| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Li-Yuan Zhang, Lie-Song Chen, Rui Sun, Sheng-Jun Ji, Yan-Yan Ding, Jia Wu, Ye Tia. Effects of expression level of DNA repair-related genes involved in the NHEJ pathway on radiation-induced cognitive impairment. Journal of radiation research. vol 54. issue 2. 2013-12-05. PMID:23135157. |
impairments of hippocampal neurogenesis are thought to be a paramountly important mechanism underlying radiation-induced cognitive dysfunction. |
2013-12-05 |
2023-08-12 |
rat |
| Hsing-Yu Chen, Yin Miranda Yang, Ruolan Han, Mark Nobl. MEK1/2 inhibition suppresses tamoxifen toxicity on CNS glial progenitor cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 38. 2013-11-26. PMID:24048837. |
clinical studies indicate that exposure even to tamoxifen (tmx), a putatively benign antihormonal agent widely used in breast cancer treatment, causes cognitive dysfunction and changes in cns metabolism, hippocampal volume, and brain structure. |
2013-11-26 |
2023-08-12 |
mouse |
| Sahabudeen Sheik Mohideen, Sahoko Ichihara, Kaviarasan Subramanian, Zhenlie Huang, Hisao Naito, Junzoh Kitoh, Gaku Ichihar. Effects of exposure to 1-bromopropane on astrocytes and oligodendrocytes in rat brain. Journal of occupational health. vol 55. issue 1. 2013-09-30. PMID:23183024. |
human cases of 1-bromopropane (1-bp) toxicity showed ataxic gait and cognitive dysfunction, whereas rat studies showed pyknotic shrinkage in cerebellar purkinje cells and electrophysiological changes in the hippocampus. |
2013-09-30 |
2023-08-12 |
human |
| Paolo Calabresi, Anna Castrioto, Massimiliano Di Filippo, Barbara Piccon. New experimental and clinical links between the hippocampus and the dopaminergic system in Parkinson's disease. The Lancet. Neurology. vol 12. issue 8. 2013-09-19. PMID:23867199. |
clinical and experimental findings support the view that the hippocampus, a temporal lobe structure involved in physiological learning and memory, is also implicated in the cognitive dysfunction seen in some patients with parkinson's disease. |
2013-09-19 |
2023-08-12 |
Not clear |
| Nadja Schröder, Luciana Silva Figueiredo, Maria Noêmia Martins de Lim. Role of brain iron accumulation in cognitive dysfunction: evidence from animal models and human studies. Journal of Alzheimer's disease : JAD. vol 34. issue 4. 2013-09-12. PMID:23271321. |
remarkably, recent human studies using magnetic resonance image techniques have also shown a consistent correlation between cognitive dysfunction and iron deposition, mostly in the hippocampus, cortical areas, and basal ganglia. |
2013-09-12 |
2023-08-12 |
human |
| Mohammad Ahma. Protective effects of curcumin against lithium-pilocarpine induced status epilepticus, cognitive dysfunction and oxidative stress in young rats. Saudi journal of biological sciences. vol 20. issue 2. 2013-08-20. PMID:23961231. |
besides its anticonvulsant effect, cur significantly ameliorates se-induced cognitive dysfunction and oxidative damages in the hippocampus and striatum areas of the brain. |
2013-08-20 |
2023-08-12 |
rat |
| Akiko Sheala Shingo, Tomomichi Kanabayashi, Shozo Kito, Toshio Muras. Intracerebroventricular administration of an insulin analogue recovers STZ-induced cognitive decline in rats. Behavioural brain research. vol 241. 2013-07-01. PMID:23238038. |
we previously demonstrated that intracerebroventricular streptozotocin (stz-icv) injection induced cognitive dysfunction and led to decreased expression levels of phospho-cyclic amp responsive element binding protein (pcreb), akt, and insulin degrading enzyme (ide) and increased amyloid beta (ab) deposition in the hippocampus. |
2013-07-01 |
