| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Juan J Canale. Comparative neuroscience of stimulant-induced memory dysfunction: role for neurogenesis in the adult hippocampus. Behavioural pharmacology. vol 21. issue 5-6. 2010-11-24. PMID:20700045. |
the discovery that the addictive drugs impair neurogenesis in the adult hippocampus has prompted the elaboration of new biological hypotheses to explain addiction and drug-induced cognitive dysfunction. |
2010-11-24 |
2023-08-12 |
Not clear |
| Karen Sooy, Scott P Webster, June Noble, Margaret Binnie, Brian R Walker, Jonathan R Seckl, Joyce L W Ya. Partial deficiency or short-term inhibition of 11beta-hydroxysteroid dehydrogenase type 1 improves cognitive function in aging mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 41. 2010-11-04. PMID:20943927. |
excess gc action exerts deleterious effects on the hippocampus and causes impaired spatial memory, a key feature of age-related cognitive dysfunction. |
2010-11-04 |
2023-08-12 |
mouse |
| Staci D Bilbo, Verne Tsan. Enduring consequences of maternal obesity for brain inflammation and behavior of offspring. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 24. issue 6. 2010-07-21. PMID:20124437. |
we assessed whether peripheral inflammation in maternal obesity may be transferred to the offspring brain, in particular, the hippocampus, and thereby result in cognitive dysfunction. |
2010-07-21 |
2023-08-12 |
rat |
| b' Semra Ulusoy Kaymak, Ba\\xc5\\x9faran Demir, Senem Sent\\xc3\\xbcrk, Ilkan Tatar, M Mustafa Aldur, Berna Ulu\\xc4\\x9. Hippocampus, glucocorticoids and neurocognitive functions in patients with first-episode major depressive disorders. European archives of psychiatry and clinical neuroscience. vol 260. issue 3. 2010-06-30. PMID:19756819.' |
the aim of this study was to determine whether there was any relationship between hippocampal volume, and glucocorticoid regulation, and cognitive dysfunctions in drug-naïve major depressive disorder (mdd) patients during their first episode. |
2010-06-30 |
2023-08-12 |
human |
| Robert Freedman, Dan Goldowit. Studies on the hippocampal formation: From basic development to clinical applications: Studies on schizophrenia. Progress in neurobiology. vol 90. issue 2. 2010-05-26. PMID:19853005. |
evidence for the role of the alpha 7-nicotinic acetylcholine receptor in the development and function of these neurons in rodents has led to human trials of nicotinic agonists for cognitive dysfunction in schizophrenia and the possibility of improving hippocampal development in children at risk for schizophrenia by perinatal supplementation with choline, which can act as an alpha 7-nicotinic acetylcholine receptor agonist. |
2010-05-26 |
2023-08-12 |
human |
| Eun Ok Lee, Hee Ju Park, Jihee Lee Kang, Hye-Sun Kim, Young Hae Chon. Resveratrol reduces glutamate-mediated monocyte chemotactic protein-1 expression via inhibition of extracellular signal-regulated kinase 1/2 pathway in rat hippocampal slice cultures. Journal of neurochemistry. vol 112. issue 6. 2010-04-30. PMID:20050970. |
additionally, our data reveal an anti-inflammatory mechanism of resveratrol involving the inactivation of the erk1/2 pathway in the hippocampus, which is linked principally to ad-associated cognitive dysfunction. |
2010-04-30 |
2023-08-12 |
rat |
| Rivelilson Mendes de Freita. Lipoic Acid increases hippocampal choline acetyltransferase and acetylcholinesterase activities and improvement memory in epileptic rats. Neurochemical research. vol 35. issue 1. 2010-04-19. PMID:19669875. |
