| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V I Reus, O M Wolkowit. Antiglucocorticoid drugs in the treatment of depression. Expert opinion on investigational drugs. vol 10. issue 10. 2002-02-28. PMID:11772285. |
in patients with endogenous depression, hypercortisolaemia is associated with cognitive dysfunction and possibly a decrease in hippocampal volume. |
2002-02-28 |
2023-08-12 |
Not clear |
| H Wolf, M Grunwald, F Kruggel, S G Riedel-Heller, S Angerhöfer, A Hojjatoleslami, A Hensel, T Arendt, H Gert. Hippocampal volume discriminates between normal cognition; questionable and mild dementia in the elderly. Neurobiology of aging. vol 22. issue 2. 2001-05-03. PMID:11182467. |
we conclude that hippocampal atrophy is sensitive to detect cognitive dysfunction and subjects at risk for alzheimer's disease in the elderly population. |
2001-05-03 |
2023-08-12 |
human |
| M J Leoni, X H Chen, A L Mueller, J Cheney, T K McIntosh, D H Smit. NPS 1506 attenuates cognitive dysfunction and hippocampal neuron death following brain trauma in the rat. Experimental neurology. vol 166. issue 2. 2001-01-04. PMID:11085909. |
nps 1506 attenuates cognitive dysfunction and hippocampal neuron death following brain trauma in the rat. |
2001-01-04 |
2023-08-12 |
rat |
| K Ikeda, Y Iwasaki, M Kinoshita, S Marubuchi, S On. T-588, a novel neuroprotective agent, delays progression of neuromuscular dysfunction in wobbler mouse motoneuron disease. Brain research. vol 858. issue 1. 2000-04-25. PMID:10700601. |
r(-)-1-(benzo[b]thiophen-5-yl)-2-[2-(n,n-diethylamino) ethoxy]ethanol hydrochloride (t-588) enhances acetylcholine release from the frontal cortex and hippocampus in rats, and can ameliorate cognitive dysfunction in various amnesia models of rodents. |
2000-04-25 |
2023-08-12 |
mouse |
| T Kadar, S Dachir, B Shukitt-Hale, A Lev. Sub-regional hippocampal vulnerability in various animal models leading to cognitive dysfunction. Journal of neural transmission (Vienna, Austria : 1996). vol 105. issue 8-9. 1999-03-16. PMID:9869331. |
sub-regional hippocampal vulnerability in various animal models leading to cognitive dysfunction. |
1999-03-16 |
2023-08-12 |
rat |
| J L Yau, J Noble, J R Seck. Site-specific regulation of corticosteroid and serotonin receptor subtype gene expression in the rat hippocampus following 3,4-methylenedioxymethamphetamine: role of corticosterone and serotonin. Neuroscience. vol 78. issue 1. 1997-08-01. PMID:9135093. |
abnormal interactions between serotonin (5-hydroxytryptamine) and glucocorticoids, notably in the hippocampus, may underpin neuroendocrine, affective and cognitive dysfunction in depression and ageing. |
1997-08-01 |
2023-08-12 |
rat |
| N McNaughto. Cognitive dysfunction resulting from hippocampal hyperactivity--a possible cause of anxiety disorder? Pharmacology, biochemistry, and behavior. vol 56. issue 4. 1997-07-07. PMID:9130284. |
cognitive dysfunction resulting from hippocampal hyperactivity--a possible cause of anxiety disorder? |
1997-07-07 |
2023-08-12 |
Not clear |
| J Golomb, M J de Leon, A E George, A Kluger, A Convit, H Rusinek, S de Santi, A Litt, S H Foo, S H Ferri. Hippocampal atrophy correlates with severe cognitive impairment in elderly patients with suspected normal pressure hydrocephalus. Journal of neurology, neurosurgery, and psychiatry. vol 57. issue 5. 1994-07-07. PMID:8201330. |
it was concluded that hippocampal atrophy is associated with severe cognitive dysfunction in many elderly patients with a diagnosis of nph. |
1994-07-07 |
2023-08-12 |
Not clear |
| L S Prichep, E R John, S H Ferris, B Reisberg, M Almas, K Alper, R Cancr. Quantitative EEG correlates of cognitive deterioration in the elderly. Neurobiology of aging. vol 15. issue 1. 1994-05-13. PMID:8159266. |
a possible relationship between hippocampal dysfunction, cognitive deterioration, and theta abnormalities is discussed in relation to these findings. |
1994-05-13 |
2023-08-12 |
Not clear |
| E A Werber, J Chapman, A Arlazorof. Brainstem auditory evoked potentials in experimental autoimmune dementia. Neuroscience letters. vol 151. issue 2. 1993-07-08. PMID:8506086. |
cognitive dysfunction may be induced in rats by immunization with cholinergic neuronal antigens and is associated with degeneration of nuclei in the septum and hippocampus and white matter tracts in the forebrain. |
1993-07-08 |
2023-08-12 |
rat |