| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yunliang Wang, Honglei Yin, Jinfeng Li, Yuzhen Zhang, Bing Han, Zhilei Zeng, Nana Qiao, Xiaomei Cui, Jiyu Lou, Jing L. Amelioration of β-amyloid-induced cognitive dysfunction and hippocampal axon degeneration by curcumin is associated with suppression of CRMP-2 hyperphosphorylation. Neuroscience letters. vol 557 Pt B. 2014-08-18. PMID:24157857. |
amelioration of β-amyloid-induced cognitive dysfunction and hippocampal axon degeneration by curcumin is associated with suppression of crmp-2 hyperphosphorylation. |
2014-08-18 |
2023-08-12 |
rat |
| Wen-Jie Jin, Shan-Wu Feng, Zhou Feng, Shun-Mei Lu, Tao Qi, Yan-Ning Qia. Minocycline improves postoperative cognitive impairment in aged mice by inhibiting astrocytic activation. Neuroreport. vol 25. issue 1. 2014-07-31. PMID:24247278. |
this study aimed to examine the effect of minocycline on hippocampal astrocytes and long-term postoperative cognitive dysfunction in aged mice. |
2014-07-31 |
2023-08-12 |
mouse |
| Wan-Xia Xiong, Guo-Xia Zhou, Bei Wang, Zhang-Gang Xue, Lu Wang, Hui-Chuan Sun, Sheng-Jin G. Impaired spatial learning and memory after sevoflurane-nitrous oxide anesthesia in aged rats is associated with down-regulated cAMP/CREB signaling. PloS one. vol 8. issue 11. 2014-07-11. PMID:24260214. |
the current study demonstrated that down-regulation of camp/creb signaling, decrease of creb-dependent neurogenesis and neuronal survival in the hippocampus contributed to the neurotoxicity and cognitive dysfunction induced by general anesthesia with sevoflurane-nitrous oxide. |
2014-07-11 |
2023-08-12 |
rat |
| Shakuntala Savanthrapadian, Amy R Wolff, Barbara J Logan, Michael J Eckert, David K Bilkey, Wickliffe C Abraha. Enhanced hippocampal neuronal excitability and LTP persistence associated with reduced behavioral flexibility in the maternal immune activation model of schizophrenia. Hippocampus. vol 23. issue 12. 2014-07-09. PMID:23966340. |
the results are consistent with the hypothesis that hippocampal plasticity is altered in schizophrenia, and that this change in plasticity mechanisms may underlie some aspects of cognitive dysfunction in this disorder. |
2014-07-09 |
2023-08-12 |
rat |
| Jency Thomas, Manohar L Garg, Doug W Smit. Altered expression of histone and synaptic plasticity associated genes in the hippocampus of streptozotocin-induced diabetic mice. Metabolic brain disease. vol 28. issue 4. 2014-06-20. PMID:23832395. |
in the present study, we investigated the effects of diabetes-related hyperglycaemia on hippocampal gene expression, in order to identify potential mechanisms that might be associated with the cognitive dysfunction that develops with diabetes mellitus. |
2014-06-20 |
2023-08-12 |
mouse |
| Alice Krezymon, Kevin Richetin, Hélène Halley, Laurent Roybon, Jean-Michel Lassalle, Bernard Francès, Laure Verret, Claire Rampo. Modifications of hippocampal circuits and early disruption of adult neurogenesis in the tg2576 mouse model of Alzheimer's disease. PloS one. vol 8. issue 9. 2014-06-16. PMID:24086745. |
at advanced stages of alzheimer's disease, cognitive dysfunction is accompanied by severe alterations of hippocampal circuits that may largely underlie memory impairments. |
2014-06-16 |
2023-08-12 |
mouse |
| Vipan K Parihar, Bharathi Hattiangady, Bing Shuai, Ashok K Shett. Mood and memory deficits in a model of Gulf War illness are linked with reduced neurogenesis, partial neuron loss, and mild inflammation in the hippocampus. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 12. 2014-06-03. PMID:23807240. |