lipoic acid can reverse cognitive dysfunction observed in seized rats as well as increase the chat and ache activities in hippocampus of rats prior to pilocarpine-induced seizures, suggesting that this antioxidant could be used in clinic treatment of epilepsy. |
2010-04-19 |
2023-08-12 |
rat |
| Ze-Qiang Qu, Yan Zhou, Yuan-Shan Zeng, Yan Li, Peter Chun. Pretreatment with Rhodiola rosea extract reduces cognitive impairment induced by intracerebroventricular streptozotocin in rats: implication of anti-oxidative and neuroprotective effects. Biomedical and environmental sciences : BES. vol 22. issue 4. 2010-02-05. PMID:19950527. |
to investigate the pretreatment effects of rhodiola rosea (r. rosea) extract on cognitive dysfunction, oxidative stress in hippocampus and hippocampal neuron injury in a rat model of alzheimer's disease (ad). |
2010-02-05 |
2023-08-12 |
rat |
| Xuena Zhang, Yang Liu, Chunsheng Feng, Shuguang Yang, Yun Wang, An-shi Wu, Yun Yu. Proteomic profiling of the insoluble fractions in the rat hippocampus post-propofol anesthesia. Neuroscience letters. vol 465. issue 2. 2010-01-14. PMID:19682543. |
this study aimed to provide evidence that changes in insoluble proteome in rat hippocampus may be involved in molecular mechanism of cognitive dysfunction following propofol anesthesia. |
2010-01-14 |
2023-08-12 |
rat |
| Hung-Ming Chang, Un-In Wu, Chyn-Tair La. Melatonin preserves longevity protein (sirtuin 1) expression in the hippocampus of total sleep-deprived rats. Journal of pineal research. vol 47. issue 3. 2010-01-12. PMID:19627456. |
sleep disorders cause cognitive dysfunction in which impaired neuronal plasticity in the hippocampus may underline the molecular mechanisms of this deficiency. |
2010-01-12 |
2023-08-12 |
rat |
| Dan V Iosifescu, Constance M Moore, Thilo Deckersbach, Claire A Tilley, Michael J Ostacher, Gary S Sachs, Andrew A Nierenber. Galantamine-ER for cognitive dysfunction in bipolar disorder and correlation with hippocampal neuronal viability: a proof-of-concept study. CNS neuroscience & therapeutics. vol 15. issue 4. 2010-01-07. PMID:19889129. |
galantamine-er for cognitive dysfunction in bipolar disorder and correlation with hippocampal neuronal viability: a proof-of-concept study. |
2010-01-07 |
2023-08-12 |
human |
| David J Mancuso, Paul Kotzbauer, David F Wozniak, Harold F Sims, Christopher M Jenkins, Shaoping Guan, Xianlin Han, Kui Yang, Gang Sun, Ibrahim Malik, Sara Conyers, Karen G Green, Robert E Schmidt, Richard W Gros. Genetic ablation of calcium-independent phospholipase A2{gamma} leads to alterations in hippocampal cardiolipin content and molecular species distribution, mitochondrial degeneration, autophagy, and cognitive dysfunction. The Journal of biological chemistry. vol 284. issue 51. 2010-01-06. PMID:19840936. |
genetic ablation of calcium-independent phospholipase a2{gamma} leads to alterations in hippocampal cardiolipin content and molecular species distribution, mitochondrial degeneration, autophagy, and cognitive dysfunction. |
2010-01-06 |
2023-08-12 |
mouse |
| David J Mancuso, Paul Kotzbauer, David F Wozniak, Harold F Sims, Christopher M Jenkins, Shaoping Guan, Xianlin Han, Kui Yang, Gang Sun, Ibrahim Malik, Sara Conyers, Karen G Green, Robert E Schmidt, Richard W Gros. Genetic ablation of calcium-independent phospholipase A2{gamma} leads to alterations in hippocampal cardiolipin content and molecular species distribution, mitochondrial degeneration, autophagy, and cognitive dysfunction. The Journal of biological chemistry. vol 284. issue 51. 2010-01-06. PMID:19840936. |
