| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yogesh D Aher, Saraswathi Subramaniyan, Bharanidharan Shanmugasundaram, Ajinkya Sase, Sivaprakasam R Saroja, Marion Holy, Harald Höger, Tetyana Beryozkina, Harald H Sitte, Johann J Leban, Gert Lube. A Novel Heterocyclic Compound CE-104 Enhances Spatial Working Memory in the Radial Arm Maze in Rats and Modulates the Dopaminergic System. Frontiers in behavioral neuroscience. vol 10. 2016-03-04. PMID:26941626. |
the efficacy of ce-104 in blocking mat [dopamine transporter (dat), serotonin transporter (sert), and norepinephrine transporter] was determined using in vitro neurotransmitter uptake assay. |
2016-03-04 |
2023-08-13 |
human |
| Keisuke Suzuki, Masayuki Miyamoto, Tomoyuki Miyamoto, Koichi Hirat. Parkinson's disease and sleep/wake disturbances. Current neurology and neuroscience reports. vol 15. issue 3. 2015-09-29. PMID:25687697. |
disease-related pathology involving the brainstem and changes in the neurotransmitter systems (norepinephrine, serotonin, and acetylcholine) responsible for regulating sleep structure and the sleep/wake cycle play a role in emerging excessive daytime sleepiness and sleep disturbances. |
2015-09-29 |
2023-08-13 |
Not clear |
| Mary Gannon, Pulin Che, Yunjia Chen, Kai Jiao, Erik D Roberson, Qin Wan. Noradrenergic dysfunction in Alzheimer's disease. Frontiers in neuroscience. vol 9. 2015-07-03. PMID:26136654. |
the brain noradrenergic system supplies the neurotransmitter norepinephrine throughout the brain via widespread efferent projections, and plays a pivotal role in modulating cognitive activities in the cortex. |
2015-07-03 |
2023-08-13 |
Not clear |
| N Ziółkowska, B Lewczuk, B Przybylska-Gornowic. Neuropeptide Y as a presynaptic modulator of norepinephrine release from the sympathetic nerve fibers in the pig pineal gland. Polish journal of veterinary sciences. vol 18. issue 1. 2015-05-18. PMID:25928910. |
norepinephrine (ne) released from the sympathetic nerve endings is the main neurotransmitter controlling melatonin synthesis in the mammalian pineal gland. |
2015-05-18 |
2023-08-13 |
Not clear |
| Mark J Niciu, Dawn F Ionescu, Erica M Richards, Carlos A Zarat. Glutamate and its receptors in the pathophysiology and treatment of major depressive disorder. Journal of neural transmission (Vienna, Austria : 1996). vol 121. issue 8. 2015-05-12. PMID:24318540. |
monoaminergic neurotransmitter (serotonin, norepinephrine and dopamine) mechanisms of disease dominated the research landscape in the pathophysiology and treatment of major depressive disorder (mdd) for more than 50 years and still dominate available treatment options. |
2015-05-12 |
2023-08-12 |
human |
| Hongyu Chen, Dan Liu, Zhengyan Yang, Limin Sun, Que Deng, Shuo Yang, Lu Qian, Liang Guo, Ming Yu, Meiru Hu, Ming Shi, Ning Gu. Adrenergic signaling promotes angiogenesis through endothelial cell-tumor cell crosstalk. Endocrine-related cancer. vol 21. issue 5. 2015-04-13. PMID:25179535. |
in this study, we showed that the neurotransmitter norepinephrine upregulated vegf (vegfa) expression in breast cancer cells and that the culture supernatant from norepinephrine-treated breast cancer cells promoted the formation of the capillary-like network of endothelial cells. |
2015-04-13 |
2023-08-13 |
Not clear |
| Toni-Lee Sterley, Fleur M Howells, Vivienne A Russel. Nicotine-stimulated release of [3H]norepinephrine is reduced in the hippocampus of an animal model of attention-deficit/hyperactivity disorder, the spontaneously hypertensive rat. Brain research. vol 1572. 2015-02-19. PMID:24833064. |
