| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Selva Rivas-Arancibia, Rosalinda Guevara-Guzmán, Yolanda López-Vidal, Erika Rodríguez-Martínez, Margarete Zanardo-Gomes, Mariana Angoa-Pérez, Rita Raisman-Vozar. Oxidative stress caused by ozone exposure induces loss of brain repair in the hippocampus of adult rats. Toxicological sciences : an official journal of the Society of Toxicology. vol 113. issue 1. 2010-02-22. PMID:19833740. |
these alterations suggest that oxidative stress caused by low doses of ozone causes dysregulation of inflammatory processes, progressive neurodegeneration, chronic loss of brain repair in the hippocampus, and brain plasticity changes in the rat analogous to those seen in alzheimer's disease. |
2010-02-22 |
2023-08-12 |
rat |
| A H Moore, M Wu, S S Shaftel, K A Graham, M K O'Banio. Sustained expression of interleukin-1beta in mouse hippocampus impairs spatial memory. Neuroscience. vol 164. issue 4. 2010-02-19. PMID:19744544. |
few studies have investigated the impact of sustained elevation of hippocampal interleukin-1beta, a pro-inflammatory cytokine upregulated during aging and alzheimer's disease, on cognition in mice. |
2010-02-19 |
2023-08-12 |
mouse |
| P Bourgeat, G Chételat, V L Villemagne, J Fripp, P Raniga, K Pike, O Acosta, C Szoeke, S Ourselin, D Ames, K A Ellis, R N Martins, C L Masters, C C Rowe, O Salvad. Beta-amyloid burden in the temporal neocortex is related to hippocampal atrophy in elderly subjects without dementia. Neurology. vol 74. issue 2. 2010-02-16. PMID:20065247. |
to investigate whether global and regional beta-amyloid (abeta) burden as measured with 11c pittsburgh compound b (pib) pet is associated with hippocampal atrophy characterized using mri in healthy controls and patients with amnestic mild cognitive impairment (amci) or alzheimer disease (ad). |
2010-02-16 |
2023-08-12 |
human |
| R R Lemos, C H Castelletti, J L Lima Filho, E T Marques, J R M Oliveir. In silico identification of new genetic variations as potential risk factors for Alzheimer's disease in a microarray-oriented simulation. Journal of molecular neuroscience : MN. vol 39. issue 1-2. 2010-02-12. PMID:19290494. |
motivated by the former interest of our group in genetic polymorphisms involved with the immune system, we selected five genes from a previous expression microarrays study of hippocampal cornu ammonis (ca1) area of alzheimer's disease subjects (ad). |
2010-02-12 |
2023-08-12 |
human |
| Robin Wolz, Paul Aljabar, Joseph V Hajnal, Alexander Hammers, Daniel Ruecker. LEAP: learning embeddings for atlas propagation. NeuroImage. vol 49. issue 2. 2010-02-12. PMID:19815080. |
we applied the proposed method to an exemplar region centered around the hippocampus from a set of 30 atlases based on images from young healthy subjects and a dataset of 796 images from elderly dementia patients and age-matched controls enrolled in the alzheimer's disease neuroimaging initiative (adni). |
2010-02-12 |
2023-08-12 |
human |
| Lei Wang, Michael P Harms, Jarrod M Staggs, Chengjie Xiong, John C Morris, John G Csernansky, James E Galvi. Donepezil treatment and changes in hippocampal structure in very mild Alzheimer disease. Archives of neurology. vol 67. issue 1. 2010-02-12. PMID:20065136. |
donepezil treatment and changes in hippocampal structure in very mild alzheimer disease. |
2010-02-12 |
2023-08-12 |
human |
