| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kumi Hayashi, Soichi Kurioka, Toru Yamaguchi, Miwa Morita, Ippei Kanazawa, Hirofumi Takase, Akihiko Wada, Hajime Kitagaki, Atsushi Nagai, Hirokazu Bokura, Shuhei Yamaguchi, Toshitsugu Sugimot. Association of cognitive dysfunction with hippocampal atrophy in elderly Japanese people with type 2 diabetes. Diabetes research and clinical practice. vol 94. issue 2. 2012-03-12. PMID:21835484. |
association of cognitive dysfunction with hippocampal atrophy in elderly japanese people with type 2 diabetes. |
2012-03-12 |
2023-08-12 |
Not clear |
| Ashok K Shett. Promise of resveratrol for easing status epilepticus and epilepsy. Pharmacology & therapeutics. vol 131. issue 3. 2011-12-07. PMID:21554899. |
next, the detrimental effects of acute seizures or status epilepticus on the hippocampus and the implications of post-status epilepticus changes in the hippocampus towards the occurrence of chronic epilepsy and cognitive dysfunction are summarized. |
2011-12-07 |
2023-08-12 |
Not clear |
| Xiao-Dong Wang, Gerhard Rammes, Igor Kraev, Miriam Wolf, Claudia Liebl, Sebastian H Scharf, Courtney J Rice, Wolfgang Wurst, Florian Holsboer, Jan M Deussing, Tallie Z Baram, Michael G Stewart, Marianne B Müller, Mathias V Schmid. Forebrain CRF₁ modulates early-life stress-programmed cognitive deficits. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 38. 2011-12-07. PMID:21940453. |
persistent elevations of hippocampal corticotropin-releasing factor (crf), acting through crf receptor 1 (crf₁), in experimental models of early-life stress have suggested a role for this endogenous stress hormone in the resulting structural modifications and cognitive dysfunction. |
2011-12-07 |
2023-08-12 |
mouse |
| N Realini, D Vigano', C Guidali, E Zamberletti, T Rubino, D Parolar. Chronic URB597 treatment at adulthood reverted most depressive-like symptoms induced by adolescent exposure to THC in female rats. Neuropharmacology. vol 60. issue 2-3. 2011-11-22. PMID:20850463. |
since it has been reported that deficits in adult hippocampal neurogenesis may underlie the cognitive dysfunction seen in depression, we then survey cell proliferation in the dentate gyrus of the hippocampus. |
2011-11-22 |
2023-08-12 |
rat |
| C-H Yu, G-S Song, J-Y Yhee, J-H Kim, K-S Im, W-G Nho, J-H Lee, J-H Su. Histopathological and immunohistochemical comparison of the brain of human patients with Alzheimer's disease and the brain of aged dogs with cognitive dysfunction. Journal of comparative pathology. vol 145. issue 1. 2011-10-14. PMID:21256508. |
changes in the brain of aged dogs with cognitive dysfunction were compared with those in the brain of patients with ad of braak stage v. immunohistochemically, aβ deposition, phosphorylated tau ser396 (p-tau ser396) and ubiquitin were observed in the parietal cortex and hippocampus of aged dogs with cognitive dysfunction. |
2011-10-14 |
2023-08-12 |
human |
| C L Liu, Y X Xu, Y Zhan, H L Hu, X M Jia, G H Chen, D F Zh. Effect of thyroxine on synaptotagmin 1 and SNAP-25 expression in dorsal hippocampus of adult-onset hypothyroid rats. Journal of endocrinological investigation. vol 34. issue 4. 2011-09-30. PMID:20543552. |
adult-onset hypothyroidism causes cognitive dysfunctions of learning and memory, in which many synaptic proteins in hippocampus are involved. |
2011-09-30 |
2023-08-12 |
rat |
| Yu-Gang Jiang, Hong-Yun Fang, Wei Pang, Jing Liu, Hao Lu, Qiang Ma, Heng-Tong Fan. Depressed hippocampal MEK/ERK phosphorylation correlates with impaired cognitive and synaptic function in zinc-deficient rats. Nutritional neuroscience. vol 14. issue 2. 2011-09-12. PMID:21605499. |
