| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hana Saddiki, Aurore Fayosse, Emmanuel Cognat, Séverine Sabia, Sebastiaan Engelborghs, David Wallon, Panagiotis Alexopoulos, Kaj Blennow, Henrik Zetterberg, Lucilla Parnetti, Inga Zerr, Peter Hermann, Audrey Gabelle, Mercè Boada, Adelina Orellana, Itziar de Rojas, Matthieu Lilamand, Maria Bjerke, Christine Van Broeckhoven, Lucia Farotti, Nicola Salvadori, Janine Diehl-Schmid, Timo Grimmer, Claire Hourregue, Aline Dugravot, Gaël Nicolas, Jean-Louis Laplanche, Sylvain Lehmann, Elodie Bouaziz-Amar, Jacques Hugon, Christophe Tzourio, Archana Singh-Manoux, Claire Paquet, Julien Dumurgie. Age and the association between apolipoprotein E genotype and Alzheimer disease: A cerebrospinal fluid biomarker-based case-control study. PLoS medicine. vol 17. issue 8. 2020-09-24. PMID:32817639. |
the ε4 allele of apolipoprotein e (apoe) gene and increasing age are two of the most important known risk factors for developing alzheimer disease (ad). |
2020-09-24 |
2023-08-13 |
Not clear |
| Peter M Rasmussen, Rasmus Aamand, Eddie Weitzberg, Michael Christiansen, Leif Østergaard, Torben E Lun. APOE gene-dependent BOLD responses to a breath-hold across the adult lifespan. NeuroImage. Clinical. vol 24. 2020-09-21. PMID:31408838. |
age and apolipoprotein e (apoe) e4 genotype are two of the strongest known risk factors for sporadic alzheimer's disease (ad). |
2020-09-21 |
2023-08-13 |
human |
| Grégory Operto, José Luis Molinuevo, Raffaele Cacciaglia, Carles Falcon, Anna Brugulat-Serrat, Marc Suárez-Calvet, Oriol Grau-Rivera, Nuria Bargalló, Sebastián Morán, Manel Esteller, Juan Domingo Gisper. Interactive effect of age and APOE-ε4 allele load on white matter myelin content in cognitively normal middle-aged subjects. NeuroImage. Clinical. vol 24. 2020-09-21. PMID:31520917. |
considering the main role of apoe in brain lipid transport, characterizing the impact of apoe on the myelin coating is therefore of crucial interest, especially in healthy apoe-ε4 homozygous individuals, who are exposed to a twelve-fold higher risk of developing alzheimer's disease (ad), compared to the rest of the population. |
2020-09-21 |
2023-08-13 |
human |
| Jon B Toledo, Mohamad Habes, Aristeidis Sotiras, Maria Bjerke, Yong Fan, Michael W Weiner, Leslie M Shaw, Christos Davatzikos, John Q Trojanowsk. APOE Effect on Amyloid-β PET Spatial Distribution, Deposition Rate, and Cut-Points. Journal of Alzheimer's disease : JAD. vol 69. issue 3. 2020-09-18. PMID:31127775. |
there are conflicting results regarding how apoe genotype, the strongest genetic risk factor for alzheimer's disease (ad), influences spatial and longitudinal amyloid-β (aβ) deposition and its impact on the selection of biomarker cut-points. |
2020-09-18 |
2023-08-13 |
human |
| Shea J Andrews, G Peggy McFall, Andrew Booth, Roger A Dixon, Kaarin J Anste. Association of Alzheimer's Disease Genetic Risk Loci with Cognitive Performance and Decline: A Systematic Review. Journal of Alzheimer's disease : JAD. vol 69. issue 4. 2020-09-15. PMID:31156182. |
the association of apolipoprotein e (apoe) with late-onset alzheimer's disease (load) and cognitive endophenotypes of aging has been widely investigated. |
2020-09-15 |
2023-08-13 |
Not clear |
| Paola Sebastiani, Stefano Monti, Melody Morris, Anastasia Gurinovich, Tanaka Toshiko, Stacy L Andersen, Benjamin Sweigart, Luigi Ferrucci, Lori L Jennings, David J Glass, Thomas T Perl. A serum protein signature of APOE genotypes in centenarians. Aging cell. vol 18. issue 6. 2020-09-14. PMID:31385390. |
the gene apoe is associated with cognitive change and late-onset alzheimer's disease, and epidemiological studies have provided strong evidence that the e |
2020-09-14 |
2023-08-13 |
Not clear |
