| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yalin Wang, Tony F Chan, Arthur W Toga, Paul M Thompso. Multivariate tensor-based brain anatomical surface morphometry via holomorphic one-forms. Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. vol 12. issue Pt 1. 2010-06-07. PMID:20426005. |
we applied this framework to 3d mri data to analyze hippocampal surface morphometry in alzheimer's disease (ad; 26 subjects), lateral ventricular surface morphometry in hiv/aids (19 subjects) and cortical surface morphometry in williams syndrome (ws; 80 subjects). |
2010-06-07 |
2023-08-12 |
human |
| Jonathan H Morra, Zhuowen Tu, Arthur W Toga, Paul M Thompso. Lossless online ensemble learning (LOEL) and its application to subcortical segmentation. Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention. vol 12. issue Pt 2. 2010-06-07. PMID:20426141. |
loel outperformed online-adaboost and online-bagging when validated on a standardized dataset; it also performed better when used to segment the hippocampus from brain mri scans of patients with alzheimer's disease and matched healthy subjects. |
2010-06-07 |
2023-08-12 |
human |
| Alejandro F Schinder, Nicolás A Morgenster. Preview. Adult neurogenesis is altered by GABAergic imbalance in models of Alzheimer's disease. Cell stem cell. vol 5. issue 6. 2010-06-04. PMID:19951683. |
early stages of alzheimer's disease (ad) affect hippocampal function. |
2010-06-04 |
2023-08-12 |
Not clear |
| Binggui Sun, Brian Halabisky, Yungui Zhou, Jorge J Palop, Guiqiu Yu, Lennart Mucke, Li Ga. Imbalance between GABAergic and Glutamatergic Transmission Impairs Adult Neurogenesis in an Animal Model of Alzheimer's Disease. Cell stem cell. vol 5. issue 6. 2010-06-04. PMID:19951690. |
adult neurogenesis regulates plasticity and function in the hippocampus, which is critical for memory and vulnerable to alzheimer's disease (ad). |
2010-06-04 |
2023-08-12 |
mouse |
| Gang Li, Nga Bien-Ly, Yaisa Andrews-Zwilling, Qin Xu, Aubrey Bernardo, Karen Ring, Brian Halabisky, Changhui Deng, Robert W Mahley, Yadong Huan. GABAergic interneuron dysfunction impairs hippocampal neurogenesis in adult apolipoprotein E4 knockin mice. Cell stem cell. vol 5. issue 6. 2010-06-04. PMID:19951691. |
tau phosphorylation, an alzheimer's disease characteristic, and levels of neurotoxic apoe fragments were both elevated in apoe4-ki hippocampal neurons concomitant with decreased gabaergic interneuron survival. |
2010-06-04 |
2023-08-12 |
mouse |
| De-Ren Hou, Shun Wan, Jun Zhou, Kun Chen, Yi Tia. [Effect of butylphthalide on the expression of S100 and glial fibrillary acidic protein in a rat model of Alzheimer disease]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. vol 29. issue 6. 2010-05-27. PMID:19726345. |
to determine the expression of s100-beta protein and glial fibrillary acidic protein (gfap) in hippocampal astrocytes of rats with alzheimer disease (ad) model rats, and observe the effect of butylphthalide on their expression. |
2010-05-27 |
2023-08-12 |
rat |
| Jae K Ryu, James G McLarno. A leaky blood-brain barrier, fibrinogen infiltration and microglial reactivity in inflamed Alzheimer's disease brain. Journal of cellular and molecular medicine. vol 13. issue 9A. 2010-05-26. PMID:18657226. |
this study has used immunohistochemical examination of tissue obtained from alzheimer's disease (ad) brains and rat hippocampus injected with abeta(1-42) peptide to determine effects of induced inflammatory reactivity on integrity of blood-brain barrier (bbb) and viability of neurons. |
2010-05-26 |
2023-08-12 |
rat |
| Sarah M Rothman, Mark P Mattso. Adverse stress, hippocampal networks, and Alzheimer's disease. Neuromolecular medicine. vol 12. issue 1. 2010-05-24. PMID:19943124. |
adverse stress, hippocampal networks, and alzheimer's disease. |
2010-05-24 |
2023-08-12 |
Not clear |
| Avi Ring, Rita Tanso, Jens Noraber. The use of organotypic hippocampal slice cultures to evaluate protection by non-competitive NMDA receptor antagonists against excitotoxicity. Alternatives to laboratory animals : ATLA. vol 38. issue 1. 2010-05-18. PMID:20377305. |
organotypic hippocampal slice cultures were used to compare the effectiveness of the alzheimer's disease drug, memantine, the parkinson's disease drug, procyclidine, and the novel neuroprotectant, gacyclidine (gk11), against nmda-induced toxicity. |
2010-05-18 |
2023-08-12 |
Not clear |
| Alberto Serrano-Pozo, Christopher M William, Isidro Ferrer, Emmanuelle Uro-Coste, Marie-Bernadette Delisle, Claude-Alain Maurage, Christoph Hock, Roger M Nitsch, Eliezer Masliah, John H Growdon, Matthew P Frosch, Bradley T Hyma. Beneficial effect of human anti-amyloid-beta active immunization on neurite morphology and tau pathology. Brain : a journal of neurology. vol 133. issue Pt 5. 2010-05-17. PMID:20360050. |
the objectives of this study were to address the effects of anti-amyloid-beta active immunization on neurite trajectories and the pathological hallmarks of alzheimer's disease in the human hippocampus. |
2010-05-17 |
2023-08-12 |
human |
