| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M H Amiri, Huda M Shahee. Chromatophores and color revelation in the blue variant of the Siamese fighting fish (Betta splendens). Micron (Oxford, England : 1993). vol 43. issue 2-3. 2012-04-19. PMID:21803590. |
the induced color change is attributable either to the neurotransmitter releasing effects of the k-rich saline or to the direct effects of norepinephrine on the postsynaptic alpha adrenergic receptors. |
2012-04-19 |
2023-08-12 |
Not clear |
| Ashley N Hutchinson, Jie V Deng, Dipendra K Aryal, William C Wetsel, Anne E Wes. Differential regulation of MeCP2 phosphorylation in the CNS by dopamine and serotonin. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 2. 2012-04-17. PMID:21956448. |
because amph simultaneously activates multiple monoamine neurotransmitter systems, here we examined the ability of dopamine (da), serotonin (5-ht), and norepinephrine (ne) to induce pmecp2. |
2012-04-17 |
2023-08-12 |
mouse |
| Kevin Snyder, Wei-Wen Wang, Rebecca Han, Kile McFadden, Rita J Valentin. Corticotropin-releasing factor in the norepinephrine nucleus, locus coeruleus, facilitates behavioral flexibility. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 37. issue 2. 2012-04-17. PMID:21993205. |
corticotropin-releasing factor (crf), the stress-related neuropeptide, acts as a neurotransmitter in the brain norepinephrine nucleus, locus coeruleus (lc), to activate this system during stress. |
2012-04-17 |
2023-08-12 |
rat |
| Kelley S Madden, Mercedes J Szpunar, Edward B Brow. β-Adrenergic receptors (β-AR) regulate VEGF and IL-6 production by divergent pathways in high β-AR-expressing breast cancer cell lines. Breast cancer research and treatment. vol 130. issue 3. 2012-03-22. PMID:21234673. |
the β(2)-ar-selective agonist terbutaline and the endogenous neurotransmitter norepinephrine decreased vegf production by mb-231, but increased vegf production by mb-231br. |
2012-03-22 |
2023-08-12 |
human |
| Katsumasa Tanimoto, Tsuneo Takebayashi, Takeshi Kobayashi, Noritsugu Tohse, Toshihiko Yamashit. Does norepinephrine influence pain behavior mediated by dorsal root ganglia?: a pilot study. Clinical orthopaedics and related research. vol 469. issue 9. 2011-09-30. PMID:21312078. |
postganglionic neurons in the sympathetic nervous system reportedly are involved in lumbar radicular pain and release norepinephrine (ne), a neurotransmitter. |
2011-09-30 |
2023-08-12 |
Not clear |
| Jason M Dwyer, Brian J Platt, Stacey J Sukoff Rizzo, Claudine M Pulicicchio, Caitlin Wantuch, Mei-Yi Zhang, Terri Cummons, Liza Leventhal, Corey N Bender, Jean Zhang, Dianne Kowal, Shendi Lu, S Johannes R Rajarao, Deborah L Smith, Adam D Shilling, Jianyao Wang, John Butera, Lynn Resnick, Sharon Rosenzweig-Lipson, Lee E Schechter, Chad E Beye. Preclinical characterization of BRL 44408: antidepressant- and analgesic-like activity through selective alpha2A-adrenoceptor antagonism. The international journal of neuropsychopharmacology. vol 13. issue 9. 2011-09-01. PMID:20047711. |
consistent with presynaptic autoreceptor antagonism and tonic regulation of neurotransmitter release, acute administration of brl 44408 elevated extracellular concentrations of norepinephrine and dopamine, but not serotonin, in the medial prefrontal cortex. |
2011-09-01 |
2023-08-12 |
rat |
| M P Kulkarni, A R Juveka. Attenuation of Acute and Chronic Restraint Stress-induced Perturbations in Experimental Animals by Nelumbo nucifera Gaertn. Indian journal of pharmaceutical sciences. vol 70. issue 3. 2011-07-14. PMID:20046740. |
treatment groups also reverted back perturbed neurotransmitter levels (norepinephrine, dopamine and 5-hydroxytryptamine) in brain as well as increase in adrenal gland weights and atrophy of spleen caused by cold chronic stress. |
2011-07-14 |
2023-08-12 |
mouse |
| Seok Jong Hong, Yang Hoon Huh, Amanda Leung, Hyun Jin Choi, Yunmin Ding, Un Jung Kang, Seung Hyun Yoo, Reinhard Buettner, Kwang-Soo Ki. Transcription factor AP-2β regulates the neurotransmitter phenotype and maturation of chromaffin cells. Molecular and cellular neurosciences. vol 46. issue 1. 2011-07-05. PMID:20875861. |