the results show the first evidence of an association between mood and cognitive dysfunction and hippocampal pathology epitomized by decreased neurogenesis, partial loss of principal neurons, and mild inflammation in a model of gwi. |
2014-06-03 |
2023-08-12 |
Not clear |
| Daisuke Ekuni, Yasumasa Endo, Takaaki Tomofuji, Tetsuji Azuma, Koichiro Irie, Kenta Kasuyama, Manabu Morit. Effects of apoE deficiency and occlusal disharmony on amyloid-beta production and spatial memory in rats. PloS one. vol 8. issue 9. 2014-05-26. PMID:24066161. |
in conclusion, occlusal disharmony induces cognitive dysfunction and aβ accumulation in the rat hippocampus, and the effects of occlusal disharmony on aβ accumulation and cognitive dysfunction were larger than those of apoe deficiency. |
2014-05-26 |
2023-08-12 |
rat |
| Ming-hua Chen, Yan Liao, Peng-fei Rong, Rong Hu, Guo-xin Lin, Wen Ouyan. Hippocampal volume reduction in elderly patients at risk for postoperative cognitive dysfunction. Journal of anesthesia. vol 27. issue 4. 2014-05-19. PMID:23371369. |
hippocampal volume reduction in elderly patients at risk for postoperative cognitive dysfunction. |
2014-05-19 |
2023-08-12 |
Not clear |
| Myoung-Hwa Lee, Niranjana D Amin, Arun Venkatesan, Tongguang Wang, Richa Tyagi, Harish C Pant, Avindra Nat. Impaired neurogenesis and neurite outgrowth in an HIV-gp120 transgenic model is reversed by exercise via BDNF production and Cdk5 regulation. Journal of neurovirology. vol 19. issue 5. 2014-05-07. PMID:23982957. |
in these patients, impairment of adult neurogenesis and neurite outgrowth in the hippocampus may contribute to cognitive dysfunction. |
2014-05-07 |
2023-08-12 |
mouse |
| Ramon Velazquez, Jessica A Ash, Brian E Powers, Christy M Kelley, Myla Strawderman, Zoe I Luscher, Stephen D Ginsberg, Elliott J Mufson, Barbara J Strup. Maternal choline supplementation improves spatial learning and adult hippocampal neurogenesis in the Ts65Dn mouse model of Down syndrome. Neurobiology of disease. vol 58. 2014-04-23. PMID:23643842. |
adult hippocampal (hp) neurogenesis is also deficient in ts65dn mice and may contribute to the observed cognitive dysfunction. |
2014-04-23 |
2023-08-12 |
mouse |
| Karina O Garcia, Felipe L M Ornellas, Priscila K Matsumoto Martin, Camilla L Patti, Luiz E Mello, Roberto Frussa-Filho, Sang W Han, Beatriz M Long. Therapeutic effects of the transplantation of VEGF overexpressing bone marrow mesenchymal stem cells in the hippocampus of murine model of Alzheimer's disease. Frontiers in aging neuroscience. vol 6. 2014-03-18. PMID:24639647. |
the present study investigates the effects of mscs overexpressing vegf in hippocampal neovascularization, cognitive dysfunction and senile plaques present in 2xtg-ad transgenic mice. |
2014-03-18 |
2023-08-12 |
mouse |
| Joana B Pereira, Carme Junqué, David Bartrés-Faz, Blanca Ramírez-Ruiz, Maria-Jose Marti, Eduardo Tolos. Regional vulnerability of hippocampal subfields and memory deficits in Parkinson's disease. Hippocampus. vol 23. issue 8. 2014-03-05. PMID:23553678. |
our findings indicate that learning deficits are associated with volume loss in subfields that act as input regions in the hippocampal circuit, suggesting that degeneration in these regions could be responsible for cognitive dysfunction in pd. |
2014-03-05 |
2023-08-12 |
Not clear |
| Erica W Taylor, Kai Wang, Amy R Nelson, Teruko M Bredemann, Kyle B Fraser, Sarah M Clinton, Rosemary Puckett, Richard B Marchase, John C Chatham, Lori L McMaho. O-GlcNAcylation of AMPA receptor GluA2 is associated with a novel form of long-term depression at hippocampal synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 1. 2014-02-24. PMID:24381264. |
