| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D A Paredes, M C Cartford, B J Catlow, A Samec, M Avilas, A George, A Schlunck, B Small, P C Bickfor. Neurotransmitter release during delay eyeblink classical conditioning: role of norepinephrine in consolidation and effect of age. Neurobiology of learning and memory. vol 92. issue 3. 2009-11-05. PMID:18809505. |
neurotransmitter release during delay eyeblink classical conditioning: role of norepinephrine in consolidation and effect of age. |
2009-11-05 |
2023-08-12 |
rat |
| Wei-Gang Duan, Jing Shang, Zhen-Zhou Jiang, Jin-Cheng Yao, Yu Yun, Ming Yan, Bin Shu, Qing Lin, Ze-Pu Yu, Lu-Yong Zhan. Rho kinase inhibitor Y-27632 down-regulates norepinephrine synthesis and release in PC12 cells. Basic & clinical pharmacology & toxicology. vol 104. issue 6. 2009-08-21. PMID:19489787. |
the main aim of the study was to elucidate how rho kinase inhibitor y-27632 regulates neurotransmitter norepinephrine synthesis and release in pc12 cells when neurite outgrowth was induced. |
2009-08-21 |
2023-08-12 |
Not clear |
| Patrick Slama, Jean-Luc Boucher, Marius Réglie. N-Hydroxyguanidines oxidation by a N3S copper-complex mimicking the reactivity of Dopamine beta-Hydroxylase. Journal of inorganic biochemistry. vol 103. issue 3. 2009-04-10. PMID:19178946. |
dbh catalyses the hydroxylation of the important neurotransmitter dopamine into norepinephrine in the presence of both molecular oxygen and a reducing co-substrate. |
2009-04-10 |
2023-08-12 |
Not clear |
| R I Westphalen, R S Gomez, H C Hemming. Nicotinic receptor-evoked hippocampal norepinephrine release is highly sensitive to inhibition by isoflurane. British journal of anaesthesia. vol 102. issue 3. 2009-03-20. PMID:19189985. |
activation of hippocampal nachrs stimulates the release of norepinephrine (ne), a neurotransmitter implicated in modulating hippocampal synaptic plasticity. |
2009-03-20 |
2023-08-12 |
Not clear |
| Celia D Sladek, Zhilin Son. Regulation of vasopressin release by co-released neurotransmitters: mechanisms of purinergic and adrenergic synergism. Progress in brain research. vol 170. 2009-02-13. PMID:18655875. |
the importance of neurotransmitter interactions in determining hormone release is highlighted by the finding that simultaneous exposure to adenosine triphosphate (atp, a neurotransmitter acting on purinergic receptors) and phenylephrine (pe; to mimic norepinephrine activation of alpha1-adrenergic receptors) results in potentiation of avp release that is characterized by an increase in the peak response and conversion of a transient response to a response that is sustained for hours. |
2009-02-13 |
2023-08-12 |
Not clear |
| Yijen A Huang, Yutaka Maruyama, Stephen D Rope. Norepinephrine is coreleased with serotonin in mouse taste buds. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 49. 2009-01-12. PMID:19052199. |
norepinephrine (ne) has also been proposed to be a neurotransmitter or paracrine hormone in taste buds. |
2009-01-12 |
2023-08-12 |
mouse |
| Yan-Qiu Liu, Meng-Chun Cheng, Long-Xing Wang, Nan Zhao, Hong-Bin Xiao, Zheng-Tao Wan. Functional analysis of cultured neural cells for evaluating cold/cool- and hot/warm-natured Chinese herbs. The American journal of Chinese medicine. vol 36. issue 4. 2008-10-28. PMID:18711773. |
here, 20 chinese herbs, classified into 4 properties (hot, warm, cold and cool) of tcm, were analyzed for their ability to exhibit antioxidant action, to enhance glucose uptake by murine microglia n9 cells, and to influence neurotransmitter norepinephrine (ne) release from rat pheochromocytoma pc12 cells. |
2008-10-28 |
2023-08-12 |
rat |