| Lei Wang, Michael P Harms, Jarrod M Staggs, Chengjie Xiong, John C Morris, John G Csernansky, James E Galvi. Donepezil treatment and changes in hippocampal structure in very mild Alzheimer disease. Archives of neurology. vol 67. issue 1. 2010-02-12. PMID:20065136. |
to compare longitudinal changes in the hippocampal structure in subjects with very mild dementia of the alzheimer type (dat) treated with donepezil hydrochloride, untreated subjects with very mild dat, and controls without dementia. |
2010-02-12 |
2023-08-12 |
human |
| Ze-Qiang Qu, Yan Zhou, Yuan-Shan Zeng, Yan Li, Peter Chun. Pretreatment with Rhodiola rosea extract reduces cognitive impairment induced by intracerebroventricular streptozotocin in rats: implication of anti-oxidative and neuroprotective effects. Biomedical and environmental sciences : BES. vol 22. issue 4. 2010-02-05. PMID:19950527. |
to investigate the pretreatment effects of rhodiola rosea (r. rosea) extract on cognitive dysfunction, oxidative stress in hippocampus and hippocampal neuron injury in a rat model of alzheimer's disease (ad). |
2010-02-05 |
2023-08-12 |
rat |
| Yingxin Yu, Jue He, Yanbo Zhang, Huanmin Luo, Shenghua Zhu, Yi Yang, Tou Zhao, Jiang Wu, Yuangui Huang, Jiming Kong, Qingrong Tan, Xin-Min L. Increased hippocampal neurogenesis in the progressive stage of Alzheimer's disease phenotype in an APP/PS1 double transgenic mouse model. Hippocampus. vol 19. issue 12. 2010-01-28. PMID:19309037. |
increased hippocampal neurogenesis in the progressive stage of alzheimer's disease phenotype in an app/ps1 double transgenic mouse model. |
2010-01-28 |
2023-08-12 |
mouse |
| Steven G Potkin, Guia Guffanti, Anita Lakatos, Jessica A Turner, Frithjof Kruggel, James H Fallon, Andrew J Saykin, Alessandro Orro, Sara Lupoli, Erika Salvi, Michael Weiner, Fabio Macciard. Hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for Alzheimer's disease. PloS one. vol 4. issue 8. 2010-01-19. PMID:19668339. |
hippocampal atrophy as a quantitative trait in a genome-wide association study identifying novel susceptibility genes for alzheimer's disease. |
2010-01-19 |
2023-08-12 |
Not clear |
| Robyn A Honea, George P Thomas, Amith Harsha, Heather S Anderson, Joseph E Donnelly, William M Brooks, Jeffrey M Burn. Cardiorespiratory fitness and preserved medial temporal lobe volume in Alzheimer disease. Alzheimer disease and associated disorders. vol 23. issue 3. 2010-01-08. PMID:19812458. |
the relationship of fitness to alzheimer disease (ad)-related brain change is understudied, particularly in the hippocampus, which is disproportionately affected in early ad. |
2010-01-08 |
2023-08-12 |
Not clear |
| Maria-Angeles Arevalo, Pedro M Roldan, Pedro J Chacón, Alfredo Rodríguez-Teba. Amyloid beta serves as an NGF-like neurotrophic factor or acts as a NGF antagonist depending on its concentration. Journal of neurochemistry. vol 111. issue 6. 2010-01-08. PMID:20050289. |
amyloid beta (abeta), a pathogenic agent in alzheimer's disease (ad) is known to bind to p75(ntr), hence we studied its influence on cultured hippocampal neurons. |
2010-01-08 |
2023-08-12 |
mouse |
| Chuanming Li, Jian Zheng, Jian Wang, Li Gui, Chuan L. An fMRI stroop task study of prefrontal cortical function in normal aging, mild cognitive impairment, and Alzheimer's disease. Current Alzheimer research. vol 6. issue 6. 2010-01-05. PMID:19747163. |
severe cortex lesions in the hippocampal, parahippocampal and medial temporal lobe (mtl) of alzheimer's disease subjects have been observed by functional magnetic resonance imaging (fmri) during memory task performance. |
2010-01-05 |
2023-08-12 |
human |
