| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Antonio Orlacchio, Toshitaka Kawarai, Eleonora Paciotti, Alessandro Stefani, Aldo Orlacchio, Sandro Sorbi, Peter H St George-Hyslop, Giorgio Bernard. Association study of the 5-hydroxytryptamine(6) receptor gene in Alzheimer's disease. Neuroscience letters. vol 325. issue 1. 2002-07-10. PMID:12023056. |
serotonergic (5-hydroxytryptamine; 5-ht) transmission has been implicated in the pathogenesis of alzheimer's disease (ad). |
2002-07-10 |
2023-08-12 |
Not clear |
| B Lack, S Daya, T Nyokon. Interaction of serotonin and melatonin with sodium, potassium, calcium, lithium and aluminium. Journal of pineal research. vol 31. issue 2. 2002-03-04. PMID:11555164. |
the binding of serotonin to lithium could provide an explanation for the therapeutic effects of lithium in depression treatment, whereas the binding of aluminium by melatonin could provide insight into the role of this element in the aetiology of alzheimer's disease. |
2002-03-04 |
2023-08-12 |
Not clear |
| B Nacmias, A Tedde, P Forleo, S Piacentini, B M Guarnieri, A Bartoli, L Ortenzi, C Petruzzi, A Serio, G Marcon, S Sorb. Association between 5-HT(2A) receptor polymorphism and psychotic symptoms in Alzheimer's disease. Biological psychiatry. vol 50. issue 6. 2001-12-07. PMID:11566166. |
association between 5-ht(2a) receptor polymorphism and psychotic symptoms in alzheimer's disease. |
2001-12-07 |
2023-08-12 |
Not clear |
| B Nacmias, A Tedde, P Forleo, S Piacentini, B M Guarnieri, A Bartoli, L Ortenzi, C Petruzzi, A Serio, G Marcon, S Sorb. Association between 5-HT(2A) receptor polymorphism and psychotic symptoms in Alzheimer's disease. Biological psychiatry. vol 50. issue 6. 2001-12-07. PMID:11566166. |
the aim of this study is to analyze the segregation of the 102t/c polymorphism in the serotonin 2a receptor gene in patients affected by sporadic and familial alzheimer's disease (fad) with and without psychotic symptoms. |
2001-12-07 |
2023-08-12 |
Not clear |
| A Gjedd. [Receptor mapping in living human beings by means of positron emission tomography]. Ugeskrift for laeger. vol 163. issue 38. 2001-10-25. PMID:11577527. |
pet has revealed loss of dopaminergic terminals and dopamine synthetic capacity in parkinson's disease, mptp intoxication, and lesch-nyhan's syndrome; release of dopamine after administration of cocaine and amphetamine, and in motor activity and cognition; increased synaptic dopamine and release of dopamine, and the 70-90% neuroleptic occupancy of dopamine receptors in the striatum, in patients with schizophrenia; loss of muscarinic and nicotinergic receptors in alzheimer's disease, and benzodiazepine and opiate receptors in stroke, epilepsy, and huntington's chorea; altered opiate receptors in chronic pain and drug abuse; and release of opiates in analgesia; but changes in serotonin synthesis, transport, and binding in affective or psychotic disorders remain elusive. |
2001-10-25 |
2023-08-12 |
human |
| H C Liu, C J Hong, C Y Liu, K N Lin, S J Tsai, T Y Liu, C W Chi, P N Wan. Association analysis of the 5-HT6 receptor polymorphism C267T with depression in patients with Alzheimer's disease. Psychiatry and clinical neurosciences. vol 55. issue 4. 2001-10-04. PMID:11442897. |
a significant increase of 267c allele of the 5-ht(6) receptor gene has been reported in patients with alzheimer's disease (ad). |
2001-10-04 |
2023-08-12 |
Not clear |
| D L Sukonick, B G Pollock, R A Sweet, B H Mulsant, J Rosen, W E Klunk, K B Kastango, S T DeKosky, R E Ferrel. The 5-HTTPR*S/*L polymorphism and aggressive behavior in Alzheimer disease. Archives of neurology. vol 58. issue 9. 2001-10-04. PMID:11559314. |
aggressive behavior in alzheimer disease (ad) has been linked to dysfunction of serotonin neurotransmission. |
2001-10-04 |
2023-08-12 |
Not clear |
| J S Rubinsztein, R D Rogers, W J Riedel, M A Mehta, T W Robbins, B J Sahakia. Acute dietary tryptophan depletion impairs maintenance of "affective set" and delayed visual recognition in healthy volunteers. Psychopharmacology. vol 154. issue 3. 2001-09-20. PMID:11351939. |
altered serotonergic transmission in affective disorders and alzheimer's disease has prompted research aimed at defining the precise cognitive effects of depleting central serotonin in humans, using acute dietary tryptophan depletion. |
2001-09-20 |
2023-08-12 |
human |
| S J Tsai, C J Hong, T Y Liu, C Y Cheng, H C Li. Association study for a functional serotonin transporter gene polymorphism and late-onset Alzheimer's disease for Chinese patients. Neuropsychobiology. vol 44. issue 1. 2001-08-30. PMID:11408789. |
association study for a functional serotonin transporter gene polymorphism and late-onset alzheimer's disease for chinese patients. |
2001-08-30 |
2023-08-12 |
human |