2023-08-12 |
rat |
| Francesca Inverardi, Maia Chikhladze, Andrea Donzelli, Ramona Frida Moroni, Maria Cristina Regondi, Paolo Pennacchio, Ileana Zucca, Irene Corradini, Daniela Braida, Mariaelvina Sala, Silvana Franceschetti, Carolina Frasson. Cytoarchitectural, behavioural and neurophysiological dysfunctions in the BCNU-treated rat model of cortical dysplasia. The European journal of neuroscience. vol 37. issue 1. 2013-06-11. PMID:23095101. |
the aim of this study was to investigate the behavioural, electrophysiological and anatomical profile of bcnu-treated rats in order to determine whether cortical and hippocampal lesions can directly lead to cognitive dysfunction. |
2013-06-11 |
2023-08-12 |
rat |
| Sukhwinder Kaur, Ritika Chhabra, Bimla Nehr. Ginkgo biloba extract attenuates hippocampal neuronal loss and cognitive dysfunction resulting from trimethyltin in mice. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 20. issue 2. 2013-06-10. PMID:23177260. |
ginkgo biloba extract attenuates hippocampal neuronal loss and cognitive dysfunction resulting from trimethyltin in mice. |
2013-06-10 |
2023-08-12 |
mouse |
| M Badruzzaman Khan, Mohd Moshahid Khan, Andleeb Khan, Md Ejaz Ahmed, Tauheed Ishrat, Rizwana Tabassum, Kumar Vaibhav, Ajmal Ahmad, Fakhrul Isla. Naringenin ameliorates Alzheimer's disease (AD)-type neurodegeneration with cognitive impairment (AD-TNDCI) caused by the intracerebroventricular-streptozotocin in rat model. Neurochemistry international. vol 61. issue 7. 2013-06-05. PMID:22898296. |
the present study was designed to investigate the pre-treatment effects of naringenin (nar), a polyphenolic compound on cognitive dysfunction, oxidative stress in the hippocampus, and hippocampal neuron injury in a rat model of ad-tndci. |
2013-06-05 |
2023-08-12 |
rat |
| Wei Gao, Hongyu Xu, Ming Liang, Jason H Huang, Xiaosheng H. Association between reduced expression of hippocampal glucocorticoid receptors and cognitive dysfunction in a rat model of traumatic brain injury due to lateral head acceleration. Neuroscience letters. vol 533. 2013-05-23. PMID:23200726. |
association between reduced expression of hippocampal glucocorticoid receptors and cognitive dysfunction in a rat model of traumatic brain injury due to lateral head acceleration. |
2013-05-23 |
2023-08-12 |
rat |
| Yan Zhou, Ze-qiang Qu, Yuan-shan Zeng, Yu-kun Lin, Yan Li, Peter Chung, Ricky Wong, Urban Häg. Neuroprotective effect of preadministration with Ganoderma lucidum spore on rat hippocampus. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie. vol 64. issue 7-8. 2013-03-26. PMID:21242065. |
the aim of this study was to investigate if preadministration with ganoderma lucidum spore (gls) could (1) alleviate oxidative stress and mitochondrial dysfunction in rat hippocampus of intracerebroventricular (icv) injection of streptozotocin (stz), (2) protect neurons from apoptosis, and (3) improve cognitive dysfunction. |
2013-03-26 |
2023-08-12 |
rat |
| Weibin Xie, Yan Yang, Xiaoping Gu, Yaguo Zheng, Yu-e Sun, Ying Liang, Jinhua Bo, Zhengliang M. Senegenin attenuates hepatic ischemia-reperfusion induced cognitive dysfunction by increasing hippocampal NR2B expression in rats. PloS one. vol 7. issue 9. 2013-03-06. PMID:23029109. |
senegenin attenuates hepatic ischemia-reperfusion induced cognitive dysfunction by increasing hippocampal nr2b expression in rats. |
2013-03-06 |
2023-08-12 |
rat |
| Valentina Emmanuele, Angels Garcia-Cazorla, Hua-Bin Huang, Jorida Coku, Beatriz Dorado, Etty P Cortes, Kristin Engelstad, Darryl C De Vivo, Salvatore Dimauro, Eduardo Bonilla, Kurenai Tanj. Decreased hippocampal expression of calbindin D28K and cognitive impairment in MELAS. Journal of the neurological sciences. vol 317. issue 1-2. 2013-02-11. PMID:22483853. |
