| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Naruyoshi Fujiwara, Jun Shimizu, Kenji Takai, Nagisa Arimitsu, Yuji Ueda, Sueshige Wakisaka, Tomoko Suzuki, Noboru Suzuk. Cellular and molecular mechanisms of the restoration of human APP transgenic mouse cognitive dysfunction after transplant of human iPS cell-derived neural cells. Experimental neurology. vol 271. 2015-12-22. PMID:26196079. |
collectively, the grafted and host neurons may form positive feedback loops via neurotransmitter secretion in both the cerebral cortex and hippocampus, leading to alleviation of cognitive dysfunction in dementia model mice. |
2015-12-22 |
2023-08-13 |
mouse |
| Devsmita Das, Brian Medina, Mehmet Akif Baktir, Fatemeh S Mojabi, Atoossa Fahimi, Ravikumar Ponnusamy, Ahmad Saleh. Increased incidence of intermittent hypoxemia in the Ts65Dn mouse model of Down syndrome. Neuroscience letters. vol 604. 2015-12-21. PMID:26240993. |
while these mice consistently show failure in learning and memory along with functional and structural abnormalities in the hippocampal region, the underlying mechanisms behind cognitive dysfunction remain to be fully elucidated. |
2015-12-21 |
2023-08-13 |
mouse |
| Penghui Wei, Qingshen Liu, Dong Li, Qiang Zheng, Jinfeng Zhou, Jianjun L. Acute nicotine treatment attenuates lipopolysaccharide-induced cognitive dysfunction by increasing BDNF expression and inhibiting neuroinflammation in the rat hippocampus. Neuroscience letters. vol 604. 2015-12-21. PMID:26259694. |
acute nicotine treatment attenuates lipopolysaccharide-induced cognitive dysfunction by increasing bdnf expression and inhibiting neuroinflammation in the rat hippocampus. |
2015-12-21 |
2023-08-13 |
rat |
| Penghui Wei, Qingshen Liu, Dong Li, Qiang Zheng, Jinfeng Zhou, Jianjun L. Acute nicotine treatment attenuates lipopolysaccharide-induced cognitive dysfunction by increasing BDNF expression and inhibiting neuroinflammation in the rat hippocampus. Neuroscience letters. vol 604. 2015-12-21. PMID:26259694. |
taken together, acute nicotine administration attenuated lps-induced cognitive dysfunction, and this neuroprotective effect may be related to the up-regulation of bdnf and the inhibition of neuroinflammation and apoptosis-related proteins in the dorsal hippocampus. |
2015-12-21 |
2023-08-13 |
rat |
| Kazuhiro Takuma, Yuta Hara, Shunsuke Kataoka, Takuya Kawanai, Yuko Maeda, Ryo Watanabe, Erika Takano, Atsuko Hayata-Takano, Hitoshi Hashimoto, Yukio Ago, Toshio Matsud. Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism. Pharmacology, biochemistry, and behavior. vol 126. 2015-11-09. PMID:25240644. |
in addition, we examined whether the cognitive dysfunction is associated with hippocampal dendritic morphological changes. |
2015-11-09 |
2023-08-13 |
mouse |
| Kazuhiro Takuma, Yuta Hara, Shunsuke Kataoka, Takuya Kawanai, Yuko Maeda, Ryo Watanabe, Erika Takano, Atsuko Hayata-Takano, Hitoshi Hashimoto, Yukio Ago, Toshio Matsud. Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism. Pharmacology, biochemistry, and behavior. vol 126. 2015-11-09. PMID:25240644. |
these findings suggest that prenatal vpa-induced cognitive dysfunction is associated with changes in hippocampal dendritic spine morphology. |
2015-11-09 |
2023-08-13 |
mouse |
| Ataç Sönmez, Oya Sayın, Seren Gülşen Gürgen, Meryem Çalişi. Neuroprotective effects of MK-801 against traumatic brain injury in immature rats. Neuroscience letters. vol 597. 2015-10-19. PMID:25943283. |