| S J Tsai, C J Hong, T Y Liu, C Y Cheng, H C Li. Association study for a functional serotonin transporter gene polymorphism and late-onset Alzheimer's disease for Chinese patients. Neuropsychobiology. vol 44. issue 1. 2001-08-30. PMID:11408789. |
two recent studies have demonstrated an association for a deletion/insertion polymorphism within the promoter region of the serotonin transporter gene (5-httlpr), and alzheimer's disease (ad). |
2001-08-30 |
2023-08-12 |
human |
| Y C Wang, S J Tsai, T Y Liu, H C Liu, C J Hon. No association between tryptophan hydroxylase gene polymorphism and Alzheimer's disease. Neuropsychobiology. vol 43. issue 1. 2001-07-05. PMID:11150890. |
serotonergic dysfunction is implicated in alzheimer's disease (ad) on the basis of studies of serotonin and its metabolite in postmortem specimens and csf. |
2001-07-05 |
2023-08-12 |
human |
| O Spigset, C Wilhelmsson, T Mjörndal, S Eriksso. Serotonin 5-HT2A receptor binding in platelets from patients with Alzheimer's disease or vascular dementia. International psychogeriatrics. vol 12. issue 4. 2001-05-24. PMID:11263719. |
serotonin 5-ht2a receptor binding in platelets from patients with alzheimer's disease or vascular dementia. |
2001-05-24 |
2023-08-12 |
Not clear |
| R Mössner, A Schmitt, Y Syagailo, M Gerlach, P Riederer, K P Lesc. The serotonin transporter in Alzheimer's and Parkinson's disease. Journal of neural transmission. Supplementum. issue 60. 2001-04-12. PMID:11205152. |
the serotonin transporter in alzheimer's and parkinson's disease. |
2001-04-12 |
2023-08-12 |
human |
| H Rafael, R Mego, P Moromizato, M Espinoz. Omental transplantation for Alzheimer's disease. Neurology India. vol 48. issue 4. 2001-02-15. PMID:11146593. |
the acetylcholine, dopamine, serotonin and other neurotransmitters may be reduced in the subcommissural regions even in the early stages of alzheimer's disease(ad), due to hypoperfusion of the anterior perforating and anterior choroidal arteries. |
2001-02-15 |
2023-08-12 |
Not clear |
| M Hu, W Retz, M Baader, B Pesold, G Adler, F A Henn, M Rösler, J Thom. Promoter polymorphism of the 5-HT transporter and Alzheimer's disease. Neuroscience letters. vol 294. issue 1. 2000-12-22. PMID:11044587. |
promoter polymorphism of the 5-ht transporter and alzheimer's disease. |
2000-12-22 |
2023-08-12 |
Not clear |
| A M Hussain, A K Mitr. Effect of aging on tryptophan hydroxylase in rat brain: implications on serotonin level. Drug metabolism and disposition: the biological fate of chemicals. vol 28. issue 9. 2000-10-04. PMID:10950846. |
such alterations in trph activity may reduce the level of serotonin in brain, which may be linked to late-life depression and other brain disorders, such as alzheimer and parkinson diseases. |
2000-10-04 |
2023-08-12 |
rat |
| C P Chen, S L Eastwood, T Hope, B McDonald, P T Francis, M M Esir. Immunocytochemical study of the dorsal and median raphe nuclei in patients with Alzheimer's disease prospectively assessed for behavioural changes. Neuropathology and applied neurobiology. vol 26. issue 4. 2000-09-19. PMID:10931368. |
the dorsal and median raphe nuclei were examined with immunocytochemistry to display the 5-ht neurones in 16 cases of post-mortem-proven alzheimer's disease (ad) and 12 age and sex-matched controls. |
2000-09-19 |
2023-08-12 |
Not clear |
| H L Hedin, S Eriksson, C J Fowle. Rapid inhibition by sodium azide of the phosphoinositide-mediated calcium response to serotonin stimulation in human platelets: preservation in Alzheimer's disease. Biochemical and biophysical research communications. vol 274. issue 2. 2000-08-24. PMID:10913362. |
rapid inhibition by sodium azide of the phosphoinositide-mediated calcium response to serotonin stimulation in human platelets: preservation in alzheimer's disease. |
2000-08-24 |
2023-08-12 |
human |
| H L Hedin, S Eriksson, C J Fowle. Rapid inhibition by sodium azide of the phosphoinositide-mediated calcium response to serotonin stimulation in human platelets: preservation in Alzheimer's disease. Biochemical and biophysical research communications. vol 274. issue 2. 2000-08-24. PMID:10913362. |
the effect of nan(3) upon the response to serotonin, which was not blocked by either glutathione ethyl ester (gtee) or dithiothreitol (dtt), was similar in platelets obtained from patients with alzheimer's disease and from age- and gender-matched controls. |
2000-08-24 |
2023-08-12 |
human |
| H Kunugi, A Ueki, M Otsuka, K Isse, H Hirasawa, N Kato, T Nabika, S Kobayashi, S Nank. Alzheimer's disease and 5-HTTLPR polymorphism of the serotonin transporter gene: no evidence for an association. American journal of medical genetics. vol 96. issue 3. 2000-08-10. PMID:10898905. |
alzheimer's disease and 5-httlpr polymorphism of the serotonin transporter gene: no evidence for an association. |
2000-08-10 |
2023-08-12 |
Not clear |