in this study, we explored a possible link between cognitive dysfunction and hippocampal expression of calbindin d(28kd) (cb), a high affinity calcium-binding protein, in four melas patients, using post mortem hippocampal tissues. |
2013-02-11 |
2023-08-12 |
Not clear |
| Simon J Fung, MingChu Xi, JianHua Zhang, Sharon Sampogna, Michael H Chas. Apnea produces excitotoxic hippocampal synapses and neuronal apoptosis. Experimental neurology. vol 238. issue 2. 2013-01-21. PMID:22921462. |
in addition, to substantiate an anatomical basis for the cognitive dysfunction that occurs in osa patients, we examined the effects of apnea with respect to neurodegenerative changes (apoptosis) in the same hippocampal pathway. |
2013-01-21 |
2023-08-12 |
rat |
| Xiaobo Huang, Fen Wang, Wenqiang Chen, Yujing Chen, Ningqun Wang, Kristine von Maltza. Possible link between the cognitive dysfunction associated with diabetes mellitus and the neurotoxicity of methylglyoxal. Brain research. vol 1469. 2013-01-14. PMID:22750288. |
these data suggest a possible link between the cognitive dysfunction associated with diabetes mellitus and the neurotoxicity of mg, which may alter the expression levels of cleaved caspase-3, bcl-2 and bax in the hippocampus. |
2013-01-14 |
2023-08-12 |
rat |
| Marina O Ziehn, Andrea A Avedisian, Shannon M Dervin, Elizabeth A Umeda, Thomas J O'Dell, Rhonda R Voskuh. Therapeutic testosterone administration preserves excitatory synaptic transmission in the hippocampus during autoimmune demyelinating disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 36. 2012-11-16. PMID:22956822. |
furthermore, there are no treatments available to date to effectively prevent neurodegeneration and associated cognitive dysfunction in ms. we have recently demonstrated that the hippocampus is also targeted in experimental autoimmune encephalomyelitis (eae), the most widely used animal model of ms. |
2012-11-16 |
2023-08-12 |
mouse |
| Xiaoping Liu, Matthew J Betzenhauser, Steve Reiken, Albano C Meli, Wenjun Xie, Bi-Xing Chen, Ottavio Arancio, Andrew R Mark. Role of leaky neuronal ryanodine receptors in stress-induced cognitive dysfunction. Cell. vol 150. issue 5. 2012-11-05. PMID:22939628. |
stress-induced cognitive dysfunction, including deficits in learning and memory, and reduced long-term potentiation (ltp) at the hippocampal ca3-ca1 connection were rescued by oral administration of s107, a compound developed in our laboratory that stabilizes ryr2-calstabin2 interaction, or by genetic ablation of the ryr2 pka phosphorylation site at serine 2808. |
2012-11-05 |
2023-08-12 |
Not clear |
| Lisa M Savage, Joseph M Hall, Leticia S Resend. Translational rodent models of Korsakoff syndrome reveal the critical neuroanatomical substrates of memory dysfunction and recovery. Neuropsychology review. vol 22. issue 2. 2012-10-12. PMID:22528861. |
although the thalamus and mammillary bodies are the primary sites of neuropathology in ks, functional deactivation of the hippocampus and certain cortical regions also contributes to the chronic cognitive dysfunction reported in ks. |
2012-10-12 |
2023-08-12 |
Not clear |
| Takayuki Masaki, Futoshi Anan, Tsuyoshi Shimomura, Minoru Fujiki, Tetsunori Saikawa, Hironobu Yoshimats. Association between hippocampal volume and serum adiponectin in patients with type 2 diabetes mellitus. Metabolism: clinical and experimental. vol 61. issue 8. 2012-10-01. PMID:22405025. |
type 2 diabetes mellitus (dm) is associated with cognitive dysfunction and hippocampus volume. |
2012-10-01 |
2023-08-12 |
Not clear |