| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lin Wu, Dandan Guo, Qi Liu, Fei Gao, Xiaochen Wang, Xueying Song, Fuwu Wang, Ren-Zhi Zha. Abnormal Development of Dendrites in Adult-Born Rat Hippocampal Granule Cells Induced by Cyclophosphamide. Frontiers in cellular neuroscience. vol 11. 2020-09-30. PMID:28680394. |
as abnormalities in adult hippocampal neurogenesis may serve as substrate for cognitive dysfunction, the present study examines the effect of cyclophosphamide (cpp), a widely prescribed chemotherapeutic agent, on dendritic development of adult-born hippocampal granule cells in the rat. |
2020-09-30 |
2023-08-13 |
rat |
| Pei-Pei Feng, Pu Deng, Li-Hua Liu, Qi Ai, Jie Yin, Zhe Liu, Gai-Mei Wan. Electroacupuncture Alleviates Postoperative Cognitive Dysfunction in Aged Rats by Inhibiting Hippocampal Neuroinflammation Activated via Microglia/TLRs Pathway. Evidence-based complementary and alternative medicine : eCAM. vol 2017. 2020-09-30. PMID:28684969. |
electroacupuncture alleviates postoperative cognitive dysfunction in aged rats by inhibiting hippocampal neuroinflammation activated via microglia/tlrs pathway. |
2020-09-30 |
2023-08-13 |
rat |
| Pei-Pei Feng, Pu Deng, Li-Hua Liu, Qi Ai, Jie Yin, Zhe Liu, Gai-Mei Wan. Electroacupuncture Alleviates Postoperative Cognitive Dysfunction in Aged Rats by Inhibiting Hippocampal Neuroinflammation Activated via Microglia/TLRs Pathway. Evidence-based complementary and alternative medicine : eCAM. vol 2017. 2020-09-30. PMID:28684969. |
the aim of this study was to examine whether ea improves cognitive dysfunction caused by surgery and to investigate the pathological mechanism of tlr2 and tlr4 in the hippocampus of aged rats. |
2020-09-30 |
2023-08-13 |
rat |
| Chunfang Yi, Zhiyun Fu, Xiaofeng Lu. Dexmedetomidine on autophagy of hippocampal neurons in aged rats under sevoflurane anesthesia. Experimental and therapeutic medicine. vol 16. issue 2. 2020-09-30. PMID:30112038. |
effects of dexmedetomidine on autophagy of hippocampal neurons and cognitive dysfunction in aged rats under sevoflurane anesthesia were investigated. |
2020-09-30 |
2023-08-13 |
rat |
| Bao-Liang Zhang, Yue-Shan Fan, Ji-Wei Wang, Zi-Wei Zhou, Yin-Gang Wu, Meng-Chen Yang, Dong-Dong Sun, Jian-Ning Zhan. Cognitive impairment after traumatic brain injury is associated with reduced long-term depression of excitatory postsynaptic potential in the rat hippocampal dentate gyrus. Neural regeneration research. vol 13. issue 10. 2020-09-30. PMID:30136690. |
hippocampal excitability is strongly correlated with cognitive dysfunction and remote symptomatic epilepsy. |
2020-09-30 |
2023-08-13 |
rat |
| Li-Li Li, Mei-Fang Jin, Hong N. Zinc/CaMK II Associated-Mitophagy Signaling Contributed to Hippocampal Mossy Fiber Sprouting and Cognitive Deficits Following Neonatal Seizures and Its Regulation by Chronic Leptin Treatment. Frontiers in neurology. vol 9. 2020-09-30. PMID:30319532. |
flurothyl-induced seizures (rs group) significantly down-regulated mitophagy markers pink, drp1, phb, and memory marker camk ii alpha while up-regulating zinc transporters znt3, znt4, zip7, and autophagy execution molecular cathepsin-e, which were paralleled with hippocampal aberrant mossy fiber sprouting and cognitive dysfunction. |
2020-09-30 |
2023-08-13 |
rat |
| Tsuyoshi Hashizume, Bo-Kyung Son, Sakiko Taniguchi, Koichi Ito, Yoshihiro Noda, Tamao Endo, Michiko Nanao-Hamai, Sumito Ogawa, Masahiro Akishit. Establishment of Novel Murine Model showing Vascular Inflammation-derived Cognitive Dysfunction. Scientific reports. vol 9. issue 1. 2020-09-30. PMID:30858535. |