| Wolfgang Lieb, Alexa S Beiser, Ramachandran S Vasan, Zaldy S Tan, Rhoda Au, Tamara B Harris, Ronenn Roubenoff, Sanford Auerbach, Charles DeCarli, Philip A Wolf, Sudha Seshadr. Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging. JAMA. vol 302. issue 23. 2010-01-05. PMID:20009056. |
the adipokine leptin facilitates long-term potentiation and synaptic plasticity in the hippocampus, promotes beta-amyloid clearance, and improves memory function in animal models of aging and alzheimer disease (ad). |
2010-01-05 |
2023-08-12 |
Not clear |
| Futoshi Anan, Takayuki Masaki, Tsuyoshi Shimomura, Minoru Fujiki, Yoshikazu Umeno, Nobuoki Eshima, Tetsunori Saikawa, Hironobu Yoshimats. Abdominal visceral fat accumulation is associated with hippocampus volume in non-dementia patients with type 2 diabetes mellitus. NeuroImage. vol 49. issue 1. 2010-01-04. PMID:19683583. |
hippocampus volume has been quantitated with computer-assisted analysis using a magnetic resonance imaging (mri) voxel-based specific regional analysis system developed for the study of alzheimer's disease (vsrad), which yields a z-score as the end point for assessment of hippocampal volume. |
2010-01-04 |
2023-08-12 |
human |
| Mojtaba Zarei, Brian Patenaude, Jessica Damoiseaux, Ciro Morgese, Steve Smith, Paul M Matthews, Frederik Barkhof, Serge A R B Rombouts, Ernesto Sanz-Arigita, Mark Jenkinso. Combining shape and connectivity analysis: an MRI study of thalamic degeneration in Alzheimer's disease. NeuroImage. vol 49. issue 1. 2010-01-04. PMID:19744568. |
alzheimer's disease (ad) is associated with neuronal loss not only in the hippocampus and amygdala but also in the thalamus. |
2010-01-04 |
2023-08-12 |
human |
| Steffen Albrecht, Nenad Bogdanovic, Bernardino Ghetti, Bengt Winblad, Andréa C LeBlan. Caspase-6 activation in familial alzheimer disease brains carrying amyloid precursor protein or presenilin i or presenilin II mutations. Journal of neuropathology and experimental neurology. vol 68. issue 12. 2009-12-22. PMID:19915487. |
we previously demonstrated the activation of caspase-6 (casp-6) in the hippocampus and cortex in cases of mild, moderate, severe, and very severe alzheimer disease (ad). |
2009-12-22 |
2023-08-12 |
Not clear |
| Inga Kadish, Thomas van Groe. Lesion-induced hippocampal plasticity in transgenic Alzheimer's disease mouse models: influences of age, genotype, and estrogen. Journal of Alzheimer's disease : JAD. vol 18. issue 2. 2009-12-17. PMID:19584452. |
lesion-induced hippocampal plasticity in transgenic alzheimer's disease mouse models: influences of age, genotype, and estrogen. |
2009-12-17 |
2023-08-12 |
mouse |
| Inga Kadish, Thomas van Groe. Lesion-induced hippocampal plasticity in transgenic Alzheimer's disease mouse models: influences of age, genotype, and estrogen. Journal of Alzheimer's disease : JAD. vol 18. issue 2. 2009-12-17. PMID:19584452. |
we have studied entorhinal cortex lesion-induced sprouting in the hippocampus in young, adult, and aged control and transgenic alzheimer's disease model mice. |
2009-12-17 |
2023-08-12 |
mouse |
| Zheng Jing, John Caltagarone, Robert Bowse. Altered subcellular distribution of c-Abl in Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 17. issue 2. 2009-12-16. PMID:19363261. |
to further characterize a potential role of c-abl in alzheimer's disease (ad), we examined the expression and distribution of total and phosphorylated forms of c-abl in the hippocampus of ad and control subjects. |
2009-12-16 |
2023-08-12 |
human |