| Annah M Moore, Emily Mahoney, Logan Dumitrescu, Philip L De Jager, Mary Ellen I Koran, Vladislav A Petyuk, Renã As Robinson, Douglas M Ruderfer, Nancy J Cox, Julie A Schneider, David A Bennett, Angela L Jefferson, Timothy J Hohma. APOE ε4-specific associations of VEGF gene family expression with cognitive aging and Alzheimer's disease. Neurobiology of aging. vol 87. 2020-09-14. PMID:31791659. |
apoe ε4-specific associations of vegf gene family expression with cognitive aging and alzheimer's disease. |
2020-09-14 |
2023-08-13 |
Not clear |
| Alexander M Kulminski, Leonardo Shu, Yury Loika, Alireza Nazarian, Konstantin Arbeev, Svetlana Ukraintseva, Anatoliy Yashin, Irina Culminskay. APOE region molecular signatures of Alzheimer's disease across races/ethnicities. Neurobiology of aging. vol 87. 2020-09-14. PMID:31813627. |
apoe region molecular signatures of alzheimer's disease across races/ethnicities. |
2020-09-14 |
2023-08-13 |
human |
| Alexander M Kulminski, Leonardo Shu, Yury Loika, Alireza Nazarian, Konstantin Arbeev, Svetlana Ukraintseva, Anatoliy Yashin, Irina Culminskay. APOE region molecular signatures of Alzheimer's disease across races/ethnicities. Neurobiology of aging. vol 87. 2020-09-14. PMID:31813627. |
the role of even the strongest genetic risk factor for alzheimer's disease (ad), the apolipoprotein e (apoe) ε4 allele, in its etiology remains poorly understood. |
2020-09-14 |
2023-08-13 |
human |
| Jong Eun Park, Hee Jin Kim, Young-Eun Kim, Hyemin Jang, Soo Hyun Cho, Seung Joo Kim, Duk L Na, Hong-Hee Won, Chang-Seok Ki, Sang Won Se. Analysis of dementia-related gene variants in APOE ε4 noncarrying Korean patients with early-onset Alzheimer's disease. Neurobiology of aging. vol 85. 2020-09-11. PMID:31217084. |
analysis of dementia-related gene variants in apoe ε4 noncarrying korean patients with early-onset alzheimer's disease. |
2020-09-11 |
2023-08-13 |
Not clear |
| Lilah Besser, James E Galvin, Daniel Rodriguez, Teresa Seeman, Walter Kukull, Stephen R Rapp, Jennifer Smit. Associations between neighborhood built environment and cognition vary by apolipoprotein E genotype: Multi-Ethnic Study of Atherosclerosis. Health & place. vol 60. 2020-09-11. PMID:31797769. |
we examined whether neighborhood built environment (be) and cognition associations in older adults vary by apolipoprotein e (apoe) genotype, a genetic risk factor for alzheimer's disease (ad). |
2020-09-11 |
2023-08-13 |
human |
| Raphael Hesse, Maica Llavero Hurtado, Rosemary J Jackson, Samantha L Eaton, Abigail G Herrmann, Marti Colom-Cadena, Makis Tzioras, Declan King, Jamie Rose, Jane Tulloch, Chris-Anne McKenzie, Colin Smith, Christopher M Henstridge, Douglas Lamont, Thomas M Wishart, Tara L Spires-Jone. Comparative profiling of the synaptic proteome from Alzheimer's disease patients with focus on the APOE genotype. Acta neuropathologica communications. vol 7. issue 1. 2020-09-11. PMID:31862015. |
comparative profiling of the synaptic proteome from alzheimer's disease patients with focus on the apoe genotype. |
2020-09-11 |
2023-08-13 |
human |
| Jung-Min Pyun, Min Ju Kang, Younghwa Yun, Young Ho Park, SangYun Ki. APOE ɛ4 and REM Sleep Behavior Disorder as Risk Factors for Sundown Syndrome in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 69. issue 2. 2020-09-10. PMID:30958375. |
apoe ɛ4 and rem sleep behavior disorder as risk factors for sundown syndrome in alzheimer's disease. |
2020-09-10 |
2023-08-13 |
Not clear |
| Ruma Raha-Chowdhury, James W Henderson, Animesh Alexander Raha, Romina Vuono, Anastasia Bickerton, Elizabeth Jones, Robert Fincham, Kieren Allinson, Anthony Holland, Shahid H Zama. Choroid Plexus Acts as Gatekeeper for TREM2, Abnormal Accumulation of ApoE, and Fibrillary Tau in Alzheimer's Disease and in Down Syndrome Dementia. Journal of Alzheimer's disease : JAD. vol 69. issue 1. 2020-09-09. PMID:30909239. |