norepinephrine, a neurotransmitter involved in attention, is highly implicated in adhd, and often targeted in the treatment thereof. |
2015-02-19 |
2023-08-13 |
rat |
| Tina Hofmaier, Anton Luf, Amir Seddik, Thomas Stockner, Marion Holy, Michael Freissmuth, Gerhard F Ecker, Rainer Schmid, Harald H Sitte, Oliver Kudlace. Aminorex, a metabolite of the cocaine adulterant levamisole, exerts amphetamine like actions at monoamine transporters. Neurochemistry international. vol 73. 2015-02-02. PMID:24296074. |
psychostimulants such as amphetamine and cocaine are illicitly used drugs that act on neurotransmitter transporters for dopamine, serotonin or norepinephrine. |
2015-02-02 |
2023-08-12 |
Not clear |
| Yong-Ku Kim, Jung-A Hwang, Heon-Jeong Lee, Ho-Kyoung Yoon, Young-Hoon Ko, Bun-Hee Lee, Han-Yong Jung, Sang-Woo Hahn, Kyoung-Sae N. Association between norepinephrine transporter gene (SLC6A2) polymorphisms and suicide in patients with major depressive disorder. Journal of affective disorders. vol 158. 2015-01-09. PMID:24655776. |
although several studies have investigated possible associations between norepinephrine neurotransmitter transporter gene (slc6a2) polymorphisms and depression, few studies have examined associations between slc6a2 polymorphisms and suicide. |
2015-01-09 |
2023-08-12 |
Not clear |
| Tae-Yong Choi, Ji Eun Kwon, Eunice Sung Durrance, Su-Hyun Jo, Se-Young Choi, Kyong-Tai Ki. Melatonin inhibits voltage-sensitive Ca(2+) channel-mediated neurotransmitter release. Brain research. vol 1557. 2014-12-03. PMID:24560601. |
we studied the effect of melatonin at high concentrations on the neurotransmitter release by monitoring norepinephrine release in pc12 cells, and excitatory postsynaptic potential in rat hippocampal slices. |
2014-12-03 |
2023-08-12 |
rat |
| Zsuzsa Jenei-Lanzl, Susanne Grässel, Georg Pongratz, Frieder Kees, Nicolai Miosge, Peter Angele, Rainer H Strau. Norepinephrine inhibition of mesenchymal stem cell and chondrogenic progenitor cell chondrogenesis and acceleration of chondrogenic hypertrophy. Arthritis & rheumatology (Hoboken, N.J.). vol 66. issue 9. 2014-10-28. PMID:24819295. |
this study was initiated to explore the role of the sympathetic neurotransmitter norepinephrine (ne) in mesenchymal stem cell (msc)-dependent and cartilage progenitor cell (cpc)-dependent chondrogenesis. |
2014-10-28 |
2023-08-13 |
Not clear |
| Minsoo Han, Chiman Song, Nakcheol Jeong, Hoh-Gyu Hah. Exploration of 3-Aminoazetidines as Triple Reuptake Inhibitors by Bioisosteric Modification of 3-α-Oxyazetidine. ACS medicinal chemistry letters. vol 5. issue 9. 2014-09-15. PMID:25221656. |
the inhibitory reuptake activities against serotonin (5-ht), norepinephrine (ne), and dopamine (da) neurotransmitters were measured by the neurotransmitter transporter uptake assay kit using the human embryonic kidney 293 (hek293) cells stably transfected with the respective three kinds of human transporters (hsert, hnet, and hdat). |
2014-09-15 |
2023-08-13 |
human |
| Elizabeth S Bucher, Megan E Fox, Laura Kim, Douglas C Kirkpatrick, Nathan T Rodeberg, Anna M Belle, R Mark Wightma. Medullary norepinephrine neurons modulate local oxygen concentrations in the bed nucleus of the stria terminalis. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 34. issue 7. 2014-09-02. PMID:24714037. |
here we investigate the local role of the neurotransmitter norepinephrine in the ventral bed nucleus of the stria terminalis (vbnst) of the anesthetized rat by measuring o₂, which is delivered during functional hyperemia. |
2014-09-02 |
2023-08-13 |
rat |