| Alberto Serrano-Pozo, Christopher M William, Isidro Ferrer, Emmanuelle Uro-Coste, Marie-Bernadette Delisle, Claude-Alain Maurage, Christoph Hock, Roger M Nitsch, Eliezer Masliah, John H Growdon, Matthew P Frosch, Bradley T Hyma. Beneficial effect of human anti-amyloid-beta active immunization on neurite morphology and tau pathology. Brain : a journal of neurology. vol 133. issue Pt 5. 2010-05-17. PMID:20360050. |
hippocampal sections from five patients with alzheimer's disease enrolled in the an1792 phase 2a trial were compared with those from 13 non-immunized braak-stage and age-matched patients with alzheimer's disease, and eight age-matched non-demented controls. |
2010-05-17 |
2023-08-12 |
human |
| Juan Zhou, Michael D Greicius, Efstathios D Gennatas, Matthew E Growdon, Jung Y Jang, Gil D Rabinovici, Joel H Kramer, Michael Weiner, Bruce L Miller, William W Seele. Divergent network connectivity changes in behavioural variant frontotemporal dementia and Alzheimer's disease. Brain : a journal of neurology. vol 133. issue Pt 5. 2010-05-17. PMID:20410145. |
alzheimer's disease, in contrast, reduced default mode network connectivity to posterior hippocampus, medial cingulo-parieto-occipital regions and the dorsal raphe nucleus, but intensified salience network connectivity. |
2010-05-17 |
2023-08-12 |
Not clear |
| Xin-Hong Duan, Jin-Ping Qiao, Yang Yang, Meng-Chao Cui, Jiang-Ning Zhou, Bo-Li Li. Novel anilinophthalimide derivatives as potential probes for beta-amyloid plaque in the brain. Bioorganic & medicinal chemistry. vol 18. issue 3. 2010-05-13. PMID:20036557. |
staining of hippocampus tissue sections from alzheimer's disease (ad) brain with the representative compound 9 indicated selective labeling of it to abeta plaques. |
2010-05-13 |
2023-08-12 |
mouse |
| Jun Ming Wang, Chanpreet Singh, Lifei Liu, Ronald W Irwin, Shuhua Chen, Eun Ji Chung, Richard F Thompson, Roberta Diaz Brinto. Allopregnanolone reverses neurogenic and cognitive deficits in mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 14. 2010-05-05. PMID:20231471. |
in this study, we investigated the efficacy of apalpha to promote neurogenesis in the hippocampal subgranular zone (sgz), to reverse learning and memory deficits in 3-month-old male triple transgenic mouse model of alzheimer's (3xtgad) and the correlation between apalpha-induced neural progenitor cell survival and memory function in 3xtgad mice. |
2010-05-05 |
2023-08-12 |
mouse |
| Jurjen W Westra, Serena Barral, Jerold Chu. A reevaluation of tetraploidy in the Alzheimer's disease brain. Neuro-degenerative diseases. vol 6. issue 5-6. 2010-05-03. PMID:19738367. |
alzheimer's disease (ad) is characterized by extensive neuronal death in distinct brain regions, including the frontal cortex and hippocampus, although the specific mechanisms of neuronal degeneration in ad remain a topic of intense scientific pursuit. |
2010-05-03 |
2023-08-12 |
human |
| Arnoud J G Knoops, Yolanda van der Graaf, Auke P A Appelman, Lotte Gerritsen, Willem P Th M Mali, Mirjam I Geerling. Visual rating of the hippocampus in non-demented elders: Does it measure hippocampal atrophy or other indices of brain atrophy? The SMART-MR study. Hippocampus. vol 19. issue 11. 2010-04-27. PMID:19253411. |
visual rating of hippocampal atrophy is often used to differentiate between normal aging and alzheimer's disease. |
2010-04-27 |
2023-08-12 |
human |
| Feng Shi, Bing Liu, Yuan Zhou, Chunshui Yu, Tianzi Jian. Hippocampal volume and asymmetry in mild cognitive impairment and Alzheimer's disease: Meta-analyses of MRI studies. Hippocampus. vol 19. issue 11. 2010-04-27. PMID:19309039. |
hippocampal volume and asymmetry in mild cognitive impairment and alzheimer's disease: meta-analyses of mri studies. |
2010-04-27 |
2023-08-12 |
Not clear |
| Feng Shi, Bing Liu, Yuan Zhou, Chunshui Yu, Tianzi Jian. Hippocampal volume and asymmetry in mild cognitive impairment and Alzheimer's disease: Meta-analyses of MRI studies. Hippocampus. vol 19. issue 11. 2010-04-27. PMID:19309039. |
numerous studies have reported a smaller hippocampal volume in alzheimer's disease (ad) patients than in aging controls. |
2010-04-27 |
2023-08-12 |
Not clear |
| Tom den Heijer, Fedde van der Lijn, Peter J Koudstaal, Albert Hofman, Aad van der Lugt, Gabriel P Krestin, Wiro J Niessen, Monique M B Bretele. A 10-year follow-up of hippocampal volume on magnetic resonance imaging in early dementia and cognitive decline. Brain : a journal of neurology. vol 133. issue Pt 4. 2010-04-27. PMID:20375138. |
hippocampal atrophy is frequently observed on magnetic resonance images from patients with alzheimer's disease and persons with mild cognitive impairment. |
2010-04-27 |
2023-08-12 |
human |
| Tom den Heijer, Fedde van der Lijn, Peter J Koudstaal, Albert Hofman, Aad van der Lugt, Gabriel P Krestin, Wiro J Niessen, Monique M B Bretele. A 10-year follow-up of hippocampal volume on magnetic resonance imaging in early dementia and cognitive decline. Brain : a journal of neurology. vol 133. issue Pt 4. 2010-04-27. PMID:20375138. |
even in asymptomatic elderly, a small hippocampal volume on magnetic resonance imaging is a risk factor for developing alzheimer's disease. |
2010-04-27 |
2023-08-12 |
human |