recently, we showed that ap-2β, a member of the ap2 family, plays a critical role in the development of sympathetic neurons and locus coeruleus and their norepinephrine (ne) neurotransmitter phenotype. |
2011-07-05 |
2023-08-12 |
mouse |
| Eliot L Gardne. Addiction and brain reward and antireward pathways. Advances in psychosomatic medicine. vol 30. 2011-07-01. PMID:21508625. |
stress-triggered relapse involves (a) the central nucleus of the amygdala, the bed nucleus of the stria terminalis, and the neurotransmitter corticotrophin-releasing factor, and (b) the lateral tegmental noradrenergic nuclei of the brain stem and the neurotransmitter norepinephrine. |
2011-07-01 |
2023-08-12 |
Not clear |
| Jaspal Patil, Silvan Stucki, Juerg Nussberger, Thomas Schaffner, Susanne Gygax, Juergen Bohlender, Hans Imbode. Angiotensinergic and noradrenergic neurons in the rat and human heart. Regulatory peptides. vol 167. issue 1. 2011-06-29. PMID:21145919. |
the distinct colocalization of neuronal ang ii with dβh in the heart may indicate that ang ii participates together with norepinephrine in the regulation of cardiac functions: produced as a cardiac neurotransmitter ang ii may have inotropic, chronotropic or dromotropic effects in atria and ventricles and contributes to blood pressure regulation. |
2011-06-29 |
2023-08-12 |
human |
| Adam W Oaks, Anita Sidh. Synuclein modulation of monoamine transporters. FEBS letters. vol 585. issue 7. 2011-05-26. PMID:21396366. |
a key regulatory component of monoamine neurotransmission is re-uptake of neurotransmitter by the dopamine transporter, norepinephrine transporter, and serotonin transporter, which are common drug targets in the treatment of depression and other mood disorders. |
2011-05-26 |
2023-08-12 |
Not clear |
| Bipasha Guptaroy, Rheaclare Fraser, Aalisha Desai, Minjia Zhang, Margaret E Gneg. Site-directed mutations near transmembrane domain 1 alter conformation and function of norepinephrine and dopamine transporters. Molecular pharmacology. vol 79. issue 3. 2011-04-18. PMID:21149640. |
the human dopamine and norepinephrine transporters (hdat and hnet, respectively) control neurotransmitter levels within the synaptic cleft and are the site of action for amphetamine (amph) and cocaine. |
2011-04-18 |
2023-08-12 |
human |
| Hans Rollema, Gary G Wilson, Theodore C Lee, Joost H A Folgering, Gunnar Fli. Effect of co-administration of varenicline and antidepressants on extracellular monoamine concentrations in rat prefrontal cortex. Neurochemistry international. vol 58. issue 1. 2011-03-31. PMID:21056607. |
since varenicline neither diminished nor potentiated sertraline- or clorgyline-induced increases in neurotransmitter levels, combining varenicline with serotonergic antidepressants is unlikely to cause excessive serotonin release or to attenuate antidepressant efficacy via effects on cortical serotonin, dopamine or norepinephrine release. |
2011-03-31 |
2023-08-12 |
rat |
| Alfred Bennu. Characterization of the norepinephrine-activation of adenylate cyclase suggests a role in memory affirmation pathways. Overexposure to epinephrine inactivates adenylate cyclase, a causal pathway for stress-pathologies. Bio Systems. vol 100. issue 2. 2010-11-16. PMID:20144684. |
incubation with noradrenaline (norepinephrine) of isolated membranes of rat's brain corpus striatum and cortex, showed that ionic-magnesium (mg(2+)) is required for the neurotransmitter activatory response of adenylate cyclase [atp pyrophosphate-lyase (cyclizing) (ec 4.6.1.1)], ac. |
2010-11-16 |
2023-08-12 |
rat |
| Chiharu Sogawa, Chieko Mitsuhata, Kei Kumagai-Morioka, Norio Sogawa, Kazumi Ohyama, Katsuya Morita, Katsuyuki Kozai, Toshihiro Dohi, Shigeo Kitayam. Expression and function of variants of human catecholamine transporters lacking the fifth transmembrane region encoded by exon 6. PloS one. vol 5. issue 8. 2010-11-04. PMID:20700532. |
the transporters for dopamine (dat) and norepinephrine (net) are members of the na+- and cl--dependent neurotransmitter transporter family slc6. |
2010-11-04 |
