| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stephen A Goutman, Orla Hardiman, Ammar Al-Chalabi, Adriano Chió, Masha G Savelieff, Matthew C Kiernan, Eva L Feldma. Emerging insights into the complex genetics and pathophysiology of amyotrophic lateral sclerosis. The Lancet. Neurology. 2022-03-25. PMID:35334234. |
the discovery of genes associated with amyotrophic lateral sclerosis, commencing with sod1 in 1993, started fairly gradually. |
2022-03-25 |
2023-08-13 |
Not clear |
| Michiko Tajiri, Hiroto Aoki, Atsuko Shintani, Kaori Sue, Satoko Akashi, Yoshiaki Furukaw. Metal distribution in Cu/Zn-superoxide dismutase revealed by native mass spectrometry. Free radical biology & medicine. 2022-03-22. PMID:35314356. |
a failure of correct metallation in sod1 will also be discussed in relation to amyotrophic lateral sclerosis. |
2022-03-22 |
2023-08-13 |
Not clear |
| Dillon Shapiro, Ryan Massopust, Thomas Taetzsch, Gregorio Valde. Argonaute 2 is lost from neuromuscular junctions affected with amyotrophic lateral sclerosis in SOD1 Scientific reports. vol 12. issue 1. 2022-03-18. PMID:35301367. |
argonaute 2 is lost from neuromuscular junctions affected with amyotrophic lateral sclerosis in sod1 mirnas are necessary for neuromuscular junction (nmj) health; however, little is known about the proteins required for their activity in this regard. |
2022-03-18 |
2023-08-13 |
Not clear |
| Duygu Aydemir, Anjum Naeem Malik, Ibrahim Kulac, Ayse Nazli Basak, Ismail Lazoglu, Nuriye Nuray Ulus. Impact of the Amyotrophic Lateral Sclerosis Disease on the Biomechanical Properties and Oxidative Stress Metabolism of the Lung Tissue Correlated With the Human Mutant SOD1 Frontiers in bioengineering and biotechnology. vol 10. 2022-03-14. PMID:35284425. |
impact of the amyotrophic lateral sclerosis disease on the biomechanical properties and oxidative stress metabolism of the lung tissue correlated with the human mutant sod1 amyotrophic lateral sclerosis (als) is the most common motor neuron disease, and als incidence is increasing worldwide. |
2022-03-14 |
2023-08-13 |
human |
| Aidan Zhang, Knut Teigen, Valentina L Kouznetsova, Igor F Tsigeln. Modeling of mutant superoxide dismutase 1 octamers with cross-linked disulfide bonds. Journal of molecular modeling. vol 28. issue 4. 2022-03-13. PMID:35279789. |
this cyclic structure may allow sod1 to form ion channels on membranes such as the mitochondrial membrane, causing imbalances in the concentration of intracellular ions as a potential mechanism for the progressive neuron death involved in amyotrophic lateral sclerosis (als). |
2022-03-13 |
2023-08-13 |
Not clear |
| Laura M Cox, Narghes Calcagno, Christian Gauthier, Charlotte Madore, Oleg Butovsky, Howard L Weine. The microbiota restrains neurodegenerative microglia in a model of amyotrophic lateral sclerosis. Microbiome. vol 10. issue 1. 2022-03-11. PMID:35272713. |
while antibiotics improve models of alzheimer's disease, parkinson's disease, multiple sclerosis, and the c9orf72 model of amyotrophic lateral sclerosis (als), antibiotics worsen disease progression the in sod1 |
2022-03-11 |
2023-08-13 |
Not clear |
| Victoria M McLeod, Mathew D F Chiam, Nirma D Perera, Chew L Lau, Wah Chin Boon, Bradley J Turne. Mapping Motor Neuron Vulnerability in the Neuraxis of Male SOD1 Frontiers in endocrinology. vol 13. 2022-03-11. PMID:35273564. |