iba1/mhcii-double-positive microglia activation was also seen in the hippocampus, suggesting that vascular inflammation drives neuroinflammation and subsequent cognitive dysfunction. |
2020-09-30 |
2023-08-13 |
mouse |
| Man-Man Zong, Zhi-Qiang Zhou, Mu-Huo Ji, Min Jia, Hui Tang, Jian-Jun Yan. Activation of β2-Adrenoceptor Attenuates Sepsis-Induced Hippocampus-Dependent Cognitive Impairments by Reversing Neuroinflammation and Synaptic Abnormalities. Frontiers in cellular neuroscience. vol 13. 2020-09-30. PMID:31354429. |
sepsis-associated encephalopathy induces cognitive dysfunction via mechanisms that commonly involve neuroinflammation and synaptic plasticity impairment of the hippocampus. |
2020-09-30 |
2023-08-13 |
mouse |
| Qingxia Kong, Xia Min, Ran Sun, Jianying Gao, Ruqing Liang, Lei Li, Xu Ch. Effects of pharmacological treatments on hippocampal NCAM1 and ERK2 expression in epileptic rats with cognitive dysfunction. Oncology letters. vol 12. issue 3. 2020-09-29. PMID:27588125. |
effects of pharmacological treatments on hippocampal ncam1 and erk2 expression in epileptic rats with cognitive dysfunction. |
2020-09-29 |
2023-08-13 |
rat |
| Qingxia Kong, Xia Min, Ran Sun, Jianying Gao, Ruqing Liang, Lei Li, Xu Ch. Effects of pharmacological treatments on hippocampal NCAM1 and ERK2 expression in epileptic rats with cognitive dysfunction. Oncology letters. vol 12. issue 3. 2020-09-29. PMID:27588125. |
the present study aimed to investigate the effects of various pharmacological agents on the hippocampal expression of neural cell adhesion molecule 1 (ncam1) and extracellular signal-regulated kinase 2 (erk2) in epileptic rats with cognitive dysfunction. |
2020-09-29 |
2023-08-13 |
rat |
| Sahar Fanoudi, Mahmoud Hosseini, Mohaddeseh Sadat Alavi, Mohammad Taher Boroushaki, Azar Hosseini, Hamid R Sadeghni. Everolimus, a mammalian target of rapamycin inhibitor, ameliorated streptozotocin-induced learning and memory deficits via neurochemical alterations in male rats. EXCLI journal. vol 17. 2020-09-29. PMID:30564080. |
chronic administration (1 and 5 mg/kg for 21 days from the day of surgery and icv-stz infusion) or acute injection (5 mg/kg for 7 days after establishment of cognitive impairment) of evr significantly attenuated cognitive dysfunction, neuronal loss, oxidative stress and ache activity in the hippocampus of stz-ad rats. |
2020-09-29 |
2023-08-13 |
rat |
| Si-Min Chen, Yi-Li Yi, Dan Zeng, Yi-Yun Tang, Xuan Kang, Ping Zhang, Wei Zou, Xiao-Qing Tan. Hydrogen Sulfide Attenuates β2-Microglobulin-Induced Cognitive Dysfunction: Involving Recovery of Hippocampal Autophagic Flux. Frontiers in behavioral neuroscience. vol 13. 2020-09-29. PMID:31708756. |
hydrogen sulfide attenuates β2-microglobulin-induced cognitive dysfunction: involving recovery of hippocampal autophagic flux. |
2020-09-29 |
2023-08-13 |
Not clear |
| Guowen Hu, Yuguo Xia, Juntao Zhang, Yu Chen, Ji Yuan, Xin Niu, Bizeng Zhao, Qing Li, Yang Wang, Zhifeng Den. ESC-sEVs Rejuvenate Senescent Hippocampal NSCs by Activating Lysosomes to Improve Cognitive Dysfunction in Vascular Dementia. Advanced science (Weinheim, Baden-Wurttemberg, Germany). vol 7. issue 10. 2020-09-28. PMID:32440476. |
esc-sevs rejuvenate senescent hippocampal nscs by activating lysosomes to improve cognitive dysfunction in vascular dementia. |
2020-09-28 |
2023-08-13 |
rat |
