| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tom den Heijer, Fedde van der Lijn, Peter J Koudstaal, Albert Hofman, Aad van der Lugt, Gabriel P Krestin, Wiro J Niessen, Monique M B Bretele. A 10-year follow-up of hippocampal volume on magnetic resonance imaging in early dementia and cognitive decline. Brain : a journal of neurology. vol 133. issue Pt 4. 2010-04-27. PMID:20375138. |
with the increased interest in the use of sequential magnetic resonance images as potential surrogate biomarkers of the disease process, it has also been shown that the rate of hippocampal atrophy is higher in persons with alzheimer's disease compared to those with mild cognitive impairment and the healthy elderly. |
2010-04-27 |
2023-08-12 |
human |
| Tom den Heijer, Fedde van der Lijn, Peter J Koudstaal, Albert Hofman, Aad van der Lugt, Gabriel P Krestin, Wiro J Niessen, Monique M B Bretele. A 10-year follow-up of hippocampal volume on magnetic resonance imaging in early dementia and cognitive decline. Brain : a journal of neurology. vol 133. issue Pt 4. 2010-04-27. PMID:20375138. |
whether a higher rate of hippocampal atrophy also predicts alzheimer's disease or subtle cognitive decline in non-demented elderly is unknown. |
2010-04-27 |
2023-08-12 |
human |
| Jinte Middeldorp, Simone A van den Berge, Eleonora Aronica, Dave Speijer, Elly M Ho. Specific human astrocyte subtype revealed by affinity purified GFAP antibody; unpurified serum cross-reacts with neurofilament-L in Alzheimer. PloS one. vol 4. issue 11. 2010-04-26. PMID:19888461. |
these large astrocytes are present throughout the brain, e.g., along the subventricular zone, in the hippocampus, in the striatum and in the spinal cord of controls, alzheimer, and parkinson patients. |
2010-04-26 |
2023-08-12 |
human |
| Zang-Hee Cho, Jae-Yong Han, Seok-Il Hwang, Dae-shik Kim, Kyoung-Nam Kim, Nam-Beom Kim, Seog Ju Kim, Je-Geun Chi, Chan-Woong Park, Young-Bo Ki. Quantitative analysis of the hippocampus using images obtained from 7.0 T MRI. NeuroImage. vol 49. issue 3. 2010-04-13. PMID:19909820. |
in-vivo volumetric measurements of hippocampus have proven to be highly informative for studying various neurological diseases such as alzheimer's disease. |
2010-04-13 |
2023-08-12 |
Not clear |
| Gonzalo Sánchez-Benavides, Beatriz Gómez-Ansón, Aitor Sainz, Yolanda Vives, Manuel Delfino, Jordi Peña-Casanov. Manual validation of FreeSurfer's automated hippocampal segmentation in normal aging, mild cognitive impairment, and Alzheimer Disease subjects. Psychiatry research. vol 181. issue 3. 2010-04-12. PMID:20153146. |
manual validation of freesurfer's automated hippocampal segmentation in normal aging, mild cognitive impairment, and alzheimer disease subjects. |
2010-04-12 |
2023-08-12 |
human |
| Gonzalo Sánchez-Benavides, Beatriz Gómez-Ansón, Aitor Sainz, Yolanda Vives, Manuel Delfino, Jordi Peña-Casanov. Manual validation of FreeSurfer's automated hippocampal segmentation in normal aging, mild cognitive impairment, and Alzheimer Disease subjects. Psychiatry research. vol 181. issue 3. 2010-04-12. PMID:20153146. |
hippocampal volume is reduced in alzheimer disease (ad) and has been proposed as a possible surrogate biomarker to aid early diagnosis. |
2010-04-12 |
2023-08-12 |
human |
| Jacob Penner, Raul Rupsingh, Matthew Smith, Jennie L Wells, Michael J Borrie, Robert Barth. Increased glutamate in the hippocampus after galantamine treatment for Alzheimer disease. Progress in neuro-psychopharmacology & biological psychiatry. vol 34. issue 1. 2010-04-07. PMID:19833161. |