| David L Christi. Functional insights into the creatine transporter. Sub-cellular biochemistry. vol 46. 2008-08-19. PMID:18652074. |
this transporter is related to the gamma-aminobutyric acid (gat) and norepinephrine (net) transporters and is part of a large gene family of na(+) - and cl(-) -dependent neurotransmitter transporters, now known as solute carrier family 6 (slc6). |
2008-08-19 |
2023-08-12 |
mouse |
| Susanne Jørgensen, Elsebet Østergaard Nielsen, Dan Peters, Tino Dyhrin. Validation of a fluorescence-based high-throughput assay for the measurement of neurotransmitter transporter uptake activity. Journal of neuroscience methods. vol 169. issue 1. 2008-06-23. PMID:18222006. |
pre-synaptic dopamine, norepinephrine and serotonin transporters (dat, net and sert) terminate synaptic catecholamine transmission through reuptake of released neurotransmitter. |
2008-06-23 |
2023-08-12 |
Not clear |
| L Keith Henry, Jens Meiler, Randy D Blakel. Bound to be different: neurotransmitter transporters meet their bacterial cousins. Molecular interventions. vol 7. issue 6. 2008-04-17. PMID:18199851. |
the neurotransmitter transporters belonging to the solute carrier 6 (slc6) family, including the gamma-aminobutyric acid (gat), norepinephrine (net), serotonin (sert) and dopamine (dat) transporters are extremely important drug targets of great clinical relevance. |
2008-04-17 |
2023-08-12 |
human |
| Devin Mueller, James T Porter, Gregory J Quir. Noradrenergic signaling in infralimbic cortex increases cell excitability and strengthens memory for fear extinction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 2. 2008-02-08. PMID:18184779. |
this is most apparent in aversive conditioning, in which the stress-related neurotransmitter norepinephrine (ne) enhances associations between sensory stimuli and fear-inducing events. |
2008-02-08 |
2023-08-12 |
Not clear |
| Jean-Pierre Vilardaga, Viacheslav O Nikolaev, Kristina Lorenz, Sébastien Ferrandon, Zhenjie Zhuang, Martin J Lohs. Conformational cross-talk between alpha2A-adrenergic and mu-opioid receptors controls cell signaling. Nature chemical biology. vol 4. issue 2. 2008-02-08. PMID:18193048. |
morphine, a powerful analgesic, and norepinephrine, the principal neurotransmitter of sympathetic nerves, exert major inhibitory effects on both peripheral and brain neurons by activating distinct cell-surface g protein-coupled receptors-the mu-opioid receptor (mor) and alpha2a-adrenergic receptor (alpha2a-ar), respectively. |
2008-02-08 |
2023-08-12 |
Not clear |
| Zheng Zhou, Juan Zhen, Nathan K Karpowich, Regina M Goetz, Christopher J Law, Maarten E A Reith, Da-Neng Wan. LeuT-desipramine structure reveals how antidepressants block neurotransmitter reuptake. Science (New York, N.Y.). vol 317. issue 5843. 2007-09-21. PMID:17690258. |
tricyclic antidepressants exert their pharmacological effect-inhibiting the reuptake of serotonin, norepinephrine, and dopamine-by directly blocking neurotransmitter transporters (sert, net, and dat, respectively) in the presynaptic membrane. |
2007-09-21 |
2023-08-12 |
human |
| Mahendra Bishnoi, Kanwaljit Chopra, Shrinivas K Kulkarn. Possible anti-oxidant and neuroprotective mechanisms of zolpidem in attenuating typical anti-psychotic-induced orofacial dyskinesia: a biochemical and neurochemical study. Progress in neuro-psychopharmacology & biological psychiatry. vol 31. issue 5. 2007-08-28. PMID:17513028. |
neurochemical analysis (neurotransmitter and their metabolite level estimation) revealed that haloperidol and chlorpromazine significantly decreased the dopamine, norepinephrine and serotonin levels in brain homogenates where as it caused a significant increase in the metabolite (vma and hva) levels in urine, which were significantly reversed by zolpidem at higher doses. |
