Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
M Chaudhry, S Hasnain, B E Snitz, X Wang, S Rosenthal, F Y Demirci, M I Kambo. Association of APOE polymorphisms and stressful life events with dementia in a Pakistani population. Neuroscience letters. vol 570. 2014-12-01. PMID:24746929. |
association of apoe polymorphisms and stressful life events with dementia in a pakistani population. |
2014-12-01 |
2023-08-13 |
human |
M Chaudhry, S Hasnain, B E Snitz, X Wang, S Rosenthal, F Y Demirci, M I Kambo. Association of APOE polymorphisms and stressful life events with dementia in a Pakistani population. Neuroscience letters. vol 570. 2014-12-01. PMID:24746929. |
alzheimer's disease (ad) is a major form of dementia and the apoe 4 allele is an established genetic risk factor for ad. |
2014-12-01 |
2023-08-13 |
human |
M Chaudhry, S Hasnain, B E Snitz, X Wang, S Rosenthal, F Y Demirci, M I Kambo. Association of APOE polymorphisms and stressful life events with dementia in a Pakistani population. Neuroscience letters. vol 570. 2014-12-01. PMID:24746929. |
the objective of this study was to examine the association of apoe 4 and stressful life events with dementia in a pakistani sample, which to our knowledge has not been reported previously. |
2014-12-01 |
2023-08-13 |
human |
M Chaudhry, S Hasnain, B E Snitz, X Wang, S Rosenthal, F Y Demirci, M I Kambo. Association of APOE polymorphisms and stressful life events with dementia in a Pakistani population. Neuroscience letters. vol 570. 2014-12-01. PMID:24746929. |
we also tested for an interaction between stressful life events and apoe 4 on dementia risk. |
2014-12-01 |
2023-08-13 |
human |
M Chaudhry, S Hasnain, B E Snitz, X Wang, S Rosenthal, F Y Demirci, M I Kambo. Association of APOE polymorphisms and stressful life events with dementia in a Pakistani population. Neuroscience letters. vol 570. 2014-12-01. PMID:24746929. |
apoe 4 and stressful life events were each independently and significantly associated with the risk of dementia (apoe 4: p=0.00697; stressful life events: p=5.29e-09). |
2014-12-01 |
2023-08-13 |
human |
M Chaudhry, S Hasnain, B E Snitz, X Wang, S Rosenthal, F Y Demirci, M I Kambo. Association of APOE polymorphisms and stressful life events with dementia in a Pakistani population. Neuroscience letters. vol 570. 2014-12-01. PMID:24746929. |
however, we did not find a significant interaction between apoe 4 carrier status and stressful life events on risk of dementia (p=0.677). |
2014-12-01 |
2023-08-13 |
human |
M Chaudhry, S Hasnain, B E Snitz, X Wang, S Rosenthal, F Y Demirci, M I Kambo. Association of APOE polymorphisms and stressful life events with dementia in a Pakistani population. Neuroscience letters. vol 570. 2014-12-01. PMID:24746929. |
although the sample size of this study was small, the established association of apoe 4 with dementia was confirmed the first time in a pakistani sample. |
2014-12-01 |
2023-08-13 |
human |
Isabel Hernández, Ana Mauleón, Maiteé Rosense-Roca, Montserrat Alegret, Georgina Vinyes, Anna Espinosa, Oscar Sotolongo-Grau, James T Becker, Sergi Valero, Lluís Tarraga, Oscar L López, Agustín Ruiz, Mercè Boad. Identification of misdiagnosed fronto-temporal dementia using APOE genotype and phenotype-genotype correlation analyses. Current Alzheimer research. vol 11. issue 2. 2014-11-24. PMID:24359501. |
identification of misdiagnosed fronto-temporal dementia using apoe genotype and phenotype-genotype correlation analyses. |
2014-11-24 |
2023-08-12 |
Not clear |
Philip J Batterham, David Bunce, Nicolas Cherbuin, Helen Christense. Apolipoprotein E ε4 and later-life decline in cognitive function and grip strength. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 21. issue 10. 2014-10-24. PMID:23567378. |
presence of the apolipoprotein e (apoe) ε4 allele is a risk factor for dementia, whereas the ε2 allele offers protection against dementia. |
2014-10-24 |
2023-08-12 |
Not clear |
Philip J Batterham, David Bunce, Nicolas Cherbuin, Helen Christense. Apolipoprotein E ε4 and later-life decline in cognitive function and grip strength. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 21. issue 10. 2014-10-24. PMID:23567378. |
this study examined whether apoe genotype was associated with either initial performance or change in performance on a range of cognitive and noncognitive tasks, after accounting for possible preclinical dementia. |
2014-10-24 |
2023-08-12 |
Not clear |
Sun-Ho Han, Jun Seok Kim, Youngju Lee, Heesun Choi, Jong-Won Kim, Duk Lyul Na, Eun Gyeong Yang, Myeong-Hee Yu, Daehee Hwang, Cheolju Lee, Inhee Mook-Jun. Both targeted mass spectrometry and flow sorting analysis methods detected the decreased serum apolipoprotein E level in Alzheimer's disease patients. Molecular & cellular proteomics : MCP. vol 13. issue 2. 2014-10-09. PMID:24319058. |