an experiment was performed to observe changes of mitogen-activated protein kinase erk (mek)/extracellular signal-regulated kinase (erk) signaling pathways in the hippocampus of zinc-deficient (zd) rats and the correlation with cognitive dysfunction. |
2011-09-12 |
2023-08-12 |
rat |
| Tsuyoshi Shimomura, Futoshi Anan, Takayuki Masaki, Yoshikazu Umeno, Nobuoki Eshima, Tetsunori Saikawa, Hironobu Yoshimatsu, Minoru Fujiki, Hidenori Kobayash. Homocysteine levels are associated with hippocampus volume in type 2 diabetic patients. European journal of clinical investigation. vol 41. issue 7. 2011-09-09. PMID:21250986. |
elevated total plasma homocysteine (thcy) levels are associated with cognitive dysfunction, in which changes in the hippocampus plausibly play a pivotal role. |
2011-09-09 |
2023-08-12 |
Not clear |
| Thomas E Nelson, Christine Hao, Jessica Manos, R M Ransohoff, Donna L Gruo. Altered hippocampal synaptic transmission in transgenic mice with astrocyte-targeted enhanced CCL2 expression. Brain, behavior, and immunity. vol 25 Suppl 1. 2011-08-08. PMID:21356306. |
these results show that ccl2, which is known to be chronically produced at elevated levels within the cns in a number of cns disorders, can significantly alter hippocampal function and implicate a role for ccl2 in the cognitive dysfunction associated with these cns disorders. |
2011-08-08 |
2023-08-12 |
mouse |
| Ting Yang, Lei Zhuang, Niccolò Terrando, Xinmin Wu, Mark R Jonhson, Mervyn Maze, Daqing M. A clinically relevant model of perinatal global ischemic brain damage in rats. Brain research. vol 1383. 2011-08-02. PMID:21281606. |
these data demonstrate that perinatal ischemic injury leads to neuronal death in the hippocampus and long-lasting cognitive dysfunction. |
2011-08-02 |
2023-08-12 |
rat |
| Daisuke Kodama, Hideki Ono, Mitsuo Tanab. Increased hippocampal glycine uptake and cognitive dysfunction after peripheral nerve injury. Pain. vol 152. issue 4. 2011-07-26. PMID:21295405. |
increased hippocampal glycine uptake and cognitive dysfunction after peripheral nerve injury. |
2011-07-26 |
2023-08-12 |
mouse |
| Ahmed A Moustafa, Szabolcs Keri, Mohammad M Herzallah, Catherine E Myers, Mark A Gluc. A neural model of hippocampal-striatal interactions in associative learning and transfer generalization in various neurological and psychiatric patients. Brain and cognition. vol 74. issue 2. 2011-06-30. PMID:20728258. |
this task has been used to test cognitive dysfunction in various patient populations with damages to the hippocampal region and basal ganglia, including studies of patients with parkinson's disease (pd), schizophrenia, basal forebrain amnesia, and hippocampal atrophy. |
2011-06-30 |
2023-08-12 |
Not clear |
| Futoshi Anan, Takayuki Masaki, Tsuyoshi Shimomura, Minoru Fujiki, Yoshikazu Umeno, Nobuoki Eshima, Tetsunori Saikawa, Hironobu Yoshimats. High-sensitivity C-reactive protein is associated with hippocampus volume in nondementia patients with type 2 diabetes mellitus. Metabolism: clinical and experimental. vol 60. issue 4. 2011-05-23. PMID:20537668. |
the elevated level of high-sensitivity c-reactive protein (hscrp) is associated with cognitive dysfunction, for which changes in the hippocampus plausibly play a pivotal role. |
2011-05-23 |
2023-08-12 |
human |