| Marek Sąsiadek, Marcin Hartel, Małgorzata Siger, Katarzyna Katulska, Agata Majos, Ewa Kluczewska, Halina Bartosik-Psujek, Alina Kułakowska, Agnieszka Słowik, Barbara Steinborn, Monika Adamczyk-Sowa, Alicja Kalinowska, Ewa Krzystanek, Robert Bonek, Zbigniew Serafin, Jarosław Sławek, Przemysław Nowacki, Adam Stępień, Sergiusz Jóżwiak, Konrad Rejdak, Krzysztof Selmaj, Jerzy Waleck. Recommendations of the Polish Medical Society of Radiology and the Polish Society of Neurology for the routinely used magnetic resonance imaging protocol in patients with multiple sclerosis. Polish journal of radiology. vol 85. 2020-09-28. PMID:32612727. |
it is also the best tool to assess brain atrophy in patients with ms in terms of grey matter volume and white matter volume as well as local atrophy (by measuring the volume of thalamus, corpus callosum, subcortical nuclei, hippocampus) as parameters that correlate with disability progression and cognitive dysfunctions. |
2020-09-28 |
2023-08-13 |
human |
| Zhiqiang Yu, Jinxin Wang, Peijun Zhang, Jianbo Wang, Jian Cui, Haiyun Wan. Enriched environment improves sevoflurane-induced cognitive impairment during late-pregnancy via hippocampal histone acetylation. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 53. issue 10. 2020-09-28. PMID:32813852. |
ee alleviated sevoflurane-induced cognitive dysfunction and increased hippocampal bdnf, ac-h3, and ac-h4. |
2020-09-28 |
2023-08-13 |
rat |
| Yang Wu, Juan Dou, Xing Wan, Yan Leng, Xuke Liu, Lili Chen, Qianni Shen, Bo Zhao, Qingtao Meng, Jiabao Ho. Histone Deacetylase Inhibitor MS-275 Alleviates Postoperative Cognitive Dysfunction in Rats by Inhibiting Hippocampal Neuroinflammation. Neuroscience. vol 417. 2020-09-24. PMID:31430527. |
histone deacetylase inhibitor ms-275 alleviates postoperative cognitive dysfunction in rats by inhibiting hippocampal neuroinflammation. |
2020-09-24 |
2023-08-13 |
rat |
| Yang Wu, Juan Dou, Xing Wan, Yan Leng, Xuke Liu, Lili Chen, Qianni Shen, Bo Zhao, Qingtao Meng, Jiabao Ho. Histone Deacetylase Inhibitor MS-275 Alleviates Postoperative Cognitive Dysfunction in Rats by Inhibiting Hippocampal Neuroinflammation. Neuroscience. vol 417. 2020-09-24. PMID:31430527. |
neuroinflammation in the hippocampus plays essential roles in postoperative cognitive dysfunction (pocd). |
2020-09-24 |
2023-08-13 |
rat |
| Yang Wu, Juan Dou, Xing Wan, Yan Leng, Xuke Liu, Lili Chen, Qianni Shen, Bo Zhao, Qingtao Meng, Jiabao Ho. Histone Deacetylase Inhibitor MS-275 Alleviates Postoperative Cognitive Dysfunction in Rats by Inhibiting Hippocampal Neuroinflammation. Neuroscience. vol 417. 2020-09-24. PMID:31430527. |
these results suggest that ms-275 alleviates postoperative cognitive dysfunction by reducing neuroinflammation in the hippocampus of rats via hdac inhibition. |
2020-09-24 |
2023-08-13 |
rat |
| Ziyi Wang, Yuying Lin, Weitang Liu, Ping Kuang, Wenwen Lao, Yonghua Ji, Hongyan Zh. Voltage-Gated Sodium Channels Are Involved in Cognitive Impairments in Parkinson's Disease- like Rats. Neuroscience. vol 418. 2020-09-24. PMID:31473280. |
the abnormal synaptic plasticity in the hippocampus is suggested to be associated with cognitive dysfunction in pd. |
2020-09-24 |
2023-08-13 |
rat |
| Jeremy D Hill, Viviana Zuluaga-Ramirez, Sachin Gajghate, Malika Winfield, Yuri Persidsk. Chronic Intrahippocampal Infusion of HIV-1 Neurotoxic Proteins: A Novel Mouse Model of HIV-1 Associated Inflammation and Neural Stem Cell Dysfunction. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. vol 14. issue 3. 2020-09-18. PMID:30905008. |
these data suggest that chronic administration induces a prolonged inflammatory state within the hippocampus that negatively affects nsc survival potentially leading to cognitive dysfunction. |
2020-09-18 |
2023-08-13 |
mouse |