our findings provide evidence that o-glcnacylation dynamically modulates hippocampal synaptic function and learning and memory, and suggest that altered o-glcnac levels could underlie cognitive dysfunction in neurological diseases. |
2014-02-24 |
2023-08-12 |
rat |
| Huang Nie, Zhengwu Peng, Ning Lao, Hailong Dong, Lize Xion. Effects of sevoflurane on self-renewal capacity and differentiation of cultured neural stem cells. Neurochemical research. vol 38. issue 8. 2014-02-06. PMID:23756731. |
to elucidate the pathogenesis of sevoflurane-induced cognitive dysfunction, we measured the effects of clinical sevoflurane doses on the survival, proliferation, and differentiation of hippocampal nscs. |
2014-02-06 |
2023-08-12 |
rat |
| Yushu Dong, Yue Li, Dayun Feng, Julei Wang, Hua Wen, Debao Liu, Dandan Zhao, Haiying Liu, Guodong Gao, Zhongmin Yin, Huaizhou Qi. Protective effect of HIF-1α against hippocampal apoptosis and cognitive dysfunction in an experimental rat model of subarachnoid hemorrhage. Brain research. vol 1517. 2014-01-17. PMID:23608228. |
protective effect of hif-1α against hippocampal apoptosis and cognitive dysfunction in an experimental rat model of subarachnoid hemorrhage. |
2014-01-17 |
2023-08-12 |
rat |
| Yushu Dong, Yue Li, Dayun Feng, Julei Wang, Hua Wen, Debao Liu, Dandan Zhao, Haiying Liu, Guodong Gao, Zhongmin Yin, Huaizhou Qi. Protective effect of HIF-1α against hippocampal apoptosis and cognitive dysfunction in an experimental rat model of subarachnoid hemorrhage. Brain research. vol 1517. 2014-01-17. PMID:23608228. |
the aim of the present study was to investigate the expression of hif-1α in the hippocampus and its possible protective effect against hippocampal apoptosis and cognitive dysfunction in a rat model of sah. |
2014-01-17 |
2023-08-12 |
rat |
| Ileana Marinescu, I Udriştoiu, D Marinesc. Choroid plexus calcification: clinical, neuroimaging and histopathological correlations in schizophrenia. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. vol 54. issue 2. 2013-12-27. PMID:23771083. |
neuroimaging shows that in patients with poor evolution, cognitive dysfunction and therapeutic resistance, the presence of choroid plexus calcification associated with hippocampal, frontal, temporoparietal and cerebellar atrophies. |
2013-12-27 |
2023-08-12 |
Not clear |
| Mira Didic, Olivier Felician, Emmanuel J Barbeau, Julien Mancini, Caroline Latger-Florence, Eve Tramoni, Mathieu Ceccald. Impaired visual recognition memory predicts Alzheimer's disease in amnestic mild cognitive impairment. Dementia and geriatric cognitive disorders. vol 35. issue 5-6. 2013-12-23. PMID:23572062. |
in the common form of alzheimer's disease (ad), neurofibrillary tangles, which are associated with cognitive dysfunction, initially develop in the anterior subhippocampal (perirhinal/entorhinal) cortex before reaching the hippocampus. |
2013-12-23 |
2023-08-12 |
Not clear |
| Dian-yu Jiang, Huang-wei L. [Effect of electroacupuncture on the cognitive function and plasma antibodies against beta-amyloid protein in aged rats with ketamine anesthesia]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. vol 31. issue 11. 2013-12-19. PMID:22303713. |
to study the effects of electroacupuncture (ea) on the changes of behavior after ketamine anesthesia, and changes of serum antibodies against beta-amyloid (abeta) and abeta protein in the hippocampus of aged rats, thus exploring the effects of ea on the cognitive dysfunction. |
2013-12-19 |
2023-08-12 |
rat |