increased glutamate in the hippocampus after galantamine treatment for alzheimer disease. |
2010-04-07 |
2023-08-12 |
Not clear |
| Jacob Penner, Raul Rupsingh, Matthew Smith, Jennie L Wells, Michael J Borrie, Robert Barth. Increased glutamate in the hippocampus after galantamine treatment for Alzheimer disease. Progress in neuro-psychopharmacology & biological psychiatry. vol 34. issue 1. 2010-04-07. PMID:19833161. |
the purpose of this study was to determine if galantamine treatment would result in detectable hippocampal metabolite changes that correlated with changes in cognition, as measured by the mini-mental state examination (mmse) and the alzheimer disease assessment scale-cognitive subscale (adas-cog). |
2010-04-07 |
2023-08-12 |
Not clear |
| Bei Xu, Xiao-Xiu Li, Guo-Rong He, Juan-Juan Hu, Xin Mu, Shuo Tian, Guan-Hua D. Luteolin promotes long-term potentiation and improves cognitive functions in chronic cerebral hypoperfused rats. European journal of pharmacology. vol 627. issue 1-3. 2010-04-05. PMID:19857483. |
mounting evidence suggests that alzheimer's disease begins with subtle alterations of hippocampal synaptic efficacy prior to frank neuronal degeneration, which make it critical to identify ltp enhancers to slow down or stop the progression of alzheimer's disease. |
2010-04-05 |
2023-08-12 |
rat |
| Jun-ichi Satoh, Hiroko Tabunoki, Kunimasa Arim. Molecular network analysis suggests aberrant CREB-mediated gene regulation in the Alzheimer disease hippocampus. Disease markers. vol 27. issue 5. 2010-04-05. PMID:20037212. |
molecular network analysis suggests aberrant creb-mediated gene regulation in the alzheimer disease hippocampus. |
2010-04-05 |
2023-08-12 |
Not clear |
| Rukhsana Sultana, William A Banks, D Allan Butterfiel. Decreased levels of PSD95 and two associated proteins and increased levels of BCl2 and caspase 3 in hippocampus from subjects with amnestic mild cognitive impairment: Insights into their potential roles for loss of synapses and memory, accumulation of Abeta, and neurodegeneration in a prodromal stage of Alzheimer's disease. Journal of neuroscience research. vol 88. issue 3. 2010-03-30. PMID:19774677. |
decreased levels of psd95 and two associated proteins and increased levels of bcl2 and caspase 3 in hippocampus from subjects with amnestic mild cognitive impairment: insights into their potential roles for loss of synapses and memory, accumulation of abeta, and neurodegeneration in a prodromal stage of alzheimer's disease. |
2010-03-30 |
2023-08-12 |
human |
| Irene Zagol-Ikapitte, Venkataraman Amarnath, Manju Bala, L Jackson Roberts, John A Oates, Olivier Boutau. Characterization of scavengers of gamma-ketoaldehydes that do not inhibit prostaglandin biosynthesis. Chemical research in toxicology. vol 23. issue 1. 2010-03-25. PMID:20041722. |
formation of lg adducts of proteins has been demonstrated in pathologic conditions (e.g., increased levels in the hippocampus in alzheimer's disease) and during physiologic function (platelet activation). |
2010-03-25 |
2023-08-12 |
Not clear |
| Jonathan H Morra, Zhuowen Tu, Liana G Apostolova, Amity E Green, Arthur W Toga, Paul M Thompso. Comparison of AdaBoost and support vector machines for detecting Alzheimer's disease through automated hippocampal segmentation. IEEE transactions on medical imaging. vol 29. issue 1. 2010-03-22. PMID:19457748. |
comparison of adaboost and support vector machines for detecting alzheimer's disease through automated hippocampal segmentation. |