2007-08-28 |
2023-08-12 |
rat |
| Theodore A Slotkin, Frederic J Seidle. Comparative developmental neurotoxicity of organophosphates in vivo: transcriptional responses of pathways for brain cell development, cell signaling, cytotoxicity and neurotransmitter systems. Brain research bulletin. vol 72. issue 4-6. 2007-07-24. PMID:17452286. |
chlorpyrifos elicited major transcriptional changes in genes involved in neural cell growth, development of glia and myelin, transcriptional factors involved in neural cell differentiation, camp-related cell signaling, apoptosis, oxidative stress, excitotoxicity, and development of neurotransmitter synthesis, storage and receptors for acetylcholine, serotonin, norepinephrine and dopamine. |
2007-07-24 |
2023-08-12 |
rat |
| Chi-Un Pae, Hyun-Kook Lim, Neena Ajwani, Chul Lee, Ashwin A Patka. Extended-release formulation of venlafaxine in the treatment of post-traumatic stress disorder. Expert review of neurotherapeutics. vol 7. issue 6. 2007-07-03. PMID:17563244. |
there is abundant evidence for abnormalities of both norepinephrine and serotonin neurotransmitter systems in post-traumatic stress disorder (ptsd). |
2007-07-03 |
2023-08-12 |
Not clear |
| C Sogawa, N Sogawa, J Tagawa, A Fujino, K Ohyama, M Asanuma, M Funada, S Kitayam. 5-Methoxy-N,N-diisopropyltryptamine (Foxy), a selective and high affinity inhibitor of serotonin transporter. Toxicology letters. vol 170. issue 1. 2007-06-01. PMID:17382495. |
in the present study, we investigated the actions of 5-meo-dipt against monoamine neurotransmitter transporters, including the transporters for dopamine (dat), norepinephrine (net), and serotonin (sert), using cos-7 cells heterologously expressing these transporters and rat brain synaptosomes. |
2007-06-01 |
2023-08-12 |
rat |
| G Karkoulias, O Mastrogianni, I Ilias, A Lymperopoulos, S Taraviras, N Tsopanoglou, N Sitaras, C S Flordelli. Alpha 2-adrenergic receptors decrease DNA replication and cell proliferation and induce neurite outgrowth in transfected rat pheochromocytoma cells. Annals of the New York Academy of Sciences. vol 1088. 2007-03-05. PMID:17192578. |
in addition to its role as a classical neurotransmitter, norepinephrine (ne) has been recently shown to exert an important influence on the plasticity in areas of the brain where neurogenesis persists in the adult, notably the subgranular zone (sgz) within the dentate gyrus of the hippocampus and the olfactory bulb (ob). |
2007-03-05 |
2023-08-12 |
rat |
| Daniel Palm, Kerstin Lang, Bernd Niggemann, Theodore L Drell, Kai Masur, Kurt S Zaenker, Frank Entschlade. The norepinephrine-driven metastasis development of PC-3 human prostate cancer cells in BALB/c nude mice is inhibited by beta-blockers. International journal of cancer. vol 118. issue 11. 2006-05-22. PMID:16381019. |
we have shown previously that the migration of breast, prostate, and colon carcinoma cells is enhanced by the stress-related neurotransmitter norepinephrine in vitro, and that this effect can be inhibited by the beta-blocker propranolol. |
2006-05-22 |
2023-08-12 |
mouse |
| Christoph Czermak, Michael Lehofer, Peter M Liebmann, John Trayno. [35S]GTPgammaS binding at the human dopamine D4 receptor variants hD4.2, hD4.4 and hD4.7 following stimulation by dopamine, epinephrine and norepinephrine. European journal of pharmacology. vol 531. issue 1-3. 2006-04-18. PMID:16423344. |
agonism of norepinephrine and epinephrine at the dopamine d4 receptor may indicate an important way of cross-reactivity among the different monoamine neurotransmitter systems. |
2006-04-18 |
2023-08-12 |
human |