the aims of the present study were to determine: (i) the short term effects of mk-801 on hippocampal bdnf, ngf and nmda receptor immunoreactivity and neuron density in hippocampus (ii) long term effects of mk-801 on cognitive dysfunction following tbi in the immature rats. |
2015-10-19 |
2023-08-13 |
rat |
| Ieda de Fátima Oliveira-Silva, Silvia R Castanheira Pereira, Paula A Fernandes, Andrea F Ribeiro, Rita G W Pires, Angela Maria Ribeir. Mild thiamine deficiency and chronic ethanol consumption modulate acetylcholinesterase activity change and spatial memory performance in a water maze task. Journal of molecular neuroscience : MN. vol 55. issue 1. 2015-09-10. PMID:24770900. |
in the present work, the chronic effects of ethanol and its association to a mild thiamine deficiency episode (subclinical model) on neocortical and hippocampal acetylcholinesterase activity were assessed along with their possible association to spatial cognitive dysfunction. |
2015-09-10 |
2023-08-13 |
Not clear |
| Alicia A McNeely, Joel Ramirez, Sean M Nestor, Jiali Zhao, Fuqiang Gao, Alex Kiss, Donald T Stuss, Sandra E Blac. Cholinergic subcortical hyperintensities in Alzheimer's disease patients from the Sunnybrook Dementia Study: relationships with cognitive dysfunction and hippocampal atrophy. Journal of Alzheimer's disease : JAD. vol 43. issue 3. 2015-08-21. PMID:25114078. |
cholinergic subcortical hyperintensities in alzheimer's disease patients from the sunnybrook dementia study: relationships with cognitive dysfunction and hippocampal atrophy. |
2015-08-21 |
2023-08-13 |
Not clear |
| Jung Hye Byeon, Gun-Ha Kim, Joo Yeon Kim, Woong Sun, Hyun Kim, Baik-Lin Eu. Cognitive Dysfunction and Hippocampal Damage Induced by Hypoxic-Ischemic Brain Injury and Prolonged Febrile Convulsions in Immature Rats. Journal of Korean Neurosurgical Society. vol 58. issue 1. 2015-08-17. PMID:26279809. |
cognitive dysfunction and hippocampal damage induced by hypoxic-ischemic brain injury and prolonged febrile convulsions in immature rats. |
2015-08-17 |
2023-08-13 |
rat |
| Yiyun Cao, Cheng Ni, Zhengqian Li, Lunxu Li, Yajie Liu, Chunyi Wang, Yanfeng Zhong, Dehua Cui, Xiangyang Gu. Isoflurane anesthesia results in reversible ultrastructure and occludin tight junction protein expression changes in hippocampal blood-brain barrier in aged rats. Neuroscience letters. vol 587. 2015-08-10. PMID:25524410. |
in this study, the effects of isoflurane exposure on the hippocampal blood-brain barrier (bbb) in aged rats were investigated because it was previously shown that bbb disruption involves in cognitive dysfunction. |
2015-08-10 |
2023-08-13 |
rat |
| Hongyu Xue, Junbo Wang, Yuxia Zhuang, Guizhen Ga. [Hippocampal neuron damage and cognitive dysfunction of diabetic Wistar rats]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi. vol 31. issue 6. 2015-07-17. PMID:25868249. |
[hippocampal neuron damage and cognitive dysfunction of diabetic wistar rats]. |
2015-07-17 |
2023-08-13 |
rat |
| Hongyu Xue, Junbo Wang, Yuxia Zhuang, Guizhen Ga. [Hippocampal neuron damage and cognitive dysfunction of diabetic Wistar rats]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi. vol 31. issue 6. 2015-07-17. PMID:25868249. |
this study aimed to explore the cognitive dysfunction of and hippocampal neuron damage to wistar rats with stz-induced diabetes at different morbidity time. |
2015-07-17 |
2023-08-13 |
rat |
| Shengbin Huang, Yongfu Wang, Xueqi Gan, Du Fang, Changjia Zhong, Long Wu, Gang Hu, Alexander A Sosunov, Guy M McKhann, Haiyang Yu, Shirley ShiDu Ya. Drp1-mediated mitochondrial abnormalities link to synaptic injury in diabetes model. Diabetes. vol 64. issue 5. 2015-06-29. PMID:25412623. |
