| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Z Yang, M Li, X Hu, B Xiang, W Deng, Q Wang, Y Wang, L Zhao, X Ma, P C Sham, G Northoff, T L. Rare damaging variants in DNA repair and cell cycle pathways are associated with hippocampal and cognitive dysfunction: a combined genetic imaging study in first-episode treatment-naive patients with schizophrenia. Translational psychiatry. vol 7. issue 2. 2017-11-16. PMID:28195569. |
rare damaging variants in dna repair and cell cycle pathways are associated with hippocampal and cognitive dysfunction: a combined genetic imaging study in first-episode treatment-naive patients with schizophrenia. |
2017-11-16 |
2023-08-13 |
Not clear |
| Rui Wang, Yu Zhang, Jianguo Li, Ce Zhan. Resveratrol ameliorates spatial learning memory impairment induced by Aβ Neuroscience. vol 344. 2017-11-09. PMID:27600946. |
however, whether resveratrol can alleviate aβ-induced cognitive dysfunction, whether sirt1 expression and creb phosphorylation in the hippocampus are affected by aβ, and whether resveratrol influences these effects remain unknown. |
2017-11-09 |
2023-08-13 |
rat |
| Jing Cheng, Xiaoqing Liu, Longhui Cao, Tianhua Zhang, Huiting Li, Wenqian Li. Neo-adjuvant chemotherapy with cisplatin induces low expression of NMDA receptors and postoperative cognitive impairment. Neuroscience letters. vol 637. 2017-10-31. PMID:27845242. |
these results suggest that neo-adjuvant chemotherapy with cisplatin exacerbate the postoperative cognitive dysfunction in rats, and this may be caused by a lower expression of nmda receptors in the hippocampus. |
2017-10-31 |
2023-08-13 |
rat |
| Sehee Kim, Chanyang Kim, Seungjoon Par. Ghrelin gene products rescue cultured adult rat hippocampal neural stem cells from high glucose insult. Journal of molecular endocrinology. vol 57. issue 3. 2017-10-26. PMID:27530317. |
adult hippocampal neurogenesis is decreased in type 2 diabetes, and this impairment appears to be important in cognitive dysfunction. |
2017-10-26 |
2023-08-13 |
rat |
| Amanda Brondani Mucellini, Natasha Kim de Oliveira da Fonseca, Gisele Gus Manfro, Patrícia Pelufo Silveir. Hippocampal insulin resistance and altered food decision-making as players on obesity risk. Neuroscience and biobehavioral reviews. vol 77. 2017-10-26. PMID:28342765. |
insulin also has been linked to brain functions such as feeding behavior and the imbalance of its mechanism of action on hippocampus is being related to cognitive dysfunction. |
2017-10-26 |
2023-08-13 |
Not clear |
| Vineet Mehta, Arun Parashar, Arun Sharma, Tiratha Raj Singh, Malairaman Udayaban. Quercetin ameliorates chronic unpredicted stress-mediated memory dysfunction in male Swiss albino mice by attenuating insulin resistance and elevating hippocampal GLUT4 levels independent of insulin receptor expression. Hormones and behavior. vol 89. 2017-09-04. PMID:28025042. |
cus induced significant cognitive dysfunction (nor and mwm) and severely damaged hippocampal neurons, especially in the ca3 region. |
2017-09-04 |
2023-08-13 |
mouse |
| Vineet Mehta, Arun Parashar, Arun Sharma, Tiratha Raj Singh, Malairaman Udayaban. Quercetin ameliorates chronic unpredicted stress-mediated memory dysfunction in male Swiss albino mice by attenuating insulin resistance and elevating hippocampal GLUT4 levels independent of insulin receptor expression. Hormones and behavior. vol 89. 2017-09-04. PMID:28025042. |
these results suggest that intact insulin functioning in the hippocampus is essential for cognitive functions and quercetin improves cus-mediated cognitive dysfunction by modulating hippocampal insulin signaling. |
2017-09-04 |
2023-08-13 |
mouse |
| Vera Dinkelacker, Xu Xin, Michel Baulac, Séverine Samson, Sophie Dupon. Interictal epileptic discharge correlates with global and frontal cognitive dysfunction in temporal lobe epilepsy. Epilepsy & behavior : E&B. vol 62. 2017-09-01. PMID:27494355. |
temporal lobe epilepsy (tle) with hippocampal sclerosis has widespread effects on structural and functional connectivity and often entails cognitive dysfunction. |
2017-09-01 |
2023-08-13 |
Not clear |
| Xia Tian, Yanlin Liu, Guangwei Ren, Ling Yin, Xiaoyan Liang, Tao Geng, Heqin Dang, Rufeng A. Resveratrol limits diabetes-associated cognitive decline in rats by preventing oxidative stress and inflammation and modulating hippocampal structural synaptic plasticity. Brain research. vol 1650. 2017-08-21. PMID:27566063. |
therefore, we tested its influence against cognitive dysfunction as well as on hippocampal structural synaptic plasticity in streptozotocin-induced diabetic rats. |
2017-08-21 |
2023-08-13 |
rat |
| Santiago Hem, Romina Albite, Monica Loresi, Jorge Rasmussen, Pablo Ajler, Claudio Yampolsky, Joseph D Chabot, Peter C Gerszten, Ezequiel Goldschmid. Pathological changes of the hippocampus and cognitive dysfunction following frontal lobe surgery in a rat model. Acta neurochirurgica. vol 158. issue 11. 2017-07-24. PMID:27631973. |