mapping motor neuron vulnerability in the neuraxis of male sod1 sex steroid hormones have been implicated as disease modifiers in the neurodegenerative disorder amyotrophic lateral sclerosis (als). |
2022-03-11 |
2023-08-13 |
Not clear |
| Ekene Anakor, Vanessa Milla, Owen Connolly, Cecile Martinat, Pierre Francois Pradat, Julie Dumonceaux, William Duddy, Stephanie Dugue. The Neurotoxicity of Vesicles Secreted by ALS Patient Myotubes Is Specific to Exosome-Like and Not Larger Subtypes. Cells. vol 11. issue 5. 2022-03-10. PMID:35269468. |
they are increasingly investigated in amyotrophic lateral sclerosis, the most common form of motor neurone disease, as transporters of misfolded proteins including sod1, fus, tdp43, or other neurotoxic elements, such as the dipeptide repeats resulting from |
2022-03-10 |
2023-08-13 |
Not clear |
| Pegah Masrori, Simona Ospitalieri, Karin Forsberg, Thomas G Moens, Koen Poesen, Valerie Race, Thomas Brännström, Peter M Andersen, Dietmar R Thal, Philip Van Damm. Respiratory onset of amyotrophic lateral sclerosis in a pregnant woman with a novel SOD1 mutation. European journal of neurology. vol 29. issue 4. 2022-03-07. PMID:35253968. |
respiratory onset of amyotrophic lateral sclerosis in a pregnant woman with a novel sod1 mutation. |
2022-03-07 |
2023-08-13 |
Not clear |
| Michael MacLean, Raquel López-Díez, Carolina Vasquez, Paul F Gugger, Ann Marie Schmid. Neuronal-glial communication perturbations in murine SOD1 Communications biology. vol 5. issue 1. 2022-03-01. PMID:35228715. |
neuronal-glial communication perturbations in murine sod1 amyotrophic lateral sclerosis (als) is an incurable disease characterized by proteinaceous aggregate accumulation and neuroinflammation culminating in rapidly progressive lower and upper motor neuron death. |
2022-03-01 |
2023-08-13 |
Not clear |
| Joyce Xu, Xiaoyang Su, Stephen K Burley, X F Steven Zhen. Nuclear SOD1 in Growth Control, Oxidative Stress Response, Amyotrophic Lateral Sclerosis, and Cancer. Antioxidants (Basel, Switzerland). vol 11. issue 2. 2022-02-25. PMID:35204309. |
nuclear sod1 in growth control, oxidative stress response, amyotrophic lateral sclerosis, and cancer. |
2022-02-25 |
2023-08-13 |
Not clear |
| Joyce Xu, Xiaoyang Su, Stephen K Burley, X F Steven Zhen. Nuclear SOD1 in Growth Control, Oxidative Stress Response, Amyotrophic Lateral Sclerosis, and Cancer. Antioxidants (Basel, Switzerland). vol 11. issue 2. 2022-02-25. PMID:35204309. |
sod1 dysregulation has been associated with many diseases, including amyotrophic lateral sclerosis (als), cancer, accelerated aging, and age-related diseases. |
2022-02-25 |
2023-08-13 |
Not clear |
| Xiaojiao Xu, Jingjing Zhang, Song Li, Murad Al-Nusaif, Qinming Zhou, Sheng Chen, Weidong L. Bone Marrow Stromal Cell Antigen 2: Is a Potential Neuroinflammation Biomarker of SOD1 Frontiers in neuroscience. vol 15. 2022-02-24. PMID:35197819. |
bone marrow stromal cell antigen 2: is a potential neuroinflammation biomarker of sod1 neuroinflammation has long been thought to be associated with amyotrophic lateral sclerosis (als) development and progression. |
2022-02-24 |
2023-08-13 |
Not clear |
| Jialing Peng, Jingrui Pan, Jingjing Mo, Ying Pen. MPO/HOCl Facilitates Apoptosis and Ferroptosis in the SOD1 Oxidative medicine and cellular longevity. vol 2022. 2022-02-18. PMID:35178161. |