| Jorge J Palop, Lennart Mucke, Erik D Roberso. Quantifying biomarkers of cognitive dysfunction and neuronal network hyperexcitability in mouse models of Alzheimer's disease: depletion of calcium-dependent proteins and inhibitory hippocampal remodeling. Methods in molecular biology (Clifton, N.J.). vol 670. 2011-05-02. PMID:20967595. |
quantifying biomarkers of cognitive dysfunction and neuronal network hyperexcitability in mouse models of alzheimer's disease: depletion of calcium-dependent proteins and inhibitory hippocampal remodeling. |
2011-05-02 |
2023-08-12 |
mouse |
| Adriana da Rocha Tomé, Chistiane Mendes Feitosa, Rivelilson Mendes de Freita. Neuronal damage and memory deficits after seizures are reversed by ascorbic acid? Arquivos de neuro-psiquiatria. vol 68. issue 4. 2011-04-05. PMID:20730313. |
aa can reverse cognitive dysfunction observed in rats with seizures as well as decrease neuronal injury in rat hippocampus. |
2011-04-05 |
2023-08-12 |
rat |
| Petra Huehnchen, Timour Prozorovski, Philipp Klaissle, Anne Lesemann, Jens Ingwersen, Susanne A Wolf, Andreas Kupsch, Orhan Aktas, Barbara Steine. Modulation of adult hippocampal neurogenesis during myelin-directed autoimmune neuroinflammation. Glia. vol 59. issue 1. 2011-02-25. PMID:20967885. |
in chronic autoimmune diseases of the central nervous system (cns) such as multiple sclerosis (ms) clinical signs of cognitive dysfunction have been associated with structural changes in the hippocampus. |
2011-02-25 |
2023-08-12 |
mouse |
| Gouda K Helal, Abdulaziz M Aleisa, Omayma K Helal, Salim S Al-Rejaie, Abdulaziz A Al-Yahya, Abdulhakeem A Al-Majed, Othman A Al-Shabana. Metallothionein induction reduces caspase-3 activity and TNFalpha levels with preservation of cognitive function and intact hippocampal neurons in carmustine-treated rats. Oxidative medicine and cellular longevity. vol 2. issue 1. 2011-01-26. PMID:20046642. |
the present study aimed to explore the effect of mt induction on carmustine (bcnu)-induced hippocampal cognitive dysfunction in rats. |
2011-01-26 |
2023-08-12 |
rat |
| Niccolò Terrando, Claudia Monaco, Daqing Ma, Brian M J Foxwell, Marc Feldmann, Mervyn Maz. Tumor necrosis factor-alpha triggers a cytokine cascade yielding postoperative cognitive decline. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 47. 2011-01-20. PMID:21041647. |
a variety of mechanisms have been proposed, and exploring the role of inflammation, we recently reported the role of il-1β in the hippocampus after surgery in mice with postoperative cognitive dysfunction. |
2011-01-20 |
2023-08-12 |
mouse |
| Kazuya Motomura, Masatoshi Ogura, Atsushi Natsume, Hidenori Yokoyama, Toshihiko Wakabayash. A free-radical scavenger protects the neural progenitor cells in the dentate subgranular zone of the hippocampus from cell death after X-irradiation. Neuroscience letters. vol 485. issue 1. 2011-01-04. PMID:20804818. |
it has been elucidated that cognitive dysfunction following cranial radiotherapy might be linked to the oxidative stress-induced impairment of hippocampal neurogenesis that is mediated by proliferating neural stem or progenitor cells. |
2011-01-04 |
2023-08-12 |
human |
| Chandramohan Wakade, Sangeetha Sukumari-Ramesh, Melissa D Laird, Krishnan M Dhandapani, John R Vende. Delayed reduction in hippocampal postsynaptic density protein-95 expression temporally correlates with cognitive dysfunction following controlled cortical impact in mice. Journal of neurosurgery. vol 113. issue 6. 2011-01-03. PMID:20397893. |
delayed reduction in hippocampal postsynaptic density protein-95 expression temporally correlates with cognitive dysfunction following controlled cortical impact in mice. |
2011-01-03 |
2023-08-12 |
mouse |