pathological changes of the hippocampus and cognitive dysfunction following frontal lobe surgery in a rat model. |
2017-07-24 |
2023-08-13 |
rat |
| Santiago Hem, Romina Albite, Monica Loresi, Jorge Rasmussen, Pablo Ajler, Claudio Yampolsky, Joseph D Chabot, Peter C Gerszten, Ezequiel Goldschmid. Pathological changes of the hippocampus and cognitive dysfunction following frontal lobe surgery in a rat model. Acta neurochirurgica. vol 158. issue 11. 2017-07-24. PMID:27631973. |
impaired hippocampal neurogenesis has been associated with cognitive dysfunction in animal models. |
2017-07-24 |
2023-08-13 |
rat |
| Xiaoni Shao, Wenjie Lu, Fabao Gao, Dandan Li, Jing Hu, Yan Li, Zeping Zuo, Hui Jie, Yinglan Zhao, Xiaobo Ce. Uric Acid Induces Cognitive Dysfunction through Hippocampal Inflammation in Rodents and Humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 43. 2017-07-14. PMID:27798180. |
uric acid induces cognitive dysfunction through hippocampal inflammation in rodents and humans. |
2017-07-14 |
2023-08-13 |
mouse |
| Xiaoni Shao, Wenjie Lu, Fabao Gao, Dandan Li, Jing Hu, Yan Li, Zeping Zuo, Hui Jie, Yinglan Zhao, Xiaobo Ce. Uric Acid Induces Cognitive Dysfunction through Hippocampal Inflammation in Rodents and Humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 43. 2017-07-14. PMID:27798180. |
additionally, c57bl/6 mice that lack tlr4 are substantially protected against ua-induced cognitive dysfunction, possibly due to a decrease in inflammatory gene expression in the hippocampus. |
2017-07-14 |
2023-08-13 |
mouse |
| Xiaoni Shao, Wenjie Lu, Fabao Gao, Dandan Li, Jing Hu, Yan Li, Zeping Zuo, Hui Jie, Yinglan Zhao, Xiaobo Ce. Uric Acid Induces Cognitive Dysfunction through Hippocampal Inflammation in Rodents and Humans. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 43. 2017-07-14. PMID:27798180. |
together, these results suggest that ua can cause hippocampal inflammation via the tlr4/nf-κb pathway, resulting in cognitive dysfunction. |
2017-07-14 |
2023-08-13 |
mouse |
| L E Gardner, J D White, M J Eimerbrink, G W Boehm, M J Chumle. Imatinib methanesulfonate reduces hyperphosphorylation of tau following repeated peripheral exposure to lipopolysaccharide. Neuroscience. vol 331. 2017-07-11. PMID:27320209. |
previous research in our lab has shown that imatinib methanesulfonate (im) blocks the peripheral production of aβ in response to lps, thereby preventing the buildup of aβ in the hippocampus, and rescuing the cognitive dysfunction that normally follows. |
2017-07-11 |
2023-08-13 |
mouse |
| Ke Pan, Xiaojun Li, Yan Chen, Dan Zhu, Yuping Li, Guocai Tao, Zhiyi Zu. Deferoxamine pre-treatment protects against postoperative cognitive dysfunction of aged rats by depressing microglial activation via ameliorating iron accumulation in hippocampus. Neuropharmacology. vol 111. 2017-07-11. PMID:27608977. |
deferoxamine pre-treatment protects against postoperative cognitive dysfunction of aged rats by depressing microglial activation via ameliorating iron accumulation in hippocampus. |
2017-07-11 |
2023-08-13 |
rat |
| Zhuo Fu, Jing Wu, Tanseli Nesil, Ming D Li, Kevin W Aylor, Zhenqi Li. Long-term high-fat diet induces hippocampal microvascular insulin resistance and cognitive dysfunction. American journal of physiology. Endocrinology and metabolism. vol 312. issue 2. 2017-06-26. PMID:27899343. |
long-term high-fat diet induces hippocampal microvascular insulin resistance and cognitive dysfunction. |
2017-06-26 |
2023-08-13 |
rat |
| Miklós Sárvári, Imre Kalló, Erik Hrabovszky, Norbert Solymosi, Zsolt Liposit. Ovariectomy Alters Gene Expression of the Hippocampal Formation in Middle-Aged Rats. Endocrinology. vol 158. issue 1. 2017-06-23. PMID:27805868. |
the findings indicate that surgical gonadectomy carried out at middle-age robustly changes the hippocampal transcriptome that alters neurogenesis, synaptic plasticity, immune modulation, causing cognitive dysfunctions. |
2017-06-23 |
2023-08-13 |
rat |
| Bing Han, Jin-Hua Wang, Yuan Geng, Li Shen, Hua-Long Wang, Yan-Yong Wang, Ming-Wei Wan. Chronic Stress Contributes to Cognitive Dysfunction and Hippocampal Metabolic Abnormalities in APP/PS1 Mice. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. vol 41. issue 5. 2017-06-23. PMID:28365686. |
chronic stress contributes to cognitive dysfunction and hippocampal metabolic abnormalities in app/ps1 mice. |
2017-06-23 |
2023-08-13 |
mouse |
| Ya-Nan Li, Qi Zhang, Chun-Ping Yin, Yang-Yang Guo, Shu-Ping Huo, Liang Wang, Qiu-Jun Wan. Effects of nimodipine on postoperative delirium in elderly under general anesthesia: A prospective, randomized, controlled clinical trial. Medicine. vol 96. issue 19. 2017-06-12. PMID:28489775. |
nimodipine is a clinical commonly used calcium antagonistscan lowering the apoptosis rate of hippocampal neuron to reduce the incidence of postoperative cognitive dysfunction (pocd). |
2017-06-12 |
2023-08-13 |
Not clear |