correlation study suggested that a decrease of the serum apoe level in ad is related to the mini-mental state exam score in both results from different experimental methods, but it failed to show consistent correlation with age, gender, or clinical dementia rating. |
2014-10-09 |
2023-08-12 |
Not clear |
Fabricio Ferreira de Oliveira, Paulo Henrique Ferreira Bertolucci, Elizabeth Suchi Chen, Marilia de Arruda Cardoso Smit. Pharmacological modulation of cognitive and behavioral symptoms in patients with dementia due to Alzheimer's disease. Journal of the neurological sciences. vol 336. issue 1-2. 2014-09-29. PMID:24189208. |
to evaluate correlations of pharmacological treatment with cognitive and behavioral symptoms in patients with dementia due to alzheimer's disease with low schooling, subjects were assessed for demographic features, neuropsychiatric symptoms, cognitive decline, functionality, caregiver burden, apoe haplotypes and pharmacological treatment. |
2014-09-29 |
2023-08-12 |
human |
Fabricio Ferreira de Oliveira, Paulo Henrique Ferreira Bertolucci, Elizabeth Suchi Chen, Marilia de Arruda Cardoso Smit. Pharmacological modulation of cognitive and behavioral symptoms in patients with dementia due to Alzheimer's disease. Journal of the neurological sciences. vol 336. issue 1-2. 2014-09-29. PMID:24189208. |
a trend was found for treatment with cholinesterase inhibitors and memantine to be associated with longer lengths of dementia for moderately impaired but not for severely impaired patients, regardless of apoe haplotypes, translating into a synergistic effect among such medications for slowing cognitive decline but not for prolonging survival. |
2014-09-29 |
2023-08-12 |
human |
Lei Yu, Patricia A Boyle, Sue Leurgans, Julie A Schneider, David A Bennet. Disentangling the effects of age and APOE on neuropathology and late life cognitive decline. Neurobiology of aging. vol 35. issue 4. 2014-09-29. PMID:24199961. |
age and apoe are the most robust risk factors for dementia and cognitive decline, but the underlying neurobiology remains unclear. |
2014-09-29 |
2023-08-12 |
human |
Sylvia Villeneuve, Diane Brisson, Natalie L Marchant, Daniel Gaude. The potential applications of Apolipoprotein E in personalized medicine. Frontiers in aging neuroscience. vol 6. 2014-07-29. PMID:25071563. |
empirical evidence suggests that apoe genotype informs pre-symptomatic risk for a wide variety of diseases, is valuable for the diagnosis of type iii dysbetalipoproteinemia, increases risk of dementia in neurodegenerative diseases, and is associated with a poor prognosis following acute brain damage. |
2014-07-29 |
2023-08-13 |
Not clear |
Daniel J Berlau, María M Corrada, John L Robinson, Felix Geser, Steven E Arnold, Virginia M-Y Lee, Claudia H Kawas, John Q Trojanowsk. Neocortical β-amyloid area is associated with dementia and APOE in the oldest-old. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 9. issue 6. 2014-06-20. PMID:23474043. |
neocortical β-amyloid area is associated with dementia and apoe in the oldest-old. |
2014-06-20 |
2023-08-12 |
Not clear |
Daniel J Berlau, María M Corrada, John L Robinson, Felix Geser, Steven E Arnold, Virginia M-Y Lee, Claudia H Kawas, John Q Trojanowsk. Neocortical β-amyloid area is associated with dementia and APOE in the oldest-old. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 9. issue 6. 2014-06-20. PMID:23474043. |
apolipoprotein e (apoe) ε2 carriers may be protected from dementia because of reduced levels of cortical β-amyloid. |
2014-06-20 |
2023-08-12 |
Not clear |
Daniel J Berlau, María M Corrada, John L Robinson, Felix Geser, Steven E Arnold, Virginia M-Y Lee, Claudia H Kawas, John Q Trojanowsk. Neocortical β-amyloid area is associated with dementia and APOE in the oldest-old. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 9. issue 6. 2014-06-20. PMID:23474043. |
we compared different measures of β-amyloid pathology across apoe genotypes in the oldest-old, and their relationship with dementia. |
2014-06-20 |
2023-08-12 |
Not clear |
Florence F Roussotte, Boris A Gutman, Sarah K Madsen, John B Colby, Paul M Thompso. Combined effects of Alzheimer risk variants in the CLU and ApoE genes on ventricular expansion patterns in the elderly. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 19. 2014-06-17. PMID:24806679. |
the rs11136000 major c allele-previously linked with reduced clu expression and with increased risk for dementia-predicted faster expansion, independently of dementia status or apoe genotype. |
2014-06-17 |
2023-08-13 |
human |
Michael J Lyons, Margo Genderson, Michael D Grant, Mark Logue, Tyler Zink, Ruth McKenzie, Carol E Franz, Matthew Panizzon, James B Lohr, Beth Jerskey, William S Kreme. Gene-environment interaction of ApoE genotype and combat exposure on PTSD. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 162B. issue 7. 2014-05-27. PMID:24132908. |
the €4 allele of the apolipoprotein e (apoe) gene is associated with dementia and unfavorable outcome following brain insult. |
2014-05-27 |
2023-08-12 |
human |