2023-08-12 |
human |
| Xi-Jian Zhou, Jun Yang, Fu-Lin Yan, Da-Xin Wang, Xiang-Yong Li, Xiao-Qiang Fan, Fang Hao, Xi-Qing Yan, Xue-Ping Li, Hui Li, Wen-Yan Liu, Bao-Cheng Li. Norepinephrine plays an important role in antinociceptive modulation of hypothalamic paraventricular nucleus in the rat. The International journal of neuroscience. vol 120. issue 6. 2010-09-14. PMID:20504214. |
the results showed: (1) pain stimulation increased norepinephrine (ne), but not epinephrine, dopamine (da), 3,4-dihydroxyphenylacetic acid (da metabolic product), homovanilic acid (da metabolic product), serotonin (5-ht), 5-hydroxyindoleacetic acid (5-ht metabolic product), acetycholine (ach), choline (ach metabolic product), gamma-aminobutyric acid (gaba), and l-glutamate acid concentrations in the pvn perfusion liquid; (2) pvn stimulation with l-glutamate sodium, which excited local neurons only, did not influence the concentrations of the studied classical neurotransmitter and metabolic product in the pvn perfusion liquid; (3) microinjection of ne, epinephrine, or l-glutamate sodium into the pvn elevated pain threshold, and local administration of gaba decreased pain threshold in a dose-dependent manner, but pvn administration of ach, da, or 5-ht did not change pain threshold; (4) microinjection of phentolamine (alpha-receptor antagonist) or mk801 [nmda-receptor antagonist] into the pvn reduced pain threshold, and local administration of bicuculline (gaba-receptor antagonist) raised pain threshold, but pvn administration of propranolol (beta-receptor antagonist), atropine (muscarinic cholinergic receptor antagonist), 6-oh gallamine (nicotinic cholinergic receptor antagonist), fluperidol (da-receptor antagonist), or cyproheptadine (5-ht-receptor antagonist) did not alter pain threshold. |
2010-09-14 |
2023-08-12 |
rat |
| Yosuke Ohtake, Tomonori Kobayashi, Akiko Maruko, Nao Oh-Ishi, Fumihiko Yamamoto, Shinsuke Katoh, Yasuhito Ohkub. Norepinephrine modulates the zonally different hepatocyte proliferation through the regulation of transglutaminase activity. American journal of physiology. Gastrointestinal and liver physiology. vol 299. issue 1. 2010-07-12. PMID:20448147. |
a neurotransmitter, norepinephrine (ne), amplifies the mitogenic effect of epidermal growth factor (egf) in the liver by acting on the alpha(1)-adrenergic receptor coupled with g protein, galpha(h). |
2010-07-12 |
2023-08-12 |
Not clear |
| Ziarih Hawi, Aiveen Kirley, Naomi Lowe, Michael Fitzgerald, Michael Gil. Recent genetic advances in ADHD and diagnostic and therapeutic prospects. Expert review of neurotherapeutics. vol 3. issue 4. 2010-06-28. PMID:19810930. |
pharmacological, animal model and recent molecular studies support the role of genes (of minor or medium effect) from dopamine, serotonin and norepinephrine neurotransmitter systems in adhd. |
2010-06-28 |
2023-08-12 |
Not clear |
| Fangming Zhang, Rongqian Wu, Xiaoling Qiang, Mian Zhou, Ping Wan. Antagonism of alpha2A-adrenoceptor: a novel approach to inhibit inflammatory responses in sepsis. Journal of molecular medicine (Berlin, Germany). vol 88. issue 3. 2010-06-22. PMID:19894027. |
our previous studies have indicated that the release of the sympathetic neurotransmitter, norepinephrine (ne), from the gut is increased in sepsis, and that ne potentiates endotoxin-induced tumor necrosis factor (tnf)-alpha upregulation via the a subtype of alpha(2)-adrenoceptors (i.e., alpha(2a)-ar) expressed on the surface of kupffer cells. |
2010-06-22 |
2023-08-12 |
rat |
| Philip J Meas. Further strategies for treating fibromyalgia: the role of serotonin and norepinephrine reuptake inhibitors. The American journal of medicine. vol 122. issue 12 Suppl. 2010-01-27. PMID:19962496. |
unlike tcas, the newer dual reuptake inhibitors of serotonin and norepinephrine, such as the drugs approved by the us food and drug administration (fda) for fibromyalgia, milnacipran and duloxetine, do not possess significant affinity for other neurotransmitter systems, resulting in diminished side effects and enhanced tolerability. |
2010-01-27 |
2023-08-12 |
Not clear |