| Mercedes J Szpunar, Kathleen A Burke, Ryan P Dawes, Edward B Brown, Kelley S Madde. The antidepressant desipramine and α2-adrenergic receptor activation promote breast tumor progression in association with altered collagen structure. Cancer prevention research (Philadelphia, Pa.). vol 6. issue 12. 2014-07-31. PMID:24309563. |
emotional stress activates the sympathetic nervous system (sns) and release of the neurotransmitter norepinephrine to promote breast tumor pathogenesis. |
2014-07-31 |
2023-08-12 |
mouse |
| Xiu-Ping Sun, Si-Di Li, Zhe Shi, Teng-Fei Li, Rui-Le Pan, Qi Chang, Chuan Qin, Xin-Min Li. Antidepressant-like effects and memory enhancement of a herbal formula in mice exposed to chronic mild stress. Neuroscience bulletin. vol 29. issue 6. 2014-07-18. PMID:24132797. |
in addition, syg restored the decreased monoamine neurotransmitter concentrations (serotonin, dopamine, norepinephrine and acetylcholine) induced by cms in the prefrontal cortex. |
2014-07-18 |
2023-08-12 |
mouse |
| José R Maldonad. Neuropathogenesis of delirium: review of current etiologic theories and common pathways. The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. vol 21. issue 12. 2014-07-18. PMID:24206937. |
in general, the most commonly described neurotransmitter changes associated with delirium include deficiencies in acetylcholine and/or melatonin availability; excess in dopamine, norepinephrine, and/or glutamate release; and variable alterations (e.g., either a decreased or increased activity, depending on delirium presentation and cause) in serotonin, histamine, and/or γ-aminobutyric acid. |
2014-07-18 |
2023-08-12 |
Not clear |
| Jakob D Wikstrom, Kiana Mahdaviani, Marc Liesa, Samuel B Sereda, Yaguang Si, Guy Las, Gilad Twig, Natasa Petrovic, Cristina Zingaretti, Adam Graham, Saverio Cinti, Barbara E Corkey, Barbara Cannon, Jan Nedergaard, Orian S Shiriha. Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure. The EMBO journal. vol 33. issue 5. 2014-04-25. PMID:24431221. |
the sympathetic neurotransmitter norepinephrine (ne) induced complete and rapid mitochondrial fragmentation in ba, characterized by drp1 phosphorylation and opa1 cleavage. |
2014-04-25 |
2023-08-12 |
mouse |
| Jose V Menani, Laurival A De Luca, Alan Kim Johnso. Role of the lateral parabrachial nucleus in the control of sodium appetite. American journal of physiology. Regulatory, integrative and comparative physiology. vol 306. issue 4. 2014-04-10. PMID:24401989. |
selective lpbn manipulation of other neurotransmitter systems [e.g., serotonin, cholecystokinin (cck), corticotrophin-releasing factor (crf), glutamate, atp, or norepinephrine] greatly enhances nacl intake when accompanied by additional treatments that induce either thirst or sodium appetite. |
2014-04-10 |
2023-08-12 |
rat |
| M Khalilur Rahman, M Iqbal Choudhary, M Arif, M Monzur Morshe. Dopamine-β-Hydroxylase Activity and Levels of Its Cofactors and Other Biochemical Parameters in the Serum of Arsenicosis Patients of Bangladesh. International journal of biomedical science : IJBS. vol 10. issue 1. 2014-04-08. PMID:24711750. |
dopamine-β-hydroxylase (dbh) is a neurotransmitter (catecholamine)-mediating enzyme, which catalyzes the formation of norepinephrine from dopamine. |
2014-04-08 |
2023-08-13 |
Not clear |
| Marc N Potenz. Neurobiology of gambling behaviors. Current opinion in neurobiology. vol 23. issue 4. 2014-02-27. PMID:23541597. |
multiple neurotransmitter systems (norepinephrine, serotonin, dopamine, opioid and glutamate) and brain regions (ventral striatum, ventromedial prefrontal cortex, insula, among others) have been implicated in gambling and pg. |
2014-02-27 |
2023-08-12 |
Not clear |