mpo/hocl facilitates apoptosis and ferroptosis in the sod1 oxidative stress and reactive oxygen species (ros) are important in the pathogenesis of amyotrophic lateral sclerosis (als). |
2022-02-18 |
2023-08-13 |
Not clear |
| Hui Xu, Congcong Jia, Cheng Cheng, Haifeng Wu, Huaibin Cai, Weidong L. Activation of autophagy attenuates motor deficits and extends lifespan in a C. elegans model of ALS. Free radical biology & medicine. 2022-02-03. PMID:35114355. |
mutations in cu/zn-superoxide dismutase 1 (sod1) are linked to amyotrophic lateral sclerosis (als). |
2022-02-03 |
2023-08-13 |
human |
| Héctor M Estévez-Silva, Tomás Mediavilla, Bruno Lima Giacobbo, Xijia Liu, Fahad R Sultan, Daniel J Marcellin. Pridopidine modifies disease phenotype in a SOD1 mouse model of Amyotrophic Lateral Sclerosis. The European journal of neuroscience. 2022-01-26. PMID:35080077. |
pridopidine modifies disease phenotype in a sod1 mouse model of amyotrophic lateral sclerosis. |
2022-01-26 |
2023-08-13 |
mouse |
| b' Antonio Canosa, Andrea Calvo, Cristina Moglia, Rosario Vasta, Francesca Palumbo, Luca Solero, Francesca Di Pede, Sara Cabras, Vincenzo Arena, Grazia Zocco, Federico Casale, Maura Brunetti, Luca Sbaiz, Salvatore Gallone, Maurizio Grassano, Umberto Manera, Marco Pagani, Adriano Chi\\xc3\\xb. Amyotrophic lateral sclerosis with SOD1 mutations shows distinct brain metabolic changes. European journal of nuclear medicine and molecular imaging. 2022-01-25. PMID:35076740.' |
amyotrophic lateral sclerosis with sod1 mutations shows distinct brain metabolic changes. |
2022-01-25 |
2023-08-13 |
Not clear |
| Maria Garofalo, Cecilia Pandini, Matteo Bordoni, Emanuela Jacchetti, Luca Diamanti, Stephana Carelli, Manuela Teresa Raimondi, Daisy Sproviero, Valeria Crippa, Serena Carra, Angelo Poletti, Orietta Pansarasa, Stella Gagliardi, Cristina Cered. RNA Molecular Signature Profiling in PBMCs of Sporadic ALS Patients: HSP70 Overexpression Is Associated with Nuclear SOD1. Cells. vol 11. issue 2. 2022-01-21. PMID:35053410. |
superoxide dismutase 1 (sod1) is one of the causative genes associated with amyotrophic lateral sclerosis (als), a neurodegenerative disorder. |
2022-01-21 |
2023-08-13 |
Not clear |
| Jackson E Powell, Colin K W Lim, Ramya Krishnan, Tristan X McCallister, Christian Saporito-Magriña, Maria A Zeballos, Garrett D McPheron, Thomas Ga. Targeted gene silencing in the nervous system with CRISPR-Cas13. Science advances. vol 8. issue 3. 2022-01-19. PMID:35044815. |
intrathecally delivering an adeno-associated virus vector encoding an rfxcas13d variant programmed to target superoxide dismutase 1 (sod1), a protein whose mutation can cause amyotrophic lateral sclerosis, reduced sod1 mrna and protein in the spinal cord by >50% and improved outcomes in a mouse model of the disorder. |
2022-01-19 |
2023-08-13 |
mouse |
| Mariusz Berdyński, Przemysław Miszta, Krzysztof Safranow, Peter M Andersen, Mitsuya Morita, Sławomir Filipek, Cezary Żekanowski, Magdalena Kuźma-Kozakiewic. SOD1 mutations associated with amyotrophic lateral sclerosis analysis of variant severity. Scientific reports. vol 12. issue 1. 2022-01-08. PMID:34996976. |
sod1 mutations associated with amyotrophic lateral sclerosis analysis of variant severity. |
2022-01-08 |
2023-08-13 |
Not clear |