genetic ablation of calcium-independent phospholipase a(2)gamma (ipla(2)gamma) results in profound alterations in hippocampal phospholipid metabolism and mitochondrial phospholipid homeostasis resulting in enlarged and degenerating mitochondria leading to autophagy and cognitive dysfunction. |
2010-01-06 |
2023-08-12 |
mouse |
| Futoshi Anan, Takayuki Masaki, Tsuyoshi Shimomura, Minoru Fujiki, Yoshikazu Umeno, Nobuoki Eshima, Tetsunori Saikawa, Hironobu Yoshimats. Abdominal visceral fat accumulation is associated with hippocampus volume in non-dementia patients with type 2 diabetes mellitus. NeuroImage. vol 49. issue 1. 2010-01-04. PMID:19683583. |
obesity is associated with cognitive dysfunction, for which changes in the hippocampus plausibly play a pivotal role. |
2010-01-04 |
2023-08-12 |
human |
| Puneet Kumar, Anil Kuma. Protective role of sertraline against 3-nitropropionic acid-induced cognitive dysfunction and redox ratio in striatum, cortex and hippocampus of rat brain. Indian journal of experimental biology. vol 47. issue 9. 2009-12-22. PMID:19957883. |
protective role of sertraline against 3-nitropropionic acid-induced cognitive dysfunction and redox ratio in striatum, cortex and hippocampus of rat brain. |
2009-12-22 |
2023-08-12 |
human |
| Peter Meerlo, Ralph E Mistlberger, Barry L Jacobs, H Craig Heller, Dennis McGint. New neurons in the adult brain: the role of sleep and consequences of sleep loss. Sleep medicine reviews. vol 13. issue 3. 2009-11-17. PMID:18848476. |
these effects of sleep loss may endanger hippocampal integrity, thereby leading to cognitive dysfunction and contributing to the development of mood disorders. |
2009-11-17 |
2023-08-12 |
rat |
| Katsuhiko Maruichi, Satoshi Kuroda, Yasuhiro Chiba, Masaaki Hokari, Hideo Shichinohe, Kazutoshi Hida, Yoshinobu Iwasak. Graded model of diffuse axonal injury for studying head injury-induced cognitive dysfunction in rats. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 29. issue 2. 2009-07-17. PMID:18702633. |
hippocampal damage was much less pronounced and was not linked to cognitive dysfunction. |
2009-07-17 |
2023-08-12 |
rat |
| Liang Song, Jianbin Zheng, Hui Li, Ning Jia, Zhirong Suo, Qing Cai, Zhuanli Bai, Daxin Cheng, Zhongliang Zh. Prenatal stress causes oxidative damage to mitochondrial DNA in hippocampus of offspring rats. Neurochemical research. vol 34. issue 4. 2009-06-03. PMID:18802752. |
in our previous studies, we showed that prenatal stress (pns) preferentially caused cognitive dysfunction and increased ros in the hippocampus of female offspring rats. |
2009-06-03 |
2023-08-12 |
rat |
| Akvile Norkute, Andrea Hieble, Alena Braun, Sonja Johann, Tim Clarner, Werner Baumgartner, Cordian Beyer, Markus Kip. Cuprizone treatment induces demyelination and astrocytosis in the mouse hippocampus. Journal of neuroscience research. vol 87. issue 6. 2009-05-12. PMID:19021291. |
the degree of hippocampus lesions in ms strongly correlates with progression of cognitive dysfunction. |
2009-05-12 |
2023-08-12 |
mouse |
| Puneet Kumar, Anil Kuma. Neuroprotective effect of cyclosporine and FK506 against 3-nitropropionic acid induced cognitive dysfunction and glutathione redox in rat: possible role of nitric oxide. Neuroscience research. vol 63. issue 4. 2009-05-04. PMID:19367792. |
therefore, present study was conducted to explore their therapeutic potential against 3-nitropropionic acid induced cognitive dysfunctions and biochemical alterations in striatum, cortex and hippocampal regions of brain. |
2009-05-04 |
2023-08-12 |
rat |