2010-03-22 |
2023-08-12 |
human |
| Caterina M Hernandez, Rakez Kayed, Hui Zheng, J David Sweatt, Kelly T Dinele. Loss of alpha7 nicotinic receptors enhances beta-amyloid oligomer accumulation, exacerbating early-stage cognitive decline and septohippocampal pathology in a mouse model of Alzheimer's disease. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 7. 2010-03-19. PMID:20164328. |
early alzheimer's disease (ad) is marked by cholinergic hypofunction, neuronal marker loss, and decreased nicotinic acetylcholine receptor (nachr) density from the cortex and hippocampus. |
2010-03-19 |
2023-08-12 |
mouse |
| Wiesje M van der Flier, Philip Schelten. Alzheimer disease: hippocampal volume loss and Alzheimer disease progression. Nature reviews. Neurology. vol 5. issue 7. 2010-03-11. PMID:19578342. |
alzheimer disease: hippocampal volume loss and alzheimer disease progression. |
2010-03-11 |
2023-08-12 |
Not clear |
| Tania Garcia, José L Esparza, M Rosa Nogués, Marta Romeu, José L Domingo, Mercedes Góme. Oxidative stress status and RNA expression in hippocampus of an animal model of Alzheimer's disease after chronic exposure to aluminum. Hippocampus. vol 20. issue 1. 2010-03-09. PMID:19405147. |
oxidative stress status and rna expression in hippocampus of an animal model of alzheimer's disease after chronic exposure to aluminum. |
2010-03-09 |
2023-08-12 |
mouse |
| Albert Tobias, Monika Saxena, Vincent Lelievr. CDK5: the "pathfinder" for new born neurons in adult hippocampus? Cell adhesion & migration. vol 3. issue 4. 2010-03-05. PMID:19855173. |
neurogenesis takes place in the mammalian hippocampus throughout the whole life and deficient adult hippocampal neurogenesis has been related to neurological conditions like alzheimer disease (ad), parkinson disease (pd) and epilepsy. |
2010-03-05 |
2023-08-12 |
Not clear |
| I Mateo, J Infante, P Sánchez-Juan, I García-Gorostiaga, E Rodríguez-Rodríguez, J L Vázquez-Higuera, J Berciano, O Combarro. Serum heme oxygenase-1 levels are increased in Parkinson's disease but not in Alzheimer's disease. Acta neurologica Scandinavica. vol 121. issue 2. 2010-03-04. PMID:19785642. |
oxidative stress is implicated in parkinson's disease (pd) and alzheimer's disease (ad), and heme oxygenase-1 (ho-1) is a potent antioxidant overexpressed in pd substantia nigra and ad cerebral cortex and hippocampus, indicating a possible up-regulation of antioxidant defenses in both neurodegenerative diseases. |
2010-03-04 |
2023-08-12 |
Not clear |
| Keun W Park, Hyung H Baik, Byung K Ji. Interleukin-4-induced oxidative stress via microglial NADPH oxidase contributes to the death of hippocampal neurons in vivo. Current aging science. vol 1. issue 3. 2010-03-04. PMID:20021392. |
thus, the present study is the first to demonstrate that il-4 generates microglial nadph oxidase-derived oxidative stress and leads to the degeneration of hippocampal neurons in vivo, as occurs in alzheimer's disease. |
2010-03-04 |
2023-08-12 |
rat |
| E J M Bierman, H C Comijs, C Jonker, P Scheltens, A T F Beekma. The effect of anxiety and depression on decline of memory function in Alzheimer's disease. International psychogeriatrics. vol 21. issue 6. 2010-03-02. PMID:19615124. |
patients with alzheimer's disease (ad) and concomitant atrophy of the hippocampus may be extra vulnerable to the consequences of psychological distress, leading to greater decline in memory function. |
2010-03-02 |
2023-08-12 |
Not clear |