teresa J Christianson, V Shane Pankratz, Michelle M Mielke, Ronald C Petersen, Yonas E Ged. Neuropsychiatric symptoms, APOE ε4, and the risk of incident dementia: a population-based study. Neurology. vol 84. issue 9. 2015-06-15. PMID:25653291. |
to investigate the population-based interaction between a biological variable (apoe ε4), neuropsychiatric symptoms, and the risk of incident dementia among subjects with prevalent mild cognitive impairment (mci). |
2015-06-15 |
2023-08-13 |
human |