diabetes has adverse effects on the brain, especially the hippocampus, which is particularly susceptible to synaptic injury and cognitive dysfunction. |
2015-06-29 |
2023-08-13 |
mouse |
| Takashi Iwamoto, Yasuo Ouch. Emerging evidence of insulin-like growth factor 2 as a memory enhancer: a unique animal model of cognitive dysfunction with impaired adult neurogenesis. Reviews in the neurosciences. vol 25. issue 4. 2015-05-26. PMID:24778346. |
here, we would like to review the rapidly growing world of igf2 in cognitive neuroscience and introduce the evidence that its deficit is indeed involved in the impairment of the hippocampal neurogenesis and cognitive dysfunction in the model mouse of 22q11.2 deletion syndrome, which deletes dgcr8, a critical gene for microrna processing. |
2015-05-26 |
2023-08-13 |
mouse |
| Hong Ming, Rui Chen, Jing Wang, Jingmei Ju, Li Sun, Guoxing Zhan. [Role of hippocampal neuronal intracellular calcium overload in modulating cognitive dysfunction and the neuronprotective effect of mematine in a mouse model of chronic intermittent hypoxia]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases. vol 37. issue 12. 2015-05-20. PMID:25609125. |
[role of hippocampal neuronal intracellular calcium overload in modulating cognitive dysfunction and the neuronprotective effect of mematine in a mouse model of chronic intermittent hypoxia]. |
2015-05-20 |
2023-08-13 |
mouse |
| Hong Ming, Rui Chen, Jing Wang, Jingmei Ju, Li Sun, Guoxing Zhan. [Role of hippocampal neuronal intracellular calcium overload in modulating cognitive dysfunction and the neuronprotective effect of mematine in a mouse model of chronic intermittent hypoxia]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases. vol 37. issue 12. 2015-05-20. PMID:25609125. |
to investigate the role of hippocampal intracellular calcium overload in modulating cognitive dysfunction and the neuronprotective effect of mematine in a mouse model of chronic intermittent hypoxia. |
2015-05-20 |
2023-08-13 |
mouse |
| Yuta Yoshino, Mitsue Ishisaka, Saori Tsujii, Masamitsu Shimazawa, Hideaki Har. Glucagon-like peptide-1 protects the murine hippocampus against stressors via Akt and ERK1/2 signaling. Biochemical and biophysical research communications. vol 458. issue 2. 2015-05-01. PMID:25660451. |
alzheimer's disease (ad) is a common neurodegenerative disease characterized by cognitive dysfunction and neuronal cell death in the hippocampus and cerebral cortex. |
2015-05-01 |
2023-08-13 |
mouse |
| Zhimei Qiao, Kangning Xie, Kai Liu, Guoliang L. Decreased neuronal bursting and phase synchrony in the hippocampus of streptozotocin diabetic rats. Journal of diabetes research. vol 2014. 2015-04-15. PMID:25093193. |
previous findings from neuroanatomical and in vitro electrophysiological studies showed that the structure and function of the hippocampus is impaired in diabetes, which may underlie the cognitive dysfunction induced by diabetes. |
2015-04-15 |
2023-08-13 |
rat |
| Nai-Kui Liu, Yi-Ping Zhang, Jian Zou, Tom Verhovshek, Chen Chen, Qing-Bo Lu, Chandler L Walker, Christopher B Shields, Xiao-Ming X. A semicircular controlled cortical impact produces long-term motor and cognitive dysfunction that correlates well with damage to both the sensorimotor cortex and hippocampus. Brain research. vol 1576. 2015-03-31. PMID:24905625. |
a semicircular controlled cortical impact produces long-term motor and cognitive dysfunction that correlates well with damage to both the sensorimotor cortex and hippocampus. |
2015-03-31 |
2023-08-13 |
mouse |