choroid plexus acts as gatekeeper for trem2, abnormal accumulation of apoe, and fibrillary tau in alzheimer's disease and in down syndrome dementia. |
2020-09-09 |
2023-08-13 |
Not clear |
| Chunfei Li, Ranjan Duara, David A Loewenstein, Walter Izquierdo, Mercedes Cabrerizo, Warren Barker, Malek Adjouad. Greater Regional Cortical Thickness is Associated with Selective Vulnerability to Atrophy in Alzheimer's Disease, Independent of Amyloid Load and APOE Genotype. Journal of Alzheimer's disease : JAD. vol 69. issue 1. 2020-09-09. PMID:30958345. |
greater regional cortical thickness is associated with selective vulnerability to atrophy in alzheimer's disease, independent of amyloid load and apoe genotype. |
2020-09-09 |
2023-08-13 |
Not clear |
| Na Zhao, Yingxue Ren, Yu Yamazaki, Wenhui Qiao, Fuyao Li, Lindsey M Felton, Siamak Mahmoudiandehkordi, Alexandra Kueider-Paisley, Berkiye Sonoustoun, Matthias Arnold, Francis Shue, Jiaying Zheng, Olivia N Attrebi, Yuka A Martens, Zonghua Li, Ligia Bastea, Axel D Meneses, Kai Chen, J Will Thompson, Lisa St John-Williams, Masaya Tachibana, Tomonori Aikawa, Hiroshi Oue, Lucy Job, Akari Yamazaki, Chia-Chen Liu, Peter Storz, Yan W Asmann, Nilüfer Ertekin-Taner, Takahisa Kanekiyo, Rima Kaddurah-Daouk, Guojun B. Alzheimer's Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways. Neuron. vol 106. issue 5. 2020-09-08. PMID:32199103. |
alzheimer's risk factors age, apoe genotype, and sex drive distinct molecular pathways. |
2020-09-08 |
2023-08-13 |
mouse |
| Na Zhao, Yingxue Ren, Yu Yamazaki, Wenhui Qiao, Fuyao Li, Lindsey M Felton, Siamak Mahmoudiandehkordi, Alexandra Kueider-Paisley, Berkiye Sonoustoun, Matthias Arnold, Francis Shue, Jiaying Zheng, Olivia N Attrebi, Yuka A Martens, Zonghua Li, Ligia Bastea, Axel D Meneses, Kai Chen, J Will Thompson, Lisa St John-Williams, Masaya Tachibana, Tomonori Aikawa, Hiroshi Oue, Lucy Job, Akari Yamazaki, Chia-Chen Liu, Peter Storz, Yan W Asmann, Nilüfer Ertekin-Taner, Takahisa Kanekiyo, Rima Kaddurah-Daouk, Guojun B. Alzheimer's Risk Factors Age, APOE Genotype, and Sex Drive Distinct Molecular Pathways. Neuron. vol 106. issue 5. 2020-09-08. PMID:32199103. |
evidence suggests interplay among the three major risk factors for alzheimer's disease (ad): age, apoe genotype, and sex. |
2020-09-08 |
2023-08-13 |
mouse |
| Aamira J Huq, Peter Fransquet, Simon M Laws, Joanne Ryan, Robert Sebra, Colin L Masters, Ingrid M Winship, Paul A James, Paul Lacaz. Genetic resilience to Alzheimer's disease in APOE ε4 homozygotes: A systematic review. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 15. issue 12. 2020-09-02. PMID:31506248. |
genetic resilience to alzheimer's disease in apoe ε4 homozygotes: a systematic review. |
2020-09-02 |
2023-08-13 |
Not clear |
| Aamira J Huq, Peter Fransquet, Simon M Laws, Joanne Ryan, Robert Sebra, Colin L Masters, Ingrid M Winship, Paul A James, Paul Lacaz. Genetic resilience to Alzheimer's disease in APOE ε4 homozygotes: A systematic review. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 15. issue 12. 2020-09-02. PMID:31506248. |
individuals with homozygosity for the apolipoprotein e (apoe) ε4 allele are in the highest risk category for late-onset alzheimer's disease (load). |
2020-09-02 |
2023-08-13 |
Not clear |
| Elizabeth E Blue, Andréa R V R Horimoto, Shubhabrata Mukherjee, Ellen M Wijsman, Timothy A Thornto. Local ancestry at APOE modifies Alzheimer's disease risk in Caribbean Hispanics. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 15. issue 12. 2020-09-02. PMID:31606368. |
local ancestry at apoe modifies alzheimer's disease risk in caribbean hispanics. |
2020-09-02 |
2023-08-13 |
Not clear |